/Investor DB

Clarus Ventures — Full Portfolio

22 tracked investments · listed companies and verified rows first

Calcimedicacalcimedica.comin𝕏NASDAQ: CALCApr 2016SEC filingmedium confidence

CalciMedica is a clinical-stage biopharmaceutical company developing CRAC (calcium release-activated calcium) channel inhibition therapies for serious acute and chronic inflammatory, immunologic, and cardiopulmonary diseases.

BiotechHealthtechLa Jolla, US

Kenneth A. Stauderman(Co-founder)inGonul Velicelebi(Co-founder)Daniel Geffken(Executive Officer)A. Rachel Leheny(Executive Officer, Director)Michael J. Dunn(Executive Officer)inStephen Bardin(Chief Financial Officer)in

Board seatEmmett Cunningham· per SEC Form D · $80.4M raise · filed Jun 2018

Co-investorsAisling CapitalMESA VERDE VENTURE PARTNERSRevelation PartnersSanderling VenturesClarus LifesciencesOrbiMed

Praxispraxismedicines.comin𝕏NASDAQ: PRAXOct 2016SEC filingmedium confidence

Praxis Precision Medicines is a central nervous system precision neuroscience biopharmaceutical company developing therapies for CNS disorders characterized by neuronal excitation-inhibition imbalance, with a pipeline spanning movement disorders and epilepsy.

BiotechDeep TechHealthtechBoston, US

Steve Petrou(Co-Founder, President of Research & Development)inKiran Reddy(Executive Officer, Director)inMarcio Souza(President & Chief Executive Officer)in

Board seatNicholas GalakatosNicholas G. Galakatos· per SEC Form D · $10M raise · filed Jun 2019

Co-investorsAvoro Capital AdvisorsCapria VenturesOCV PartnersAlameda ResearchAPOLLO PROJECTSBlackstone+6 more

Annexonannexonbio.comin𝕏Dec 2018SEC filingmedium confidence

Annexon Bio develops early complement inhibitors that target C1q, the initiating molecule of the classical complement pathway, to treat autoimmune, neurodegenerative, and ophthalmic diseases.

BiotechHealthtechSo. San Francisco, US

Ben Barres(Scientific Co-Founder)Douglas Love(Founder)inMark L Smith(Executive Officer)Campbell Murray(Director)inThomas Wiggans(Director)Ricky Sun(Director)

Board seatEmmett Cunningham· per SEC Form D · $85M raise · filed Dec 2018

Co-investorsBain Capital Life SciencesCorrelation VenturesNew Enterprise Associates (NEA)BlackRockBlackstone Life SciencesDeerfield Management Company+2 more

Catabasis PharmaceuticalsinMar 2015SEC filingmedium confidence

BiotechCambridge, US

Jill C. Milne(Executive Officer, Director)inIan Sanderson(Executive Officer)in

BoardRon Laufer(Director)Jean George(Director)Michael Ross(Director)

Board seatNicholas Galakatos· per SEC Form D · $20.4M raise · filed Mar 2015

Co-investorsLightstone Ventures

Flowonix MedicalinJun 2016

HealthtechMt Olive, US

Louis Altieri(Executive Officer)Larry Heaton(Executive Officer)in

BoardSteven C. Adler(Director)David Jenkins(Director)Donald P. Carson(Director)

Board seatKurt Wheeler· per SEC Form D

Tectonic Therapeutictectonictx.cominJul 2016SEC filingmedium confidence

Tectonic is a clinical-stage biotechnology company developing therapeutic proteins and antibodies that target G-Protein Coupled Receptors (GPCRs) using a proprietary platform called GEODe™.

AI & Machine LearningBiotechMedical DevicesWatertown, US

Timothy A. Springer(Co-Founder)Andrew C. Kruse(Director)Alise Reicin(Executive Officer, Director)inDaniel Lochner(Executive Officer)Marc Schwabish(Executive Officer)inPeter McNamara(Executive Officer)in

Board seatScott Requadt· per SEC Form D · $25M raise · filed Aug 2016

Co-investorsEcoR1 CapitalVida VenturesAlly Bridge GroupPolaris PartnersSoleus Capital

Venus Conceptvenusconcept.comin𝕏May 2015SEC filingmedium confidence

Venus develops non-invasive, energy-based medical aesthetic devices for body, face, skin, and hair treatments, integrating robotics, AI, and IoT technologies.

BiotechHardwareHealthtechMedical DevicesToronto, US

Domenic Serafino(Executive Officer, Director)inKirk Gunhus(Executive Officer)inRoss Portaro(Executive Officer)inAnna Georgiadis(Executive Officer)inMelissa Kang(Executive Officer)inMichael Mandarello(Executive Officer)in

Board seatEmmett CunninghamEmmett Cunningham, Jr.· per SEC Form D · $26M raise · filed Aug 2017

Co-investorsAPERTURE Venture PartnersEssex Woodlands Healthcare PartnersLongitude CapitalHealthQuest Capital

Abcuroabcuro.comSeries C · Feb 2025 · $200M

Abcuro develops therapies that target highly cytotoxic T cells for autoimmune diseases, including its lead candidate ulviprubart for inclusion body myositis.

BiotechHealthtechNewton, US

Steven A. Greenberg(Chief Scientific Advisor & Co-Founder)Steven A. Greenberg, MD(Chief Scientific Advisor & Co-Founder)John Alexander Martin(Executive Officer, Director)Stefano Gulla(Founder)Evan Thompson(Executive Officer)David de Graaf(Executive Officer, Director)

Co-investorsBain Capital Life SciencesNew Enterprise Associates (NEA)RA CapitalSamsara BioCapitalSanofi VenturesMass General Brigham Ventures+9 more

Cleave Biosciencescleavetherapeutics.com

BiotechBurlingame, US

Mark Rolfe(Executive Officer)Laura Shawver(Executive Officer, Director)inTimothy Smith(Executive Officer)

BoardAlfred Scheidegger(Director)inPeter Thompson(Director)inCarol Gallagher(Director)in

Co-investorsAstellas Venture Management LLCNew Enterprise Associates (NEA)Nextech InvestOUP (Osage University Partners)5AM VenturesOrbiMed+2 more

FerroKin BiosciencesinFeb 2012acquired by Shire

Developed a next-generation iron chelator for iron overload in transfusion-dependent anemia; acquired by Shire in 2012.

BiotechSan Carlos, US

Hugh Y. Rienhoff, Jr., M.D.(Executive Officer, Director)in

BoardMarten Steen(Director)inDennis Henner, Ph.D.(Director)Bryant E. Fong(Director)

Co-investorsHealthCapMC Healthcare Ventures

Forty Seven Incfortyseveninc.comin𝕏Oct 2017acquired by Gilead · Mar 2020

Gilead discovers, develops, and delivers therapeutic medicines for life-threatening diseases, with focus on virology, oncology, and inflammation across 35+ countries.

BiotechHealthtechMedical DevicesPalo Alto, US

Ravindra Majeti(Director)Irving Weissman(Director)Eric Jensen(Executive Officer)

BoardChristopher Schaepe(Director)inJeffrey Bird(Director)Dennis Henner(Director)

Co-investorsBluebird VenturesGV (Google Ventures)Lightspeed Venture PartnersSofinnova VenturesSutter Hill VenturesWellington Management

Imagoimagobio.comin𝕏acquired by Merck

A pharmaceutical company that develops medicines and vaccines, with research pipelines and clinical trials aimed at new treatments.

BiotechHealthtech

Co-investorsFrazier Life SciencesHighlight CapitalMRL Ventures FundXeraya CapitalAmgen VenturesBlackRock+5 more

Lumos Pharmalumos-pharma.comin𝕏Apr 2016

Lumos Pharma is a clinical-stage biopharmaceutical company developing therapies for rare diseases, with a lead candidate targeting Pediatric Growth Hormone Deficiency.

BiotechHealthtechAustin, US

Richard John Hawkins(Executive Officer, Director)John C. McKew(President and Chief Scientific Officer)inPisit "Duke" Pitukcheewanont(Chief Medical Officer)inLori Lawley(Chief Financial Officer)inBrad Powers(Chief Compliance Officer and General Counsel)inCampbell Murray(Executive Chairman)in

Co-investorsNew Enterprise Associates (NEA)Deerfield Management CompanySante Health VenturesSante VenturesWellcome Trust

Ophthotechophthotech.comOct 2018 · $30M

BiotechNew York, US

David Guyer(Executive Officer, Director)Glenn Sblendorio(Executive Officer, Director)Mike AtiehinDavid Redlick(Director)Keith Westby(Executive Officer)David Carroll(Executive Officer)

Co-investorsSofinnova VenturesSV Health InvestorsSV Life Sciences

Revelle Aestheticsrevelleaesthetics.cominNov 2021 · $50M

Revelle Aesthetics develops and commercializes the Avéli device, a precision medical technology for cellulite reduction.

FemTechHealthtechMedical DevicesMountain View, US

Eb Bright(Co-Founder and Chief Administrative Officer)inJonathan Podmore(Co-Founder and Chief Technology Officer)inJoshua Makower(Director)Earl A. Bright II(Director)Caroline Van Hove(Executive Officer, Director)in

BoardPhilippe Schaison(Director)in

Co-investorsNew Enterprise Associates (NEA)Runway Growth CapitalWindham Capital Partners

Tagworks Pharmaceuticalstagworkspharma.comin𝕏Series A · Jun 2023 · $65M

Tagworks Pharmaceuticals develops cancer therapies using its Click-to-Release platform, a chemical reaction that activates antibody-drug conjugates (ADCs), masked immunomodulators, and other prodrugs on-target while deactivating radioimmunotherapies off-target.

BiotechHealthtechMedical DevicesNijmegen, NL

Co-investorsBifLightstone VenturesNew Enterprise Associates (NEA)Novartis Venture FundYsios CapitalGilde Healthcare+1 more

VBI Vaccinesvbivaccines.comin𝕏Defunct

VBI Vaccines is a biopharmaceutical company developing vaccine candidates using virus-like particle (VLP) platforms, including proprietary enveloped VLP and mRNA-launched eVLP technologies.

BiotechHealthtechCambridge, US

Marc Kirchmeier(Vice President, Formulation Development)Egidio Nascimento(Chief Financial Officer)inDavid Anderson(Senior Vice President, Research)inJeff Baxter(President and Chief Executive Officer)inAdam T. Buckley(Vice President, Business Development)inMurray G. Smith(Executive Officer)

Co-investors5AM VenturesARCH Venture PartnersK2 HealthVentures

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

ESSA PharmaSilk TechnologiesVBI Vaccines Inc/BCImago BioSciences, Inc.Lycera

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.