Route 66 Ventures — Full Portfolio

Switchboard Health provides software that modernizes the specialty care referral process, using data sets, a virtual care network, and matching algorithms to connect patients with specialty care options.

AI & Machine LearningDigital HealthHealthtechSaaSBoise, US

Derek Baird(CEO)in

BoardBenjamin E. B. Britt(Director)inJonathan Phillips(Director)

Board seatBen BrittArif SorathiaRyan Katz· per SEC Form D

Co-investorsHeadwater VenturesCapital ElevenFirst Trust Capital Partners

AccessPay provides a cloud-based bank integration platform that connects ERP, payroll, and back-office systems to banks to automate payments, collections, and bank statement retrieval.

Enterprise SoftwareFintechSaaS

Co-investorsAccel-KKRBeringeaBeringea ProVen VCT

HealthtechChicago, US

Inna Plumb(Executive Officer, Director)Matt Hallgren(Executive Officer)

BoardArif Sorathia(Director)inWilliam Sheahan(Director)Todd Johnson(Director)Patricia Morehead(Director)

Co-investorsCity LightDigiTx Partners LLC

Bunker Insurance provides commercial insurance for small businesses, freelancers, and independent professionals, offering tailored policies and usage-based insurance (UBI) with short-term coverage matching contract lengths.

FintechFuture of WorkInsurTech

Co-investorsClocktower VenturesComcast VenturesLaunchCapitalAmerican Family VenturesOmidyar Network

Change Foods uses precision fermentation with microbes to produce real dairy proteins, fats, and flavors without cows, then applies traditional cheesemaking techniques to make animal-free cheese that tastes, stretches, and melts like conventional dairy cheese.

BiotechClimate TechFoodTechPalo Alto, US

David Bucca(Executive Officer, Director, Promoter)

Co-investorsAngelCentralBetter Bite VenturesBlue Horizon CorporationClear Current CapitalGGFGreen Generation Fund

Clearmatics builds protocols and platforms for decentralised markets, drawing on distributed systems, cryptography, consensus protocols, economic mechanism design, and decentralised finance.

Crypto & Web3Deep TechFintech

Co-investorsNycaNyca Partners

Insurance comparison (AngelPad #2).

Keith Moore(Founder)in

Co-investorsAngelPadBlumberg CapitalBullpen CapitalCore Venture CapitalRRE Ventures

Omaha, US

William Fisher(Executive Officer, Director)Merri Wees(Executive Officer)Mark Vipond(Executive Officer, Director)

BoardBen Britt(Director)inAlex Hart(Director)Matthew Lawlor(Director)

Co-investorsFinch Capital

DriveWealth offers an API-based Brokerage-as-a-Service platform that lets banks, broker-dealers, asset managers, digital wallet providers, and consumer brands embed securities trading and investing for their end clients.

Developer ToolsEnterprise SoftwareFintechSaaSJersey City, US

Robert Cortright(Executive Officer, Director)Michael Dugan(Executive Officer, Director)

Co-investorsAccelMiddlegame VenturesMouro CapitalPoint72 VenturesRaptor GroupSenaHill Partners+1 more

EarthOptics measures soil health for farmers and landowners using field sensors and lab analysis to assess soil's physical, chemical, and biological properties.

AgTechAI & Machine LearningClimate TechData & InfrastructureDeep TechArlington, US

Lars Dyrud(CEO)inTodd Martin(Executive Officer)inStephanie Landa(Executive Officer)Hunt Bowers(Executive Officer)inAdam Gerson(Executive Officer)John Dombrosky(Executive Officer, Director)

Co-investorsArgonautic VenturesCerity Partners VenturesDoon CapitaliSelect FundMiddleland CapitalS2G Investments+6 more

Flume Health provides AI-powered solutions for healthcare insurance operations, including tools for claims processing, care management, underwriting, and regulatory compliance automation.

AI & Machine LearningHealthtechInsurTechScarsdale, US

Cedric Kovacs-Johnson(Executive Officer, Director)

Co-investorsCrosslink CapitalEntrepreneurs Roundtable Accelerator (ERA)Founder CollectiveOptum VenturesRemarkable VenturesBlumberg Capital+2 more

Hydrogen is a modular, no-code platform for embedded finance that lets companies build and offer financial products and services.

Developer ToolsEnterprise SoftwareFintechSaaS

Matthew Kane(CEO)

Co-investorsFlucas VenturesVU Venture PartnersSixThirty Ventures

Inflow is an app-based program providing personalized coaching, strategies, and tools to help people with ADHD manage their condition.

BiotechConsumerDigital HealthHealthtechMental HealthSaaSLondon, GB

Levi Epstein(Founder)inSeb Isaacs(Founder)in

Co-investorsOctopus VenturesY Combinator

Infrascale provides cloud-based data protection with backup and disaster recovery solutions, offering offsite data storage and standby infrastructure for real-time recovery.

Cloud ComputingCybersecurityData & InfrastructureEnterprise SoftwareEl Segundo, US

KENNETH SHAW, JR.(Executive Officer, Director)Ken ShawKEN SHAW, JR.(Executive Officer, Director)KEN SHAW(Director)MICHAEL BELL(Executive Officer)HARDY PARUNGAO(Executive Officer)

Co-investorsCarrick Capital PartnersMontage Capital

Joon is a mobile app that turns daily tasks and routines into a game where children care for a virtual pet by completing parent-assigned "Quests," aimed at helping kids build habits, focus, and life skills.

ConsumerDigital HealthEdTechOakland, US

Isaac Eaves(Founder)

Co-investorsBlue Lion GlobalCathexis VenturesBrickyard

Judopay operates a payments platform that connects businesses to acquirers, open banking services, fraud tools and alternative payment methods across mobile, web and in-app.

FintechSaaS

Wellness & FitnessNew York City, US

Aaron Albert(Executive Officer, Director)Mark Groves(Executive Officer)Matthew Sadofsky(Director)

BoardJeff Cantalupo(Director)

Co-investorsSocial StartsTechstarsAble PartnersJoyance PartnersListen VenturesWndrCo

Moneyfarm offers a DIY "Share Investing" service and app that lets retail investors build their own portfolios from UK stocks, ETFs, bonds, and mutual funds, alongside managed portfolio options and research tools including an AI information support tool called Bastian.

FintechSaaSLondon, GB

Co-investorsUnited VenturesEndeavor Catalyst

Rockville, US

Al Noshirvani(Executive Officer, Director)John Cramp(Executive Officer, Director)Pascal Bouvier(Director)Tim Bender(Executive Officer)Ali Noshirvani(Executive Officer, Director)Richard Caro(Director)

Co-investorsEscalate Capital PartnersEdison PartnersSWaN & Legend Venture Partners

Co-investorsAnthemis Venture

Co-investorsFrancisco PartnersIA Capital GroupOak HC/FTVermont Center for Emerging Technologies (VCET)

Ordaōs uses AI and deep learning through its Design Engine to design novel mini-proteins and protein binders such as nanobodies for drug discovery.

AI & Machine LearningBiotechDeep TechNew York, US

David Longo(Co-Founder & Chief Executive Officer)inMatthias Denecke(Chief Technology Officer)inVictor Bustos(VP of Pre-clinical R&D)inScott Horner(Director)

BoardBenjamin Britt(Director)inUlo Palm(Director)

Co-investorsCitta CapitalIAG Capital PartnersMiddleland Capital

Parsley Health delivers evidence-based, whole-body functional medicine care through board-certified clinicians trained in functional medicine.

Digital HealthHealthtechWellness & FitnessNew York, US

Robin Berzin(Founder & CEO)Robin Berzin MD(Founder)in

Co-investors7wire VenturesAdvance Venture PartnersAlpha EdisonAmplo VenturesCorewell Health VenturesEvolution VC Partners+10 more

Payzer builds an all-in-one software platform for trade contractors covering payments, financing, and business operations from initial customer contact through final payment.

Construction TechEnterprise SoftwareFintechSaaSCharlotte, US

Joe Giordano(Founder)inDouglas Little(Executive Officer)Joseph A Giordano(Executive Officer, Director)Thomas McCulley(Director)Mark E McDowell(Director)THomas McCulley(Director)

Co-investorsAlerion VenturesElevate Innovation PartnersGray VenturesGrotech VenturesIDEA Fund PartnersCharlotte Fund

Quantemplate is a network platform that enables organizations to exchange, reconcile, and orchestrate data across value chains with transparency and trust.

AI & Machine LearningData & InfrastructureEnterprise SoftwareFintechInsurTechSaaSNew York City, US

Adrian Rands(Director)Daniel Dall'Asta(Director)Caroline Murphy(Executive Officer)Howard Lundgren(Executive Officer, Director)

Co-investorsBallpark VenturesTechstars

Reframe Financial helps families prepare for the financial issues of aging, with a focus on long-term care and caregiving costs.

FintechHealthtechInsurTech

Karan Aneja(CEO & Co-Founder)

Co-investorsAlpha EdisonAV8 VenturesJ-VenturesSixThirty Ventures

Ripple builds blockchain-based financial infrastructure to enable cross-border value transfer and payment solutions for enterprises, governments, and financial institutions.

Crypto & Web3Enterprise SoftwareFintechSan Francisco, US

Ryan Fugger(Founder)David Schwartz(Director)inSusan Athey(Director)Gene Sperling(Director)Christian Larsen(Executive Officer, Director, Promoter)Young Guo(Director)

Co-investors500 GlobalAbstract VenturesAurum Venture PartnersAvant Global LLCCamp One VenturesCastle Island Ventures+19 more

Ryse Health is a digital care platform for individuals and families managing type 2 diabetes, combining medical support from endocrinologists and behavioral health specialists with technology, coaching, and community resources.

Digital HealthHealthtechWashington, US

Richard Gurley(Executive Officer, Director, Promoter)Erin Kane(Executive Officer, Director, Promoter)

BoardPankaj Jethwani(Director)Eric Dobosh(Director)inRyan Tyner(Director)

Co-investorsW Health Ventures Gp Llc

Sensorium Therapeutics is a clinical-stage biotech company developing novel CNS therapies for anxiety, epilepsy, and cognitive dysfunction using its SensAI platform, which integrates AI, chemistry, and curated natural product data to identify therapeutic patterns from over 50 million biological relationships.

AI & Machine LearningBiotechDigital HealthMedford, US

Jerrold Rosenbaum(Director)inJacob Hooker(Executive Officer, Director)inPranav Tadi(Executive Officer)

BoardRyan Katz(Director)inKevin Lalande(Director)inRichard Simon(Director)

Co-investorsBonaventure Equity, LLCHatteras Venture PartnersIter InvestmentsMission BiocapitalService Provider CapitalSante Health Ventures

Simplesurance develops technology that enables businesses to embed insurance products into their offerings.

FintechInsurTechSaaS

Co-investorsAllianz XGerman Startups GroupLA ROCA CapitalRheingau FoundersTempoCapODDO BHF+1 more

Income-based student financing platform helping higher education institutions offer flexible and personalized financing models.

Co-investorsTFX Capital

Yuvo Health provides software and business services to help community health centers operate more effectively within value-based care models.

Digital HealthEnterprise SoftwareHealthtechSaaSNew York, US

Cesar Herrera(Chief Executive Officer and Co-Founder)inJanel Sia(Chief Strategy Officer and Co-Founder)Stephanie Hudson(Executive Officer, Director)

BoardFatima Husain(Director)inBrenton Fargnoli(Director)inJoseph Mayer(Director)in

Co-investorsAlleyCorpAV8 VenturesGreyMatterHLM Venture PartnersLifeX VenturesMastry+3 more