Taiho Ventures, LLC — Full Portfolio

Nextcure is a clinical-stage biopharmaceutical company developing immunotherapies targeting IO pathways, with a focus on oncology applications.

BiotechBeltsville, US

Timothy Mayer(Executive Officer)Michael Richman(Executive Officer, Director)Elaine V. Jones(Director)Udayan Guha(Executive Officer)Anne Borgman(Director)Steven P. Cobourn(Executive Officer)

Anavo Therapeutics is a biopharmaceutical company using its IGNITE platform to develop phosphatase-targeted allosteric modulators, addressing drug targets previously considered undruggable.

BiotechHealthtechLeiden, NL

Birgit Zech(CEO)

Dren Bio is a clinical-stage biopharmaceutical company developing novel antibody therapeutics designed to selectively eliminate pathogenic cells and disease-causing agents, with a pipeline targeting oncology, autoimmune diseases, immunology, and neurology.

BiotechHealthtechMedical DevicesFoster City, US

Nenad Tomasevic(Executive Officer, Director)Ivan Trifunovich(Director)John Wesley(Director)

Board seatSakae Asanuma· per SEC Form D

BiotechBoston, US

Darlene Deptula-Hicks(Executive Officer)Rachel Humphrey(Officer and a Manager)Yunxia Yang(Manager)James Trenkle(Manager)Scott Phillips(Executive Officer)

BoardDavid Parry(Manager)

Board seatSakae Asanuma· per SEC Form D · $75M raise · filed Jan 2025

Breakpoint Therapeutics develops cancer treatments based on modulating DNA damage response pathways.

BiotechMedical Devices

cellvie develops Therapeutic Mitochondria Transplantation, a technique that augments or replaces failing mitochondria to restore cellular energy metabolism, with initial applications in ischemia-reperfusion injury (starting with kidney transplantation) and in mitochondria-enabled gene therapy for the genetic skin disease Epidermolysis Bullosa.

BiotechLongevityMedical Devices

Cullinan Therapeutics develops clinical-stage T cell engager therapies targeting autoimmune diseases and cancer, leveraging immune modulation expertise to advance high-impact therapeutic candidates.

BiotechDigital Health

Epibiologics develops protein degradation medicines using protein sciences and antibody engineering capabilities.

BiotechMedical DevicesSan Mateo, US

Jason Coloma(Director)Ann Lee-Karlon(Executive Officer, Director)Samuel Bjork(Director)Alexandra Cantley(Director)Mitchell Mutz(Executive Officer, Director)Seiji Miyahara(Director)

BiotechMedical DevicesNew Haven, US

Scott Phillips(Executive Officer)Leyi Wang(Manager)Rebecca Frey(Manager)

BoardTim Shannon(Manager)Liam Ratcliffe(Manager)

BiotechSouth San Francisco, US

Jonathan Drachman(Director)Joanne Viney(Director)Joseph Bailes(Director)Ronald Hunt(Director)Andrew Robbins(Director)Mark Chin(Director)

Light Horse Therapeutics is a small molecule drug discovery company that uses proprietary precision gene editing and target-agnostic functional screens to identify functionally critical drug targets and develop small molecule drugs against them.

AI & Machine LearningBiotech

Magnet Biomedicine develops TrueGlue™, a molecular glue discovery platform for designing small molecule therapeutics that induce novel protein-protein interactions to treat cancer and immune disorders.

AI & Machine LearningBiotechMedical Devices

Benjamin F. Cravatt, PhD(Founder & Advisor)David A. Spiegel, MD, PhD(Founder & Advisor)Michael Rosbash, PhD(Founder & Advisor)Richa Saxena, PhD(Founder & Advisor)Stuart Schreiber, PhD(Founder & Advisor)

Normunity develops novel anti-cancer therapies that target interactions between the immune system and tumors to improve drug efficacy and immune response.

Biotech

Orna Therapeutics develops RNA and lipid nanoparticle (LNP) based therapies for treating diseases including oncology and cell therapy applications.

AI & Machine LearningBiotechMedical Devices

Joe Bolen(Chief Executive Officer)Joe Bolen, Ph.D.(Chief Executive Officer)Hope D'Oyley-Gay, JD(Chief Legal Officer)Ciaran Lawlor, Ph.D.(Chief Operating Officer)Frank Neumann, M.D., Ph.D.(Chief Medical Officer)Siva Sakhamuri(Chief Technology Officer)

STORM Therapeutics is a clinical-stage biotechnology company developing small molecule drugs that target RNA modifying enzymes to reprogram cells through RNA biology.

BiotechHealthtechMedical Devices

Theolytics develops oncolytic adenovirus-based immunotherapies to overcome the tumor microenvironment barriers in solid cancers.

BiotechDeep TechMedical Devices

Microfluidics and machine learning platform for discovering modulators of biomolecular condensates.

BiotechCambridge, US

Tuomas Knowles(Director)Samuel Cohen(Director)George Martin(Executive Officer, Director)Stephanie Torruella(Executive Officer)Preet Makkar(Executive Officer)Martin Kulander(Executive Officer)

Vertero is a biotech company developing oral therapeutics that target peripheral drivers of neurodegenerative diseases such as Parkinson's.

BiotechHealthtech

Werewolf Therapeutics is a biotechnology company developing immunotherapy treatments for cancer.

BiotechHealthtechMedical DevicesWatertown, US

Daniel J. Hicklin(Founder, President, Chief Executive Officer, and Board member)Luke Evnin(Co-founder, Board member (Chairman))Daniel Hicklin(Executive Officer, Director)Alon Lazarus(Director)David Cordo(Executive Officer)

BoardChristoph Westphal(Director)

LiberoThera is a drug discovery company using cell-free membrane protein preparation technology and non-natural amino acid incorporation technology to develop antibody-based therapeutics, including antibodies targeting GPCRs such as anti-CCR8.

BiotechDeep Tech