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Casma Therapeutics

Boston, US · 7 known investors

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Casma is a biotech company developing technology that uses the autophagy pathway to degrade disease targets for therapeutic applications. The company combines molecular biology expertise with a proprietary discovery platform to identify and eliminate disease-causing cellular elements.

BiotechDeep TechHealthtech

Founders & leadership

ABAndrea Ballabio
Andrea BallabioFounder
BLBeth Levine
Beth LevineFounder
HV
Herbert VirginFounder
JHJames Hurley
James HurleyFounderJames Hurley is founder of Casma Therapeutics, a biotech company developing autophagy-based therapeutics to degrade disease targets. His research background encompasses membrane biology, with particular focus on mechanisms relevant to neurodegeneration and viral infection.

Investors · 7

Third Rock Ventures✓ confirmed by Casma TherapeuticsBoston · $100K – $5M

How we know: the company's own site · a partner's Signal profile · globalgenes.org · Not right? Tell us

Eisai Innovation, Inc.listed by Eisai Innovation, Inc.Cambridge · $5M
Ono Venture Investment, Inc.listed by Ono Venture Investment, Inc.South San Francisco

How we know: Ono Venture Investment, Inc.'s portfolio page · Not right? Tell us

The Column GroupreportedSan Francisco · $30M

How we know: a partner's Signal profile · globalgenes.org · Not right? Tell us

Also in the syndicate · 2

Eventide Asset ManagementSchroder Adveq

Funding

SEC filings, press & company announcements

$50M disclosed across 1 of 2 rounds · 2020–2022

Source: company announcements and press reports — follow each round's link for the claim.

Founder mafia

2 people who came through Casma Therapeutics went on to found or lead other companies.

Tim FunnellFounding team: Corporate DevelopmentFounded Ascend Advanced TherapiesNagesh MahanthappaIndependent DirectorFounded Scholar Rock

In the news

Casma Therapeutics Receives MJFF Support to Advance Research on TRPML1 in Parkinson’s Disease - Casma Therapeuticscasmatx.com · Mar 2026

Frequently asked questions

What does Casma Therapeutics do?
Casma is a biotech company developing technology that uses the autophagy pathway to degrade disease targets for therapeutic applications. The company combines molecular biology expertise with a proprietary discovery platform to identify and eliminate disease-causing cellular elements.
Who founded Casma Therapeutics?
Casma Therapeutics was founded by Andrea Ballabio, Beth Levine, Herbert Virgin, James Hurley.
Who are Casma Therapeutics's investors?
Casma Therapeutics's investors include Astellas Venture Management LLC, Third Rock Ventures, Eisai Innovation, Inc., Ono Venture Investment, Inc., The Column Group.
How much funding has Casma Therapeutics raised?
Casma Therapeutics has disclosed $50M raised across 1 of its 2 known rounds.
Where is Casma Therapeutics headquartered?
Casma Therapeutics is headquartered in Boston, US.