Twine Ventures — Full Portfolio

Alaffia invests in and partners with African communities on development projects focused on education, maternal health, and environmental sustainability.

ConsumerImpact & Social Good

OTOlowo-n'djo Tchala(Founder)in

Co-investorsNENew VoicesOSOssian CapitalTRTRANSFORMATION CAPITAL191984 Ventures Management, LlcAPAperture Venture CapitalFIFirstMark Capital+3 more

Alaffia builds AI agents for health plans that automate and support the claims lifecycle, including utilization management, payment integrity, and appeals, by ingesting medical records and cross-referencing clinical facts against a plan's policies.

AI & Machine LearningDigital HealthInsurTech

TATJ Ademiluyi(Founder)in

Co-investorsAPAperture Venture Capital191984 Ventures Management, LlcFIFirstMark CapitalGIGingerbread CapitalRERemarkable VenturesTATAU Ventures+1 more

Alaffia offers Autodor, an AI platform that pre-processes prior authorization requests for health plan utilization management teams by extracting clinical data, applying policy-based logic, and generating human-reviewed case summaries.

AI & Machine LearningDigital HealthHealthtechInsurTech

TATJ Ademiluyi(Cofounder)in

Co-investorsANAnthemis VentureENEntrepreneurs Roundtable Accelerator (ERA)FIFirstMark CapitalGIGingerbread CapitalRERemarkable VenturesTATau Ventures+5 more

Alchemy Health publishes a state-by-state tracker of the federal Rural Health Transformation Program (RHTP), summarizing each state's funding allocation, current and upcoming funding opportunities, and engagement events.

Digital HealthHealthtechMedical DevicesSaaSOklahoma City, US

SSid(Founder & Co-CEO)inSVSid Viswanathan(Founder & Co-CEO)inPPPeter Park(Founder & Co-CEO)inSusie Crowe(Founder & Chief Pharmacist)in

Co-investorsANAndreessen HorowitzSPSpringbank

Alden builds a system of AI agents for home care providers that automate care coordination tasks such as filling shift callouts, monitoring clock in/out and punctuality, and planning matched caregiver rosters.

AI & Machine LearningDigital HealthHealthtech

Rose Huang(Founder)in

Co-investorsEQEquitage Ventures, L.L.C.FLFlare Capital Partners

Palo Alto, US

Lucas Ackerknecht(Founder)Phil Stahlfeld(Founder)

Co-investorsSTStarshotWOWorkshop Venture Partners

Apella provides real-time operating room monitoring and predictive analytics through computer vision and AI integration with EHR systems, helping surgical teams detect delays, optimize scheduling, and improve OR efficiency.

AI & Machine LearningDigital HealthHealthtech

Co-investorsK2K2 HealthVenturesLALayout VenturesOPOPAMP CAPITALCACasdin CapitalHIHighlandXOPOperator Partners+2 more

Ava offers a credit-building app for U.S. consumers, including a Credit Builder Mastercard, a Save & Build Credit secured loan, and rent and utility reporting.

ConsumerFintechSan Francisco, US

OSOmar Sinno(Co-Founder & CEO)inAbdellatif Lawand(Co-Founder & CTO)RRReza Rahman(Co-Founder & President, Growth)inALAbed LawandAbed L(Founder)RSRavneet Singh Khalsa(Founder)in

Co-investorsGRGreylock PartnersSUSure VenturesTRTransform VCWEWestern Technology InvestmentBUBurst Capital

CloudCruise provides an AI-powered platform for building and running browser automations, particularly for healthcare workflows like EHR and payer portal integrations.

AI & Machine LearningEnterprise SoftwareHealthtechSaaSSan Francisco, US

AZAdrian Ziegler(Founder)inFMFelix Martin Eckert(Founder)in

Co-investorsFLFloating PointMEMeridian Street CapitalY Y CombinatorRERefract Ventures

Colla Health provides a behavioral health program for cancer patients, staffing clinicians with psycho-oncology training who deliver evidence-based therapies such as CBT and ACT.

Digital HealthHealthtechMental Health

Beau Palin(Founder)in

Co-investors202048 VenturesCICity LightMEMenlo VenturesONOncology Ventures

Frontier Machines builds FR-1, an AI-powered industrial robot that learns repetitive manual tasks such as packing, bagging, kitting, and assembly at workstations before end-of-line.

Advanced ManufacturingAI & Machine LearningRobotics

Co-investorsSWSwitch Ventures

Fullscript is a clinical platform for healthcare providers to manage supplements, lab ordering, personalized care plans, and patient adherence within their existing EHR workflows.

Digital HealthHealthtechWellness & Fitness

KBKyle Braatz(Founder)in

Co-investorsASAscension VenturesDEDefy PartnersHGHGGCLELeonard GreenALAltas PartnersL L Catterton

San Francisco, US

Uri Pomerantz(Executive Officer, Director)Nicolas S. Bergengruen(Founder)in

BoardDKDan Kimerling(Director)in

Co-investorsANAngel Collective Opportunity FundCLClocktower VenturesDEDeciensPRPrecursor Ventures

Nectar builds a utility intelligence platform that aggregates energy consumption data from utility bills and online portals to help companies optimize their energy usage and costs.

Advanced ManufacturingCleantechClimate TechData & InfrastructureEnergyEnterprise SoftwareSaaSSan Francisco, US

AWAllen Wang(Founder)inKHKatherine He(Founder)in

Co-investorsFOFormus CapitalY Y CombinatorMEMenloMEMenlo VenturesTRTrue Ventures

Oasys provides practice management and AI-powered documentation software for mental health practitioners and clinics.

Digital HealthMental HealthSaaSSan Francisco, US

Co-investorsBEBetter Ventures Central LlcPAPathlight Ventures191984 Ventures Management, LlcBEBetter Ventures

Oasys is a gaming-focused blockchain built by gaming industry veterans, designed with user experience at its core through features like zero gas fees and fast transaction finality.

Crypto & Web3Deep TechGaming

Co-investorsCECeras VenturesDIDigital Finance GroupFEFenbushi CapitalHYHyperithmNONonagonSESerafund+5 more

Pikl is developing staffing technology, described by the company as still in a pre-launch phase.

HR TechSaaSDenver, US

KHKarson Humiston(CEO and Director)in

BoardMorgan Blumberg(Director)

Co-investorsCOColle Capital PartnersSESeedrs

Plover is a specialty insurance broker that uses software to quantify exposures, recommend products, and market renewals, helping insurance agents place hard-to-place accounts in the P&C space.

FintechInsurTechSaaSNew York City, US

RSRanajay Sen(Founder)inTommy Peeples(Founder)Max Clarke(Executive Officer, Director)Sen Ranajay(Executive Officer, Director)

San Francisco, US

Yibo Ling(Founder)

Co-investorsSASarah SmithTHThirdstream PartnersGRGradient Ventures

A platform that enables healthcare providers to order, track, and receive lab test results from multiple laboratory companies through a single dashboard, supporting both in-person and telehealth patients with flexible billing options and EHR integration.

Digital HealthHealthtechSaaSSan Francisco, US

TVTara Viswanathan(Founder)inRHRosa Hamalainen(Founder)inBEBen Easton(Founder)in

Co-investors3C3cubed VenturesBEBessemer Venture PartnersHUHustle FundJAJames Beshara FundMAMantis CapitalNENeythri Futures Fund+5 more

Teiko provides CLIA-validated high-dimensional cytometry services—including spectral flow and mass cytometry panels, blood preservation kits, gating, and a data analysis dashboard—for immune cell profiling in clinical trials.

BiotechDigital HealthHealthtechSalt Lake City, US

RSRamji Srinivasan(Executive Officer, Director)inMatt(Co-founder)inMatthew Spitzer(Director)

BoardVWVictor Wang(Director)in

Co-investorsCICivilization Ventures Management, LlcHAHAWKTAILHOHOF CapitalTATau VenturesWEWestern Technology Investment

Verse provides a faster path to grid power for data centers, helping AI infrastructure companies and large energy users bypass interconnection queue delays to come online sooner.

AI & Machine LearningCleantechEnergy

SHSeyed H. Madaeni, Ph.D.(Founder)in

Co-investorsBEBessemer Venture PartnersCICIVCOCoatue ManagementGVGV (Google Ventures)INInnovacomSUSupernova Invest

Waymark builds an AI-powered clinic model for Medicaid populations, using predictive analytics and clinical decision support to identify at-risk patients and coordinate community-based care.

AI & Machine LearningDigital HealthHealthtechSan Francisco, US

AAAfia Asamoah(Co-Founder and Head of People and Legal)inSBSanjay Basu(Co-Founder and Head of Clinical)inRBRajaie Batniji(Co-Founder and CEO)inRBRajaie Batniji MD DPhil(Founder)inSanjay Basu, MD, PhD(Founder)inKelly Coffin(Executive Officer, Director, Promoter)

Co-investorsACAcumen AmericaANAndreessen HorowitzCVCVS Health VenturesLULux CapitalNENew Enterprise Associates (NEA)

Zipline is a data infrastructure platform built on the open-source Chronon project that lets engineering teams build, deploy, and monitor real-time data pipelines, features, and embeddings for AI agents and ML models.

AI & Machine LearningData & InfrastructureDeveloper ToolsUnion City, US

Nikhil Simha Raprolu(Executive Officer, Director, Promoter)NSNikhil Simha(Co-Founder & CTO)inVZVarant Zanoyan(Co-Founder & CEO)inPNPiyush Narang(Chief Architect)in

BoardCZChris Zeoli(Director)in

Co-investorsWIWingANAndreessen HorowitzBABaillie GiffordFIFidelity InvestmentsGOGoldman SachsGVGV (Google Ventures)+6 more