LifeArc Ventures — Full Portfolio

Maxion Therapeutics develops protein and antibody therapeutics using its patented KnotBody technology, which fuses cysteine-rich miniproteins (Knottins) into antibody binding loops to target ion channels and GPCRs.

BiotechHealthtechCambridge, GB

JMJohn McCafferty(Co-founder and CTO)inAneesh Karatt-Vellatt(Co-founder and CSO)in

Co-investorsMOMonograph Capital PartnersGEGeneral CatalystSOSolasta Ventures

Affect Therapeutics operates an app-based digital treatment provider offering care for substance use disorders (alcohol, cannabis, opioid) and mental health conditions like depression and anxiety, using methods such as contingency management, CBT, medication-assisted treatment, and peer support.

Digital HealthHealthtechMental HealthNew York, US

JDJeff DeFlavio(Co-founder)inKMKristin Muhlner(Executive Officer, Director)in

BoardKRKevin Ryan(Director)inJRJeff Rinehart(Director)in

Co-investorsARArtis VenturesCICity LightALAlleyCorpKAKapor CapitalSASamsung NextWHWhat If Ventures+1 more

AviadoBio is a gene therapy company developing adeno-associated viral (AAV) treatments for neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

BiotechDeep TechDigital HealthHealthtech

CSChris Shaw(Co-Founder & Chief Scientific and Clinical Advisor)inDYDo Young Lee(Co-Founder)YBYoun Bok Lee(Co-Founder)inLDLisa Deschamps(Chief Executive Officer)inGFGraeme Fielder(Chief Operating Officer)inABAlex Bloom(Chief Development Officer)in

Co-investorsADAdvent Life SciencesDEDementia DiscoveryF-F-Prime CapitalMOMonograph Capital PartnersNENew Enterprise Associates (NEA)

Climb Bio develops monoclonal antibody therapies for immune-mediated diseases, advancing clinical-stage candidates such as budoprutug for conditions including immune thrombocytopenia.

BiotechHealthtech

ABAoife Brennan, MB, ChB(President and Chief Executive Officer)Perrin Wilson, PhD(Chief Business Officer)Susan Altschuller, PhD, MBA(Chief Financial Officer)Edgar Charles, MD(Chief Medical Officer)AJAshley Jones(Senior Vice President, People & Workforce Strategy)inAdam Villa, MBA, MS(Senior Vice President, Technical Operations)

Corteria Pharma develops interceptive therapies aimed at treating subpopulations of patients with heart failure, sarcopenia, and obesity.

BiotechDigital HealthHealthtechLongevity

PJPhilip JaniakinMOMarie-Laure OzouxinRORégis OlivierinFrancesca C. LawsonMark KowalaEJEleonore Jouannyin

Co-investorsFOFountain Healthcare PartnersJEJeito CapitalKUKurma PartnersOROrbiMedV-V-Bio VenturesOMOmnes Capital+1 more

NeuLogiq is a research platform for clinical trials that integrates tablet-based cognitive assessments, EEG monitoring, and real-world behavioral data to measure brain function changes.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesBelfast, GB

BMBrian Murphy(Co-Founder & CSO)inTina(CEO)

Co-investorsDEDementia Discovery FundCLClarendon Fund Managers Ltd.

Cytospire Therapeutics develops multispecific antibodies and next-generation γδ T cell engagers designed to direct innate and adaptive immune effector cells as an alternative to CD3-based engagers.

BiotechHealthtech

Co-investorsCRCriteria Bio VenturesMEMedical Incubator Japan K.K.MOModi VenturesPAPathway BioventuresSOSound Bioventures

Droia Ventures is a specialist venture capital firm investing globally in early-stage drug development companies focused on therapeutics for oncology and genetic disease.

BiotechLeuven, BE

Co-investorsCLClavystBioFRFrazier Life SciencesNONovo Holdings

Exciva is a company focused on neurological and neurodegenerative conditions, led by a team with expertise in chemistry, clinical operations, and regulatory affairs.

BiotechDigital HealthLongevityMedical DevicesHeidelberg, DE

HMHans Moebius(Co-founder and CMO, Head of Clinical Operations)inABAnton Bespalov(Co-founder and CSO, Head of Regulatory Affairs)in

Co-investorsANAndera PartnersFOFountain Healthcare PartnersMOModi Ventures

Extracellular is a biomanufacturing company that helps cell-based product developers in cultivated meat, plant cell culture, and bioactives accelerate discovery, overcome production challenges, and commercialize their products.

Advanced ManufacturingBiotechFoodTechNew Materials

WMWill Milligan(CEO & Founder)in

Co-investorsBIBig Idea VenturesFFFFFNENewland SyndicateUNUnruly Capital5A5AM VenturesAGAgent Capital+8 more

Fluid Biomed develops a bioresorbable polymer-based stent designed to treat brain aneurysms by diverting blood flow and reducing risk of stroke.

BiotechDeep TechHealthtechMedical DevicesCalgary, CA

Dr. John H. Wong(Co-founder & Chief Executive Officer)Dr. Alim P. Mitha(Co-founder, President & Chief Technology Officer)

Co-investorsACAccelerate FundSHShangBay Capital LLCTHThin Air LabsUCUCeed FundsAMAmplitude Venture CapitalIAIAG Capital Partners

GlycoEra develops glycan-based therapeutics, applying glycoengineering technology to create biologic drugs.

BiotechHealthtechNewton, US

Ganesh V. Kaundinya(President & CEO)in

Co-investors5A5AM VenturesCACatalio Capital Management, LPRORoche Venture FundSISixty Degree CapitalSOSofinnova PartnersAGAgent Capital+1 more

Hillstar Bio develops precision immunotherapies for autoimmune diseases, using antibody engineering to selectively deplete pathogenic immune cells while sparing healthy ones.

BiotechHealthtech

Co-investorsDRDroia VenturesFRFrazier Life Sciences

MC Sciences is a biotech company developing first-in-class mast cell therapeutics based on a discovered mast cell receptor, aimed at diseases across immunology, dermatology, respiratory, gastrointestinal, fibrotic and chronic inflammatory conditions such as chronic urticaria, systemic mastocytosis, COPD, asthma and MCAS.

BiotechHealthtech

Gerhard J. Molderings(Founder)WTWolfgang Taumann(CEO & Co-Founder)in

BoardMikael Dolsten(Board Chairman)

Co-investorsROROC Venture Group

Ozlo manufactures sleep wellness products including blackout sleep masks and audio devices designed to improve sleep quality through light and sound control.

ConsumerHardwareWellness & Fitness

Co-investorsARArtis Ventures

Pheno Therapeutics is a clinical-stage biotech company developing GPR17 antagonists that target oligodendrocytes to promote brain repair.

BiotechMedical DevicesEdinburgh, GB

NCNeil Carragher(Founder)in

Co-investorsADAdvent Life Sciences

RQ Bio discovers and develops long-acting monoclonal antibodies (LAAbs) targeting seasonal influenza to provide protection against severe viral disease.

BiotechHealthtech

Co-investorsFRFrazier Life SciencesEQEQT Life SciencesFOForbionOXOxford Science EnterprisesRERed Tree VentureWEWellington Management

T-Cypher Bio develops drugs with curative potential, focusing on antibody development, T cell biology, and TCR discovery.

AI & Machine LearningBiotechDeep Tech

Co-investorsFUFuture Planet CapitalOXOxford Science EnterprisesPEPerivoli Innovations

Tribune Therapeutics is a preclinical biopharmaceutical company developing medicines that target CCN protein family signaling (such as CCN2/CTGF) to block fibrotic pathways.

BiotechHealthtech

OKOle Kaasbøll(Co-founder)

Co-investorsHEHealthCapINIndustrifondenINInnovestor VenturesINInvestinorNONovo Holdings