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FinalDose

YC X26

London, GB · Founded 2025 · 5 employees · 4 known investors

FinalDose develops a programmable DNA-targeting molecule designed to recognize and destroy cells carrying specific genetic sequences, with initial applications in oncology across cancer types.

Founders & leadership· Y Combinator alumni (X26)

FinalDose was founded in 2025 by Li-Yao Huang, Steven Lin, and Jeff Liu.

LHLi-Yao Huang
Li-Yao HuanginCo-founder · Chief Scientific OfficerLi-Yao Huang holds a DPhil in Biochemistry from Oxford and conducted postdoctoral research at the MRC Weatherall Institute of Molecular Medicine, where he led CRISPR screening projects focused on cancer drug targets. He now leads FinalDose, a YC-backed company working on BRCA1-deficient cancers and PARP inhibitor resistance mechanisms.
SLSteven Lin
Steven LininFounderHe holds a doctorate in computational biology from Oxford and previously served as data lead at Gutsee Biotech, where he developed machine learning approaches for identifying genetic targets related to viral drug resistance, including work on human genetic susceptibility to infection during the COVID-19 pandemic.
JLJeff Liu
Jeff LiuinFounderJeff Liu holds a PhD in oncology from Oxford and previously founded Vivid Dx, which developed a diagnostic approach for sepsis that reduced testing time from five days to thirty minutes. He is now CEO of FinalDose, a YC-backed company.

Investors · 4

Companies House · registry record

View on Companies House ↗
Registered name
FINALDOSE LTD
Company number
16816175
Status
Active
Company type
Private limited company
Incorporated
28 Oct 2025
Registered office
3rd Floor 1 Ashley Road, Altrincham, Cheshire, WA14 2DT
Nature of business (SIC)
72110 — Research and experimental development on biotechnology
Accounts
next due 28 Jul 2027
Confirmation statement
next due 10 Nov 2026

Current officers · 1

  • Shang-Kuan Lin director, appointed 28 Oct 2025

Source: Companies House public register · retrieved 24 Jul 2026. Contains public sector information licensed under the Open Government Licence v3.0.

In the news

Frequently asked questions

What does FinalDose do?
FinalDose develops a programmable DNA-targeting molecule designed to recognize and destroy cells carrying specific genetic sequences, with initial applications in oncology across cancer types.
Who founded FinalDose?
FinalDose was founded by Li-Yao Huang, Steven Lin, Jeff Liu in 2025.
Who are FinalDose's investors?
FinalDose's investors include Lobster Capital, Scribble Ventures, Y Combinator, ZAKA VC.
Where is FinalDose headquartered?
FinalDose is headquartered in London, GB.