BioGeneration Ventures — Full Portfolio

Avidicure develops "Actibody", a triple-agonistic antibody platform built on a human IgG scaffold designed to activate the innate and adaptive immune system for treating oncology and autoimmune diseases.

AI & Machine LearningBiotech

RFRobert Friesen(Founder)in

Co-investorsEQEQT Life SciencesBOBOMCUCurie CapitalKUKurma PartnersV-V-Bio Ventures

Azafaros is a clinical-stage biopharmaceutical company developing small-molecule therapies for severe rare genetic metabolic disorders, including GM1/GM2 gangliosidoses, Niemann-Pick type C disease, and other conditions.

BiotechDeep TechHealthtechMedical DevicesLeiden, NL

Hans Aerts(Professor)HOHermen Overkleeft(Professor)Stan van Boeckel(Professor)

Co-investorsBIBioMedPartnersFOForbionJEJeito CapitalPIPictet GroupASAsahi Kasei Corporate Venture CapitalSESeroba Life Sciences

Citryll is a clinical-stage biotech developing CIT-013, an antibody therapy that targets extracellular traps by selectively binding citrullinated histones to both inhibit new trap formation and clear existing ones.

BiotechHealthtechMedical DevicesOss, NL

RCRenato Chirivi(Co-founder (former CSO))in

BoardPaul Peter Tak(Chair of the Board)

Co-investorsPUPureos BioventuresSESeventure PartnersFOForbionJOJohnson & Johnson Innovation – JJDCBOBOMCUCurie Capital+1 more

Cristal Therapeutics develops therapeutics in the life sciences sector.

BiotechDeep TechDigital HealthMedical DevicesUtrecht, NL

DCDr. Cristianne Rijcken(Chief Scientific Officer and Founder)Dr. Joost Holthuis(Co-founder and former CEO)

Co-investorsCHChemelot VenturesTHThuja CapitalBOBOMDRDroia VenturesBRBrightlands Venture Partners

i2020 Accelerator (T123 LLC) is a drug discovery accelerator that de-risks early-stage science and advances drug discovery platforms toward lead and clinical candidate stage within roughly two years, working across therapeutic areas such as oncology, immunology, and infectious diseases.

BiotechDeep TechHealthtechSan Diego, US

Co-investorsTOTorrey Pines InvestmentOROrbiMedBGBGV

RhyGaze develops gene therapies using optogenetic proteins to restore sight in patients with vision loss caused by retinal photoreceptor dysfunction.

BiotechDigital HealthMedical DevicesBasel, CH

BRBotond Roska(Researcher (M.D., Ph.D.))BGBence György(IOB Assistant Professor & Head of Clinical Translation)inKHKatherine High(CEO)in

Co-investorsARARCH Venture PartnersNONovartis Venture FundF-F-Prime CapitalGVGV (Google Ventures)

VarmX develops VMX-C001, a therapeutic medicine for treating severe bleeding in patients on Factor Xa anticoagulants and for emergency surgery settings.

BiotechHealthtechMedical Devices

Pieter Reitsma(Founder)inJGJohn Glasspool(Chief Executive Officer)in

Co-investorsINInkefSOSound BioventuresYSYsios CapitalEIEICEQEQT Life SciencesUNUNIIQ+2 more

Seattle, US

Meininger David(Executive Officer, Director, Promoter)

BoardRURoger Ulrich(Director)Daniel O'Connell(Director)

Board seatEVEdward van Wezel· per SEC Form D · $17.3M raise · filed Apr 2021

Develops novel therapeutics in oncology and autoimmune diseases.

Co-investorsAVAvoro Capital AdvisorsBOBOMFRFrazier Life Sciences

AiDASH uses satellite imagery and AI to help industries become more resilient, efficient, and sustainable.

AI & Machine LearningCleantechClimate TechEnergySaaSSanta Clara, US

AVAbhishek Vinod Singh(Chief Executive Officer)in

Co-investorsG2G2 Venture PartnersNANational Grid PartnersSESE VenturesTHThe Lightsmith GroupUNUnanimous CapitalBEBenhamou Global Ventures

The company develops therapies for people with severe autoimmune diseases.

BiotechHealthtechMedical Devices

Co-investorsAVAvoro Capital AdvisorsHBHBM Healthcare InvestmentsMPMPM BioImpactPMPMVSESeventure PartnersAEAescap Life Sciences+2 more

Brandaris Therapeutics is a translational-stage biotech developing first-in-class and best-in-class small-molecule therapies for neuropsychiatric disorders such as depression and anxiety, using a differentiated approach to receptor pharmacology.

BiotechDeep TechMental HealthLeiden, NL

Carboledger provides compliance automation and AI-powered data validation for sustainability reporting across supply chains, helping companies meet evolving regulations like ISCC PLUS, REDCert, RED III, and CORSIA.

Climate TechEnterprise SoftwareSaaS

Nikha Garg(Founder)in

Co-investorsARArka Venture LabsAVAvaana Capital

CatalYm develops immunotherapies for solid tumors by neutralizing GDF-15, a factor cancer cells use to suppress immune responses and resist treatment.

BiotechDeep TechHealthtechMunich, DE

Jörg Wischhusen(Scientific Co-founder)SCScott Clarke(Chief Executive Officer)inPGPeter Garcia(Chief Financial Officer)SRSujata Rao(Chief Medical Officer)inSRStefan Ries(Chief Scientific Officer and Head of Munich Site)inAGAndrea Goddard(Chief Technical Officer)in

Co-investorsJEJeito CapitalBIBioqube VenturesFOForbionBABayern KapitalCACanaan PartnersCOcoparion+2 more

Complement Therapeutics is a clinical-stage biotechnology company developing gene therapies for complement-mediated diseases, with a lead AAV-based candidate (CTx001) for Geographic Atrophy secondary to Age-related Macular Degeneration.

BiotechDigital HealthHealthtechMedical DevicesMunich, DE

RHRafiq Hasan(CEO and Managing Director)inMAMuhammad Ali Memon(Chief Medical Officer)in

Co-investorsCACambridge Innovation CapitalGIGimvHAHadean VenturesSESeroba Life SciencesBGBGVFOForbion+2 more

VIB is a non-profit research institute focused on strategic basic research in life sciences, operating in partnership with five Flemish universities.

BiotechDeep TechMedical DevicesGhent, BE

JSJan Steyaert(Founder (Scientific))inCVCedric Ververken(CEO)in

Co-investorsCACapricorn Venture PartnersFUFund+PMPMVQUQuest for GrowthV-V-Bio Ventures

Epsilogen develops antibody therapeutics based on the IgE, IgA, and IgG immunoglobulin isotypes for the treatment of cancer, matching each isotype to specific tumor types and combining isotypes into single antibody molecules.

BiotechHealthtech

TWTim Wilson(Chief Executive Officer)Kevin FitzGerald(Chief Scientific Officer)inCristina Oliva(Chief Medical Officer)inNRNick Robbins-Cherry(Chief Financial Officer)inElizabeth Hardaker(Chief Translational Science Officer)

Co-investors3B3B Future Health FundALAlbionVCEPEpidarex CapitalGLGlobal BioAccess FundNONovartis Venture FundUCUCL Technology Fund

Essenvia offers a regulatory information management platform for medical device regulatory affairs teams, automating submissions (including FDA eSTAR), centralizing registrations, and providing AI-driven regulatory intelligence and lifecycle tracking.

AI & Machine LearningMedical DevicesSaaSWoodland Hills, US

Basant Sahoo(Co-founder & CTO)inSMSoumya Mahapatra(Co-founder & CEO)in

Co-investorsARArka Venture LabsCOCore91.vcEXExpert DOJORERebright PartnersBEBenhamou Global VenturesWAWavemaker Three-Sixty Health

Fibrocor Therapeutics is a drug developer building a pipeline of first-in-class therapeutics that target fibroblast activation to treat fibrotic diseases, with an initial focus on the genetic kidney diseases Alport Syndrome and Autosomal Dominant Polycystic Kidney Disease (ADPKD).

BiotechDeep TechHealthtech

FundaMental Pharma is a preclinical biopharmaceutical company developing dual-acting NMDAR modulators for treatment-resistant depression.

BiotechDigital HealthHeidelberg, DE

Co-investorsCOcoparion

Genase Therapeutics is a biotech company developing cancer therapies that target metabolic vulnerabilities in oncogene-addicted cancers.

BiotechHealthtech

The National Kidney Foundation works to eliminate preventable kidney disease, accelerate innovation in patient care, and address structural inequities in kidney treatment and transplantation services.

HealthtechImpact & Social Good

Co-investorsYSYsios CapitalEPEpidarex CapitalRORoche Venture FundSCScottish National Investment BankSOSofinnova Partners

Kivu Bioscience develops antibody-drug conjugate (ADC) therapeutics in clinical development, advancing a pipeline of cancer treatments through strategic partnerships and collaborations.

BiotechDeep TechHealthtechMedical Devices

MTMohit Trikha(CEO)inSRSophia Randolph(Chief Medical Officer)in

Co-investorsBOBOMGIGimvHEHealthCapM M VenturesRERed Tree VentureNONovo Holdings

Lincode builds LIVIS, an AI-based visual inspection system for manufacturing quality control that lets factory teams train and deploy computer vision models for surface defect detection, assembly verification, and anomaly detection through a no-code interface.

Advanced ManufacturingAI & Machine LearningRobotics

RIRajesh Iyengar(CEO)in

Co-investorsALAlumni VenturesARArka Venture LabsAUAugment VenturesBABasecamp FundEXExpert DOJOGEGeek Ventures+4 more

Mellon Medical manufactures a surgical instrument for abdominal wall closure featuring a double-pointed needle, ergonomic jaws, and atraumatic needle-suture combination.

HealthtechMedical DevicesRotterdam, NL

Co-investorsBOBOMTHThuja Capital

Mironid is a drug development company building a pipeline of therapies targeting cAMP-degrading phosphodiesterase enzymes to treat Autosomal Dominant Polycystic Kidney Disease (ADPKD) and other rare kidney diseases.

BiotechMedical Devices

ARAdele Rowley(Chief Scientific Officer)in

Co-investorsEPEpidarex CapitalRORoche Venture FundSOSofinnova PartnersSCScottish National Investment Bank

NewAmsterdam Pharma develops innovative therapies for cardiovascular disease and lipid-related conditions.

BiotechHealthtechMedical Devices

Co-investorsBABain Capital Life SciencesEQEQT Life SciencesFRFrazier Life SciencesFOForbion

NorthSea Therapeutics is a clinical-stage biopharmaceutical company developing oral fatty acid-derived therapies for liver and metabolic diseases, including intestinal failure-associated liver disease (IFALD), severe hypertriglyceridemia, and MASH.

BiotechDigital HealthHealthtech

Co-investorsNENew Science VenturesVEvenBio PartnersYSYsios CapitalBGBGVNONovo HoldingsSOSofinnova Ventures+1 more

Phosphoenix is developing a neuroprosthetic system that restores functional vision in people with profound blindness by directly stimulating the brain's visual pathway, targeting the lateral geniculate nucleus.

BiotechDeep TechMedical Devices

Pipeshift provides managed inference infrastructure for deploying and scaling AI models with low latency and high reliability.

AI & Machine LearningCloud ComputingData & InfrastructureEnterprise SoftwareSan Francisco, US

ACArko C(CEO)inEFEnrique Ferrao(CTO)inPRPranav Reddy(CIO)inArko Chattopadhyay(Founder)

Co-investorsARArka Venture LabsGOGood News VenturesMYMyAsiaVCSESenseAI VenturesSTStrategxy Ventures LLCY Y Combinator+4 more

River Biomedics develops human cardiac in vitro models used for drug target and compound validation, building a pipeline of cardiac therapies.

BiotechHealthtechMedical Devices

RPRobert Passier(Founder)in

Co-investorsKIKIKK CapitalBGBGVOOOost NL

Scenic Biotech develops modifier therapy, a genetic medicine approach that targets secondary functions in the genome to neutralize the impact of disease-causing mutations.

AI & Machine LearningBiotechDeep TechDigital HealthHealthtech

Co-investorsBIBioMedPartnersEIEIR VenturesINInkefOXOxford Science Enterprises

Soteria Biotherapeutics develops protein-based biotherapeutics and small molecules using its LITE Switch technology platform for drug discovery and development across oncology, immune-oncology, and inflammatory disease indications.

BiotechDeep TechHealthtechMedical DevicesWellness & FitnessSan Francisco, US

Jim Wells(Co-founder, Scientific Advisory Board Chair)KMKristine M Ball(Executive Officer, Director)inZHZachary Hill(Executive Officer, Director)in

BoardNisha Marathe(Director)DADavid Allison(Director)inKGKeno Gutierrez(Director)in

Co-investors5A5AM VenturesNONovartis Venture FundRORoche Venture FundVEVersant VenturesWEWestlake Village BioPartners

STANT b.v. develops small-molecule STING pathway antagonists with a differentiated mechanism of action, targeting autoimmune, inflammatory, cardiovascular, metabolic and neurodegenerative diseases such as systemic lupus erythematosus, ALS, Parkinson's and chronic kidney disease.

BiotechDeep TechHealthtechOss, NL

Søren R. PaludanSonia Assil

Synaffix develops antibody-drug conjugate (ADC) technology, providing linker-payload platforms that attach small-molecule, peptide, and protein-based payloads to antibodies for use in targeted cancer therapies.

BiotechDeep TechHealthtech

Co-investorsBOBOMM M Ventures

TargED is a biopharmaceutical company developing therapeutics for thrombotic disorders, spun out from University Medical Center Utrecht.

BiotechMedical DevicesUtrecht, NL

CMCoen Maas(Co-founder)inSDSteven de Maat(Chief Scientific Officer)inMarc van Moorsel(Director of Operations)inKVKristof Vercruysse(Chief Executive Officer)inRDRob Dekker(Vice President CMC)inFilip Van den Wyngaert(Vice President Asset Management)in

Co-investorsANAndera PartnersCUCurie CapitalFUFund+HAHadean VenturesINInkefRORotrip+1 more

Tessellate Bio is a biotech company researching synthetic lethal interactions beyond Homologous Recombination Deficiency (HRD) to build a pipeline of first-in-class precision medicines.

BiotechHealthtech

Co-investorsBGBGVFOForbion

Tigatx develops engineered IgA antibodies designed to engage neutrophils as a cancer treatment approach.

Biotech

Co-investorsCICivilization Ventures Management, Llc

Totango offers a customer success platform for businesses to manage customer relationships and drive revenue retention and growth, including AI-powered features like account summaries and a customer intelligence engine.

AI & Machine LearningEnterprise SoftwareSaaSSales TechSan Mateo, US

GNGuy Nirpaz(Founder)inTMTomer Manor(VP Finance)inKFKeith Frankel(CEO)inSCSherman Chu(Director)inTomas Carlos Tovar(Director)NJNechemia Jacob Peres(Director)

Co-investorsGRGreat Hill PartnersBEBenhamou Global VenturesCACanvas VenturesGAGarage CapitalBGBGVGEGemini Israel Ventures+1 more

Trainn is a learning management system (LMS) platform that combines video creation, guide authoring, and course delivery in a single interface designed for enterprises and startups.

AI & Machine LearningEdTechEnterprise SoftwareMarketing TechSaaSChennai, IN

VivekSumana

Co-investorsARArka Venture LabsSPSpeciale Invest

XS Innovations develops medical devices for vascular access in hemodialysis patients.

BiotechHealthtechMedical Devices

TSToon Stilma(Co-founder & CEO)JRJoris Rotmans(Co-founder & CSO (Nephrologist))KVKoen van der Bogt(Co-founder & CMO (Vascular and transplant surgeon))RDRuairi Duffy(CTO)

Co-investorsUNUNIIQ