Ysios Capital — Full Portfolio

CVRx develops Barostim, an implantable medical device that uses baroreceptor activation to treat heart failure patients and improve their functional capacity and quality of life.

BiotechHealthtechMedical DevicesAustin, US

CPCraig Palmer(Executive Officer)inNadim Yared(Executive Officer, Director)inDean Bruhn-Ding(Executive Officer)inJohn Brintnall(Executive Officer)inLiz Galle(Executive Officer)KHKevin Hykes(President, Chief Executive Officer & Director)in

Co-investorsNENew Enterprise Associates (NEA)TRTreo Ventures, LlcWIWindham Capital PartnersHAHatteras Venture PartnersVEVensana Capital

A biopharmaceutical company developing an artificial intelligence infrastructure platform designed for on-premises deployment in biotechnology and pharmaceutical research environments, serving biotech firms and pharma companies seeking secure access to advanced AI capabilities while retaining control over proprietary biological data; the company is also evaluating strategic alternatives for its legacy mesenchymal stem cell secretome assets after discontinuing its lead rare eye disease therapeutic program.

BiotechArlington, US

Justin Hanes(Director)Kevin Pojasek(Executive Officer)Darius Kharabi(Executive Officer)TBTodd Bazemore(Executive Officer)inMIMark Iwicki(Executive Officer, Director)inMary Reumuth(Executive Officer)

Co-investorsLOLongitude CapitalSRSR One Capital ManagementATAtlas VentureLULux CapitalRARA CapitalTHThird Rock Ventures

Mineralys Therapeutics is a clinical-stage pharmaceutical company developing lorundrostat, a treatment targeting dysregulated aldosterone.

BiotechHealthtechRadnor, US

Eric Warren(Chief Commercial Officer)inAGAlex Gold(Chief Medical Officer)inAdam Levy(Executive Officer)Alexander Asam(Director)

BoardBrian Taylor Slingsby(Founder & former CEO / Board Director)OLOlivier Litzka(Director)in

Co-investorsANAndera PartnersSASamsara BioCapitalSRSR One Capital ManagementADAdams Street PartnersBOBoulder VenturesCACatalys Pacific+1 more

Engrail Therapeutics is a clinical-stage pharmaceutical company developing precision-targeted therapeutics for neupropsychiatric and neurodevelopmental disorders.

BiotechDigital HealthMedical DevicesSan Diego, US

Stephen(Co-founder, EVP Research & Development and Chief Development Officer)Paul Cayer(Chief Financial Officer)inVikram(President and Chief Executive Officer)Kimberly(Chief Scientific Officer)Quentin(Chief Technical Officer)

Co-investorsFOForesite CapitalLOLongwood FundNONorwest Venture PartnersRIRiverVest Venture PartnersABabrdn plcEIEight Roads Ventures+4 more

Kynexis is a clinical-stage biotech developing KYN-5356, an oral small-molecule KAT-II inhibitor targeting the kynurenine pathway to improve cognition in neurological diseases.

BiotechDeep TechHealthtech

Robert Schwarcz(Scientific Co-founder)Carol Tamminga(Scientific Co-founder & Chair of the SAB)Christer Köhler(Founding Director)inKees Been(Chief Executive Officer)inJens Wendland(Chief Medical Officer)inNeil Swami(Chief Business Officer)

Co-investorsFOForbionNONovartis Venture FundSUSunstone Capital

Memo Therapeutics develops therapeutic antibodies targeting viral infections to improve treatment outcomes for patients with conditions like BKPyV infection in kidney transplant recipients and oncological viral diseases.

BiotechMedical DevicesZurich, CH

Co-investorsKUKurma PartnersPUPureos BioventuresADAdjuvant CapitalFRFresenius Medical Care VenturesVEVerve VenturesREredalpine

NorthSea Therapeutics is a clinical-stage biopharmaceutical company developing oral fatty acid-derived therapies for liver and metabolic diseases, including intestinal failure-associated liver disease (IFALD), severe hypertriglyceridemia, and MASH.

BiotechDigital HealthHealthtech

Co-investorsNENew Science VenturesVEvenBio PartnersBGBGVNONovo HoldingsSOSofinnova Ventures

SpliceBio develops genetic medicines using a proprietary protein splicing platform to treat diseases caused by mutations in large genes.

BiotechDeep TechDigital HealthBarcelona, ES

Dr. Vila-Perelló(CEO)Dr. Frutos(Co-founder)

Co-investorsNONovartis Venture FundRORoche Venture FundSASanofi VenturesASAsabys PartnersCRCriteria Bio VenturesNENew Enterprise Associates (NEA)+2 more

Synendos is a biotech company developing selective endocannabinoid reuptake inhibitors targeting the endocannabinoid system to treat neuropsychiatric disorders.

BiotechDeep TechDigital HealthMental HealthBasel, CH

Prof. Jürg Gertsch(Founder)Dr. Andrea Chicca(Co-Founder & Chief Executive Officer)Dr. Simon Russell(Co-Founder & Chief Commercial Officer)

Co-investorsKUKurma PartnersSUSunstone Capital

VarmX develops VMX-C001, a therapeutic medicine for treating severe bleeding in patients on Factor Xa anticoagulants and for emergency surgery settings.

BiotechHealthtechMedical Devices

Pieter ReitsmainJGJohn Glasspool(Chief Executive Officer)in

Co-investorsSOSound BioventuresBIBioGeneration VenturesEIEICEQEQT Life SciencesINInkefUNUNIIQ+2 more

Vivet Therapeutics is a clinical-stage biotechnology company developing recombinant adeno-associated virus (rAAV) gene therapies for rare, inherited metabolic diseases, including Wilson's Disease and cerebrotendinous xanthomatosis.

BiotechHealthtechParis, FR

Co-investorsHEHealthCapKUKurma PartnersNONovartis Venture FundRORoche Venture FundCOColumbus Venture PartnersEUEurazeo+1 more

Adcendo develops antibody-drug conjugates (ADCs) engineered to treat cancers with high unmet medical needs.

BiotechDigital HealthMedical Devices

Co-investorsVIVida VenturesJEJeito Capital

AELIX Therapeutics is a company developing a therapeutic HIV vaccine intended for use in HIV cure and eradication strategies.

BiotechHealthtechBarcelona, ES

Co-investorsCRCriteria Bio Ventures

AM-Pharma develops ilofotase alfa, a recombinant alkaline phosphatase enzyme therapy, and is studying it as a treatment for adults with hypophosphatasia (HPP), a rare inherited metabolic bone disease.

BiotechHealthtech

Co-investorsANAndera PartnersKUKurma Partners

Anaconda Biomed develops next-generation endovascular access and protection devices.

BiotechHardwareHealthtechMedical DevicesBarcelona, ES

Trent Reutiman(CEO)inHendrik Lambert(Vice-President of Clinical & Regulatory Affairs)inDr. Iñaki GalveJordi Cardonain

BoardMaria Jose Alonso

Co-investorsASAsabys PartnersEUEuropean Investment BankINInnogest Capital

Babyscripts provides a maternity care platform with remote patient monitoring, risk screening, and care management services for pregnant and postpartum patients.

Digital HealthFemTechHealthtech

JPJuan Pablo Segura(Founder)inASAnish Sebastian(Founder & CEO)in

Co-investorsCUCU Healthcare Innovation FundMEMemorialCare Innovation FundPHPhilips VenturesBUBuilders + BackersCICivilization Ventures Management, LlcIRIrishAngels+4 more

Babyscripts offers remote patient monitoring and care management tools for maternal health, serving health systems, private practices, and payers to identify clinical and social risks during pregnancy and postpartum periods.

Digital HealthFemTechHealthtechSaaS

Co-investorsAAAAF Management Ltd.CUCU Healthcare Innovation FundIRIrishAngels

BiotechSan Leandro, US

SASteve Abella(Chief Medical Officer)inGraeme Currie(Chief Operating Officer)inSWStephen W. Lau(President, Chief Executive Officer, and Treasurer)inKenneth Schwartz(Executive Officer)inEYEric Yuen(Executive Officer)inMarten Steen(Director)in

Co-investorsHEHealthCapINInkefSESectoral Asset ManagementSOSofinnova Ventures

Amgen is a biopharmaceutical company that develops and manufactures therapeutics targeting oncology, cardiovascular disease, inflammation, bone health, neuroscience, and other serious illnesses.

BiotechDigital HealthHealthtechMedical DevicesThousand Oaks, US

George B. Rathmann(First CEO)

BoardWilliam K. Bowes

Co-investorsASAsset Management CompanyBOBOMCWCWRU Technology VenturesMAMayfield FundUSUS Venture Partners

Ipsen is a biopharmaceutical group that publishes financial, legal, and non-financial reporting for shareholders, investors, and the public through documents such as its Universal Registration Document.

BiotechHealthtech

Co-investorsNENew Enterprise Associates (NEA)

CorWave produces a ventricular assist pump for advanced heart failure patients, delivering pulsatile flow to provide mechanical cardiac support for transplant candidates, non-transplant-eligible patients, and recovery cases.

BiotechDeep TechHealthtechMedical Devices

Louis de Lillers(CEO)inAndreas Fleischli(CTO)in

Co-investorsSOSofinnova Partners

Cytoki is a biotech company developing IL-22-based therapeutics using lipidation technology to treat metabolic diseases such as obesity and type 2 diabetes, as well as conditions involving epithelial injury like inflammatory bowel disease.

BiotechHealthtechVærløse, DK

Rasmus Jorgensen(CEO & Founder)

Co-investors+N+ND CapitalSESeventure Partners

Abbott's cardiovascular division provides cardiac and vascular medical devices and technologies, including electrophysiology products for treating conditions such as AFib and remote hemodynamic monitoring for heart failure.

HealthtechMedical Devices

Co-investorsANAndera Partners

Fusion Pharma develops targeted alpha therapeutics that link alpha-emitting medical isotopes to molecules targeting biomarkers on cancer cell surfaces to selectively kill tumor cells.

BiotechHealthtech

Co-investorsFAFACIT (Fight Against Cancer Innovation Trust)HEHealthCapLULumira VenturesSESeroba Life SciencesVEVenture OntarioADAdams Street Partners+2 more

Damora Therapeutics is a biotechnology company developing subcutaneous biologics as targeted, disease-modifying treatments for patients with mutant calreticulin (mutCALR)-driven myeloproliferative neoplasms such as essential thrombocythemia and myelofibrosis.

BiotechMedical Devices

JJJennifer Jarrett(Chief Executive Officer & Board Director)inSSSherwin Sattarzadeh(Chief Operating Officer)inBHBecker Hewes(Chief Medical Officer)GWGarrett Winslow(General Counsel)inJBJim Baker(Chief Corporate Affairs Officer)inBBBrian Burkavage(Senior Vice President, Finance)in

Co-investorsEIEIR VenturesHAHadean VenturesM M VenturesSESEED Capital DenmarkSUSunstone CapitalMAMaverick Ventures+1 more

InBioMotion offers a biomarker test that analyzes MAF gene levels to assess prognosis and guide personalized bisphosphonate treatment in early breast cancer patients.

BiotechDigital HealthMedical Devices

BoardProf Rob E. Coleman(Chairman)

Co-investorsCRCriteria Bio VenturesALAlta Life SciencesASAsabys Partners

The National Kidney Foundation works to eliminate preventable kidney disease, accelerate innovation in patient care, and address structural inequities in kidney treatment and transplantation services.

HealthtechImpact & Social Good

Co-investorsBIBioGeneration VenturesEPEpidarex CapitalRORoche Venture FundSCScottish National Investment BankSOSofinnova Partners

LAVA develops the Gammabody platform, which generates bispecific antibodies that activate gamma-delta T cells to treat cancer by directing immune cells to tumors and triggering anti-cancer immune responses.

AI & Machine LearningBiotechHealthtechMedical Devices

Ton AdanginHans van der Vliet(Head of Innovation)inSHSteve Hurly(Chief Executive Officer)Oxana Polyakova(Chief Scientific Officer)in

Co-investorsMRMRL Ventures FundSASanofi VenturesGIGilde HealthcareREREDMILE

Minoryx is a registration-stage biotech company developing novel therapies for severe, orphan genetic diseases of the central nervous system, with a lead compound (leriglitazone) in clinical trials for conditions including cerebral adrenoleukodystrophy, Friedreich's Ataxia, and Rett syndrome.

BiotechDeep TechHealthtechMedical DevicesMataró, ES

MMMarc Martinell(Co-Founder & Chief Executive Officer)in

Co-investorsCHChiesi VenturesCRCriteria Bio VenturesFUFund+INInvivo Capital PartnersKUKurma PartnersRORoche Venture Fund+1 more

ClinicalTrials.gov is a public registry and results database of clinical studies conducted around the world, maintained by the U.S.

Digital HealthHealthtech

Co-investorsADAdvent Life Sciences

Neurona Therapeutics is a clinical-stage biotherapeutics company developing allogeneic neural cell therapies to treat chronic disorders of the nervous system.

BiotechDeep TechHealthtechSouth San Francisco, US

CNCory Nicholas(Executive Officer, Director, Promoter)inJSJames Stutz(Chief Financial Officer and Chief Business Officer)inCPCatherine Priest(Chief Development Officer)inGautam Banik(Chief Technology Officer)inEduardo Dunayevich(Chief Medical Officer)inArnold Kriegstein(Director)

Co-investorsBEBerkeley FrontierIAIaso VenturesTHThe Column GroupALAlexandriaFIFidelity InvestmentsLYLYFE Capital+7 more

Ona provides cloud-based agent infrastructure that runs developer tasks in isolated environments while laptops are closed, automating workflow execution through events, schedules, and pull requests.

AI & Machine LearningCloud ComputingDeveloper Tools

Co-investorsBRBright Pixel CapitalCRCrane Venture PartnersPEPebblebedPRPreston-Werner VenturesALAlta Life SciencesASAsabys Partners+4 more

WE ARE ONA is a creative culinary studio that designs bespoke dining experiences for luxury and artistic brands, combining strategy, design, and production to reinforce emotional connections between brands and their audiences.

ConsumerFoodTechMarketplacesParis, FR

Luca Pronzato(Founder)

Co-investorsWIWind VentureCOColumbus Venture PartnersKOKorysMÉMérieux Equity Partners

Ona Therapeutics develops therapeutic antibodies targeting lipid metabolism to treat advanced and metastatic cancers, including liposarcoma.

BiotechHealthtechMedical Devices

Co-investorsFUFund+KOKorysMÉMérieux Equity PartnersALAlta Life SciencesASAsabys PartnersBPBpifrance+2 more

OxThera develops a live biotherapeutic product based on oxalate-degrading bacteria to treat primary hyperoxaluria and other rare kidney diseases.

BiotechHealthtechMedical DevicesStockholm, SE

Elisabeth Lindner(Chief Operating Officer)Mats-Olof Wallin(Chief Financial Officer)Milt Allison

Co-investorsSUSunstone Capital

Prexton Therapeutics was a biopharmaceutical company developing novel therapies for Parkinson's disease, including its lead mGluR4 modulator candidate foliglurax.

BiotechHealthtechMedical DevicesCopenhagen, DK

Co-investorsCACardinal PartnersM M VenturesSESeroba Life SciencesSUSunstone Capital

ReproNovo develops therapeutic solutions for male and female fertility and women's health conditions like adenomyosis, targeting unmet medical needs in reproductive medicine.

BiotechFemTechHealthtechMedical DevicesLausanne, CH

Co-investorsJEJeito CapitalM M Ventures

CSL is a biotechnology company that develops and manufactures plasma-derived and other therapies, including biotherapies for rare and serious diseases, vaccines, and treatments for iron deficiency and kidney disease.

BiotechHealthtechMedical Devices

Joan Perello Bestard(Founder)inCCCris Calsadain

Co-investorsANAndera PartnersCRCriteria Bio VenturesINInvivo Capital Partners

SparingVision develops neuroprotective gene therapies for rare genetic diseases affecting the eye and nervous system.

BiotechDeep TechDigital HealthMedical Devices

Co-investorsADAdBio partnersJEJeito Capital

Qiagen manufactures enzymes and molecular biology products, plus scientific research tools and software for studying biological targets and pathways.

BiotechData & InfrastructureDigital HealthHealthtechMedical Devices

Co-investorsHAHarmonic Growth PartnersPFPfizer Venture Investments

Tagworks Pharmaceuticals develops cancer therapies using its Click-to-Release platform, a chemical reaction that activates antibody-drug conjugates (ADCs), masked immunomodulators, and other prodrugs on-target while deactivating radioimmunotherapies off-target.

BiotechHealthtechMedical DevicesNijmegen, NL

Co-investorsBIBifLILightstone VenturesNENew Enterprise Associates (NEA)NONovartis Venture FundGIGilde HealthcareOOOost NL

Takeda is a global pharmaceutical company that develops medicines and treatments for patients, focused on advancing science, technology, and partnerships to create new standards of care.

BiotechHealthtechTokyo, JP

Claudia D'Augusta(Executive Officer)inEduardo Bravo Fernandez de Araoz(Executive Officer, Director)Marie Paule Richard(Executive Officer)inWilfried Dalemans(Executive Officer)

BoardJune Almenoff(Director)Russell Greig(Director)

Co-investorsKLKleiner PerkinsRHRho VenturesKRKreos Capital

Xeltis develops implantable vascular devices that transform into living tissue using Restorex supramolecular polymer technology.

BiotechDeep TechHealthtechMedical Devices

ESEliane Schutte(Chief Executive Officer)in

Co-investorsKUKurma PartnersVIVI PartnersEQEQT Life SciencesINInvest-NL