Big Brain Holdings — Full Portfolio

Upexi is a Solana-focused treasury company that acquires, holds, and stakes SOL tokens to give investors digital asset exposure through a publicly traded equity security (UPXI).

Crypto & Web3FintechTampa, US

Andrew Nordstrud(Chief Financial Officer)AMAllan Marshall(Chief Executive Officer)inRobert Hackett(Executive Officer, Director)

BoardGene Salkind(Director)Lawrence H. Dugan(Director)Thomas C. Williams(Director)

Co-investorsWHWhite Star CapitalGSGSR

CrossCurve is a cross-chain DeFi protocol built around its Cross-chain Data Protocol (CDP), a messaging and transport layer for transferring data and liquidity between blockchains, supporting products such as a cross-chain bridge, liquidity protocol, and DEX.

Crypto & Web3Developer ToolsFintech

BPBoris Povar(Founder)in

Co-investorsDRDraper AssociatesFEFenbushi CapitalGBGBV CapitalMAMarshland CapitalBIBitDAOMAMantle Network+1 more

decent.land builds onchain data infrastructure — an "onchain data center" for storing, verifying, and computing with blockchain data at scale, secured by Arweave and HyperBEAM.

Crypto & Web3Data & InfrastructureDeveloper Tools

Co-investorsFOForesight VenturesLDLD CapitalNANarwhal VenturesTSTsingTech VenturesY Y Combinator

Eywa provides a MetaLayer and API for building in DeFi, offering a single integration for cross-chain routing, deep liquidity access, and automated on-chain operations across EVM and non-EVM networks with gasless execution.

Crypto & Web3Developer ToolsFintech

Co-investorsFEFenbushi CapitalGBGBV CapitalMAMarshland CapitalAFAfford.CapitalMUMulana Capital

Helika builds Helika Evolve, a brand-safe AI character platform that lets IP owners deploy interactive characters trained on their approved content to engage fans in real time across Discord, web, social, and community channels.

AI & Machine LearningGamingMarketing Tech

AAnton(Founder & CEO)IIlya(CPO)

Co-investorsDIDiagramPAPantera CapitalBUBuilder CapitalFEFenbushi CapitalSPSparkle VenturesFEFermion

Aethir operates a distributed cloud compute platform providing enterprise-grade GPU resources for AI model training, fine-tuning, inference, and low-latency cloud gaming.

AI & Machine LearningCloud ComputingCrypto & Web3

MRMark Rydon(Founder)in

Co-investorsANAndromeda CapitalANAnimoca BrandsBUBuilder CapitalCVCVP NoLimitIMImpossible FinanceINInception Capital (ex OP Crypto)+8 more

Agility Robotics develops and deploys humanoid robots for warehouse automation and logistics operations.

AI & Machine LearningHardwareLogistics & Supply ChainRoboticsSalem, US

JHJonathan Hurst(Co-founder & Chief Robot Officer)inDSDamion Shelton(Co-Founder & Chairman of the Board)in

BoardBLBruce Leak(Director)inMOMatthew Ocko(Director)in

Co-investorsDCDCVC (Data Collective)HAHARPER COURT VENTURESMAManhattan Venture PartnersMFMFV PartnersNVNVenturesPLPlayground Global+6 more

AheadComputing develops high-performance 64-bit RISC-V application processor cores designed to maximize per-core CPU performance for AI, cloud, client, mobile, and edge workloads.

AI & Machine LearningDeep TechSemiconductorsBeaverton, US

DMDebbie Marr(Founder)inJPJonathan Pearce(Founder)inSSSrikanth Srinivasan(Founder)

BoardGRGreg Reichow(Director)inJim Keller(Director)

Co-investorsCACambium CapitalECEclipse VenturesMEMESHTRTrousdale VenturesFUFundomoMAMaverick Capital+1 more

Ritual is a research lab combining artificial intelligence, cryptography, algorithmic game theory, and distributed systems.

AI & Machine LearningCrypto & Web3Deep Tech

Niraj Pant(Co-Founder)Akilesh Potti(Co-Founder)

Co-investorsARArchetypeBOBollinger Investment GroupEDEdessa CapitalHYHypersphere VenturesLVLvna CapitalMHMH Ventures+1 more

Akave provides isolated, persistent object storage for AI and machine learning workloads, enabling customers to store datasets, model weights, and training artifacts with tenant-level data isolation and compliance capabilities.

AI & Machine LearningCloud ComputingData & InfrastructureDeep Tech

SVStefaan Vervaet(Founder)inASAngelo Schalley(Founder)inDaniel León(Founder)in

Co-investorsCVCVP NoLimitNONo Limit Holdings (NLH)

Ambient builds an open, decentralized network for AI inference that ensures every answer can be verified and no single provider can control model delivery.

AI & Machine LearningCloud ComputingData & InfrastructureDeveloper Tools

Antigma builds AI agent technology and infrastructure optimized for rapid experimentation and iteration.

AI & Machine LearningDeep TechDeveloper Tools

Apptronik builds humanoid robots designed to perform repetitive, physically taxing, and dangerous tasks in warehousing and manufacturing environments, aiming to free workers for higher-value activities.

Advanced ManufacturingAI & Machine LearningHardwareRoboticsAustin, US

JCJeff Cardenas(CEO)inNicholas Arden Paine(Executive Officer, Director)

BoardClarence Gordon Daugherty, IV(Director)HLHoward Lee Morgan(Director)inGeorge Samuel Rose(Director)

Co-investorsASAssembly VenturesATAtinum Investment Co. Ltd.B B Capital GroupB4B4 CapitalBABaseTwoCACapital Factory+22 more

Arch is a Bitcoin-native chain and execution environment (ArchVM) that lets institutions and users borrow, lend, earn yield, swap, and build financial applications that settle directly to Bitcoin without bridging, wrapping, or leaving self-custody.

Crypto & Web3Data & InfrastructureFintech

Amine ElQaraoui(Founder)in

Co-investorsMUMulticoin CapitalASAsymmetricCACartaCICiti VenturesCRCraft VenturesMEMenlo Ventures+3 more

Argument builds systems for verifiable computing by combining zero-knowledge cryptography, formal verification, and distributed consensus technologies.

Crypto & Web3Deep TechDeveloper ToolsEnterprise SoftwareBoston, US

JBJohn Burnham(Founder)inGBGabriel Barreto(Founder)inSBSamuel Burnham(Founder)in

Co-investorsSASamsung NextVAVarys CapitalY Y CombinatorLOLombardstreet Ventures

Arweave is a decentralized ecosystem that offers grants and investment opportunities through various organizations including non-profits, DAOs, and venture studios to support projects and developers building on its network.

Cloud ComputingCrypto & Web3Data & InfrastructureFintechLondon, GB

Sam Williams(Founder & CEO)in

Co-investors1K1k(x)1K1kxA1a16z cryptoADAdvanced BlockchainANAndreessen HorowitzARArrington Capital+24 more

The Avalanche Foundation is a non-profit organization that supports innovation and growth in the Avalanche ecosystem through grants, programs, and strategic support for developers, entrepreneurs, and communities building on the Avalanche blockchain platform.

Crypto & Web3Data & InfrastructureDeveloper ToolsEnterprise SoftwareFintech

EGEmin Gun Sirer(Founder)in

Co-investorsA1a16z cryptoAEAegis VentuesANAndreessen HorowitzANAndromeda CapitalBABaseTwoBIBig Candle Capital+25 more

Bio Protocol is a decentralized science (DeSci) platform where people can fund, develop and govern tokenized early-stage scientific research from universities, companies and researchers.

AI & Machine LearningBiotechCrypto & Web3

Co-investorsBIBinance LabsPFPfizer VenturesPOPolymorphic CapitalSESerafundSISignature VenturesSMSMAPE Capital+3 more

Bitflow is a decentralized exchange and DEX aggregator built on the Stacks/Bitcoin ecosystem, letting users trade BTC, sBTC, SIP10 tokens and Runes, provide liquidity, and set up recurring swaps.

Crypto & Web3Fintech

DFDylan Floyd(Founder)inNicholas Thompsonin

Co-investorsMAMarin Digital VenturesBIBitcoin Startup LabGEGenblock CapitalNENewman CapitalPOPortal VenturesTYTykhe Block Ventures

BitRobot is a decentralized network that coordinates researchers, hardware operators, and compute providers to advance embodied AI and robotics R&D.

AI & Machine LearningCrypto & Web3Robotics

Michael Cho

Co-investorsTITioga Capital PartnersFAFabric VenturesPRProtocol LabsZEZee Prime Capital

Bulk is a decentralized trading platform that aims to combine the decentralized custody of a DEX with the execution performance of a centralized exchange.

Crypto & Web3

Co-investors6T6th Man VenturesCHChapter OneWIWintermuteRORobot VenturesSTStride Ventures

Pump.fun is a platform that lets anyone create and trade coins, with open access to buy and sell from launch.

Crypto & Web3

Co-investors6T6th Man VenturesD1D1 VenturesLALattice CapitalWIWintermute

ZAR is a financial app that lets people in countries with volatile local currencies send, hold, and spend US dollars.

ConsumerCrypto & Web3Fintech

Cookie3 uses blockchain and analytics to turn on-chain user behavior into marketing insights for brands while maintaining data privacy.

AdTechCrypto & Web3Data & InfrastructureMarketing TechTallinn, EE

Wojciech Piechociński(Founder)inFWFilip Wielanier(Founder)in

Co-investorsAWAweh VenturesCACastrum CapitalGRGravity TeamHAHartmann CapitalJSJsquareLDLD Capital+2 more

Cookie3 is a crypto marketing analytics platform that combines onchain data (transactions, wallet interactions, dApp usage) with offchain social and engagement metrics to provide user analytics, KOL (key opinion leader) intelligence, and deep research for crypto projects.

Crypto & Web3Data & InfrastructureMarketing Tech

FWFilip Wielanier(Founder)in

Co-investorsBIBitDAOGRGrizzly CapitalMAMantle NetworkPOPointer.CapitalGRGravity TeamHAHartmann Capital+4 more

Crossmint builds developer tools that let companies, AI agents, and users work with blockchain and stablecoin rails without dealing with the underlying complexity.

Crypto & Web3Developer ToolsFintechSaaSNew York, US

AGAlfonso Gómez-Jordana Mañas(Founder)inRFRodri Fernández Touza(Founder)in

Co-investors6T6th Man VenturesABAbstract VenturesCOCommerce VenturesGMGMO VenturePartnersHAHash3 CapitalINInformed Ventures Advisors, Llc+2 more

Raiku develops a lightweight Solana validator client that provides ahead-of-time compute reservations and just-in-time MEV bundle processing, enabling financial institutions and market makers to achieve enterprise-grade execution reliability and performance in cryptocurrency markets.

Crypto & Web3Data & InfrastructureFintech

Robin A. Nordnes(Founder & CEO)Konrad Stepniak(Head of Engineering)Waleed Al Zuhair(Head of Growth)Saikat Das(Chief Marketing Officer)

Co-investorsFIFigmentREReciprocal Ventures

Utexo develops infrastructure for bringing USD Tether (USDT) to Bitcoin, leveraging RGB and Lightning Network technologies to enable Bitcoin-native stablecoin payments.

Crypto & Web3Data & InfrastructureFintech

Viktor Ihnatiuk(Co-founder)Chris Hutchinson(Co-founder)Renat Skitsan(Co-founder)

Co-investorsFUFulgur VenturesMAMaven 11PAPaper Ventures

Daxo Robotics develops a highly dexterous, tendon-driven robotic hand with 120 tendens and high degrees of freedom, offered with a Python-first API, ROS wrapper, and simulation assets.

Deep TechHardwareRobotics

Tom Zhang Jiahao(Founder)in

Co-investorsNENextFab Ventures

Dymension is a decentralized layer-1 protocol that lets creators launch tokens and convert them into full blockchains called RollApps, with built-in DEX and rollup-as-a-service tooling.

Crypto & Web3Data & InfrastructureDeveloper Tools

Co-investorsCOCogitent VenturesCOContinue CapitalTPTPC Club (The presale club)TPTPC Ventures

Dyna develops general-purpose robots powered by foundation models that adapt across environments and learn new skills rapidly, with deployment across a fleet that continuously improves.

AI & Machine LearningDeep TechRobotics

LGLindon Gao(Founder)inJMJason Ma(Founder)inYork Yang(Founder)in

Co-investorsCRCRV (Charles River Ventures)HCHCVCININCE CapitalLGLG Technology VenturesSASamsung NextSASancus Ventures+5 more

Enhanced develops a scientific platform that combines sports performance analysis with human potential optimization.

AI & Machine LearningConsumerDigital HealthHealthtechSports TechWellness & Fitness

MMMaximilian Martin(Co-Founder & CEO)inChristian Angermayer(Co-Founder & Executive Chairman)DADr Aron D'Souza(Founder)

Entangle is a Web3 interoperability layer providing cross-chain messaging, data feeds and a universal token standard for dApps.

Dubai, AE

Faisal Mehrban(Founder)

Co-investorsBIBitDAOCACastrum CapitalCOCogitent VenturesLBLBANK LabsMAMantle NetworkRHRhinevall Capital+2 more

Exabits provides AI compute infrastructure by refining GPU assets (such as GB200s, H100s, H200s, and RTX5090s) from leading manufacturers to support AI workloads.

AI & Machine LearningCloud ComputingData & Infrastructure

Co-investorsBLBloccelerate VCEDEdessa CapitalFOFOMO VenturesGEGenerative VenturesLBLBANK LabsMOMoonhill Capital+4 more

exo connects Macs and workstations into a single local inference cluster, automatically discovering devices, mapping network topology, and splitting AI models across device memory to run frontier models on-premises.

AI & Machine LearningDeep TechDeveloper Tools

Co-investorsARArchetypeBRBreedPRPragma VenturesRORobot Ventures

Flashbots is a research and development organization that mitigates negative externalities from Maximal Extractable Value (MEV) on blockchains, primarily Ethereum, through infrastructure and tools for block building, transaction protection, and MEV distribution.

Crypto & Web3Data & InfrastructureDeveloper Tools

Co-investorsBLBlueYard CapitalDRDragonflyETEthereal Ventures Management Ltd.FAFabric VenturesFAFactionFEFenbushi Capital+12 more

Fortytwo operates a sovereign, participant-owned AI network that uses swarm inference to combine heterogeneous AI models into a single networked intelligence.

AI & Machine LearningCloud ComputingDeep Tech

AFAlex Firsov(Founder)in

Co-investorsEVEv3 Ventures Llc

FrodoBots turns tele-operation of robots into a game, using gamers' actions as training data to develop embodied foundational AI models.

AI & Machine LearningGamingRobotics

GLIF provides DeFi and liquid staking infrastructure for the Filecoin network, including staking pools and a loyalty rewards program tied to its $GLF token.

Crypto & Web3Data & InfrastructureFintech

Jonathan Schwartz(Founder)

Co-investorsMUMulticoin CapitalZEZee Prime CapitalSTStruck CapitalFIFinTech CollectivePRProtocol Labs

Grass operates a network that lets users share their unused internet bandwidth with verified institutions in exchange for rewards paid as points, Grass Tokens, or USDC.

ConsumerCrypto & Web3Data & Infrastructure

Co-investorsCHChronos VenturesCOCogitent VenturesCVCVP NoLimitLALattice CapitalNONo Limit Holdings (NLH)HAHack VC

GTE is a decentralized exchange platform that enables trading of stocks, crypto, and commodities from a single account on a blockchain-based system, offering centralized-exchange-level speed and performance with decentralized properties.

Crypto & Web3FintechNew York City, US

Matteo Lunghi(Founder)

Co-investorsPAParadigmRORobot VenturesMAMaven 11MIMITONMIMitonCWIWintermute

Hawksight collects trading signals submitted by a distributed community of contributors and runs analytics over them to rank and filter the results.

Crypto & Web3FintechSingapore, SG

Bradian Muliadi(CEO)inLorenzo Ampil(CTO)in

Co-investorsENEntrepreneur FirstSKSkyVision CapitalSOSolar Eco FundCSCSP DAOFOFollow[the]SeedGLGlobal Founders Capital+4 more

Helius is Solana's leading infrastructure provider offering high-performance RPC nodes, transaction sending services, and data streaming tools for developers, traders, and applications.

Crypto & Web3Data & InfrastructureDeveloper ToolsToronto, CA

Nicolas Pennie(Founder)inLiam Vovk(Founder)inMert M(Founder)

BoardAYAnatoly Yakovenkoin

Co-investorsHAHaun VenturesFOFoundation CapitalFOFounders Fund6T6th Man VenturesCHChapter OnePRPropel Venture Partners+13 more

Hemi is a dual-layer Bitcoin protocol that enables smart contract execution and programmability by combining Bitcoin's Proof-of-Work security with Ethereum-level functionality.

Crypto & Web3Data & InfrastructureDeveloper ToolsFintech

Matthew Roszak(Co-Founder, Hemi Labs)Jeff Garzik(Principal Engineering, Hemi Labs)Max Sanchez(Lead Architect, Hemi Labs)

Co-investorsIMImpossible FinanceTRTRGCWEWeb3com VenturesPOPortal

Hyperbolic operates an AI cloud platform that provides developers and researchers with affordable, on-demand access to GPU compute and AI models, in part by tapping underutilized consumer-grade hardware.

AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsNew York, US

JZJasper Zhang(CEO & Co-Founder)inYJYuchen Jin(CTO & Co-Founder)inYue Zhang(Executive Officer, Director)

Co-investorsAMAmbush CapitalFAFactionGSGSRLOLongHash VenturesSASamsung NextVAVariant Fund+4 more

Ika is a decentralized MPC network on Solana that introduces "dWallets," a primitive splitting signing authority between users and Solana programs to control native assets on other blockchains without bridges or centralized custody.

AI & Machine LearningCrypto & Web3Data & Infrastructure

OSOmer Sadika(Founder)in

Co-investorsCOCollider VenturesCVCVP NoLimitFLFlowdeskLVLvna CapitalNONo Limit Holdings (NLH)NONode Capital+3 more

Inco provides a privacy layer for blockchain networks, enabling privacy solutions that adapt to different chains, use cases, and regulatory requirements.

AI & Machine LearningCrypto & Web3CybersecurityDeveloper Tools

Remi

Co-investorsCOCoinbase VenturesGSGSRSYSymbolic CapitalZEZero Knowledge Validator (ZKV)1K1kxSCScript Capital+1 more

Inference Labs develops cryptographic verification systems for autonomous AI agents, robots, and other autonomous systems, enabling auditable and trustworthy decision-making through zero-knowledge proofs and verifiable computing.

AI & Machine LearningCrypto & Web3Deep Tech

CGColin Gagich(Founder)inRCRon Chan(Founder)in

Co-investorsEDEdessa CapitalLVLvna CapitalARArche Capital VentureDIDigital Asset CapitalMEMechanism Capital

Initia provides blockchain infrastructure that connects full-stack applications through integrated protocols and aligned economic incentives.

Crypto & Web3Data & Infrastructure

Co-investorsA.A.Capital VenturesFIFigmentHAHack VCNANascentTHTheory Ventures

Kash operates a mobile payment system that processes transactions directly from bank accounts to merchants, bypassing credit card networks and intermediaries to reduce transaction fees.

FintechSan Francisco, US

GFGeoff Flarity(Founder/COO)in

Co-investorsY Y CombinatorCOCoinbase VenturesFAFabric VCKOKosmos VenturesMOMoonrock Capital

Kash is a social prediction market platform that combines betting mechanics with blockchain technology to enable trustless peer-to-peer wagering.

AI & Machine LearningConsumerCrypto & Web3FintechMarketplaces

LMLucas Martin Calderon(Founder & CEO)in

Legend is a social trading platform where users copy trades from other traders, follow live alerts, and trade with up to 50x leverage.

Crypto & Web3FintechSocial

Co-investorsELElectric CapitalMIMitonC

Mach Industries designs and manufactures defense systems including unmanned aerial systems, precision munitions, high-altitude surveillance platforms, and propulsion testing capabilities for military applications.

Defense TechHardwareHuntington Beach, US

ETEthan Thornton(Executive Officer, Director)inBrendan Cooney(Executive Officer)in

BoardKRKeith Rabois(Director)inGLGeoff Lewis(Director)inLewis Geoff(Director)

Co-investorsALAloft VCBEBedrockCHChampion Hill VenturesCOCoalitionDEDefense AngelsFOFOG Ventures+10 more

Magna is an all-in-one platform for crypto companies to launch, manage, and scale tokens, offering token operations, treasury management, stablecoin management, and distribution across a global web3 ecosystem.

Crypto & Web3Developer ToolsEnterprise SoftwareFintechSaaSNew York City, US

BFBruno Faviero(Founder)inAKArun Kirubarajan(Founder)in

Co-investorsBEBehind Genius VenturesDODorm RoomMAMarin Digital VenturesOLOlive Tree CapitalY Y CombinatorASAsymmetric+2 more

MeanFi provides DeFi infrastructure and a treasury toolkit for businesses and individuals to manage crypto assets on the Solana blockchain, offering features such as multisig wallets, real-time token streaming, payroll, vesting, lending, and payment collection.

Crypto & Web3Data & InfrastructureFintech

Co-investorsOPOpen Opportunity FundSOSolar Eco FundDEDeFiance CapitalGEGerstenbrot CapitalMEMEXCPRPrimeBlock Ventures+1 more

MegaETH is a high-performance blockchain that settles on Ethereum, offering over 100,000 transactions per second and sub-10-millisecond block times.

Crypto & Web3Data & InfrastructureFintech

SKShuyao Kong (孔姝尧)(Founder)in

Co-investorsFIFigmentMIMitonCRORobot Ventures

Merge Labs is a research lab developing brain-computer interfaces that connect with neurons using molecules instead of electrodes and non-invasive modalities like ultrasound, integrated with AI.

AI & Machine LearningBiotechDeep TechSan Antonio, US

Andrew Trickett(Executive Officer, Director)Franklin Lyons(Executive Officer, Director)

BoardLMLew Moorman(Director)in

Co-investorsANAntiSCSciFi VCSTStarship VenturesBABain CapitalFIFifty YearsINInterface Fund+1 more

Minteo provides stablecoin infrastructure backed by liquid reserves, enabling cross-border money transfers in emerging markets, particularly Latin America.

Crypto & Web3Fintech

WDWilliam Duran(Founder)in

Co-investorsFAFabric VenturesG2G20 VenturesVAVarys CapitalDUDune VenturesFJFJ LabsSESevenX Ventures+1 more

Mitosis is a blockchain protocol that provides a cross-chain settlement and liquidity layer, letting users deposit capital once and access it across multiple chains without bridging.

Crypto & Web3Data & InfrastructureFintech

Co-investorsTPTPC Club (The presale club)TPTPC VenturesAMAmber GroupFOForesight Ventures

Moku creates Moki, a collection of 8887 hand-assembled NFT characters built from 900+ traits, and develops games around them including an AI Fantasy Arena, a snack-combining puzzler, and an async autobattler.

AI & Machine LearningCrypto & Web3Gaming

Bruce Wasicsko(Founder)in

Co-investorsARArca FundsBABankless VenturesACACORN BIOVENTURESBLBlocktower CapitalCOContango Digital AssetsFOFormless Capital+4 more

Monad is a high-performance EVM-compatible blockchain designed for fast, low-cost transactions.

Cloud ComputingCrypto & Web3Data & Infrastructure

KHKeone Hon(Founder & CEO)in

Co-investorsALAlphaLab CapitalAMAmbush CapitalARArchetypeBABankless VenturesBLBloccelerate VCBOBODL+23 more

Mysten Labs builds infrastructure and tools for web3, focusing on making decentralized systems secure, reliable, and ready for mass adoption.

Cloud ComputingCrypto & Web3Deep TechDeveloper ToolsPalo Alto, US

AAAdeniyi Abiodun(Founder)inKostas Kryptos Chalkias(Founder)inSBSam Blackshear(Founder)inECEvan Cheng(Founder)in

Co-investorsA1a16z cryptoALAlumni VenturesANAndreessen HorowitzARArrington CapitalBABasecamp FundCHChamaeleon+22 more

NEAR is an open blockchain infrastructure powering the agent economy, providing cross-chain execution, confidential settlement, and private inference capabilities.

AI & Machine LearningCloud ComputingCrypto & Web3Miami, US

IPIllia Polosukhin(Co-Founder)in

Co-investorsA.A.Capital VenturesA1a16z cryptoACAccompliceADAdvanced BlockchainAMAmbush CapitalAMAmplify Partners+36 more

Nillion is a decentralized secure computing network that uses privacy-enhancing technologies to store and process sensitive data by distributing trust across nodes.

AI & Machine LearningCrypto & Web3Data & Infrastructure

AYAndrew Yeoh(Founder)in

Co-investorsARARKN venturesCHChapter OneFLFlowdeskFOFOMO VenturesINInception Capital (ex OP Crypto)KUKube VC+14 more

Nirvana Robotics builds humanoid robots and learning systems designed to operate in the physical world.

AI & Machine LearningHardwareRoboticsNew York City, US

Octra provides encrypted computation infrastructure for blockchain, AI, and applications.

AI & Machine LearningCrypto & Web3Data & Infrastructure

Co-investorsBUBuilder CapitalFIFinality Capital Partners

Open Forest Protocol builds data-backed financing and monitoring mechanisms for nature-based climate solutions, working with afforestation and reforestation projects tied to the voluntary carbon market.

Climate TechCrypto & Web3Impact & Social GoodZug, Canton Zug

FFFrederic Fournier(Executive Officer)inMichael David Kelly(Executive Officer)Olha Dyka(Executive Officer)Aureline Natacha Grange(Executive Officer)

BoardJeremy Daniel Epstein(Director)

Co-investorsCACapria VenturesMEMercy Corps VenturesVAValor Capital GroupNONot Boring CapitalSHShima CapitalÜBÜbermorgen Ventures

Outdefine provides a governed decisioning and execution layer for clinical trial teams, using trial-trained AI inference and workflow agents to support site feasibility ranking, study risk monitoring, and real-world evidence analysis.

AI & Machine LearningBiotechHealthtech

Co-investorsVEVery Serious VenturesFOFormless CapitalJUJump Crypto

Panoptic is an onchain DeFi protocol for perpetual options — options without expiry dates — built on Uniswap liquidity, letting traders deploy leveraged options strategies and depositors earn yield through curator-managed vaults.

Crypto & Web3Fintech

Co-investorsADAdvanced BlockchainCOCoinbase VenturesDIDivergenceGRGreenfieldGUgumi Cryptos Capital (gCC)SESevenX Ventures

Parallel operates AI-driven simulation games and extraction shooter games set in the Parallel Universe.

AI & Machine LearningGaming

PAParag Agrawal(Founder & CEO)

Co-investorsCOCoinbase VenturesCOCollab+CurrencyOSOSS CapitalPAParadigmWWWWVentures

Parcl provides daily real estate market signals, ownership data, and tools for analyzing how housing markets move, including a portfolio-search tool for finding single-family rental portfolios and data/resolution services for housing-related prediction markets.

Data & InfrastructureFintechPropTechNew York City, US

JLJason Lewris(Founder)in

Co-investorsARArchetypeCOCoinbase VenturesDRDragonflyHAHack VCLALAB VenturesMEMetastable+4 more

Perle provides expert-driven data services for AI teams, supplying credentialed specialists to handle data collection, labeling, quality assurance, evaluation, and RLHF/RLAIF for tasks that generic crowd-worker vendors can't judge.

AI & Machine LearningData & InfrastructureEnterprise SoftwareRoboticsSan Francisco, US

ARAhmed Rashad(Founder)in

Co-investorsACACTAI VenturesALAlphaLab CapitalBRBreedCACaladanCOCoinFundPAPaper Ventures+2 more

Persona AI develops industrial humanoid robots for skilled physical tasks such as welding, grinding, inspection, fabrication, and maintenance in environments like shipyards, construction sites, and energy infrastructure.

AI & Machine LearningHardwareRobotics

Co-investorsBABaseTwoK5K50 VenturesSOSound Media VenturesZEZero Infinity PartnersFAFathomIBIBK Capital

Poseidon develops unmanned aerial vehicles for cargo logistics, specifically wave-skimming seagliders designed to reduce the cost per ton-mile of air freight.

Deep TechHardwareLogistics & Supply ChainSan Francisco, US

Parker Tenney(Cofounder)inDavid Zagaynov(Cofounder)in

Co-investorsCACade VenturesDRDraper AssociatesGOGoAhead VenturesSTStarship VenturesTATamarack GlobalTQTq Ventures Llc

Rain provides real-time financial guidance to employees by monitoring cash flow, analyzing spending patterns, and offering personalized financial advice.

AI & Machine LearningEnterprise SoftwareFintechHR TechSaaS

ABAlex Bradford(Founder & CEO)in

Co-investorsAUAurum Venture PartnersCLClear Haven Capital ManagementENEnsemble VCETEthos VCVUVU Venture PartnersBEBessemer Venture Partners+7 more

Reflect is a stablecoin API and SDK that lets developers add yield-bearing savings accounts, launch branded yield-bearing stablecoins, and offer opt-in insurance and risk tranching within their apps.

Crypto & Web3Developer ToolsFintech

Reflect Orbital is developing satellite-based mirrors that redirect natural sunlight from space to illuminate specific areas on Earth on demand, with adjustable brightness and scheduling.

CleantechEnergySpace TechHawthorne, US

BNBen Nowack(Executive Officer, Director)inTSTristan Semmelhack(Executive Officer, Director)in

BoardSMShaun Maguire(Director)inJWJosh Wolfe(Director)in

Co-investorsALAlumni VenturesLULux CapitalSTStarship VenturesWIWinklevoss CapitalSESequoia Capital

Sleektext is a news and information platform dedicated to World of Warcraft coverage, offering game updates, player guides, strategies, and tournament information to WoW players globally.

GamingMedia & Entertainment

Co-investorsBABAM VenturesDODorm RoomBIBinance LabsEMEmirates ConsortiumGEGenblock CapitalJUJungle Ventures+4 more

Solana is a blockchain network designed for high-performance internet capital markets, payments, and cryptocurrency applications.

Crypto & Web3Data & InfrastructureFintechSan Francisco, US

AYAnatoly Yakovenko(Solana Founder & Solana Labs CEO)inAlan Yu

Co-investors1K1k(x)1K1kx50500 GlobalA1a16z cryptoABAbstract VenturesAEAegis Ventues+37 more

Solayer is a hardware-accelerated blockchain and financial platform that enables trading of crypto, equities, and commodities on a high-performance L1 blockchain, along with a crypto-native payment card for global spending.

Crypto & Web3Fintech

Co-investorsFOFOMO VenturesHAHack VCPRProtagonistPOPolychain Capital

Solayer operates a hardware-accelerated Solana validator that offers staking services through its sSOL liquid staking token, capturing maximum MEV rewards for depositors.

Crypto & Web3Data & InfrastructureFintech

Co-investorsBOBorderless VentureFOFOMO VenturesLVLvna CapitalMAMaelstromPRProtagonist

Stacks is a blockchain platform that enables smart contracts and decentralized applications to leverage Bitcoin as a secure base layer through a Layer 2 solution, offering developer tools and a programming language called Clarity.

Crypto & Web3Developer ToolsNew York, US

RSRyan Shea(Co-founder)inMAMuneeb Ali(Co-founder)in

BoardAWAlbert Wenger(Director)in

Co-investorsBRBreyer CapitalCOCompoundCOContinue CapitalDIDigital Currency GroupDRDraper AssociatesELEllipti+20 more

Teralink builds high-speed communication systems for satellites, drones, and other airborne platforms.

Deep TechHardwareSpace Tech

AAAli Alqaraghuli(Founder)in

The Graph organizes and indexes blockchain data through a decentralized network, providing web3 developers with fast, cost-efficient access to smart contract data via subgraphs and GraphQL queries.

Crypto & Web3Data & InfrastructureDeveloper Tools

Co-investorsAGAGE CryptoANAndromeda CapitalANAngelONE CapitalBOBollinger Investment GroupBOBootNodeCHChapter One+25 more

Tsavorite designs and manufactures the Omni Processing Unit, a hardware and software architecture for AI workloads that scales from edge devices to datacenter and exascale systems.

AI & Machine LearningHardwareSemiconductors

STShalesh Thusoo(Founder, Chief Executive Officer)inSMSupriya Madan(Co-Founder, Chief Development Officer)inGWGuntram Wolski(Co-Founder, Chief Operating Officer)inSKSarvagya Kochak(Co-Founder, VP Business Development)inSSShirish Seetharam(Co-Founder, VP Software Development)inMUMike Uhler(Chief Technology Officer)in

Co-investorsPAPavestonePRPresidio Ventures

USD.ai offers a stablecoin-based platform for financing AI compute infrastructure, letting users earn yield or borrow to fund the machines behind AI data centers.

AI & Machine LearningCrypto & Web3Fintech

Co-investorsALAlphaLab CapitalBRBreedCACaladanFRFramework Ventures

Vulcan Elements manufactures rare earth magnets for critical applications in defense, semiconductors, satellites, data centers, and industrial equipment.

Advanced ManufacturingDefense TechNew MaterialsBenson, US

JMJohn Maslin(Executive Officer, Director)inDaniel Aronowitz(Executive Officer, Director)

BoardDBDaniel Borok(Director)in

Co-investorsBLBlindspot Ventures Management CoDODorm RoomDUDuke Capital PartnersFIFifth Down CapitalGLGlynn Capital ManagementJUJunipero+6 more

Wormhole offers Native Token Transfers (NTT), an open framework for token issuers to create, transfer, and customize tokens across multiple blockchains without relying on pooled liquidity.

Crypto & Web3Data & InfrastructureDeveloper ToolsFintech

RBRobinson Burkey(Founder)in

Co-investorsBOBorderless VentureDEDelta BlockchainFIFigmentMUMulticoin CapitalPAParaFi CapitalRRRR2 Capital+4 more

XPLA is a blockchain mainnet, transitioning to a rebrand called CONX, focused on connecting value across culture, finance, and technology in the web3 space.

Crypto & Web3

Co-investorsGOGOAL VenturesPLPlay VenturesTRTRANSCENDFUFunPlusHAHashedIVIVC

YottaLabs provides on-demand, production-ready GPU cloud infrastructure for AI teams, offering GPU pods, virtual machines, serverless scaling, an AI gateway that routes across model providers, and model quantization for training and inference.

AI & Machine LearningCloud ComputingData & Infrastructure

Co-investorsGEGenerative VenturesKUKuCoin Labs

Co-investorsCOCollab+Currency