Gilgamesh Pharmaceuticals
YC S20 ↗New York City, US · Founded 2019 · Delaware corporation · 15 employees · 10 known investors
Gilgamesh Pharmaceutical develops novel chemical entities for psychiatric disorders using medicinal chemistry and AI-powered translational platforms to design rapid-acting therapies targeting neurobiological mechanisms rather than symptom management. The company's pipeline spans depression, anxiety, addiction, and schizophrenia, with programs validated by AbbVie's acquisition of its first asset and partnerships with Columbia University and the National Institute on Drug Abuse.
AI & Machine LearningBiotechDigital HealthHealthtechTherapeuticsPsychedelicsMental Healthin /gilgamesh-pharmaceuticals/@GilgameshRXycombinator.com ↗
Founders & leadership· Y Combinator alumni (S20)
JS
Jonathan SporninFounder
AK
Andrew KruegelinFounder
DS
Dalibor SamesinFounder
JS
JONATHAN SPORNinFounder
TK
Thomas Kevin Murphy, Ph.D.Executive Officer
AK
Andrew Kruegel, Ph.D.Executive Officer
JS
Jonathan Sporn, M.D.President and Chief Executive Officer
Investors · 10
Aera VCSingapore · $25K – $5M
Frontera Technology VenturesTexas
Frontier Path VCLondon
James Beshara FundLos Angelesvia James J Beshara · inferred
JLSNew York
Magnetic VenturesBoston · $1M – $6M
NoeticToronto, Ontario
Prime Movers LabJackson · $2M – $30Mvia Gaetano Crupi · board
PsyMed VenturesBerkeley
Y CombinatorSan Francisco · $500K
Reported raises · per SEC filings
Form D private placements▶$13.8MraisedMay 2022 · 14 investors · PharmaceuticalsRule 506(c)
▶$13.8MraisedMay 2022 · 14 investors · Pharmaceuticals
Rule 506(c)Officers, directors & promoters on the filing
- Robert BermanDirector
- Gerard MarekExecutive Officer
- Phil SkolnickDirector
- Jonathan SpornExecutive Officer, Director
- Yoni FalksonExecutive Officer
- Thomas Kevin MurphyExecutive Officer
- Andrew KruegelExecutive Officer, Director
- Gaetano CrupiDirector
- Laszlo KissExecutive Officer
- Amy KruseDirector
- Offering amount
- $50M
- Amount sold
- $13.8M
- Minimum investment
- $50K
- First sale
- May 2022
- Incorporated
- Corporation, Delaware, 2019
- Federal exemptions
- 06c
▶$951offeredFeb 2022 · 1 investors · PharmaceuticalsRule 506(b)
▶$951offeredFeb 2022 · 1 investors · Pharmaceuticals
Rule 506(b)Officers, directors & promoters on the filing
- Robert BermanDirector
- Phil SkolnickDirector
- Amy KruseDirector
- Andrew KruegelExecutive Officer, Director
- Jonathan SpornExecutive Officer, Director
- Offering amount
- $951
- Minimum investment
- $951
- First sale
- Feb 2022
- Incorporated
- Corporation, Delaware, 2019
- Federal exemptions
- 06b
▶$34.7MraisedMay 2021 · 66 investors · PharmaceuticalsRule 506(b)
▶$34.7MraisedMay 2021 · 66 investors · Pharmaceuticals
Rule 506(b)Officers, directors & promoters on the filing
- Andrew KruegelExecutive Officer, Director
- Amy KruseDirector
- Robert BermanDirector
- Dalibor SamesDirector
- Jonathan SpornExecutive Officer, Director
- Offering amount
- $34.7M
- Amount sold
- $34.7M
- Minimum investment
- $10K
- Proceeds to insiders
- $630K
- First sale
- Apr 2021
- Incorporated
- Corporation, Delaware, 2019
- Federal exemptions
- 06b
▶$735KraisedSep 2020 · 10 investors · PharmaceuticalsRule 506(b)
▶$735KraisedSep 2020 · 10 investors · Pharmaceuticals
Rule 506(b)Officers, directors & promoters on the filing
- Dalibor SamesDirector
- Andrew KruegelDirector
- Jonathan SpornExecutive Officer, Director
- Amount sold
- $735K
- Minimum investment
- $10K
- First sale
- Aug 2020
- Incorporated
- Corporation, Delaware, 2019
- Federal exemptions
- 06b
▶$150KraisedJul 2020 · 1 investors · PharmaceuticalsRule 506(b)
▶$150KraisedJul 2020 · 1 investors · Pharmaceuticals
Rule 506(b)Officers, directors & promoters on the filing
- Jonathan Sporn, M.D.Executive Officer, Director
- Andrew Kruegel, Ph.D.Executive Officer
- Thomas Kevin Murphy, Ph.D.Executive Officer
- Offering amount
- $150K
- Amount sold
- $150K
- Minimum investment
- $150K
- First sale
- Jul 2020
- Incorporated
- Corporation, Delaware, 2019
- Federal exemptions
- 06b
▶$2.4MraisedJul 2020 · 25 investors · PharmaceuticalsRule 506(b)
▶$2.4MraisedJul 2020 · 25 investors · Pharmaceuticals
Rule 506(b)Officers, directors & promoters on the filing
- Thomas Kevin Murphy, Ph.D.Executive Officer
- Andrew Kruegel, Ph.D.Executive Officer
- Jonathan Sporn, M.D.Executive Officer, Director
- Amount sold
- $2.4M
- First sale
- Apr 2020
- Incorporated
- Corporation, Delaware, 2019
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
In the news
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- Fierce Biotech Fundraising Tracker '26: AdvanCell adds $315M; Draig draws down $65Mfiercebiotech.com · 2026
- Sell or Invest in Gilgamesh Pharma Stock Pre-IPOnasdaqprivatemarket.com · 2026
- Gilgamesh Pharma Closes Oversubscribed $60 Million Series A to Develop Next Generation Neuropsychiatric Therapiesprnewswire.com · 2026
- AbbVie inks $1.2B deal to buy Gilgamesh's psychedelic programfiercebiotech.com · 2025
- Gilgamesh raises funds to advance treatments for mental healthpharmaceutical-business-review.com · 2022
- Gilgamesh Pharmaceuticals Raises $39 Million Series B to Advance Mental Health Treatmentsprnewswire.com · 2022
- The Y Combinator Startup Raising Millions to Develop a New Psychedelic Drugsbusinessinsider.com · 2022
