Arboretum Ventures — Full Portfolio

SI-BONE develops medical devices for treating sacroiliac (SI) joint dysfunction and chronic low back pain, targeting patients and physicians.

HealthtechMedical DevicesSan Jose, US

Mark Reiley(Director)inJWJeffrey W. Dunn(Executive Officer, Director)Robert E. Johnson(Executive Officer)Dan Murray(Executive Officer)LALaura A. Francis(Chief Executive Officer)

BoardTimothy E. Davis(Director)

PartnerTPTim Petersen· led

Co-investorsMOMontreux Equity PartnersOROrbiMed

Convergent Dental is a privately owned dental equipment and technology company whose flagship product, Solea, is a CO2 all-tissue laser cleared by the FDA that offers anesthesia-free, blood-free, and suture-free dental procedures.

Enterprise SoftwareHardwareHealthtechMedical DevicesNatick, US

Nathan P. Monty(Executive Officer, Director)inMichael J. Cataldo(Executive Officer, Director)RGRob Gershon(Chief Executive Officer)inMCMark Collins(Chief Financial Officer)inTHTodd Hornsby(Chief Commercial Officer)in

BoardBart Doedens(Director)

Board seatTimothy PetersenTimothy B. Petersen· per SEC Form D

Co-investorsLRLRVHealthTRTrinity Capital

Boomerang Medical develops a bioelectric neuromodulation device to treat bowel urgency symptoms in patients with ulcerative colitis and other inflammatory bowel disease.

BiotechDigital HealthMedical DevicesMountain View, US

Co-investorsHAHatteras Venture Partners

Orasis is a pharmaceutical company developing drugs for the eye, operating in the ophthalmology and eyecare space.

BiotechHealthtechMedical Devices

Co-investorsMAMaverick Ventures IsraelVIVisionary VenturesCACatalio Capital ManagementJOJohnson & Johnson Innovation – JJDCLILifeSci Venture PartnersSESequoia Capital+1 more

PAK BioSolutions builds automated systems and single-use flow kits for end-to-end continuous purification of biopharmaceuticals, running four continuous purification stages simultaneously for a stated 4X productivity gain over batch methods.

Advanced ManufacturingBiotechHardwareBurke, US

Pezzini Joanna(President)inKHKevin Hill-Byrne(Co-Founder & CTO)in

HealthtechSt Louis, US

Andrea M. Clegg(Executive Officer)Louis Silverman(Executive Officer, Director)

BoardBLBarbara Lubash(Director)inMichael Mikolajczyk(Director)David N. Schopp(Director)

Board seatTimothy B. Petersen· per SEC Form D · $7.3M raise · filed Jul 2015

Co-investorsVEVersant Ventures

Allay Therapeutics develops localized pain management technology designed to deliver several weeks of post-surgical pain relief.

BiotechHealthtechMedical DevicesSan Jose, US

AGAdam Gridley(Executive Officer, Director)inKristen Howells(Executive Officer)inJosh Makower(Director)Tak Cheung(Director)inKarun D. Naga(Executive Officer, Director)

BoardLeighton Read(Director)

Board seatPMPaul McCreadie· per SEC Form D

Co-investorsLILightstone VenturesNENew Enterprise Associates (NEA)SGSGInnovateCLClavystBio

ArborMetrix provides a software platform for healthcare quality improvement that aggregates and analyzes patient data to help providers, payers, and health systems optimize clinical and financial performance, reduce adverse events, and improve outcomes.

Data & InfrastructureEnterprise SoftwareHealthtechAnn Arbor, US

JBJohn Birkmeyer, M.D.(Director)BFBrett Furst(Executive Officer, Director)inChristian Birkmeyer(Executive Officer)Steven Richvalsky(Executive Officer)

BoardPMPaul McCreadie(Director)inAnthony Grover(Director)

Board seatTimothy Petersen· per SEC Form D

Co-investorsIDID Ventures

Francis Medical is a medical device company developing minimally invasive urological cancer treatments using water vapor ablation technology, initially focused on prostate cancer with its Vanquish Water Vapor Ablation System.

BiotechDigital HealthHealthtechMedical DevicesMaple Grove, US

MHMichael Hoey(Founder)inMichael Kujak(Executive Officer, Director)Christopher Dixon(Chief Medical Officer)in

BoardAndrew Cleeland(Director)David Adair(Director)in

Board seatJGJan Garfinkle· per SEC Form D

Co-investorsSOSolas BioVentures

Health Scholars (UpSkillAI) provides AI- and XR-based immersive training, using voice-powered VR simulations that let teams practice protocols hands-free.

AI & Machine LearningEdTechFuture of WorkWestminster, US

BRIAN GILLETT(Executive Officer)ROBERT SEHRING(Director)ANGELA MCFARLAND(Executive Officer)SCOTT JOHNSON(Executive Officer, Director)LAURA MEDINA(Executive Officer)RIKARD STEIBER(Director)

Board seatThomas Shehab· per SEC Form D

Co-investorsCACapital Midwest FundSEService Provider CapitalCLClarevia VenturesVEVenture Investors Health Limited Partnership

Koya Medical develops wearable compression therapy devices, including its Dayspring system, for treating conditions such as lymphedema, chronic venous insufficiency, and deep vein thrombosis.

HardwareHealthtechMedical DevicesOakland, US

ADAnand Doraiswamy(Executive Officer, Director)in

BoardJBJosh Baltzell(Director)in

Board seatJGJan Garfinkle· per SEC Form D

Co-investorsAPAphelion CapitalSCScientific Health DevelopmentZÜZühlke VenturesCACadence Healthcare VenturesOROrbiMed

Motif Neurotech develops a therapeutic brain-computer interface using minimally invasive neuromodulation to treat difficult-to-treat mental health conditions such as depression.

BiotechDeep TechDigital HealthHealthtechMedical DevicesHouston, US

SSSameer Sheth(Founder)inSSSunil Sheth(Founder)NHNick Halper(Chief Operating Officer)inSGSteve Goetz(Chief Technology Officer)inAAAnthony Arnold(Director)in

BoardJRJacob Robinson(Co-founder & CEO)in

Board seatThomas M. Shehab· per SEC Form D

Co-investorsFEFeatures Capital HoldingsPSPsyMed VenturesTMTMC Venture FundXEXEIA Venture PartnersCACapital FactoryDIDivergent Capital+4 more

Pioneering the development of prescription digital therapeutics.

HealthtechBoston, US

CMCorey McCann(Executive Officer, Director)inAntoun Nabhan(Executive Officer)Christopher Guiffre(Executive Officer)

BoardASAndrew Schwab(Director)inZLZack Lynch(Director)in

Board seatTimothy PetersenTPTim Petersen· per SEC Form D · $51M raise · filed Jan 2018

Co-investorsJAJAZZ Venture Partners5A5AM VenturesGEGeneral CatalystOCOCA VenturesSESeyen CapitalSOSoftBank Group+1 more

Seattle, US

Ronald Seubert(Executive Officer, Director, Promoter)ECEvan Castiglia(Executive Officer)inJVJoseph Victor(Executive Officer, Director)Frank Witney(Director)Eric Kaldjian(Executive Officer)

BoardRSRobert Shepler(Director)in

Board seatJGJan Garfinkle· per SEC Form D

Co-investors5A5AM VenturesF-F-Prime CapitalSOSofinnova VenturesTETelegraph Hill Partners

Reprieve Cardiovascular develops a decongestion management system that uses real-time patient data to guide and personalize diuretic therapy for fluid removal in heart failure patients.

Digital HealthHealthtechMedical DevicesMilford, US

TFTony Fields(Executive Officer)ABAdam Bartnik(Executive Officer)inMark Pacyna(Executive Officer, Director)inJim Dillon(Executive Officer, Director)Hanson S. Gifford III(Director)Gregory W Mann(Executive Officer)

Board seatJGJan Garfinkle· per SEC Form D

Co-investorsLILightstone VenturesRERex Health VenturesDEDeerfield Management CompanyGEGenesis Venture CapitalSASante Ventures

Strata Oncology develops precision oncology biomarkers and predictive diagnostic tools for cancer treatment, including treatment response scores for antibody-drug conjugates (ADCs) and an Immunotherapy Response Score for anti-PD-1/PD-L1 therapies.

AI & Machine LearningBiotechDigital HealthMedical DevicesAnn Arbor, US

Daniel Rhodes(Executive Officer, Director)Matthew Martin(Executive Officer)Jeffrey Williams(Executive Officer, Director)

BoardCOChristopher O'Donnell(Director)inDavid Rubin(Director)inJPJames Pavlik(Director)in

Board seatJGJan GarfinkleNicole Walker· per SEC Form D

Co-investorsPFPfizer Venture InvestmentsDEDeerfield Management CompanyMEMerck Global Health Innovation FundPFPfizer Ventures

SonarMD provides a care management platform for chronic diseases, starting with gastroenterology, that combines AI technology with human support to detect clinical deterioration early and help specialists intervene before emergencies.

AI & Machine LearningDigital HealthHealthtechMedical DevicesSaaSChicago, US

Lawrence R. Kosinski(Founder and Board Member)inBHBETH HOUCK(Executive Officer, Director)inJohn Starr(Executive Officer)Devin Gross(Executive Officer, Director)

Board seatCharity TarnThomas M ShehabTom Shehab· per SEC Form D

Co-investorsBLBlue Hour VenturesHYHypothesisNUNueterra CapitalTETensility Venture PartnersBLBlueCross BlueShield Venture Partners

Virtual Incision develops a miniaturized robotic-assisted surgery (miniRAS) system called MIRA, designed to fit within hospitals' existing infrastructure.

BiotechHealthtechMedical DevicesRoboticsLincoln, US

Dmitry Oleynikov(Director)Shane Farritor(Executive Officer, Director)JPJohn P. Murphy(Executive Officer, Director)inMukund Srinivasan(Executive Officer)in

BoardFred Robertson(Director)

Board seatTom Shehab· per SEC Form D

Co-investorsENEndeavour VisionINInvest NebraskaINInVivium CapitalBABaird CapitalPRPrairieGold Venture Partners

410 Medical makes LifeFlow, a hand-operated rapid infuser that lets clinicians quickly deliver blood or fluids to critically ill patients needing volume resuscitation.

HardwareHealthtechMedical DevicesDurham, US

Mark Donald Piehl(Executive Officer, Director)KCKYLE CHENET(Executive Officer, Director)in

BoardJTJEFF TERRELL(Director)inSTANLEY D. LYNALL(Director)FGFRED GOLDWATER(Director)inMAYANK TANEJA(Director)in

Co-investorsBABallad VenturesCUCU Healthcare Innovation FundDUDuke Capital PartnersOSOSF VenturesWOWolfpack Investor NetworkBIBios Partners+1 more

Akadeum manufactures GMP-compliant ancillary materials for cell and gene therapy applications, specializing in microbubble-based negative selection products.

Advanced ManufacturingBiotechDeep TechHealthtechMedical DevicesAnn Arbor, US

Kalyan Handique(Executive Officer, Director)JYJohn Younger(Executive Officer, Director)inJames Militello(Executive Officer)

BoardJeffrey S. Williams(Director)PDPaul D'Amato(Director)inDKDan Kidle(Director)in

Co-investorsBEBeringeaBEBerkeley CatalystBLBlueStone Venture PartnersCACANTILEVER INVESTORSELeLab VenturesHEHemisphere Ventures LLC+7 more

AtaCor Medical develops extravascular lead systems for cardiac rhythm management, including a novel extravascular defibrillation lead for EV-ICD therapy and an implantable, extracardiac pacemaker.

HardwareHealthtechMedical Devices

Alan(Co-founder & Vice President of Clinical, Regulatory & Quality)

Co-investorsBABayMed Venture PartnersBRBroadview VenturesCACatalyst Health VenturesHAHatteras Venture Partners

Avation Medical manufactures the Vivally System, an FDA-cleared wearable device that uses transcutaneous tibial nerve stimulation to treat overactive bladder and urge urinary incontinence in at-home 30-minute sessions.

Digital HealthHealthtechMedical DevicesValencia, US

Manish Vaishya, PhD(Chief Executive Officer, Co-Founder & Board Member)JSJill Schiaparelli(Executive Officer, Director)inKevin Wasserstein(Director)

BoardThomas Shehab, MD(Director)

Co-investorsANAngelini VenturesSHShangBay Capital LLCAVAvestria Ventures

Non-surgical, non-pharmacologic devices to induce weight loss

Co-investorsDEDelos CapitalLOLongitude CapitalHIHighland Capital PartnersSASante Ventures

Digital HealthHealthtechMedical DevicesSanta Barbara, US

Justin Bellante(Executive Officer, Director, Promoter)Brent Peus(Executive Officer)

BoardBrandon Cady(Director)Jeff Closs(Director)Patrick Cua(Director)Kathleen Shanahan(Director)

PartnerPMPaul McCreadie· led

Co-investorsHEHealthQuest Capital

BrightSpec develops molecular rotational resonance (MRR) spectroscopy instruments and software that identify and quantify gas-phase molecules from complex mixtures without front-end separation.

BiotechDeep TechHardwareWaltham, US

RGRick Gordon(CEO)inWalter Colsman(Executive Officer, Director)JAFFRAY WOODRIFF(Director)ROBERT LLOYD(Executive Officer, Director)THOMAS JONES(Director)DAVID MCDANIEL(Executive Officer, Director)

Co-investorsGEGenoa VenturesMEMedvest Capital

Cardiosense develops wearable sensing hardware and deep-learning algorithms that convert physiological signals into clinical insights for cardiovascular disease detection and management.

AI & Machine LearningDigital HealthHealthtechMedical DevicesChicago, US

OIOmer Inan(Co-founder, Chief Scientific Officer)inACAndrew Carek(Co-founder, Chief Technical Officer)inAGAmit Gupta(Co-founder, Advisor)inMEMozziyar Etemadi(Co-founder, Head of AI)OIOmer Inan, PhD(Co-founder, Chief Scientific Officer)inACAndrew Carek, PhD(Co-founder, Chief Technical Officer)in

Co-investorsBABayMed Venture PartnersBRBroadview VenturesCRCross-Border Impact VenturesLALaerdal Million Lives FundOSOSF VenturesPOPortal Innovations+1 more

ConcertoCare provides coordinated in-home and center-based medical, behavioral, and social care for seniors and adults with complex care needs who have Medicare, Medicare Advantage, or Medicare+Medicaid coverage.

Digital HealthHealthtechLongevity

Co-investorsATAtento CapitalOBObvious VenturesSTSteelSky VenturesADAddeparDEDeerfield Management CompanyVAVast Ventures+1 more

Endogenex is a clinical-stage medical device company developing the pulsENDO system, which applies non-thermal pulsed electric field to reset the body's metabolic signaling and improve function in people with type 2 diabetes.

Digital HealthHealthtechMedical DevicesMinneapolis, US

SPStacey Pugh(Leadership (CEO))inChris Sorli, MD, PhD(Chief Medical Officer)inKrissy Wright(Chief Financial Officer)inLian Cunningham, MD, PhD(VP Clinical Affairs)inMHMelanie Hess(Regulatory Affairs Leadership)inMCMatt Cambronne(Technical/Engineering Leadership)in

Co-investorsINIntuitive VenturesLOLongitude CapitalLULumira Ventures

Enumera Molecular develops technology and a platform for simplified, lower-cost workflows that enable liquid biopsy and high-dimensional omics assays for laboratories.

BiotechDeep TechHealthtechMedical DevicesAnn Arbor, US

MCMatthew Cooper(CEO & Co-founder)inElaine Heron(Director)

BoardDKDan Kidle(Director)inSundaresh Brahmasandra(Director)

EQRx was a Cambridge, MA biopharma that aimed to sell lower-priced novel drugs; it was acquired by Revolution Medicines in 2023.

Co-investorsANAndreessen HorowitzARARCH Venture PartnersGVGV (Google Ventures)BABain Capital

BiotechAnn Arbor, US

Antonio M. Gotto, Jr.(Director)Tim M. Mayleben(Executive Officer, Director)Gilbert S. Omenn(Director)Daniel Janney(Director)Dov A. Goldstein(Director)Roger S. Newton(Director)

Co-investorsAIAisling CapitalALAlta PartnersARARCHIMED JapanASAsset Management CompanyCACanaan PartnersLOLongitude Capital+2 more

Software that detects subtle vital-sign changes to warn medical professionals of post-operative patient deterioration risk.

JBJen Baird, NACD.DC(Founder)inMSMark Salamango(Founder)in

Co-investorsINInvest MichiganWMWMU Biosciences Research & Commercialization CenterCUCultivation Capital

Flosonics Medical makes FloPatch, a wireless wearable Doppler ultrasound device that assesses a patient's carotid arterial pulse in real time to give clinicians hemodynamic data for fluid resuscitation decisions.

Digital HealthHardwareMedical Devices

JEJoe Eibl(Founder)in

Co-investorsAMAmplify CapitalGEGenesys CapitalIGiGan PartnersNENew Leaf Venture PartnersRBRBCx

Hicuity Health is an independent provider of acute and critical care telemedicine services, including tele-ICU, in-patient telemetry monitoring, virtual nursing, virtual sitter, and smart device monitoring.

Digital HealthHealthtechMedical DevicesSt. Louis, US

IKIsabelle Kopec(Co-founder)LSLou Silverman(Chairman & CEO)inACAndrea Clegg(CFO & Compliance Officer)inJKJason Kressel(Chief Operating Officer)inSPSergio Piñon(Head of Enterprise Clinical Applications)inCDCorey Danko(Head of IT Infrastructure)in

PartnerTPTim Petersen· led

Co-investorsCOCorewell Health Ventures

Inogen is a global medical technology company that develops, manufactures, and markets portable oxygen concentrators and other respiratory therapy devices for home use.

Digital HealthHardwareHealthtechMedical Devices

ABAli Bauerlein(Founder)in

Intellicyt (now part of Sartorius) develops the iQue high-throughput screening (HTS) flow cytometry platform, which combines sampling hardware and analysis software to generate multiplexed cell phenotype and function data from 96- or 384-well plates.

BiotechHardwareMedical Devices

Co-investorsSASaba Investments

Jumpcode Genomics develops CRISPRclean, a next-generation sequencing technology that removes abundant, uninformative sequences to improve sensitivity, lower costs, and simplify workflows for researchers.

AI & Machine LearningBiotechDeep TechHealthtechSan Diego, US

David Michael Salter(Executive Officer, Director)Mike Salter(CEO/President)inEugene Chen(Director)Keith Brown(Executive Officer, Director)Joel Rotroff(Director)

BoardCourt Turner(Director)

Co-investorsLYLYZZ Capital

Nashville, US

LFLance Fusacchia(Executive Officer)inThomas Cox(Executive Officer, Director)SBSusan Brownie(Executive Officer)in

BoardJay C. Mason(Director)Timothy Petersen(Director)DJDavid Jones, Jr.(Director)in

Co-investorsCHChrysalis Ventures

HealthStream's Nursegrid Unlimited CE is a subscription service offering nurses unlimited access to continuing education courses that meet state-specific regulatory requirements for nursing practice compliance.

ConsumerDigital HealthEdTechFuture of WorkHealthtechHR TechSaaS

Co-investorsEXExcelerate Health VenturesHAHatteras Venture PartnersPOPortland Seed FundTOToba Capital

Pharaoh Neuro is a neurotechnology company focused on protecting and restoring brain health, with an emphasis on the fluids surrounding the brain such as cerebrospinal fluid.

BiotechDeep TechHealthtechMedical Devices

Mark Wagner(Founder, Investor, & Director in Pharaoh)inDr. Nandan Lad(Chief Medical Officer & Co-Founder)Rich Nazarian(Founder, Investor, & Director in Pharaoh)inARAmaza Reitmeier(Chief Executive Officer, Director)in

Co-investorsHAHatteras Venture PartnersIAIAG Capital PartnersLALaerdal Million Lives Fund

Uptake Medical is a medical device company developing Bronchoscopic Thermal Vapor Ablation, a non-surgical, non-implant therapy that applies heated water vapor to ablate diseased lung tissue.

BiotechHealthtechMedical DevicesTustin, US

Robert Barry(Executive Officer, Promoter)Krista Mann(Executive Officer)R. King Nelson(Executive Officer, Director)in

BoardCarl Simpson(Director)DSDavid Singer(Director)inGeoff Brooke(Director)

Co-investorsMAMaverick Ventures

ViaLase develops the ViaLase Laser System, a femtosecond laser and HD imaging platform for noninvasive interventional glaucoma treatment that creates apertures through the trabecular meshwork in patients with open-angle glaucoma.

Deep TechHealthtechMedical DevicesAliso Viejo, US

TJTibor Juhasz(Executive Officer, Director)inRLRick Lewis(Executive Officer)SCScott Cooper(Executive Officer)HSHadi Srass(Executive Officer)inSOShawn O'Neil(Executive Officer)in

BoardWilliam Link(Director)

Co-investorsVEVersant Venture AIV Holdings