Takeda Ventures — Full Portfolio

Xilio Therapeutics is a clinical-stage biotechnology company developing masked immuno-oncology therapies that use protein engineering to remain inactive until activated by tumor-specific proteases within the tumor microenvironment.

BiotechHealthtechWaltham, US

RRRené Russo(Executive Officer, Director)inJoseph Farmer(Executive Officer)Timothy Clackson(Executive Officer)Christopher Frankenfield(Chief Financial and Operating Officer)inKLKatarina Luptakova(Chief Medical Officer)inPaul Clancy(Director)

Co-investorsBABain Capital Life SciencesBABay City CapitalF-F-Prime CapitalM M VenturesMRMRL Ventures FundRARA Capital+9 more

EvolveImmune develops immunotherapy treatments for cancer patients.

BiotechHealthtechMedical DevicesBranford, US

Stephen Bloch(Co-founder and Chief Executive Officer)inDonmienne Leung(Manager)Ian Taylor(Manager)Jay Fine(President, Research and Development)

BoardDYDerek Yoon(Manager)in

Board seatJasmina Marjanovic· per SEC Form D

Co-investorsSOSolasta VenturesPFPfizer VenturesELElm Street VenturesPFPfizer Venture Investments

BiotechSan Diego, US

Douglas J. Jolly(Founder)inCarlos E. Ibanez(Executive Officer)Robert Anthony Williamson(Director)Troy Wilson(Director)Michael Martin(Director)Nicholas A. Boyle, Ph.D.(Executive Officer, Director)

Co-investorsBIBioBrit

Telemedicine services for health systems, health plans, employers, and physicians

PGPhyllis Gotlibin

Co-investorsALAllianz XLGLG Technology VenturesMCMcKesson VenturesP5P5 Health VenturesPEPerot JainWAWaterline Ventures+1 more

HealthtechSaratoga Springs, US

DTDaniel T. Pickett III(Executive Officer, Director)Timothy Koehler(Executive Officer)Greg Stephen(Executive Officer)

BoardHolly Benson(Director)Mary Langowski(Director)Peter Dorsman(Director)

Co-investorsCLClaritas CapitalWHWhat If VenturesOLOlive Tree VenturesPIPivotal Life SciencesVIVista Equity Partners

Arcellx develops CAR T-cell therapies that are individually designed for each patient, using the immune system to target and attack cancer.

BiotechHealthtechGaithersburg, US

Han Lee(Executive Officer)RERami Elghandour(Executive Officer, Director)in

BoardJCJill Carroll(Director)inABAli Behbahani(Director)inDYDerek Yoon(Director)inTATiba Aynechi(Director)in

Co-investorsLGLG Technology VenturesNENew Enterprise Associates (NEA)QUQuan CapitalSASamsara BioCapitalSISixty Degree CapitalSOSolasta Ventures+4 more

Aspen RxHealth operates a community of pharmacists to deliver clinical pharmacy care and medication support for patients and health plan members.

Digital HealthHealthtechSaaS

Co-investorsBEBessemer Venture PartnersFLFlare Capital Partners

Biofourmis provides technology-enabled solutions and a platform for AI-driven in-home patient care, using wearable biosensors and remote monitoring to deliver and transition patients across levels of care.

AI & Machine LearningDigital HealthHealthtech

KSKuldeep Singh Rajput(Founder)in

Co-investorsINIntel CapitalCVCVS Health VenturesGEGeneral AtlanticMAMassMutual VenturesOPOpenspace Ventures

Boulder provides medication-assisted treatment for addiction through licensed specialists who prescribe buprenorphine, supported by dedicated care teams offering medical care, peer recovery coaching, and care coordination accessible via a digital platform.

Digital HealthHealthtechMental HealthBoulder, US

Stephanie Papes(Cofounder)Stephanie Strong(Founder)Jordan Nof(Director)Frank Ingari(Director)Josh Kopelman(Director)

Co-investorsADAdvance Venture PartnersALAlumni VenturesFIFirst Round CapitalGAGaingelsGRGreycroftLALaerdal Million Lives Fund+5 more

Code Biotherapeutics develops a proprietary non-viral 3DNA delivery platform for genetic medicines, RNAi, and other modalities, using targeting molecules to reach specific cells and tissues outside the liver.

BiotechDeep TechHealthtechHatfield, US

Lauren Kaskiel(Executive Officer)inRobert C. Getts(Executive Officer)BMBrian McVeigh(Executive Officer, Director)in

BoardDmitry Kuzmin(Director)Victor Stone(Director)Edward Mathers(Director)

Co-investorsNENew Enterprise Associates (NEA)4B4BIO CapitalAMAmgen VenturesHAHatteras Venture PartnersJDJDRF T1D FundNONorthpond Ventures+1 more

Crescendo Biologics develops novel immune cell-enhancing therapeutics for immuno-oncology using its patent-protected Humabody VH platform, a fully human domain technology clinically validated in oncology and immunology.

BiotechHealthtechMedical Devices

Co-investorsANAndera PartnersQUQuan CapitalSOSofinnova PartnersASAstellas Venture Management LLCEMEMBL VenturesFUFuture Planet Capital+3 more

Ensoma is a genomic medicine company developing a platform for in vivo engineering of hematopoietic stem cells (HSCs), combining an off-the-shelf delivery system with a gene engineering toolkit intended to treat diseases with a one-time treatment.

BiotechHealthtechMedical DevicesBoston, US

Albert Seymour(Director)

BoardKPKush Parmar(Executive Officer, Director)inPSPaula Soteropoulos(Director)SKStephen Knight(Director)in

Co-investors5A5AM VenturesAJAju IB InvestmentCACatalio Capital Management, LPDEDelos CapitalF-F-Prime CapitalSOSolasta Ventures+10 more

Enzyre develops a handheld diagnostic device that performs multiple blood coagulation assays in parallel to identify bleeding causes at the point of care.

BiotechDeep TechDigital HealthHealthtechMedical DevicesEindhoven, NL

WVWim van den Broek(CEO)inWaander(CSO)

Co-investorsI&i&i Biotech FundNONovalis BiotechOOOost NL

Cambridge, MA biotech developing engineered tRNA "protein editing" therapeutics for nonsense-mutation diseases; reported shut down in 2025.

Cambridge, US

LJLeslie J Williams(Executive Officer, Director)

BoardBenjamin Chen(Director)SMSeiji Miyahara(Director)inSacha Mann(Director)David Moskowitz(Director)SGSteven Gillis(Director)in

Co-investorsARARCH Venture Partners5A5AM Ventures8V8VCATAtlas VenturePAPanacea VentureTATaiho Ventures, LLC

ISHI offers a discharge transitions program that manages patient recovery during the post-hospital period with personalized care coordination and clinical insights for care teams and healthcare administrators.

AI & Machine LearningDigital HealthHealthtech

Dr. Ajay Srivastava(Founder)

Nabla is a drug development company that applies design discipline and scientific rigor to the development of new medicines.

AI & Machine LearningBiotechDeep TechHealthtechBoston, US

SBSurge Biswas(Founder)inFAFrances Anastassacos(Founder)inGeorge M. Church(Founder)Surge Biswas Frances Anastassacos(Founder)

Co-investorsCACantos VenturesFIFifty YearsPEPetriPIPillar VCRARadical VenturesSPSparta Group+6 more

Clinical-stage immuno-oncology company developing antibodies derived from the immune systems of 'Elite' cancer responders.

BiotechHouston, US

ABAlice Bexon(Executive Officer)inCJClifford J. Stocks(Director, Executive Officer)inKDKamal D. Puri(Executive Officer)inCRChris Russell(Executive Officer)inRuss Hawkinson(Executive Officer)

BoardSGSteven Gillis(Director)in

Co-investors3B3B Future Health FundCACanaan PartnersGRGreatPoint VenturesRIRiverVest Venture PartnersALAlexandriaARARCH Venture Partners+5 more

Oshi provides virtual gastrointestinal care delivered by gastroenterologists, dietitians, and gut-brain specialists to patients seeking treatment for GI conditions.

Digital HealthHealthtech

SHSam Holliday(CEO)in

Co-investorsBEBessemer Venture PartnersCVCVS Health VenturesFLFlare Capital PartnersFRFrist Cressey VenturesKOKoch Disruptive TechnologiesOAOak HC/FT+1 more

Palleon Pharma develops small molecule and biologic drugs targeting autoimmune and inflammatory diseases using proprietary glycoscience platforms.

BiotechDigital HealthMedical DevicesWaltham, US

Jim Broderick(Co-Founder)inJohn Hennessy(Executive Officer)Karen Hong(Director)James Lee(Director)Stephen Hoffman(Director)Li Peng(Chief Scientific Officer)

Co-investorsMAMatrix Capital ManagementPFPfizer VenturesPFPfizer Venture InvestmentsSRSR One Capital ManagementBIBioHealth Innovation, Inc.VEVertex Ventures HC

BiotechLexington, US

VMVictoria M. Richon(Executive Officer, Director)in

BoardCameron Wheeler(Director)Jonathan Root(Director)Laurence Lasky(Director)

Co-investorsAVAvego BioScience CapitalOUOUP (Osage University Partners)PEPeregrine VenturesABAbbVieDEDeerfield Management CompanyJJJJDC+3 more

Tele911 connects patients on scene with board-certified emergency medicine physicians via telehealth, bridging the gap between a 911 call and the emergency department to triage cases and reduce unnecessary ambulance and ER use.

Digital HealthHealthtechPasadena, US

RLRamon Lizardo(Executive Officer)inChristopher Maloney(Executive Officer, Director, Promoter)Marc Eckstein(Executive Officer, Director)

BoardJTJeff Trost(Director)inBruce Meadows(Director)

Co-investorsLALaerdal Million Lives Fund