Define Ventures — Full Portfolio

Double Blind Bio builds AI agents that automate administrative workflows within clinical trial sites and sponsor operations, enabling faster and more efficient execution of clinical studies.

AI & Machine LearningHealthtechMedical DevicesSan Francisco, US

David Hughes(Executive Officer, Director)Shruti Tibrewala(Executive Officer, Director)

Co-investorsPEPeterson VenturesSISignalFire

9amHealth provides virtual care for cardiometabolic conditions, offering weight management, diabetes care, and heart health treatment that combines prescription medication (including GLP-1s), lifestyle coaching, and lab testing.

Digital HealthHealthtechWellness & FitnessEncinitas, US

FWFrank Westermann(Executive Officer, Director)inAKAnton Kittelberger(Founder)inMHMichael Hofner(Executive Officer)inAWAvantika Waring(Executive Officer)PGPaul Geevarghese(Executive Officer)inBSBernhard Schandl(Executive Officer)in

Board seatLynne Chou O'Keefe· per SEC Form D

Co-investors7W7wire VenturesCACalm/Storm VCCACatalio Capital Management, LPHAHabitat PartnersHAHansmann Family OfficePUPUSH Ventures+2 more

DexCare provides patient access and scheduling navigation logic for health systems, enabling patients to find available appointments across multiple care entry points and improving utilization of existing capacity.

HealthtechSaaSPhiladelphia, US

Board seatLCLynne Chou O'KeefeLynne Chou O?Keefe· per SEC Form D · $60M raise · filed Jun 2023

Co-investorsFRFrist Cressey VenturesKAKaiser Permanente VenturesSPSPRINGROCK VENTURESTRTRANSFORMATION CAPITAL

FOLX is a digital healthcare platform designed for LGBTQIA+ adults, providing inclusive and affirming medical care.

Digital HealthHealthtechBoston, US

ABA.G. Breitenstein(Founder)inLBLena Ballantine(Executive Officer)inLMLiana M Guzman Weis(Executive Officer, Director)

BoardMorgan Cheatham(Director)inLSLee Shapiro(Director)in

Board seatLynne Chou O'KeefeLynne Chou-O'Keefe· per SEC Form D

Co-investors7W7wire VenturesBEBessemer Venture PartnersCOCorewell Health VenturesHAHabitat PartnersSESeae VenturesBRBreyer Capital+2 more

Lightship provides clinical trial operations for biopharma companies, CROs, and academic institutions, offering site services, decentralized and hybrid trial models, patient recruitment, and mobile research units.

BiotechDigital HealthHealthtechEl Segundo, US

DMDavid MacMurchy(Chief Executive Officer)inMSMichael Shipton(Chief Business Officer)inDFDarcy Forman(Chief Operating Officer)inLVLindsay Van Pelt(Chief Medical Advisor)in

Board seatLynne Chou O'Keefe· per SEC Form D

Co-investorsHIHikma VenturesALALLEGIS CAPITALALAlumni VenturesCOCongruentCOCongruent VenturesHYHyperguap+5 more

Livongo offers a chronic condition management program combining connected health-monitoring devices (blood glucose meters, blood pressure monitors, scales), certified health coaches, and clinical support to help members manage diabetes, hypertension, and weight, including GLP-1 medication access.

Digital HealthHealthtechWellness & FitnessMountain View, US

JOSEPH E. CAREY(Executive Officer)BRIAN VANDENBERG(Executive Officer)MARIO CHRISTOPHER(Executive Officer)

BoardBSBETH SEIDENBERG(Board Director (Kleiner Perkins))inLSLEE SHAPIRO(Director)inHTHEMANT TANEJA(Director)in

Board seatLCLynne Chou O'Keefe· per SEC Form D · $52.5M raise · filed Mar 2017

Co-investors7W7wire VenturesCOCorewell Health VenturesGEGeneral CatalystHUHuman CapitalKLKleiner PerkinsSASapphire Ventures+4 more

MedArrive provides software for scheduling, routing, and real-time tracking of in-home care delivery teams.

HealthtechLogistics & Supply ChainSaaSNew York, US

IPInna Plumb(Executive Officer)inDTDaniel Trigub(Executive Officer, Director)

BoardWilliam Sullivan(Director)ACAnnie Case(Director)inAHAndy Harrison(Director)ABAgneta Breitenstein(Director)in

Board seatABA.G. BreitensteinLynne Chou O'Keefe· per SEC Form D

Co-investors7W7wire VenturesCOCobalt VenturesCOCorewell Health VenturesDEDeclaration PartnersKLKleiner PerkinsLELeaps by Bayer+2 more

MIGA is a multilateral organization that provides political risk insurance and credit guarantees to support private investment in developing countries.

FintechImpact & Social GoodInsurTechWashington, US

Walter Raymond Cooper(Executive Officer, Director, Promoter)TYTsutomu Yamamoto(Managing Director)inJKJunaid Kamal Ahmad(Vice President, Operations)EMEd Mountfield(Vice President and Chief Financial Officer)inADAriane Di Iorio(Director, Economics and Sustainability)MFMuhamet Fall(Director for Industries)in

Board seatLynne Chou O'Keefe· per SEC Form D · $4M raise · filed Jul 2025

Co-investorsTRTrade and Development BankADAdapt VenturesALAlumni VenturesASAsymmetric Capital PartnersFLFloating PointLULux Capital+2 more

Chicago, US

Board seatLynne Chou O'Keefe· per SEC Form D

Co-investorsBLBlue Venture FundsGVGV (Google Ventures)TWTwine Ventures

Blackbird Health provides comprehensive neuroscience-based evaluations and coordinated mental healthcare for children, combining psychiatric assessment, therapy, and medication management to create personalized treatment plans.

Digital HealthHealthtechMental Health

Amy Edgar(Founder)

Co-investorsFRFrist Cressey VenturesGRGreyMatter

Cleveland Clinic is a multi-specialty medical group practice and hospital system founded in 1921, providing patient care, medical research, and education.

Digital HealthHealthtechMedical Devices

Co-investorsFRFred Hutchinson Cancer Research CenterGEGeneral CatalystPEPeak XV PartnersY Y Combinator

Cohere Health provides a platform aimed at aligning the interests of patients, physicians, and health plans to support care decisions and improve member outcomes.

AI & Machine LearningDigital HealthEnterprise SoftwareHealthtechSaaSBoston, US

SNSiva Namasivayam(Executive Officer, Director)inRSRobert Shepardson(Executive Officer)inKCKristen Carucci(Executive Officer)inDuncan Reese(Executive Officer)

BoardDavid Barrett(Director)Amir Debourou(Director)

Co-investorsCOCota CapitalFLFlare Capital PartnersLOLongitude CapitalDEDeerfield Management CompanyFLFlare Capital StrategiesPOPolaris Partners+1 more

Concert Health operates a behavioral health medical group providing integrated mental health treatment services within primary care settings such as family medicine, women's health, and pediatric offices.

Digital HealthHealthtechMental Health

Co-investorsK2K2 HealthVenturesTOTown Hall VenturesHEHealthy VenturesSISierra VenturesVEVertical Venture Partners

Crescendo accelerates medical research by enabling clinical research participants to securely assemble and contribute their health data, while supporting patients with clinical care and safety consultations.

Data & InfrastructureDigital HealthHealthtech

Sam Roosz(Co-Founder, CEO)Michael Glassman(Co-Founder, President)

Evermore Outcomes operates a benefits card and retailer network that lets health plans dynamically add, update, and reload supplemental benefits on a member's card.

Data & InfrastructureDigital HealthHealthtech

Daryl Risinger(Founder)Jared D(Founder)Robby Knight(Founder)

Found offers clinically-led, personalized weight care that combines evidence-based medical treatment (including provider-prescribed medications) with support to help members lose weight and improve their health.

Digital HealthHealthtechWellness & Fitness

Co-investors1/1/1 CapitalABAble PartnersATAtomicIVIVP (Institutional Venture Partners)THThe Chernin Group (TCG Crypto)WEWestCap

Foundation Health offers an AI operating system for pharmacies that automates prior authorizations, refill authorizations, financial assistance enrollment, 340B compliance, and patient communications, along with a white-labeled digital pharmacy front door and a healthcare API.

AI & Machine LearningDigital HealthHealthtech

UAUmar Afridi(CEO & Founder)

Co-investorsCACalm/Storm VCEXExceptional CapitalPAPage One VenturesTRTranspose Platform Management

Centivo is a primary-care-centered health plan administrator for self-funded employers, sold through benefits brokers and consultants.

Digital HealthHealthtechInsurTech

Alan Cohen(Founder)inAshok Subramanian(Founder & CEO)Stuart Roth(Founder)in

Co-investorsALAlumni VenturesB B Capital GroupB4B4 CapitalBABasecamp FundF-F-Prime CapitalGPGPO Fund+5 more

Healthier Capital is a venture capital firm that invests in technology-enabled healthcare companies seeking to reduce costs and improve care delivery.

Digital HealthFintechHealthtech

ADAmir Dan Rubin(CEO and Founding Managing Partner)in

Co-investorsMOModi VenturesBLBlack Opal VenturesHEHealthier CapitalMAMacquarie CapitalMAMaverick VenturesONOncology Ventures+2 more

US direct-to-consumer telehealth company selling prescription and OTC treatments online by subscription; NYSE-listed as HIMS.

JAJack Abraham(Co-founder)in

Co-investors7G7GC & Co8V8VCA-A-Rod CorpATAtomicBRBrentwood AssociatesCACAVU Consumer Partners+17 more

Plug-and-play conversational AI platform enabling voice and chat interactions with information across digital channels.

IKIsrael Krush(Founder & CEO)inRCRom Cohen(Founder)in

Co-investorsBLBlack Opal VenturesDODorm RoomENEntrepreneurs Roundtable Accelerator (ERA)HAHanaco Venture CapitalHEHealthier CapitalK2K20 Fund+7 more

Laudio builds a SaaS platform that supports frontline leaders in hospitals and health systems, using data and analytics to improve employee engagement, retention, and operational outcomes.

AI & Machine LearningDigital HealthHR TechSaaSNewton, US

Russell Richmond, MD(Executive Officer, Director)TDTim Darling(Co-founder & President, Laudio Insights)inKevin Kumler(Director)Constantine John Floros(Executive Officer, Director)Lisa Mastrangelo(Executive Officer)Mike Caffrey(Director)

Co-investors.4.406 VenturesINInHealth VenturesMEMemorialCare Innovation Fund

Layer Health builds AI tools for hospitals and health systems that automate clinical registry abstraction and custom quality-metric extraction across service lines such as cardiovascular, surgery, and oncology.

AI & Machine LearningDigital HealthHealthtechBoston, US

David A. Sontag(Executive Officer, Director)inLMLuke Murray(Founder)inDivya Gopinath(Founder)in

BoardLOLynne O'Keefe(Director)inAPAnthony Philippakis(Director)in

Co-investorsEAEast Post Road VenturesFLFlare Capital PartnersGVGV (Google Ventures)

Lightship designs and builds the AE.1, an all-electric travel trailer for the RV market.

CleantechDirect to ConsumerHardwareMobility & TransportationBroomfield, US

Tobias Kraus(Executive Officer, Director)TKToby Kraus(Co-Founder & Chief Executive Officer)inBPBenjamin Parker(Founder)inHCHayley Cashdollar(Chief Operating Officer)inNHNick Herron(Chief Engineer)inRWRob Williams(Chief Creative Officer)in

Co-investorsCLClimacticCOCongruent VenturesHYHyperguapJEJetstreamOBObvious VenturesPRPrelude Ventures+5 more

Lightship Capital is a venture capital fund that invests in early-stage companies founded by underrepresented entrepreneurs, including founders of color, LGBTQ+ individuals, women, and innovators with disabilities.

AI & Machine LearningConsumerFintechImpact & Social GoodCincinnati, US

CMCandice Matthews Brackeen(General Partner)inBBBrian Brackeen(General Partner)in

Co-investorsATAtento CapitalALALLEGIS CAPITALALAlumni VenturesCOCongruentCOCongruent VenturesHYHyperguap+5 more

Luminai builds an AI-native operating system that unifies fragmented healthcare operational work streams to automate administrative and operational tasks across health systems.

AI & Machine LearningDeveloper ToolsEnterprise SoftwareHealthtechSaaSSan Francisco, US

KKKesava Kirupa Dinakaran(Founder)inHGHarsh Gupta(Founder)

Co-investorsMOMoxxie VenturesPEPeak XV PartnersSCScribble VenturesSHShrug CapitalUNUnderscore VCWAWayfinder Ventures+4 more

Marit is a free career platform for physicians and advanced practice providers (APPs) that offers crowdsourced, anonymous salary data and aggregated job listings from employers, associations, and job boards.

Digital HealthHealthtechHR Tech

RARob Anderson(Co-founder)in

Co-investors2525MadisonF-F-Prime CapitalREReach Capital

SanLuca is a clinician-first AI platform that integrates behavioral health into longitudinal chronic condition management for health systems and care teams.

AI & Machine LearningDigital HealthHealthtech

Co-investorsSESemperVirens Venture Capital

Tia is a healthcare platform that coordinates patient care by connecting care providers, clinical support, and care coordinators to manage appointments, prescriptions, billing, and procedures.

Digital HealthHealthtech

CWCarolyn Witte(Founder)in

Co-investorsACACME CapitalCOCompoundHOHomebrewSESeae VenturesTHThreshold VenturesTOTorch Capital+6 more

Unite Us provides software and data infrastructure for coordinating whole-person care, helping organizations identify social and health needs, deliver services, and track outcomes.

Digital HealthGovTechSaaSNew York, US

DMDaniel M. Brillman(Executive Officer)inTJTaylor Justice(Co-Founder and Chief Executive Officer)in

Co-investorsBLBlossom Street VenturesEQEqual Opportunity VenturesICICONIQOAOak HC/FTOPOptum VenturesPLPLUS Capital+6 more

Verana Health aggregates de-identified clinical data from a network of over 20,000 physicians in ophthalmology, urology, and neurology to power real-world evidence, clinical trial enablement, and quality reporting for pharmaceutical companies and healthcare providers using AI and machine learning.

AI & Machine LearningData & InfrastructureDigital HealthHealthtechSan Francisco, US

Mark Blumenkranz, MD(Co-Founder, Verana Health and Lagunita Biosciences)SJSujay Jadhav(Chief Executive Officer)in

Co-investorsNONovo HoldingsBRBreyer CapitalTETech Council VenturesVAValspring Capital