National Institutes of Health (NIH) — Full Portfolio

NĒRx Biosciences develops small molecule inhibitors targeting DNA damage sensor proteins for cancer treatment, with initial focus on difficult-to-treat lung and ovarian cancers.

BiotechHealthtechMedical DevicesIndianapolis, US

John J. Turchi(President)inJTJohn Turchi(Co-Founder, President and CSO)inNicholas Ball(CFO)Robert Feltgenin

Co-investorsELElevate VenturesIUIU Ventures

St. Paul, US

KHKarl Holub(Executive Officer, Director)inKKKeith Kallmes(Executive Officer, Director)inKKKevin Kallmes(Executive Officer, Director)in

BoardTPTomas Philipson(Director)inDheerendra Kommala(Director)

Co-investorsGRGreat North VenturesGRGROOVE CAPITALMEMEDA AngelsMEMEDA VenturesPAPasadena AngelsSOSoutheast Minnesota Capital Fund+1 more

Neumedicines is a biotechnology company developing small molecule and biologic drug candidates, with clinical development and regulatory work in the pharmaceutical space.

BiotechHealthtechMedical Devices

Elliot P. Friedman(President & Board Member)Vladimir Vainstein(CMO)Christopher Lawrence(VP, Development)Scott Buckel(VP, CMC Analytical/Regulatory)

NeurAegis is a biotechnology company focused on discovering and developing therapies for neurodegeneration, leveraging research into calpain-2 protease inhibitors.

BiotechHealthtechMedical Devices

Michel Baudry(Founder & Chief Scientific Advisor)Stella M. Sung(President & CEO)

Los Angeles medical device company building transcranial Doppler ultrasound systems to measure, diagnose and track brain health.

HealthtechLos Angleles, US

LPLeo Petrossian(Executive Officer, Director)inMHMark Hattendorf(Executive Officer)in

BoardYuri Pikover(Director)Roy Doumani(Director)Kenneth Baker(Director)Stan Rowe(Director)

Co-investorsALAlpha EdisonARARHW HoldingsREReimagined VenturesUCUCLA Ventures

NeuralRad builds an AI platform (NeuralRad Brain) for stereotactic radiosurgery, providing automated detection, segmentation, and multi-course tracking of brain metastases along with treatment planning and response monitoring tools.

AI & Machine LearningHealthtechMedical Devices

Hao Jiang

NeuraLynx builds neural recording data acquisition and analysis systems, including its Digital Lynx multichannel recording and stimulation platform, telemetry systems, and portable acquisition tools.

Deep TechHardwareHealthtech

BiotechHealthtechOregon City, US

Neil Roundy(Executive Officer, Director, Promoter)Rachel Dreilinger(Executive Officer, Director, Promoter)Coni Rosati(Director, Promoter)

BoardMichael Tippie(Director)

Neurinsight is a company that has received multiple government research grants from agencies including NINDS (National Institute of Neurological Disorders and Stroke), NIBIB (National Institute of Biomedical Imaging and Bioengineering), and SBIR programs, indicating work in neuroscience or biomedical research.

AI & Machine LearningBiotechDeep TechDigital HealthMedical DevicesSanta Fe, US

Stefan Posse(Founder)Dieter Dennig(CEO)Mary A. Jacintha(COO & CFO)Conrad Poelmans(CTO)

neuro42 develops a portable, FDA 510(k)-cleared MRI platform that brings neurological imaging directly to the patient rather than requiring transport to a facility.

Deep TechHealthtechMedical DevicesSan Francisco, US

AVAmit Vohra(Executive Officer, Director)inABAbhita Batra(Executive Officer, Director)Shibu Gangadharan(Executive Officer)

BoardKrishna R. Bhupal(Director)Rahul Talwar(Director)

Co-investorsFRFrontier Path VCSHShangBay Capital LLCSOSonder Capital

Neurodon develops small-molecule therapeutics that target cellular calcium imbalance and the endoplasmic reticulum stress pathway, using compounds that allosterically modulate the SERCA enzyme to restore calcium transport.

BiotechHealthtechCrown Point, US

Russell Dahl(Executive Officer, Director)BBBrunde Broady(Founder)in

Co-investorsELElevate Ventures

NeuroEM Therapeutics develops MemorEM, a wearable head device that administers transcranial electromagnetic treatment to treat cognitive decline and Alzheimer's disease.

Deep TechHealthtechMedical DevicesTampa, US

GAGary Arendash(Founder & Scientist Emeritus)inCPChuck Papageorgiou(Chief Executive Officer)in

BoardMitch Larimore(Director)Jonathan Gordon(Director)

Co-investorsBLBlueLake.vc

Neuroene Therapeutics develops a mitochondrial modulator drug discovery platform to identify clinical candidates for treating neurological diseases caused by mitochondrial dysfunction.

BiotechDeep TechHealthtechMedical Devices

Dr. Chan(Co-Founder and CEO)Dr. Chou(Co-Founder)

neuroFit develops eye-tracking technology and hardware for medical screening and performance assessment, originally created at NASA Ames Research Center.

Deep TechDefense TechDigital HealthHealthtechMedical DevicesMountain View, US

Dorion ListonQuinn Kennedy(Director of Aging Research)Collin BelangerDmitriy OrlovAli IsmaelRami Ersheid

NeuroGevity develops a sleep headband with biometric sensors and AI algorithms to assess brain health and detect neurophysiological biomarkers at home.

AI & Machine LearningBiotechDigital HealthHardwareHealthtechWellness & FitnessSanta Fe, US

Karen Crow(Executive Officer, Director)inBarry Jason Worchel(Executive Officer, Director)

Co-investorsTETechstars

NeuroLux develops ultra-miniaturized, flexible optoelectronic devices for implantation into brain regions, enabling wireless power delivery and control for optogenetic research and drug delivery applications.

BiotechDeep TechHardwareMedical DevicesEvanston, US

John A. Rogers(Co-Founder)Anthony R. Banks(CEO and Co-Founder)Robert W. Gereau(Co-Founder)Michael R. Bruchas(Co-Founder)

Neuronoff develops Injectrode, a needle-delivered electrode platform for minimally invasive neuromodulation to treat chronic pain and neurogenic bladder in spinal cord injury patients.

AI & Machine LearningHealthtechMedical Devices

Manfred Franke, PhD(CEO & CO-FOUNDER)Andrew Shoffstall, PhD(CSO & CO-FOUNDER)

NeurOptics develops pupillometry technologies for clinical decision-making in critical care, neurology, neurosurgery, and emergency medicine.

Deep TechHealthtechMedical DevicesIrvine, US

Kamran Siminou(Executive Officer, Director)William Worthen(Executive Officer, Director)inWillam Worthen(Executive Officer, Director)Joseph Kiani(Director)

BoardBMBob Mellen(Director)in

Co-investorsAPAphelion Capital

NeuroSigma is a bioelectronic medical device company that makes non-invasive external trigeminal-nerve stimulation systems to treat chronic neurological and neuropsychiatric disorders.

Digital HealthHealthtechMedical DevicesLos Angeles, US

LELeon Ekchian(Executive Officer, Director)Lodwrick M. Cook(Director)

BoardKirk Calhoun(Director)James Hindman(Director)

Co-investorsCHCheckmate Capital Group LLC

NeuroTheranostics develops therapeutics and biomarkers for treating brain damage from ischemia and trauma.

BiotechDeep TechHealthtechMedical DevicesDetroit, US

Dr. John Anagli(Founder/CEO/CSO)

Neurotrack provides remote cognitive assessment tools for clinicians to detect early cognitive decline through eye-tracking technology, enabling earlier intervention for patients at risk of Alzheimer's and cognitive conditions.

AI & Machine LearningDigital HealthHealthtechMedical DevicesRedwood City, US

EKElli Kaplan(Co-founder & CEO)inDSDr. Stuart Zola(Scientific Co-founder)DEDr. Elizabeth Buffalo(Scientific Co-founder)CMCecelia Manzanares(Co-founder)

BoardMichael Johns(Director)

Co-investorsRERethink ImpactSOSozo VenturesVEVenture Capital Investment Management

Neutrolis is a clinical-stage biotech developing first-in-class therapies that degrade neutrophil extracellular traps (NETs) to address the root cause of autoimmune and inflammatory diseases such as lupus and rheumatoid arthritis.

BiotechHealthtechCambridge, US

AHAbdul Hakkim Rahamathullah(Director, Executive Officer, Promoter)Toby Fox(Director, Executive Officer, Promoter)

BoardGerald Chan(Director)Anthony Aiudi(Director)John Sundy(Director)

Co-investorsPRPrefix Capital

Neva EM builds experimentally validated computational human body models that let engineers simulate how devices interact with human anatomy across electromagnetic, computational fluid dynamics, thermal, and structural domains.

Deep TechHealthtechMedical Devices

New England Discovery Partners provides synthetic organic and medicinal chemistry services to pharmaceutical, biotechnology, academic, and government organizations for drug discovery and development programs.

BiotechDeep TechNew England, US

Michael Van Zandt(President & CEO)

Kemvera develops bio-based and CO₂-derived drop-in chemicals, with flagship products bio-acetic acid and bio-ethyl acetate produced from Midwest corn ethanol, aimed at helping brand owners reduce the carbon footprint of everyday products.

CleantechClimate TechNew Materials

Chern-Hooi Lim(Founder & CEO)

The New Mexico Start-Up Factory creates and commercializes technology-based companies by working with innovations from academic institutions and national laboratories.

AgTechDeep TechImpact & Social GoodAlbuquerque, US

John Chavez(Managing Director)Melissa Firestone(Company Creation Specialist)Sofia Ortiz(Project Manager)

New Scale Technologies designs and manufactures miniature motion systems and robotic inspection tools for use in medical devices, smartphone cameras, robotic automation, and precision metrology.

Advanced ManufacturingDeep TechDefense TechHardwareRoboticsVictor, US

David A. Henderson(CEO and Founder)

NewHaptics develops patented tactile display technology that enables large-area refreshable braille and tactile graphics screens for people who are blind.

Deep TechDigital HealthHardwareImpact & Social GoodMedical DevicesAnn Arbor, US

Alex Russomanno(CEO)Sile O'Modhrain(CXO)Brent Gillespie(CTO)

Newomics develops the UniESI system, a multiomics front-end platform using its M3 emitter and MEA chip "multispray" technologies for microflow and nanoflow LC-MS.

BiotechDeep TechHardwareBerkeley, US

PMPan Mao(Director)inDWDaojing Wang(Executive Officer, Director)inPatrick Scannon(Director)

BoardTHTed Hou(Director)in

Co-investorsBEBerkeley CatalystLDLDV PartnersMSMSA Capital

HealthtechChester Springs, US

Theresa Mansi(Executive Officer)inStephen Tullman(Executive Officer, Director)

BoardDennis Langer(Director)Jeff Himawan(Director)Christopher Molineaux(Director)Louis Manzi(Director)

Nexgenia develops proprietary stimuli-responsive polymer-based reagents for molecular and cellular selection, diagnostics, and immunoassays.

BiotechDeep TechNew MaterialsSeattle, US

RMRon Myers(Executive Officer, Director)

BoardSteven Gillis(Director)Charles P. Waite(Director)Martin Simonetti(Director)Stewart Parker(Director)David Urdal(Director)

Co-investorsTHThe W FundALAlliance of AngelsWRWRF Capital

NexImmune is a biotechnology company developing antigen-directed immunotherapies based on its proprietary AIM nanoparticle platform, which mimics dendritic cell signaling to activate antigen-specific T cell responses.

BiotechMedical DevicesGaithersburg, US

Jonathan Schneck(Director)Alain Cappeluti(Executive Officer, Director)Kenneth Carter(Executive Officer, Director)

BoardJanis Naeve(Director)James Barrett(Director)

Co-investorsPFPfizer Venture InvestmentsRARapha Capital Management, LLCNENew Enterprise Associates (NEA)

NextGen Jane runs a longitudinal molecular study of women's menstruation, using an at-home organic cotton tampon collection kit that members mail in to derive genomic insights from uterine samples.

BiotechDigital HealthFemTechHealthtechOakland, US

SGStephen Gire(Director)RTRidhi Tariyal(Executive Officer, Director)in

Co-investorsMAMaterial Impact

NextStep Robotics develops AMBLE, a wearable robotic device for foot drop rehabilitation in stroke survivors and other neurological conditions.

HealthtechMedical DevicesRoboticsBaltimore, US

Anindo Roy(Executive Officer, Director, Promoter)Richard Macko(Executive Officer, Director)Larry Forrester(Executive Officer, Director)BHBrad Hennessie(Founder)in

BoardBRENDA FURLOW(Director)ERIKA SMITH(Director)

Co-investorsMAMaryland TEDCOTETEDCOUNUniversity System of Maryland Momentum Fund

NFlection is a biopharmaceutical company developing novel therapeutics.

BiotechMedical DevicesBoston, US

CPChristopher Powala(Chief Development Officer, Former President & CEO)Mark de Souza(Executive Officer, Director)in

BoardCorey Goodman(Director)KPKetan Patel(Director)in

Co-investorsF-F-Prime CapitalVEvenBio PartnersVEvenBio Global Strategic

Co-investorsBEBetter Food VenturesUNUncork CapitalUPUpfront Ventures

Nimbic Systems provides surgical products including Mizuho OSI surgery tables, pressure injury abatement products, and disposables for operating room use.

HardwareHealthtechMedical Devices

Nirvana Sciences develops dyes, probes, and contrast agents for life science applications, including organic dyes with narrow emission profiles and a library of over 700 chlorin and bacteriochlorin designs.

BiotechDeep TechHealthtechNew MaterialsResearch Triangle Park, US

Russell Thomas(Executive Officer, Director, Promoter)

BoardRichard West(Director)Lisa Cooper(Director)Wayne Brinster(Director)

Co-investorsCHCharlotte Angel FundIDIDEA NC

NECi develops enzyme-based test kits and reagents for measuring nitrate and phosphate in water, soil, forage, plant tissue, and other samples.

AgTechBiotechCleantechNew MaterialsLake Linden, US

Dr. W.H. (Bill) Campbell(Founder)Ellen R. Campbell(Founder)

Scottsdale, US

CRAIG WEISS(Executive Officer, Director)JEFFREY WEISS(Executive Officer, Director)

BoardMICHAEL FARELLO(Director)DOUGLAS TEITELBAUM(Director)ELIE WURTMAN(Director)ADAM DRAIZIN(Director)

Co-investorsALAlpha Wave GlobalEVEvolution VC PartnersMIMiller Capital Corporation

Noom offers psychology-based weight-loss programs that combine behavior-change lessons, human and AI coaching, and access to prescription GLP-1 medications through its telehealth platform.

Digital HealthHealthtechWellness & FitnessNew York City, US

SJSaeju Jeong(Co-founder)inAPArtem Petakov(Co-founder)inGCGeoff Cook(Chief Executive Officer)inRFRichard Friedman(Chief Technology Officer)inPSPeter Scherr(Chief Marketing Officer)inJBJim Bugden(Chief Financial Officer)

Co-investorsACActivate Venture PartnersADAdit Ventures Management, LlcAGAglae VenturesCACAVU Consumer PartnersOAOak HC/FTQUQualcomm Ventures+8 more

BiotechPortland, US

VLADIMIR BOGIN(Executive Officer, Director)

Noctrix Health develops clinically validated wearable therapeutics for managing chronic neurological disorders, with its first product Nidra receiving FDA De Novo authorization and dedicated CMS HCPCS codes.

Digital HealthMedical DevicesWellness & FitnessPleasanton, US

SRShri Raghunathan(Founder)inShriram Raghunathan(Executive Officer, Director)

BoardChau Khuong(Director)inAllan May(Director)MJMudit Jain(Director)inTPTracy Pappas(Director)in

Co-investorsANAngelini VenturesBLBlue Venture FundsJOJoyance PartnersOROrbiMedTRTreo Ventures, LlcZÜZühlke Ventures+3 more

Nodexus manufactures flow cytometry and particle sorting instruments for life sciences research and cell analysis workflows.

BiotechDeep TechHardwareMedical Devices

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Nokomis develops ADEC, a non-invasive diagnostic system that detects counterfeit, defective, and maliciously modified electronic components and circuit boards by analyzing their unintended radio frequency emissions.

Advanced ManufacturingCybersecurityDeep TechDefense TechHardwareCharleroi, US

NWRA is a research organization specializing in geophysical and space sciences, providing scientific research services and supporting basic and applied research.

Climate TechDeep TechSpace Tech

BiotechSeattle, US

Thomas Neumann(Executive Officer, Director)inAlan C. Nelson(Executive Officer, Director)

BoardWalter L. Robb(Director)Sharon K. Everson(Director)Kriss Hammond(Director)

Co-investorsSESeaChange

NOTA Laboratories develops nitric oxide delivery platform technologies for healthcare applications, including intravascular catheter lock solutions designed to reduce infection and thrombosis risk.

BiotechHealthtechMedical DevicesAnn Arbor, US

Mark Meyerhoff(Founder and Chairman, Scientific Advisory Board)

Nova Thin Film develops oral soluble film (OSF) drug delivery technology called DepoFilm, working with pharmaceutical partners on proprietary products as well as its own drug candidates.

BiotechHealthtechMedical Devices

Joseph Fuisz(Management/Board (JD))Madhu Hariharan(Management/Board)Kurt Lauenstein(Management/Board)

NovaFlux develops medical devices using proprietary two-phase flow technology to sterilize medical channels, remove biofilm, and enable drug delivery, with applications in hemodialysis, infection control, and otitis media treatment.

Deep TechHealthtechMedical DevicesNew Jersey, US

Mohamed E. Labib(Chief Executive & Chief Scientific Officer)

Pelthos Therapeutics is a biopharmaceutical company that develops and commercializes topical treatments for infectious skin conditions and parasitic infestations.

BiotechHealthtechMedical DevicesDurham, US

Mark Schoenfisch(Executive Officer, Director)Nathan Stasko(Executive Officer, Director)

BoardRobert A Ingram(Director)Sean Murphy(Director)W Kent Geer(Director)John W Palmour(Director)

Co-investorsHAHatteras Venture Partners

Co-investorsBIBig Red Ventures

NovelMed develops antibody therapies targeting diseases with dysregulated complement systems, including rare and non-rare conditions affecting hematological, renal, inflammatory, and ocular systems.

BiotechDeep TechHealthtechLongevityMedical Devices

Noveome is a clinical-stage biopharmaceutical company developing ST266, a multi-targeted secretome containing hundreds of biologically active proteins designed for neuroprotection, inflammation modulation, and tissue healing.

BiotechHealthtechMedical DevicesPittsburgh, US

PWPatrick Welch(Executive Officer)Gretchen Kraemer(Executive Officer)inWGWilliam Golden(Executive Officer, Director)inACA. Clarke Atwell(Executive Officer, Director)inKarin Potoka(Executive Officer)inLBLarry Brown(Executive Officer)in

Co-investorsCACarnegie Mellon University

Novici develops DNA error correction technology for synthetic biology applications and manufactures recombinant antibodies, enzymes, and vaccines using plant-based production systems.

BiotechDeep TechVacaville, US

NovoMedix is a biotech company developing therapies for cancer and fibrosis by leveraging expertise in drug discovery, development, and biomarker identification.

BiotechDeep TechMedical DevicesSan Diego, US

Cathy A. Swindlehurst(Founder & CEO)Kyle W.H. Chan(Cofounder & CSO)

NovoPedics is developing MeniscoFix, a resorbable implant placed via arthroscopically-assisted surgery to replace the entire medial or lateral meniscus of the knee, intended to relieve pain, restore mobility, and prevent osteoarthritis in patients with severe meniscal injuries.

BiotechHealthtechMedical DevicesMonmouth Junction, US

Charles J. Gatt, Jr., MD(Founder & CEO)Michael G. Dunn, PhD(Founder & Secretary/Treasurer)Kevin Weadock, PhD(Chief Operating Officer)

Co-investorsFOFoundation Venture Capital Group, LLC

NovoPyxis applies mathematics and physics principles, including knot theory and fluid dynamics, to drug design and delivery, predicting protein structures of uncrystallized targets and designing peptide agonists.

BiotechDeep TechMedical DevicesCambridge, US

Daniel Vannoni(Director)Raja Srinivas(Director)inMadhavi Gavini(Executive Officer, Director)

Co-investorsBABantam Group

NOVUSON develops biomedical instrumentation and medical devices, serving healthcare organizations and clinical environments.

BiotechDeep TechHardwareHealthtechMedical DevicesBothell, US

SBStuart B. Mitchell(CEO, Founder and Chief Science Officer)inFrancesco P Curra(Executive Officer, Director)Christoph E Mack(Executive Officer, Director)

Co-investorsKEKeiretsu Forum

NOWDiagnostics develops rapid, point-of-care and consumer diagnostic tests.

BiotechDigital HealthHealthtechMedical DevicesBentonville, US

KCKevin Clark(Executive Officer, Director, Promoter)inLNLisa Nibauer(Chief Executive Officer)in

BoardJWJeremy Wilson(Director, Promoter)inCBClete Brewer(Director, Promoter)inDDDoug Degn(Director)John Harley(Director)

Co-investorsDIDigitalDx VenturesNENewRoad Capital Partners, LLCPOPortfolia

BiotechSan Bruno, US

Guido Lanza(Executive Officer, Director)JGJohn Griffin(Executive Officer)

BoardBruce Booth(Director)Steve Hall(Director)Lucio Lanza(Director)

NuPulseCV develops the Voyage device, a cardiac support technology aimed at patients with heart failure who are treated at both major institutions and community hospitals.

BiotechHardwareHealthtechMedical DevicesRaleigh, US

VALLUVAN JEEVANANDAM(Director)GREG SCOTT(Director)RICHARD SHERMAN(Director)ALEX SHLYANKEVICH(Director)SONNA PATEL-RAMAN(Executive Officer)DADOUGLAS ALTSCHULER(Executive Officer, Director)

Co-investorsBRBroadview Ventures

NuShores Biosciences is a medical device company developing first-to-market technologies, with a focus on bone and tissue regeneration and joint replacement applications.

BiotechHealthtechMedical DevicesNew MaterialsLittle Rock, US

Alexandru S. Biris(Co-Founder & CTO)inAGAndrew G. Kumpuris(Founder and Advisor)David E. Anderson(Founder and Advisor; co-founder)inSharon Ballard(Executive Officer, Director)Alex S. Biris(Founder / CTO)

Nutriwyo is a preclinical and early-stage clinical contract research organization that validates structure-function claims for nutraceuticals, dietary supplements, functional foods, and medical devices, and develops novel therapeutics for chronic conditions.

BiotechHealthtechLongevityLaramie, US

Rama Nair(Founder & CEO)Sreejayan Nair(Co-Founder)

NuvOx Pharma is a clinical-stage pharmaceutical company developing NanO₂, an oxygen therapeutic drug intended to improve oxygen delivery from lungs to blood and to tissue in order to reverse tissue hypoxia.

BiotechHealthtech

Co-investorsBABand of AngelsMEMEDA AngelsHUHunniwell Lake Ventures LLCPAPasadena Angels

NVIGEN develops multifunctional, biodegradable magnetic nanoparticles (nanobeads) and related assays for the biomedical research and diagnostics community, supporting applications such as NGS sample preparation, DNA/RNA/protein/exosome/cell isolation, liquid-biopsy immunodiagnostics, drug delivery, and cell therapy.

BiotechHealthtechMedical DevicesSunnyvale, US

Aihua Fu(Executive Officer, Director, Promoter)inXiangdong Jin(Executive Officer)

BoardGuoliang Yu(Director)

Co-investorsFOFoothill Ventures

NXT Biomedical is a medical device incubator that develops and spins out startups building clinical medical technologies aimed at addressing unmet needs and reducing healthcare costs.

BiotechHealthtechMedical DevicesIrvine, US

Stanton Rowe(CEO)inDon Bobo(Director)

BoardKadhiresan V Kadir(Director)AEAndrew ElBardissi(Director)inSteven Hochberg(Director)Andrew Cleeland(Director)

Co-investorsDEDeerfield Management Company

Nytricx develops biomedical devices and materials leveraging nitric oxide chemistry and fiber optic technology for wound healing, catheter applications, and extracorporeal circuits.

BiotechDeep TechHealthtechMedical DevicesHoughton, US

Ronald Shebuski(President and CEO)

ORRxD is a preclinical drug discovery company that uses structure-based, high-performance-computing-driven virtual high-throughput screening for hit discovery, along with medicinal chemistry and biological validation.

AI & Machine LearningBiotechDeep Tech

Oak Therapeutics develops pharmaceutical and biotechnology products, with a focus on improving health outcomes for underserved populations including children in developing countries.

BiotechHealthtechMedical Devices

Ed Maliski(Chief Executive and Chief Science Officer)Gerhard Apfelthaler(Chief Business Officer)

4Saliva provides custom product development services for saliva collection kits and diagnostic testing tools, partnering closely with clients from design through manufacturing and assembly.

Advanced ManufacturingBiotechDigital HealthHealthtechMedical Devices

ObjectiveEd develops digital curriculum and performance monitoring tools designed for students with disabilities, as well as the parents and professionals supporting their education.

AI & Machine LearningEdTechImpact & Social Good

Co-investorsGOGood Growth Capital

Co-investorsANAnthem Venture Management, Llc

Ocean Nanotech manufactures and sells specialized nanoparticles and reagent kits for research and diagnostic applications in life sciences.

BiotechDeep TechNew MaterialsSan Diego, US

Oceanit develops a diversified portfolio of products across aerospace and defense, energy, life sciences, and sustainable engineering using fundamental science and deep technological knowledge.

AI & Machine LearningDeep TechDefense TechEnergyEnterprise SoftwareHonolulu, US

Patrick K. Sullivan(Co-founder and CEO)

OCMS Bio develops immunology-based technology for vaccine and infectious disease applications.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesKing of Prussia, US

Scott Dessain(Founder and Chief Scientific Officer)Thomas Halpern(COO)Onne Ganel(Business Development)

Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases.

AI & Machine LearningBiotechDeep TechMedical DevicesEmeryville, US

SKSri Kosuri(Co-founder)inRHRamsey Homsany(Founder)inRobert Andrade(Executive Officer, Director, Promoter)Maurice J. Costantini(Executive Officer, Director, Promoter)

Co-investorsANAndreessen Horowitz+N+ND Capital8V8VCCACarbon SiliconCACatalio Capital Management, LPEXExplorer Investments+10 more

Oculogica develops FDA-cleared concussion assessment devices that use proprietary eye-tracking technology to measure abnormal eye movements caused by traumatic brain injury.

BiotechDigital HealthHealthtechMedical DevicesNew York, US

RSRosina Samadani(Executive Officer, Director)USUzma Samadani(Director)inRobert Ritlop(Executive Officer)Pratipatti Laxminarain(Director)

BoardJEJill Enos(Director)inKathryn Swintek(Director)in

Co-investorsCOColle Capital PartnersSESeraph GroupSOSoutheast Minnesota Capital FundTITitletownTechGOGolden SeedsM1M12 (Microsoft's Venture Fund)

Oleo is a biotech company that develops functional molecules from discovery through commercial-scale production, using a platform to make rare compounds available consistently.

BiotechFoodTechHealthtech

Oligomerix is a biopharmaceutical company developing therapeutic compounds, with leadership focused on advancing drug candidates through clinical development stages.

BiotechDeep TechHealthtechLongevityMedical Devices

James Moe(CEO, Head Discovery & Strategy, Co-founder, Director)inEJEliot J. Davidowitz(Chief Scientific Officer, Co-Founder)Dr. Moe(Founder)Dr. Davidowitz(Founder)

Co-investorsCOCounterview Capital

Omega Optics develops integrated optical technologies and biosensing solutions, including silicon-based chips and printed photonics for sensing applications in chemical and biological detection.

BiotechDeep TechHardwareIoTNew MaterialsSemiconductorsAustin, US

OmegaQuant is a CLIA-certified laboratory offering fatty acid testing services, including Omega-3 Index, Prenatal DHA, and Mother's Milk DHA tests to researchers, clinicians, and consumers.

Digital HealthHealthtechMedical DevicesWellness & FitnessSioux Falls, US

Bill Harris(Founder, Former President)Jason Polreis(CEO)Kristina Harris Jackson

Omicron Biochemicals supplies a catalog of carbohydrates, nucleosides, and related chemical compounds for research and industrial applications.

BiotechDeep TechNew Materials

OmicsCraft provides AI-powered software tools and bioinformatics services to biomedical researchers for accelerating disease biomarker discovery.

AI & Machine LearningBiotechCloud ComputingHealthtechWashington, US

Omm Scientific supplies specialized chemical compounds and reagents for research purposes.

BiotechDeep TechMedical DevicesNew Materials

OmniSpeech develops speech technology based on research into the physiology of human speech, with applications in audio, automotive, and consumer electronics.

AI & Machine LearningDeep TechEnterprise SoftwareHardwareCollege Park, US

Carol Espy-Wilson(Founder & CTO)inDPDavid Przygoda(Chief Executive Officer)inRVReggie Van Lee(Executive Chairman)

Co-investorsBABackstage CapitalMAMaryland TEDCOTETEDCO

OmniCyte is a biotechnology company developing vaccines and cancer immunotherapies, including a SARS-CoV-2 vaccine program and immune-response engineering work conducted in collaboration with academic medical centers.

BiotechHealthtechMedical DevicesNew York, US

Peter Leonardi(Founder and CEO)Angel Pellicer(Founder and Investigator)

Co-investorsCOConnecticut Innovations

A multi-disciplinary group developing novel imaging devices for medical and scientific applications.

Deep TechHardwareMedical Devices

First-in-class biologic drug targeting the CD24-Siglec innate immunity signaling pathway.

BiotechRockville, US

Pan Zheng(Executive Officer)Yang Liu(Executive Officer, Director)Martin Devenport(Executive Officer)

BoardMiao Hong(Director)Karen Liu(Director)inKun-Liang Guan(Director)

Co-investors3E3E Bioventures CapitalHMHM Venture Partners

Co-investorsASAstellas Venture Management LLCIMIMM Investment Japan

BiotechBaltimore, US

Praveen Sinha(Executive Officer, Director)Daniel Roche(Director)Todd McNutt(Executive Officer, Director)

OncoSpherix develops small molecule therapeutics that block hypoxia-driven gene expression to treat cancers resistant to current treatments, including glioblastoma, melanoma, lung cancer, breast cancer, and pancreatic cancer.

BiotechHealthtechMedical DevicesAtlanta, US

Erwin G. Van Meir(Chief Scientific Officer, Scientific founder)Binghe Wang(Scientific founder)Margaret K. Offermann(President, Chief Executive Officer)

OncoSynergy is a clinical-stage immuno-oncology company developing monoclonal antibody therapeutics, including a pan-CD29 antibody and a PD1-targeting antibody.

BiotechHealthtechStamford, US

ACAnne-Marie Carbonell(Founder, CEO & Chief Medical Officer)inWSW. Shawn Carbonell(Executive Officer, Director)inRobert Dunkle(Director)

BoardASAllen Salmasi(Director)inHen Suh Park(Director)

Co-investorsCOConnecticut Innovations

Oncotherapy Solutions develops novel peptide drug conjugates and bispecific drug conjugates aimed at treating drug-resistant and metastatic solid tumors.

Biotech

Oncovir is a biotech company developing Hiltonol, an experimental viral mimic that activates innate and adaptive immunity for solid cancer and infectious disease treatment.

BiotechHealthtech

Clinical-stage oncology company developing cancer treatments

BiotechDel Mar, US

Dana McGowan(Treasurer and Secretary)Karen Lundgren(Vice President and Chief Scientific Officer)LGLauren G. Otsuki(Chief Business Officer)inJames Freddo(Chief Medical Officer)James B. Breitmeyer, M.D., Ph.D.(President and Chief Executive Officer)

BoardDavid F. Hale(Director)

Co-investorsMEMESA VERDE VENTURE PARTNERSVEVedanta Capital

Hayward, US

Mark Peterman(Executive Officer)

ONL Therapeutics is a clinical-stage biopharmaceutical company developing therapies to preserve sight by preventing Fas-mediated death of retinal cells, a cause of vision loss and blindness.

BiotechHealthtechMedical DevicesAnn Arbor, US

DZDavid Zacks(Co-Founder & Chief Scientific Officer)inDEDavid Esposito(Executive Officer, Director)inConstance Chang(Executive Officer)JKJohn K Freshley(Executive Officer, Director)inJAJeffrey A Jamison(Executive Officer)in

BoardAFAaron Fletcher(Director)in

Co-investorsEXExSight VenturesINInvest MichiganNONovartis Venture FundVIVisionary VenturesBIBios PartnersINInFocus Capital Partners, LLC+4 more

HealthtechMadison, US

Carl Gulbrandsen(Director)Benjamin Titz(Executive Officer, Director)Kevin W. Eliceiri(Director)Thomas R. Mackie(Executive Officer, Director)Adam J. Uselmann(Executive Officer, Director)Andreas Velten(Director)

Two Pore Guys is a diagnostics company developing a handheld nanopore-based analyte sensor for point-of-care testing, with applications including liquid biopsy cancer detection.

BiotechDeep TechDigital HealthHardwareMedical DevicesSanta Cruz, US

Co-investorsKHKhosla VenturesDEDEFTA Partners

Ontogen provides end-to-end product development services for medical device companies, covering regulatory strategy, engineering, verification and validation, quality systems, and ISO 13485 manufacturing.

Advanced ManufacturingHealthtechMedical Devices

Open Source Instruments manufactures implantable biotelemetry devices and monitoring equipment for small animal research, including transmitters, electrodes, sensors, and data acquisition systems.

BiotechDeep TechDeveloper ToolsHardwareMedical Devices

Kevan Hashemi(President)James BensingerMichael Bradshaw

A care coordination platform that connects patients' behavioral and physical health data across providers, health plans, and government agencies, delivering real-time alerts, controlled substance data, and analytics inside clinical workflows.

AI & Machine LearningDigital HealthHealthtech

OpenLattice builds open-source data integration and platform software, including REST APIs, SDKs and database sync tools.

Redwood City, US

Matthew Tamayo-Rios(Executive Officer, Director)Patrick Grady(Director)

BoardRBRon Bouganim(Director)in

Co-investorsBUBullpen CapitalGOGovtech Fund

OpiAID offers an AI-powered recovery intelligence platform that combines EHR data with biometric data from commercial wrist-worn wearables and applies machine learning to quantify withdrawal symptoms and support clinical decision-making.

AI & Machine LearningDigital HealthHealthtech

Co-investorsIDIDEA NC

Co-investorsCWCWRU Technology Ventures

Opsin Biotherapeutics develops gene therapies to treat chronic pain by converting pain-blocking neurons into photoreceptors that can be activated with red LED light.

BiotechDeep TechDigital HealthHealthtechMedical Devices

Bob Benkowski(CEO and co-founder)Dr. Mohanty(co-founder)

Opticent Health develops Aurora X4, a free-standing OCT imaging platform for clinical research of the human eye that combines hardware and software with advanced features like pupil monitoring and NIR scanning laser ophthalmoscopy for patient alignment and imaging.

AI & Machine LearningBiotechHealthtechMedical Devices

Optimeos develops a nanoparticle-based drug formulation and delivery platform (CINCs and LINCs) for complex biologics including mRNA, DNA, peptides, and proteins, targeting rare diseases, immunology, and metabolic conditions such as obesity.

BiotechDeep TechHealthtechPrinceton, US

Robert K. Prud'homme, PhD(Director)BPBob Prud'homme(Leadership (PhD))RPRob Pagels(Leadership (PhD))CMChet Markwalter(Leadership (PhD))inSHShahram Hejazi, PhD(Executive Officer, Director)inSHShahram Hejazi(Leadership (PhD))in

Co-investors7G7G BioVenturesANAnzu PartnersHAHatch BioFund

OptTek develops optimization and analytics software for solving complex systems problems across Fortune 500 companies, government agencies, and the U.S. military.

AI & Machine LearningData & InfrastructureDefense TechEnterprise SoftwareGovTechBoulder, US

James KellyManuel LagunaFred Glover

Philadelphia, US

Bernardo Cordovez(Executive Officer)Robert Wicke(Executive Officer, Director)Robert Hart(Executive Officer)

Optosurgical develops imaging technologies that deliver real-time structural and functional tissue information to surgeons, aiming to make critical anatomy visible during thyroid, bile duct, abdominal, and other complex surgeries.

Deep TechHealthtechMedical Devices

BiotechHalifax, US

Charles H Rogers(Executive Officer, Director)

BoardPorter Anderson(Director)Kenneth Danielson(Director)

Lenexa, US

Cory Berkland(Executive Officer, Director)MFMaria Flynn(Executive Officer, Director)in

BoardBowman Fishback(Director)James Clarke(Director)

Influents Innovations (Or-Bis) develops evidence-based programs and digital products that apply behavioral research and technology to challenges in health care, social services, and education, addressing areas such as perinatal depression, early literacy, oral health, and youth tobacco prevention.

Digital HealthEdTechHealthtech

Organix provides custom synthesis, drug delivery, polymer chemistry, and analytical services for biotech, pharmaceutical, and materials science companies.

BiotechDeep TechEnterprise SoftwareNew MaterialsWoburn, US

Anu Mahadevan(CEO)Paul Blundell(President)

Organovo develops regenerative medicine therapies using bioprinting technology to treat serious liver diseases.

BiotechDeep TechHealthtechMedical Devices

Keith Murphy(Executive Chairman)

Co-investorsAUAurum Venture PartnersKHKhosla Ventures

Oricula Therapeutics develops small-molecule therapeutics for hearing loss and ototoxicity prevention, with a focus on aminoglycoside antibiotic-induced hearing damage.

BiotechHealthtechMedical DevicesSeattle, US

Edwin W. Rubel, PhD(University of Washington, Chaired Professor)David W. Raible, PhD(University of Washington, Professor)Julian Simon, PhD(Affiliate Associate Professor, University of Washington)

Origami Therapeutics is a preclinical-stage biopharmaceutical company developing protein degrader therapeutics to treat neurodegenerative diseases, starting with Huntington's disease.

BiotechDeep TechHealthtechMedical DevicesSan Diego, US

BHBeth Hoffman(Founder)inLSLeslie Schulze(Co-Founder and CFO)in

Co-investorsY Y CombinatorAJAJG

Origent develops predictive analytics and AI platforms for drug development and patient empowerment, helping pharmaceutical sponsors reduce clinical trial risk through patient-level forecasting and narrative health data capture.

AI & Machine LearningBiotechDigital HealthHealthtechMedical Devices

Orochem manufactures sample preparation products and devices for bioanalytical analysis, including extraction plates, filtration systems, and solid phase extraction cartridges used in pharmaceutical discovery, clinical diagnostics, and food safety testing.

Advanced ManufacturingBiotechHealthtechMedical DevicesNew MaterialsUSA, US

Anil Oroskar

Orphagen develops small molecule therapies targeting unexplored members of the nuclear receptor superfamily for cancer and other serious diseases.

BiotechHealthtech

Scott Thacher(CEO & Founder)

OrthoPreserve develops a minimally invasive meniscus implant for orthopedic care, designed to address unmet clinical needs in knee surgery.

BiotechHealthtechMedical DevicesHenrico, US

JSJonathan Schwartz(Chief Executive Officer)inCKCyrus Kump(Chief Medical Officer)

Co-investorsATAtlanta Technology Angels

Orthobond develops proprietary antimicrobial nanosurface technology that covalently binds to metallic and polymeric surfaces to mechanically kill bacteria, viruses, and fungi without antibiotics or eluting chemicals.

HealthtechMedical DevicesNew MaterialsMonmouth Junction, US

DNDavid Nichols(CEO)inPeter Goodwin(Director)Frank Cammisa(Director)Khalil Barrage(Director)inLisa D'Urso(Director)David Helfet(Director)

Co-investorsKIKineticos Disruptor

Orthocare Innovations designs and manufactures prosthetic and orthotic devices that automatically adapt to users' movements and integrate mobile technology to deliver real-time activity data to clinicians.

HealthtechMedical DevicesRoboticsSaaS

David Boone

Oryn Therapeutics develops Orynotides, programmable macrocyclic peptide therapeutics engineered to engage challenging extracellular and intracellular targets and modulate disease-driving biological networks.

BiotechDeep Tech

Ossium Health develops cellular therapies and bioengineered products for clinical use, leveraging adult stem cell technologies and advanced cell processing platforms.

BiotechHealthtechMedical DevicesSan Francisco, US

KCKevin Caldwell(CEO, Co-Founder & President)inDr. Woods(Chief Science Officer, Co-Founder, EVP, CLIA Laboratory Director)SGSebastian Giwa(Director)inEWErik Woods(Founder)in

BoardWTWilliam Trenchard(Director)inThomas Cycyota(Director)

Co-investorsALAlumni VenturesFEFemHealth VenturesFIFirst Round CapitalGEGeneral CatalystHEHemisphere Ventures LLCMAManta Ray Ventures+4 more

Osteocentric develops orthopedic implant systems for bone fixation, including fasteners, plates, and surgical instruments that use UnifiMI mechanical integration technology.

BiotechHardwareHealthtechMedical DevicesAustin, US

Co-investorsJSJStar Capital Investments

Otis Dental offers bruxism (teeth grinding) relief products with a focus on the connection between mental and oral health.

ConsumerDigital HealthDirect to ConsumerHealthtechWellness & Fitness

OtoNexus Medical Technologies is developing an ultrasound-based otoscope (Novoscope) that uses a miniaturized sensor in a single-use ear speculum tip to give clinicians objective, point-of-care data on middle-ear fluid and infection type.

AI & Machine LearningDigital HealthHardwareHealthtechMedical DevicesSeattle, US

CCCaitlin Cameron(Chair & CEO)in

Co-investorsGOGolden SeedsDEDellin InvestmentsFAFarvatn VentureKEKeiretsu ForumMIMindshift CapitalPOPortfolia+4 more

Oui Therapeutics develops prescription digital therapeutics aimed at suicide prevention, including what it describes as the first digital therapeutic for suicide, currently in clinical trials.

BiotechDigital HealthMental HealthNew Haven, US

Co-investorsCUCU Healthcare Innovation FundCVCVS Health VenturesFLFlare Capital Partners

Outcome Referrals provides a behavioral health assessment and matching system called the Treatment Outcome Package (TOP) to connect patients with personalized mental health care and help payers implement value-based reimbursement models.

AI & Machine LearningDigital HealthHealthtechMental HealthFramingham, US

DRDavid R. Kraus, PhD(Founder & President)DRDavid R. Kraus(President and CEO)

Outcomes4Me is an AI-driven patient platform that integrates with NCCN clinical oncology guidelines to provide personalized cancer care guidance, treatment options, clinical trial recommendations, and genetic testing information.

AI & Machine LearningDigital HealthHealthtechCambridge, US

MRMaya R. Said(Founder and CEO)inOsama Rahma(Founder)inMRMaya R. Said, Sc.D.(Founder and CEO)

BoardAJAndrea Jackson(Director)inDavid Fleshman(Director)David Auckland(Director)

Co-investorsASAsset Management CompanyHEHealthX VenturesSISierra VenturesASAsset Management VenturesNONorthpond Ventures

OvaryIt provides a pre-evaluation screening platform that identifies which contraceptive categories are safe for individual women based on their medical history, and facilitates access to appropriate contraceptive options through pharmacies.

Digital HealthFemTechHealthtechWellness & Fitness

Mary Kucek(Founder, CEO)

Oxalo Therapeutics is a preclinical-stage biopharmaceutical company developing therapies to treat and prevent diseases caused by hyperoxaluria and hyperoxalemia, such as recurrent calcium oxalate kidney stones.

BiotechHealthtechChicago, US

Yang Zheng(Co-founder, Business lead)inHatim Hassan(Co-founder, R&D lead)

Oxford Biomedical Research develops research products including assays, antibodies, and enzymes for drug metabolism and biochemical applications.

BiotechDeep TechDigital HealthHealthtechMedical DevicesRochester Hills, US

Denis M. Callewaert(Founder)

Oxford Performance Materials develops additive manufacturing (3D printing) technology and high-performance PEKK thermoplastics and coatings.

Advanced ManufacturingMedical DevicesNew MaterialsSouth Windsor, US

Scott DeFelice(Executive Officer, Director)inJDJordan DeFelice(Executive Officer, Director)inPMPaul Martin(Executive Officer, Director)inSeverine Zygmont(Executive Officer, Director)Anthony DeCarmine(Executive Officer)Christopher Codeanne(Executive Officer)in

OyaGen is a preclinical drug discovery and development company that identifies and optimizes lead compounds as investigational new drugs for infectious diseases and cancer, then licenses or partners them with industry leaders for clinical development.

BiotechDeep TechHealthtechRochester, US

HCHarold C. Smith(Founder)inRyan P. Bennett(CSO & Laboratory Director)Richard McCloskey(Director)Thomas Fitzgerald(Chief Operations Officer)Richard Ogden(Director)Roscoe Moore(Director)

Pacific Optica develops optical and photonic components including objectives, scan lenses, and imaging systems for applications in neuroscience research, bioengineering, clinical investigations, and advanced manufacturing.

BiotechDeep TechHardwareMedical DevicesSanta Barbara, US

Spencer LaVere Smith, Ph.D.(CEO)Che-Hang Yu, Ph.D.(Engineering)Ryan P. McGreal, M.S.(Operations)

Packet Digital develops power systems and power management technologies for autonomous systems operating in air, sea, land, and space, including unmanned aircraft and solar products.

Deep TechDefense TechEnergyHardwareIoTRoboticsFargo, US

TZTerri Zimmerman(CEO)inAPAndrew Paulsen(CTO)inJeff Jonson(Director)Ronald Robson(Executive Officer)John, Dr. Cook(Director)Linda Pancratz(Director)

Co-investorsDADakota Venture Group

PAI Life Sciences is a contract research organization specializing in developmental and translational research for vaccines, diagnostics, and therapeutics, with lab facilities for molecular, immunological, and chemical research.

BiotechHealthtechMedical DevicesSeattle, US

Darrick Carter(CEO)Gail Cassell(Distinguished Scientist)

BiotechKennett Square, US

FMFrank Minella(Executive Officer, Director)inAlexander Ruckdaeschel(Executive Officer, Director)

BoardJohn H. Stewart(Director)Andrew Koopman(Director)

Co-investorsDEDelaware Crossing Investor GroupITItalian Angels for GrowthNYNYU Innovation Venture Fund

PAK BioSolutions builds automated systems and single-use flow kits for end-to-end continuous purification of biopharmaceuticals, running four continuous purification stages simultaneously for a stated 4X productivity gain over batch methods.

Advanced ManufacturingBiotechHardwareBurke, US

Pezzini Joanna(President)inKHKevin Hill-Byrne(Co-Founder & CTO)in

Co-investorsARArboretum Ventures

Palm Therapeutics develops palmitoylation-targeted drugs using its proprietary PalmReader screening platform to identify novel therapeutic molecules.

BiotechDeep TechMedical Devices

ARAndrew Rudd(Cofounder & CEO)in

Co-investorsTATachyon Ventures

BiotechPhiladelphia, US

Yi Xing(Director)Mingfu Zhu(Executive Officer, Director)Jimmy Lu(Director)

Co-investorsWIWI Harper Group

Parabon develops DNA-based therapeutic and forensic products, including the Snapshot platform for advanced DNA analysis used in medical research and forensic investigation.

BiotechDeep TechDefense TechGovTechMedical DevicesReston, US

Steven Armentrout(Co-Founder and CEO)Michael L. Norton(Co-Founder and Chief Science Officer)

Paradromics develops a brain-computer interface (BCI) system, with FDA Breakthrough Device Designations for speech decoding and digital device control, and works with academic medical institutions on translational BCI research.

BiotechDeep TechHealthtechMedical DevicesAustin, US

Matt Angle(Founder and CEO)in

Co-investors1515th RockALAlpha EdisonANAnthropy PartnersATATEL VenturesCACapital FactoryCOCoastCap+22 more

Parametric Studio develops STEM software and maker kits designed to teach science, technology, engineering and math to students through hands-on, technology-enabled learning experiences.

ConsumerEdTechHardwareSaaS

ParaTechs is a biotechnology company that develops technologies and products for discovery and development applications in biotechnology, built on intellectual property from the University of Kentucky.

AgTechBiotechDeep TechHardwareMedical DevicesNew MaterialsLexington, US

Dr. Bruce A. Webb(Co-founder)Dr. Fath-Goodin(Co-founder, Chief Executive Officer)