Plum Alley Investments — Full Portfolio

AiFi uses AI and computer vision to make physical spaces searchable, observable, and understandable, providing real-time insights for facility and space operators without manual audits.

AI & Machine LearningEnterprise SoftwareIoTRetail Tech

Steve Gu(Founder & CEO)Ying Zheng(Founder)

Co-investorsAmino CapitalCervinCommunitas Capital PartnersDuke Capital PartnersEvolution VenturesGS Futures+5 more

Co-investorsKapor CapitalFearless FundGingerbread Capital

ARIX combines robotics and data analytics to inspect and manage critical industrial assets.

AI & Machine LearningDeep TechEnergyIoTRoboticsJackson, US

Dianna Liu(President and CEO)in

Co-investorsAlleyCorpContour Venture PartnersDorm RoomEnergy Transition VenturesInnovation Catalystkineo finance+4 more

AVTTX is a clinical-stage company developing gene therapy treatments for retinal and ophthalmologic diseases.

BiotechDigital HealthHealthtechMedical Devices

George Montgomery(Executive Chairman)

Co-investorsEcoR1 CapitalEvolution VC PartnersHelios CapitalSocii CapitalTribe Capital Firstlook

Biobot pioneers wastewater epidemiology, monitoring pathogens and substances in sewage to provide real-time public health surveillance at the community level.

BiotechData & InfrastructureGovTechHealthtechBoston, US

Newsha Ghaeli(Cofounder & President)inMariana Matus(Founder)inMariana Guadalupe Matus Garcia(Executive Officer, Director)

BoardVivek Pattipati(Director)inAndrew Perlman(Director)in

Co-investorsAmerican Family Insurance Institute for Corporate and Social ImpactBlindspot Ventures Management CoDCVC (Data Collective)Dorm RoomHomebrewPathbreaker Ventures+5 more

BioEclipse Therapeutics is a clinical-stage oncology company developing immuno-oncology therapeutics using a proprietary platform that targets the tumor microenvironment through engineered immune cell therapies.

BiotechDigital HealthHealthtechMedical DevicesSouth San Francisco, US

Pamela Reilly Contag(Executive Officer, Director)Catherine Sohn(Director)Gregory Schiffman(Director)Mark Frohlich(Director)Stephen Thau(Executive Officer)Elona Baum(Director)

Co-investorsFoothill Ventures

Cordex Systems develops SmartCuff, a medical device that repurposes blood pressure cuff technology as a linear sensor to detect early warning signs of heart disease.

AI & Machine LearningBiotechHealthtechMedical DevicesAnnapolis, US

Kathy Elizabeth Magliato(Executive Officer, Director, Promoter)Albert Fleury IIIinMichael Whittin

BoardDennis SchmulandinGeorge Abein

Co-investorsGingerbread Capital

Diligent Robotics develops AI-powered robot assistants for healthcare settings, focusing on mobile manipulation and social intelligence to help hospital staff with routine non-patient-facing tasks.

AI & Machine LearningHealthtechMedical DevicesRoboticsAustin, US

Andrea Thomaz(Founder & CEO)Andrea L. Thomaz(Founder)inVivian Chu(Founder)in

BoardQuaeed Motiwala(Director)Rohit Sharma(Director)Lance VandenBrook(Director)

Co-investorsATPCanaan PartnersCorrelation VenturesDnx VenturesGrit VenturesNext Coast Ventures+6 more

Einride develops autonomous electric vehicles and fleet management solutions for decarbonization, serving large enterprises seeking to reduce emissions at scale.

AI & Machine LearningCleantechClimate TechLogistics & Supply ChainMobility & TransportationStockholm, SE

Robert Falck(Founder and Executive Chairman)inLinnéa Kornehed Falck(Co-Founder)inFilip Lilja(Co-Founder)inRoozbeh Charli(CEO)Henrik Green(CTO)

Co-investorsMaersk GrowthNordicNinjaNordicNinjaVCNorthzoneEQT VenturesPlug and Play Ventures+1 more

EpiBone engineers bone tissue from stem cells for regenerative medicine and clinical reconstruction, serving patients requiring bone grafts or craniofacial repair.

BiotechHealthtechMedical DevicesNew York, US

Nina Tandon(Co-Founder, CEO)Sarindr Bhumiratana(Co-Founder)Gordana Vunjak-Novakovic(Director)Elma Hawkins(Director)

BoardRobert Langer(Director)David Zhu(Director)in

Co-investorsBeresford VenturesEMV CapitalHackensack Meridian Health Bear's DenKendall Capital PartnersTachyon VenturesTech Council Ventures

Evrnu develops technology to transform textile waste into recyclable fibers for apparel manufacturing, creating sustainable alternatives to conventional textiles without compromising quality or performance.

Circular EconomyCleantechClimate TechNew MaterialsSeattle, US

Christopher Stanev(Executive Officer, Director)Stacy Flynn(Executive Officer, Director)Christopher Stenev(Executive Officer, Director, Promoter)

BoardCorey Vernon(Director)inKyle Adkins(Director)Julie Guggemos(Director)

Co-investorsMagic HourRadicle Impact

One Health operates a clinical trial platform using canine cancer data to accelerate and de-risk human oncology drug development.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesSan Francisco, US

Christina Lopes(Co-Founder & CEO)inBen Lewis(Co-founder)Benjamin Lewis(Co-Founder)inchristina lopes(Founder)in

Co-investorsAndreessen HorowitzaVentureCivilization Ventures Management, LlcGlobal BrainMaC Venture CapitalMyAsiaVC+5 more

Gameto develops cell therapy and reproductive technologies to treat infertility and improve women's health outcomes.

BiotechFemTechHealthtechMedical DevicesAustin, US

Dina Turner(Co-founder & Chief Executive Officer)inMartin Varsavsky(Co-founder & Chairman)inDina Radenkovic(Executive Officer, Director)

BoardDusan Perovic(Director)inDylan Morris(Director)Maryanna Saenko(Director)in

Co-investorsBold Capital PartnersFuture VenturesIngeborg InvestmentsJazzya InvestmentsKorify CapitalLux Capital+11 more

Helaina uses precision fermentation to produce human proteins, including lactoferrin and other bioactive nutrients found in human milk, for consumer nutrition products serving athletes, new parents, and health-conscious consumers.

AI & Machine LearningBiotechFoodTechHealthtechNew York, US

Laura Katz(Founder & CEO)in

Co-investorsBarrel VenturesCosmic Venture PartnersIngeborg InvestmentsTrousdale VenturesPrimary Venture PartnersSpark Capital

humans& is a frontier AI lab focused on building human-centric AI systems that prioritize people and their relationships, emphasizing innovations in reinforcement learning, memory, and user understanding to create AI that strengthens organizations and communities.

AI & Machine LearningEnterprise SoftwareSaaSEl Segundo, US

Eric Zelikman(Co-founder)Noah Goodman(Founder)inAlaarif Nooruldeen(Executive Officer, Director)

BoardKristen Green(Director)Allen Mask(Director)Jonathan Ellman(Director)

Co-investorsGV (Google Ventures)S32SV AngelNVIDIAA.Capital VenturesChamaeleon+6 more

InnerPlant develops living sensor technology that enables farmers to detect plant stress in real-time, allowing targeted application of treatments to reduce chemical use and increase crop yields.

AgTechBiotechIoTCalifornia, US

RodinShely Aronov(Executive Officer, Director)Gary Schaefer(Chief Commercial Officer)in

Co-investorsBison VenturesCultiv8 Funds ManagementKokopelli CapitalMS&AD VenturesSystemiq CapitalTAU Ventures+3 more

Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.

AI & Machine LearningBiotechLongevityMedical DevicesRedwood City, US

Jeremy O'Connell, PhD(Chief Scientific Officer and Co-Founder)Hanadie Yousef, PhD(Executive Advisor and Co-Founder)Hanadie Yousef(Executive Officer, Director)Jeremy O'Connell(Director)Dr. Hanadie Yousef(Founder)in

BoardBen Hemani(Director)in

Co-investorsBascom VenturesBison VenturesCompoundHarmonix FundHorizons VenturesManta Ray Ventures+3 more

KETOS develops an automated water quality and monitoring platform combining hardware, connectivity, software, and services to test water safety and efficiency for cities and businesses.

AI & Machine LearningCleantechData & InfrastructureEnterprise SoftwareIoTMilpitas, US

Meena Sankaran(Executive Officer, Director)Veery Maxwell(Director)

BoardHeidi Patel(Director)inOllen Douglass(Director)

Co-investorsRethink ImpactBetter Ventures Central LlcMotley Fool VenturesThe Perkins FundAccenture Ventures

Kraus Hamdani Aerospace develops ultra-long-endurance autonomous aircraft and AI-enabled airborne systems that provide persistent connectivity, intelligence, and communications infrastructure for defense and national security missions.

AI & Machine LearningDefense TechHardwareIoTRoboticsReno, US

Fatema Hamdani(Co-Founder, CEO)Stefan Kraus(Co-Founder, CTO)

Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.

BiotechDeep TechMedical DevicesBrisbane, US

Jennifer Doudna(Founder)inTrevor Martin(Co-founder, Chief Executive Officer)inJanice Chen(Co-founder, Chief Scientific Officer & President, Research)inLucas Harrington(Co-founder)inAshley Tehranchi(Executive Officer, Director)

BoardUrshit Parikh(Director)

Co-investors8VCBerkeley FrontierCALIFORNIA INNOVATIONDecheng CapitalForesite CapitalMayfield Fund+9 more

Markable.ai is an all-in-one platform for affiliate creators to monetize content through Amazon, Target, and Walmart deeplinks, featuring automated tools for link management, content boosting, and performance optimization.

AI & Machine LearningCreator EconomyMarketing TechMadison, US

Joy Tang(Executive Officer, Director)inFiona Wang(Executive Officer, Director)

BoardSheng Fu(Director)

Co-investorsArbor VenturesFounderPartnersNOEMIS VenturesHeadline

Openwater develops an imaging platform using two optical modalities designed to diagnose and monitor diseases at the size and cost of a smartphone.

AI & Machine LearningDeep TechHealthtechMedical DevicesSan Francisco, US

Dr. Mary Lou Jepsen(Executive Chairman & Founder)in

Co-investorsAIR CapitalBold Capital PartnersCollaborative FundResolute VenturesUntapped Ventures

Openwater develops miniaturized medical devices that use light, sound, and electromagnetic manipulation to treat diseases including cancers, stroke, and mental illness, operating as a hardware and AI platform for physiological data collection and treatment.

AI & Machine LearningHardwareMedical Devices

Co-investorsExcel Venture ManagementLauder PartnersBold Capital PartnersKhosla VenturesStarlight Ventures

Phoenix Tailings develops clean technology for rare earth element refining in the United States.

Advanced ManufacturingCleantechClimate TechEnergyFintechNew MaterialsBoston, US

Nick Myers(CEO & Co-Founder)Thomas Villalón(CTO & Co-Founder)Anthony Balladon(Chief Commercial Officer & Co-Founder)Michelle Chao(Cofounder)Nicholas Myers(Founder)in

BoardNichola Eliovits(Director)in

Co-investorsBantam GroupBMW i VenturesCoalitionGeodesic CapitalMPowerOlive Tree Capital+9 more

Siren Biotechnology develops next-generation AAV (adeno-associated virus) platforms for gene therapy applications, including gene repair, gene transfer, and gene editing.

BiotechDigital HealthMedical DevicesSan Francisco, US

Dr. Nicole Paulk(CEO, Founder, and President)Nicole Paulk(Executive Officer, Director)Lauren Kelly(Founder)inSharon Tetlow(Director)Brad Allen(Director)

Co-investorsArtis VenturesAvilaCarnrite VenturesCivilization Ventures Management, LlcHAWKTAILNZVC+2 more

ThinkCERCA develops K-12 writing software and curriculum designed to teach critical thinking skills to students through structured literacy instruction.

EdTech

Eileen Murphy

Co-investorsEdovate CapitalGingerbread CapitalImpact Engine

Northampton, US

Brian Fitzgerald(Executive Officer, Director)inMeghan Fitzgerald(Director)

BoardIsabelle Hau(Director)

Co-investorsBlue CollectiveCity LightOutbound VenturesOwl VenturesVista Venture Partners500 Global+5 more

Vyv develops UV-free, chemical-free antimicrobial lighting technology using visible spectrum LEDs that continuously reduce microbial growth in occupied indoor spaces.

CleantechHardwareHealthtech

Colleen Costello(CEO)

Co-investorsAlerion VenturesTamiami AngelTech Square VenturesCiti Ventures