Rational Vaccines
Universal City, US · Founded 2015 · Delaware corporation · 1 known investors
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Rational Vaccines is an investigational-stage infectious disease company developing live attenuated viral immunotherapeutic and prophylactic vaccine candidates targeting herpes simplex virus 1 (HSV-1) and 2 (HSV-2) infections. It aims to treat, prevent, and diagnose herpes and herpes-related diseases, and is also applying its technology toward COVID-19.
Founders & leadership
Rational Vaccines was founded in 2015 by Agustin Fernandez III and William P. Halford.

Investors · 1
How we know: AAF Management Ltd.'s portfolio page · the VCSheet dataset · Not right? Tell us
Reported raises · per SEC filings
Form D private placements$27.8M disclosed across 5 rounds · 2015–2020
▶$11.7MraisedJun 2022 · 16 investors · BiotechnologyRule 506(b)
- Olivier JarryExecutive Officer
- Agustin FernandezExecutive Officer, Director
- David BrindleyExecutive Officer
- Jeffrey MaddenDirector
- Diane AbbittDirector
- Jason CammDirector
- Offering amount
- $11.7M
- Amount sold
- $11.7M
- First sale
- Mar 2020
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$6.8MraisedSep 2018 · 9 investors · PharmaceuticalsRule 506(b)
- Agustin Fernandez IIIExecutive Officer, Director
- Jason CammDirector
- Offering amount
- $30M
- Amount sold
- $6.8M
- First sale
- Sep 2018
- Incorporated
- Corporation, Delaware, 2015
- Federal exemptions
- 06b
▶$8.2MraisedSep 2017 · 25 investors · PharmaceuticalsRule 506(b)
- Jason CammDirector
- Agustin Fernandez IIIExecutive Officer, Director
- Offering amount
- $8.2M
- Amount sold
- $8.2M
- First sale
- Aug 2017
- Incorporated
- Corporation, Delaware, 2015
- Federal exemptions
- 06b
▶$364KraisedOct 2016 · 5 investors · PharmaceuticalsRule 506(b)
- William P. HalfordExecutive Officer, Director
- Agustin Fernandez IIIExecutive Officer, Director
- Offering amount
- $2M
- Amount sold
- $364K
- First sale
- Oct 2016
- Incorporated
- Corporation, California, 2015
- Federal exemptions
- 06b
▶$700KraisedSep 2015 · 10 investors · PharmaceuticalsRule 506(b)
- Paul BohmExecutive Officer
- Agustin Fernandez IIIExecutive Officer, Director
- Aziz FriedrichExecutive Officer
- William P. HalfordExecutive Officer, Director
- Offering amount
- $700K
- Amount sold
- $700K
- First sale
- Apr 2015
- Incorporated
- Corporation, Delaware, 2015
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Related companies · 1
Companies working in the same space as Rational Vaccines.
Non-dilutive funding · 3 SBIR/STTR awards
Federal grants — no equity taken| Agency | Phase | Year | Amount |
|---|---|---|---|
| National Institutes of Health (NIH)National Institutes of Health | Phase I | 2023 | $291.5K |
| National Institutes of Health (NIH)National Institutes of Health | Phase I | 2023 | $288.1K |
| National Institutes of Health (NIH)National Institutes of Health | Phase I | 2022 | $269.6K |
Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are competitive federal R&D grants and contracts — non-dilutive capital alongside any venture rounds above.
In the news
Frequently asked questions
- What does Rational Vaccines do?
- Rational Vaccines is an investigational-stage infectious disease company developing live attenuated viral immunotherapeutic and prophylactic vaccine candidates targeting herpes simplex virus 1 (HSV-1) and 2 (HSV-2) infections. It aims to treat, prevent, and diagnose herpes and herpes-related diseases, and is also applying its technology toward COVID-19.
- Who founded Rational Vaccines?
- Rational Vaccines was founded by Agustin Fernandez III, William P. Halford in 2015.
- Who are Rational Vaccines's investors?
- Rational Vaccines's investors include AAF Management Ltd..
- How much funding has Rational Vaccines raised?
- Rational Vaccines has disclosed $27.8M raised across 5 rounds.
- Where is Rational Vaccines headquartered?
- Rational Vaccines is headquartered in Universal City, US.


