Ono Venture Investment, Inc. — Full Portfolio

Alchemab operates a platform that identifies novel drug targets and therapeutics by analyzing patient antibody repertoires using deep B cell sequencing and computational analysis of samples from disease-resilient individuals.

AI & Machine LearningBiotechDeep TechHealthtech

JOJane Osbourn(Founder)Young Kwon(Founder)

Co-investorsRARA CapitalSVSV Health InvestorsDCDCVC BioDEDementia Discovery FundLILightstone VenturesBRBritish Business Bank+3 more

Arbor develops programmable DNA editors for genetic medicine, aiming to enable functional cures for patients by addressing genetic diseases through bespoke gene editing approaches.

BiotechDigital HealthMedical DevicesCambridge, US

DADAVID ARTHUR SCOTT(Executive Officer)inWINSTON XIA YAN(Executive Officer)FZFENG ZHANG(Director)Feng Zhang, Ph.D.(Arbor Co-founder and Scientific Advisory Board Chair)DWDavid Walt, Ph.D.(Arbor Co-founder)David Scott, Ph.D.(Arbor Co-founder)

Co-investorsARARCH Venture PartnersGRGreatPoint VenturesILIllumina VenturesTCTCG CrossoverALAlly Bridge GroupJAJanus Henderson Investors+5 more

Casma is a biotech company developing technology that uses the autophagy pathway to degrade disease targets for therapeutic applications.

BiotechDeep TechHealthtechBoston, US

ABAndrea Ballabio(Founder)BLBeth Levine(Founder)Herbert Virgin(Founder)JHJames Hurley(Founder)in

Co-investorsASAstellas Venture Management LLCTHThird Rock VenturesEIEisai Innovation, Inc.THThe Column Group

Immunitas discovers and develops therapeutic antibodies for cancer and autoimmune diseases, with its lead program targeting CD161 for solid tumors and hematological malignancies.

BiotechDigital HealthMedical DevicesWaltham, US

AWAmanda Wagner(CEO)inDan Matloff(Executive Officer)Jiaping Gu(Director)Jeffrey Goldberg(Executive Officer, Director)

BoardLBLaura Brass(Director)inKWKai Wucherpfennig(Director)

Co-investorsAGAgent CapitalDCDC Investment PartnersLILifelinkLOLongwood FundM M VenturesMEMedical Excellence Capital+5 more

Mediartx develops novel therapies for patients with fibrotic diseases.

BiotechMedical DevicesBoston, US

Rahul Ballal, PhD(CEO)PYPaul Yaworsky, PhD(CSO)inRBRahul Ballal(Executive Officer, Director)inBrian Hubbard(Director)Stacey Brenner(Executive Officer)David de Graaf(Director)

Co-investorsAGAgent CapitalGIGimvLOLongwood FundMIMission BiocapitalNONovartis Venture FundPFPfizer Venture Investments+5 more

Mission BioCapital is a venture capital firm that invests in early-stage life science companies, from therapeutics and drug discovery to biotech tools and diagnostics.

BiotechDeep TechSan Francisco, US

BoardDouglas Crawford, PhD(Managing General Partner)Peter Parker(Managing General Partner)

Co-investorsCOConnecticut InnovationsTWTwelve Hundred VC (1200 VC)

Mozart Therapeutics develops protein therapeutics focused on immunology and oncology treatments.

BiotechMedical Devices

MDMark Davis(Scientific Co-Founder)K. Christopher Garcia(Scientific Co-Founder)CKCalvin Kuo(Scientific Co-Founder)KFKatie Fanning(President & Chief Executive Officer)in

Co-investorsARARCH Venture PartnersJDJDRF T1D FundMRMRL Ventures FundPFPfizer Venture InvestmentsSOSofinnova PartnersABAbbVie+7 more

Photys Therapeutics develops bifunctional small-molecule medicines that use induced proximity to recruit kinases and drive targeted protein phosphorylation, aiming to modulate and repair disease-driving proteins.

BiotechHealthtechLongevityWaltham, US

Amit Choudhary(Scientific Founder)DSDavid Steinberg(Chairman & Founding CEO)inEHEdward Holson(Co-founder & CSO)inLNLizzie Ngo(Co-founder)inBrian Fenton(President & CEO)in

Co-investorsLOLongwood FundMPMPM BioImpact8V8VCMRMRL Ventures Fund

Switch Therapeutics develops RNA interference (RNAi) therapeutic applications targeting central nervous system diseases, leveraging research from Caltech, Harvard Medical School, and City of Hope.

AI & Machine LearningBiotechDeep TechMedical DevicesSouth San Francisco, US

Si-Ping Han(Secretary)inDeepshikha Datta(Chief Executive Officer and President)

BoardKevin Zhang(Director)Alicia Irurzun-Lafitte(Director)inDMDylan Morris(Director)in

Co-investorsBOBold Capital PartnersCRCRV (Charles River Ventures)DODolby Family VenturesFRFREEFLOWGLGlobal BrainUPUpfront Ventures+3 more

Monimoit develops cancer therapeutics by combining chemical proteomics, covalent-based molecular technologies, and patient-derived translational insights to target difficult-to-drug cancer-promoting proteins and overcome resistance to existing treatments.

BiotechDeep Tech

Co-investorsTHThe Column Group

Violet Labs builds software tools for engineers designing and building physical products across industries including aerospace, defense, robotics, and energy.

Data & InfrastructureDeveloper ToolsEnterprise SoftwareHardwareSan Francisco, US

LHLucy Hoag(CEO)in

Co-investorsFEFelicis VenturesMAMaC Venture CapitalMAMairs & Power VCV1V1 VCDEDementia Discovery FundHOHopelab+4 more

Violet provides free, personalised support for Australian families navigating end-of-life care, combining human connection and technology to offer practical guidance, emotional support, and tools for important conversations.

Digital HealthFintechHealthtechImpact & Social GoodMental HealthHaymarket, AU

BoardKate Carnell(Chairperson)

Co-investorsTETechstarsDEDementia Discovery FundHOHopelabNONorthwell HoldingsSESemperVirens Venture CapitalTHThe Venture Collective+1 more

Violet provides healthcare organizations with data analytics and tools to measure and improve their ability to deliver person-centered care that considers patients' individual preferences, identities, and experiences.

Data & InfrastructureDigital HealthHealthtechNew York City, US

GCGaurang Choksi(CEO and Founder)inSZScott Zaloom(Head of Operations)inDKDr. Kay Nikiforova(Head of Clinical & Research)inEKEliot Kristan(Head of Engineering)in

Co-investorsGAGaingelsHEHead & Heart CapitalSESeae VenturesSESemperVirens Venture CapitalTHThe Venture CollectiveW W Health Ventures Gp Llc+4 more

Violet provides a unified API for commerce infrastructure that simplifies checkout, catalog management, and order processing for platforms and marketplaces serving multiple merchants.

B2B MarketplacesE-commerceSaaSSeattle, US

BSBrandon Schulz(Founder)inRhen Zabel(Executive Officer, Director, Promoter)Adam Dreiblatt(Director)

Co-investorsALAlumni VenturesSESeaChangeDEDementia Discovery FundHOHopelabNONorthwell HoldingsRERed Sea Ventures+4 more

Violet Therapeutics is a biotechnology company developing small molecule drugs for central nervous system and neurodegenerative diseases, using its C-to-C Engine to map cellular connectivity and signaling in CNS disorders.

AI & Machine LearningBiotechDeep TechCambridge, US

William E Yelle(Executive Officer, Director)Atsushi Usami(Director)Meredith Fisher(Executive Officer, Director)Jonathan Behr(Director)Francisco Quintana(Founder)Darby Schmidt(Chief Scientific Officer)

Co-investorsSVSV Health InvestorsDEDementia DiscoveryDEDementia Discovery FundLILifespan Vision VenturesUTUTEC

United Immunity develops a myeloid-targeting platform using pullulan-based nanoparticles to selectively deliver therapeutic agents and vaccine antigens to macrophages and dendritic cells.

AI & Machine LearningBiotechDigital HealthMedical Devices

Co-investorsNINippon Venture CapitalUTUTECAOAozora Corporate Investment

AIRNA develops genetic medicines that use ADAR, a naturally occurring human protein, to precisely edit RNA and treat genetic diseases without permanently modifying DNA.

AI & Machine LearningBiotechDeep TechHealthtechStanford, US

TSThorsten Stafforst(Chairman of the Board of Directors)inKEKris ElveruminTBTodd Bazemore(Chief Executive Officer)inJin (Billy) Li(Treasurer and Secretary)inPaul Vogel(Chief Executive Officer and President)in

BoardRodger Novak(Chair)in

Co-investors+N+ND CapitalARARCH Venture PartnersFOForbionVEVenrockFAFast Track InitiativeLILifelink+3 more