Plum Alley Investments — Full Portfolio

AiFi uses AI and computer vision to make physical spaces searchable, observable, and understandable, providing real-time insights for facility and space operators without manual audits.

AI & Machine LearningEnterprise SoftwareIoTRetail Tech

SGSteve Gu(Founder & CEO)YZYing Zheng(Founder)inJoão Diogo Falcão(CEO)

Co-investorsAMAmino CapitalBRBRC InnovationCECervinCOCommunitas Capital PartnersDUDuke Capital PartnersEVEvolution Ventures+10 more

Air Protein produces protein made from elements in the air through a fermentation-based process, creating a land-independent food ingredient.

BiotechClimate TechFoodTechPleasanton, US

LDLisa Dyson, PhD(Founder)inLisa Dyson(CEO)Ori Sasson(Director)James White(Executive Officer, Director)Joseph Grundfest(Director)Maisie Ganzler(Director)

Co-investorsGVGV (Google Ventures)KAKapor CapitalRARadicle ImpactFEFearless FundGIGingerbread Capital

ARIX combines robotics and data analytics to inspect and manage critical industrial assets.

AI & Machine LearningDeep TechEnergyIoTRoboticsJackson, US

DLDianna Liu(President and CEO)in

Co-investorsALAlleyCorpCOContour Venture PartnersCRCreative Destruction Lab (CDL)DODorm RoomENEnergy Transition VenturesGAGaingels+6 more

AVTTX is a clinical-stage company developing gene therapy treatments for retinal and ophthalmologic diseases.

BiotechDigital HealthHealthtechMedical Devices

GMGeorge Montgomery(Executive Chairman)

Co-investorsECEcoR1 CapitalEVEvolution VC PartnersHEHelios CapitalSASand Hill AngelsTRTransform InvestmentsSOSocii Capital+1 more

Biobot pioneers wastewater epidemiology, monitoring pathogens and substances in sewage to provide real-time public health surveillance at the community level.

BiotechData & InfrastructureGovTechHealthtechBoston, US

NGNewsha Ghaeli(President)inMMMariana Matus(Founder)inMariana Guadalupe Matus Garcia(Executive Officer, Director)Ayo Omojola(Investor)in

BoardVPVivek Pattipati(Director)inAPAndrew Perlman(Director)in

Co-investorsAMAmerican Family Insurance Institute for Corporate and Social ImpactBLBlindspot Ventures Management CoDCDCVC (Data Collective)DEDesignXDODorm RoomHAHalf Court Ventures+22 more

BioEclipse Therapeutics is a clinical-stage oncology company developing immuno-oncology therapeutics using a proprietary platform that targets the tumor microenvironment through engineered immune cell therapies.

BiotechDigital HealthHealthtechMedical DevicesSouth San Francisco, US

PRPamela Reilly Contag(Executive Officer, Director)Catherine Sohn(Director)Gregory Schiffman(Director)Mark Frohlich(Director)Stephen Thau(Executive Officer)Elona Baum(Director)

Co-investorsFOFoothill Ventures

Cordex Systems develops SmartCuff, a medical device that repurposes blood pressure cuff technology as a linear sensor to detect early warning signs of heart disease.

AI & Machine LearningBiotechHealthtechMedical DevicesAnnapolis, US

Kathy Elizabeth Magliato(Founder, CEO, CMO)AFAlbert Fleury IIIinMWMichael Whitt(Founder and Inventor)in

BoardDSDennis SchmulandinGAGeorge Abein

Co-investorsGIGingerbread Capital

Diligent Robotics develops AI-powered robot assistants for healthcare settings, focusing on mobile manipulation and social intelligence to help hospital staff with routine non-patient-facing tasks.

AI & Machine LearningHealthtechMedical DevicesRoboticsAustin, US

ALAndrea L. Thomaz(Founder)inVCVivian Chu(Founder)inAndrea Thomaz(Founder)

BoardQuaeed Motiwala(Director)RSRohit Sharma(Director)inLance VandenBrook(Director)

Co-investorsATATPCACanaan PartnersCOCorrelation VenturesDNDnx VenturesGAGaingelsGRGrit Ventures+12 more

Einride develops autonomous electric vehicles and fleet management solutions for decarbonization, serving large enterprises seeking to reduce emissions at scale.

AI & Machine LearningCleantechClimate TechLogistics & Supply ChainMobility & TransportationStockholm, SE

RFRobert Falck(Founder)inLKLinnéa Kornehed Falck(Co-Founder)inFLFilip Lilja(Founder)inRCRoozbeh Charli(Chief Executive Officer)inHGHenrik Green(CTO)inLinnéa Kornehed(Founder)

Co-investorsMAMaersk GrowthNONordicNinjaNONordicNinjaVCNONorthzonePLPlug and Play VenturesWOWolfswood Partners+4 more

EpiBone engineers bone tissue from stem cells for regenerative medicine and clinical reconstruction, serving patients requiring bone grafts or craniofacial repair.

BiotechHealthtechMedical DevicesNew York, US

NTNina Tandon(Co-Founder, CEO)inSBSarindr Bhumiratana(Co-Founder)inGVGordana Vunjak-Novakovic(Director)Elma Hawkins(Director)

BoardRLRobert Langer(Director)DZDavid Zhu(Director)in

Co-investorsBEBeresford VenturesCACatalytic Impact FoundationEMEMV CapitalHAHackensack Meridian Health Bear's DenKEKendall Capital PartnersLILifespan Vision Ventures+3 more

Evrnu develops technology to transform textile waste into recyclable fibers for apparel manufacturing, creating sustainable alternatives to conventional textiles without compromising quality or performance.

Circular EconomyCleantechClimate TechNew MaterialsSeattle, US

Christopher Stanev(Executive Officer, Director)inSFStacy Flynn(Executive Officer, Director)inChristopher Stenev(Executive Officer, Director, Promoter)

BoardCVCorey Vernon(Director)inKyle Adkins(Director)Julie Guggemos(Director)

Co-investorsE8E8 AngelsGOGotham Gal VenturesMAMagic HourRARadicle ImpactFOFor Good VenturesGIGiant Leap+1 more

One Health operates a clinical trial platform using canine cancer data to accelerate and de-risk human oncology drug development.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesSan Francisco, US

CLChristina Lopes(Founder)inBLBenjamin Lewis(COO)inCLchristina lopesinPedro Carrasco(Chief of Staff)Christi Miller(Head of Operations)

Co-investorsANAndreessen HorowitzAVaVentureCICivilization Ventures Management, LlcGAGaingelsGLGlobal BrainIKIKJ Capital+16 more

Gameto develops cell therapy and reproductive technologies to treat infertility and improve women's health outcomes.

BiotechFemTechHealthtechMedical DevicesAustin, US

DTDina Turner(Co-founder & Chief Executive Officer)inMVMartin Varsavsky(Co-founder & Chairman)inDRDina Radenkovic(Founder)inMartín Varsavsky(Founder)

BoardDPDusan Perovic(Director)inDMDylan Morris(Director)in

Co-investorsBOBold Capital PartnersDEDeviation CapitalFJFJ LabsFUFuture VenturesGAGaingelsINIngeborg Investments+19 more

Helaina uses precision fermentation to produce human proteins, including lactoferrin and other bioactive nutrients found in human milk, for consumer nutrition products serving athletes, new parents, and health-conscious consumers.

AI & Machine LearningBiotechFoodTechHealthtechNew York, US

LKLaura Katz(Founder)in

Co-investorsBABarrel VenturesCOCosmic Venture PartnersINIngeborg InvestmentsPRPrimary Venture PartnersTRTrousdale VenturesVIVisible Ventures+4 more

humans& is a frontier AI lab focused on building human-centric AI systems that prioritize people and their relationships, emphasizing innovations in reinforcement learning, memory, and user understanding to create AI that strengthens organizations and communities.

AI & Machine LearningEnterprise SoftwareSaaSEl Segundo, US

EZEric Zelikman(Founder)inNoah Goodman(Founder)inGeorges Harik(Founder)Alaarif Nooruldeen(Executive Officer, Director)Andi Peng(Founder)Ray Ramadorai(Founder)

Co-investorsGVGV (Google Ventures)S3S32SVSV AngelNVNVIDIAA.A.Capital VenturesALAlumni Ventures+19 more

InnerPlant develops living sensor technology that enables farmers to detect plant stress in real-time, allowing targeted application of treatments to reduce chemical use and increase crop yields.

AgTechAI & Machine LearningBiotechDeep TechIoTRoboticsCalifornia, US

RRodinSAShely Aronov(Executive Officer, Director)inMBMichael Berolzheimer(Founder & Managing Partner)inGSGary Schaefer(Chief Commercial Officer)in

BoardJCJocelyne Cooke(CFO)in

Co-investorsBEBee PartnersBIBison VenturesCUCultiv8 Funds ManagementGAGaingelsKOKokopelli CapitalMSMS&AD Ventures+7 more

Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.

AI & Machine LearningBiotechLongevityMedical DevicesRedwood City, US

JOJeremy O'Connell, PhD(Chief Scientific Officer and Co-Founder)HYHanadie Yousef, PhD(Co-Founder, Director and Executive Advisor)JOJeremy O'Connell(Director)inDHDr. Hanadie Yousef(Founder)inJulie Anne Smith(Chief Executive Officer and Director)in

BoardBHBen Hemani(Director)in

Co-investorsALAlumni VenturesBABascom VenturesBIBison VenturesCOCompoundHAHarmonix FundHOHorizons Ventures+5 more

KETOS develops an automated water quality and monitoring platform combining hardware, connectivity, software, and services to test water safety and efficiency for cities and businesses.

AI & Machine LearningCleantechData & InfrastructureEnterprise SoftwareIoTMilpitas, US

MSMeena Sankaran(Executive Officer, Director)inVeery Maxwell(Director)

BoardHPHeidi Patel(Director)inOllen Douglass(Director)

Co-investorsRERethink ImpactBEBetter Ventures Central LlcMOMotley Fool VenturesPLPlug and Play VenturesTHThe Perkins FundACAccenture Ventures

Kraus Hamdani Aerospace develops ultra-long-endurance autonomous aircraft and AI-enabled airborne systems that provide persistent connectivity, intelligence, and communications infrastructure for defense and national security missions.

AI & Machine LearningDefense TechHardwareIoTRoboticsReno, US

FHFatema Hamdani(Co-Founder, CEO)inSKStefan Kraus(Co-Founder, CTO)in

Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.

BiotechDeep TechMedical DevicesBrisbane, US

JDJennifer Doudna(Founder)inTMTrevor Martin(Founder)inJCJanice Chen(Founder)inLHLucas Harrington(Founder)inATAshley Tehranchi(Founder)in

BoardUrshit Parikh(Director)

Co-investors8V8VCBEBerkeley FrontierCACalifornia Innovation FundDEDecheng CapitalFOForesite CapitalMAMayfield Fund+12 more

Markable.ai is an all-in-one platform for affiliate creators to monetize content through Amazon, Target, and Walmart deeplinks, featuring automated tools for link management, content boosting, and performance optimization.

AI & Machine LearningCreator EconomyMarketing TechMadison, US

JTJoy Tang(Executive Officer, Director)inFiona Wang(Executive Officer, Director)

BoardSheng Fu(Director)

Co-investorsARArbor VenturesFOFounderPartnersFOFoundersX VenturesNONOEMIS VenturesPAPartech VenturesPLPlug and Play Ventures+1 more

Openwater develops an imaging platform using two optical modalities designed to diagnose and monitor diseases at the size and cost of a smartphone.

AI & Machine LearningDeep TechHardwareHealthtechMedical DevicesSan Francisco, US

Dr. Mary Lou Jepsen(Executive Chairman & Founder)in

Co-investorsAIAIR CapitalBOBold Capital PartnersCLCleveland AvenueCOCollaborative FundCOColterEXExcel Venture Management+6 more

OpenWater is a membership-based network for accomplished professionals who want to continue doing meaningful work while maintaining access to peer expertise, mentorship, and professional opportunities.

Future of WorkSaaSSector AgnosticSocialSan Francisco, US

Co-investorsREResolute VenturesLALauder Partners

Phoenix Tailings develops clean technology for rare earth element refining in the United States.

Advanced ManufacturingCleantechClimate TechEnergyFintechNew MaterialsBoston, US

TVThomas Villalón(Chief Technology Officer & Co-Founder)ABAnthony Balladon(Founder)inMCMichelle Chao(Founder)inNMNick Myers(Chief Executive Officer & Co-Founder)inNicholas Myers(Founder)Tomas Villalon(Founder)

Co-investorsBABantam GroupBMBMW i VenturesCOCoalitionENEni NextGAGaingelsGEGeodesic Capital+15 more

Siren Biotechnology develops next-generation AAV (adeno-associated virus) platforms for gene therapy applications, including gene repair, gene transfer, and gene editing.

BiotechDigital HealthMedical DevicesSan Francisco, US

Dr. Nicole Paulk(CEO, Founder, and President)inLKLauren Kelly(Founder)inSharon Tetlow(Director)Brad Allen(Director)

Co-investorsARArtis VenturesAVAvilaCACarnrite VenturesCICivilization Ventures Management, LlcGAGaingelsHAHAWKTAIL+4 more

ThinkCERCA develops K-12 writing software and curriculum designed to teach critical thinking skills to students through structured literacy instruction.

EdTechChicago, US

EMEileen Murphy(Executive Officer, Director)inAbby Ross(Executive Officer)inJoshua Tolman(Executive Officer)

BoardChuck Templeton(Director)

Co-investorsEDEdovate CapitalG2G2T3V FundGAGaingelsGRGreat Oaks Venture CapitalHIHis FundNONovel Capital+4 more

A Korean company operating in cryogenics, materials, and high-voltage fields.

Deep TechHardwareNew MaterialsAnyang, KR

Co-investorsKIKiwoom InvestmentSPSpinLabTATAL Education Group

Northampton, US

BFBrian Fitzgerald(Executive Officer, Director)inMFMeghan Fitzgerald(Director)

BoardIsabelle Hau(Director)

Co-investorsBLBlue CollectiveCICity LightOUOutbound VenturesOWOwl VenturesVIVista Venture Partners50500 Global+5 more

Vyv develops UV-free, chemical-free antimicrobial lighting technology using visible spectrum LEDs that continuously reduce microbial growth in occupied indoor spaces.

CleantechHardwareHealthtech

CCColleen Costello(CEO)in

Co-investorsALAlerion VenturesMOModerne VenturesSOSOSVTATamiami AngelTETech Square VenturesWEWellstar+1 more