FinalDose
YC X26London, GB · Founded 2025 · 5 employees · 4 known investors
FinalDose develops a programmable DNA-targeting molecule designed to recognize and destroy cells carrying specific genetic sequences, with initial applications in oncology across cancer types.
AI & Machine LearningBiotechHealthtechArtificial IntelligenceGene TherapyTherapeuticsGenetic EngineeringUnited KingdomEurope
Founders & leadership· Y Combinator alumni (X26)
FinalDose was founded in 2025 by Li-Yao Huang, Steven Lin, and Jeff Liu.
LH
Li-Yao HuanginCo-founder · Chief Scientific OfficerLi-Yao Huang holds a DPhil in Biochemistry from Oxford and conducted postdoctoral research at the MRC Weatherall Institute of Molecular Medicine, where he led CRISPR screening projects focused on cancer drug targets. He now leads FinalDose, a YC-backed company working on BRCA1-deficient cancers and PARP inhibitor resistance mechanisms.
SL
Steven LininFounderHe holds a doctorate in computational biology from Oxford and previously served as data lead at Gutsee Biotech, where he developed machine learning approaches for identifying genetic targets related to viral drug resistance, including work on human genetic susceptibility to infection during the COVID-19 pandemic.
Investors · 4
Companies House · registry record
View on Companies House ↗- Registered name
- FINALDOSE LTD
- Company number
- 16816175
- Status
- Active
- Company type
- Private limited company
- Incorporated
- 28 Oct 2025
- Registered office
- 3rd Floor 1 Ashley Road, Altrincham, Cheshire, WA14 2DT
- Nature of business (SIC)
- 72110 — Research and experimental development on biotechnology
- Accounts
- next due 28 Jul 2027
- Confirmation statement
- next due 10 Nov 2026
Current officers · 1
- Shang-Kuan Lin — director, appointed 28 Oct 2025
Source: Companies House public register · retrieved 24 Jul 2026. Contains public sector information licensed under the Open Government Licence v3.0.
In the news
Frequently asked questions
- What does FinalDose do?
- FinalDose develops a programmable DNA-targeting molecule designed to recognize and destroy cells carrying specific genetic sequences, with initial applications in oncology across cancer types.
- Who founded FinalDose?
- FinalDose was founded by Li-Yao Huang, Steven Lin, Jeff Liu in 2025.
- Who are FinalDose's investors?
- FinalDose's investors include Lobster Capital, Scribble Ventures, Y Combinator, ZAKA VC.
- Where is FinalDose headquartered?
- FinalDose is headquartered in London, GB.


