🦊/Investors

Signet Healthcare PartnersFull Portfolio

61 tracked investments · listed companies and verified rows first

Ligandligand.comin𝕏NASDAQ: LGNDJan 2016

Ligand is a royalty aggregator that finances late-stage clinical development and commercialization programs for biopharmaceutical companies.

BiotechFintechLa Jolla, US

Brook Byers(Co-founder)inMATTHEW W. FOEHR(Director)JOHN L. HIGGINS(Executive Officer, Director)inMATTHEW KORENBERG(Director)inCHARLES S. BERKMAN(Director)inTodd Davis(Chief Executive Officer)in

Co-investorsSofinnova VenturesVenrock

TELA Biotelabio.comin𝕏NASDAQ: TELA

Offers soft tissue repair solutions combining naturally sourced tissue with polymer; lead product OviTex for hernia repair (NASDAQ: TELA), based in Malvern, PA.

BiotechMalvern, US

Antony Koblish(Founder)inFrancis Conway(Executive Officer)Maarten Persenaire(Executive Officer)Christine Arasin(Executive Officer)

BoardKevin Rakin(Director)inAshley Freidman(Director)

Co-investorsCheckmate Capital Group LLCEssex Woodlands Healthcare PartnersHighCape CapitalOrbiMed1315 CapitalRTW Investments L.P.

Ascendiapharmaascendiapharma.cominJun 2025

Ascendia Pharmaceutical Solutions is a contract development and manufacturing organization (CDMO) that provides formulation, nanotechnology, and manufacturing services for pharmaceutical and biological companies from pre-formulation through commercialization.

Advanced ManufacturingBiotechHealthtechMedical DevicesNorth Brunswick, US

Jingjun Huang(Executive Officer, Director)

BoardRobert Bloder(Director)Michael Bogda(Director)inShoufeng Li(Director)Theron Odlaug(Director)

Board seatJames Gale· per SEC Form D

Cerium Pharmaceuticalsceriumpharma.cominJul 2021SEC filingmedium confidence

Cerium Pharmaceuticals develops and commercializes medicines for rare or "orphan" diseases, including kidney disease.

BiotechHealthtechGaithersburg, US

Gregg Lapointe(Co-Founder & Chief Executive Officer)inRobert J. Rubin(Co-Founder & Interim CMO)Nancy Klett(Co-Founder & Chief Operating Officer)inŞemsi Burak Derkunt(Chief Scientific Officer)inBrian Schreiber(Chief Medical Officer (2015 to 2021))inPeter Collum(Director)

Board seatJames Gale· per SEC Form D · $10.1M raise · filed Jul 2021

Gynesonicsgynesonics.comin𝕏Dec 2021acquired by HologicSEC filingmedium confidence

FemTechHealthtechMedical DevicesRedwood City, US

Christopher Owens(Executive Officer, Director)Darrin Uecker(Executive Officer, Director)

BoardKen Haas(Director)Jonathan MacQuitty(Director)inMike Carusi(Director)inDoug Fisher(Director)

Board seatJoyce Erony· per SEC Form D · $50M raise · filed Dec 2021

Co-investorsAmzak HealthBain Capital Life SciencesEndeavour VisionFemHealth VenturesKaiser Permanente VenturesKluz Ventures+5 more

Icon Bioscienceiconbioscience.comin𝕏Nov 2015

Icon Bioscience develops biodegradable, sustained-release intraocular ophthalmic products using its proprietary Verisome drug delivery technology, targeting unmet needs in inflammation, glaucoma, and retinal disease treatment.

BiotechHealthtechMedical DevicesSunnyvale, US

David Tierney(Executive Officer, Director)in

BoardSong Toja(Director)William White(Director)Michael Hemric(Director)

Board seatJoyce Erony· per SEC Form D

Impulse Dynamicsimpulse-dynamics.comin𝕏Dec 2020SEC filingmedium confidence

Impulse Dynamics develops implantable medical device technology for cardiac care, with a background in biomedical research and implantable cardiac electronics.

BiotechHardwareHealthtechMedical DevicesDublin 2, US

Shlomo Ben-Haim(Director)Jason Spees(Chief Executive Officer)inPaul Bae(Chief Administrative Officer and General Counsel)inDavid Prutchi(Executive Vice President, Chief Technology Officer)inRichard J. Buchholz(Chief Financial Officer)Anthony Hong(Chief Science and Strategy Officer)in

Board seatJoyce Erony· per SEC Form D · $60M raise · filed Jan 2021

Co-investorsAmzak HealthAlgerBraidwellEssex Woodlands Healthcare PartnersREDMILESands Capital Ventures

Neuros Medicalneurosmedical.comOct 2020SEC filingmedium confidence

Neuros Medical develops the Altius Direct Electrical Nerve Stimulation System, an FDA-approved implantable device that delivers patient-controlled electrical stimulation to treat chronic post-amputation pain in adult lower limb amputees.

BiotechHealthtechMedical DevicesAliso Viejo, US

David Veino(President and CEO)Zach Stassen(Chief Financial Officer)Robert J. Centa(Chief Financial Officer)Jon J. Snyder(Director, President, Secretary and CEO)in

BoardWilliam Harrington(Director)

Board seatJoyce Erony· per SEC Form D · $42.8M raise · filed Nov 2020

Co-investorsAmzak HealthAPERTURE Venture PartnersCWRU Technology VenturesiSelect FundJobsOhio VenturesJumpstart Ventures+5 more

Advantice Healthadvanticehealth.comin

Advantice is a collective of skin care brands offering science-backed dermatological and wellness products for consumers seeking healthier skin.

ConsumerHealthtechWellness & Fitness

Hellen Spanjer(Head of Innovation)in

Co-investorsTA AssociatesRoundTable Healthcare Partners

Alpexalpex.com

Alpex is a research-based pharmaceutical company that develops and manufactures pharmaceutical and nutraceutical products, offering an end-to-end platform covering R&D, formulation, clinical trials, product registration, manufacturing, and global export.

Advanced ManufacturingBiotechHealthtech

Altasciencesaltasciences.comin

Altasciences operates a drug development platform that integrates nonclinical research, bioanalysis, manufacturing, and Phase I/II clinical execution to compress early-stage drug development timelines from industry standards of 27–51 months to as little as 18 months.

BiotechDeep TechEnterprise SoftwareHealthtechMedical DevicesLaval, CA

Marie-Hélène Raigneau(Chief Executive Officer)inCatherine Konidas(Chief Administrative Officer)inDr. Beatrice Setnik(Chief Scientific Officer)Dr. Gaetano Morelli(Executive Vice President Medical Affairs, Chief Medical Officer)Steve Mason(Co-Chief Operating Officer)inRobert Sabelli(Co-Chief Operating Officer)in

Co-investorsNovo HoldingsKilmer Group

Amarinamarincorp.comin𝕏

Amarin Corporation is a cardiovascular health pharmaceutical company developing treatments to prevent cardiovascular disease.

BiotechHealthtechMedical Devices

Co-investorsAvoro Capital AdvisorsFountain Healthcare PartnersLongitude CapitalSofinnova Ventures

Amriglobalamriglobal.comin

Curia is a CDMO (Contract Development and Manufacturing Organization) providing drug discovery, development, and manufacturing services across small molecules, generic APIs, sterile drug products, and biologics for biopharma companies.

BiotechEnterprise Software

Anteisanteis.comin

Merz Aesthetics, Anteis SA develops and manufactures biomedical products for aesthetic medicine, including injectable fillers, resorbable implants, and skin hydration gels.

Medical DevicesPlan-les-Ouates, CH

Apicoreapicore.comSep 2016

BiotechSomerset, US

Vithal Dhaduk(Director)Albert Friesen(Executive Officer, Director)Ravishanker Kovi(Executive Officer, Director)in

BoardTheron E. Odlaug(Director)James Gale(Executive Officer)Todd Sone(Director)

Arborpharmaarborpharma.comin𝕏acquired by Azurity Pharmaceuticals

Azurity Pharmaceuticals develops and commercializes innovative medicines across 10 therapeutic areas for overlooked patient populations, serving over 50 countries with a portfolio of more than 50 medicines across various dosage forms.

AI & Machine LearningBiotechDigital HealthHealthtechWoburn, US

Avantiumavantium.comin𝕏

Avantium develops bio-based materials and polymer technologies, including PEF and other renewable alternatives to conventional plastics, serving the packaging and materials industry.

BiotechCircular EconomyCleantechNew MaterialsNetherlands, NL

Co-investorsNavitas CapitalAster CapitalCapricorn Venture PartnersNV NOMPMVSofinnova Partners+2 more

Biojectbioject.com

An online store selling human growth hormone (HGH) injections, peptides, and related products such as Zptropin, Genotropin, Somatropin, Semaglutide, and Ozempic, marketed for bodybuilding, fat loss, and anti-aging.

ConsumerE-commerce

Bionpharmabionpharma.comDec 2015

Bionpharma researches, develops, and manufactures generic prescription drugs and over-the-counter products, and is one of the largest US suppliers of softgel capsules.

BiotechHealthtechPrinceton, US

Gaurav Mehrotra(Executive Officer)inVenkatachalam Krishnan(Executive Officer, Director)Lavesh Samtani(Executive Officer)

BoardJames Gale(Director)Carol S. Ben-Maimon(Director)Richard Van Duyne(Director)

Cangenecangene.comin𝕏

Emergent is a public health company that develops and manufactures medical countermeasures and protective solutions for endemic public health threats, national security preparedness, and supports biopharma innovators and organizations with manufacturing.

BiotechMedical Devices

Chr Olesenchr-olesen.dkin

Chr.

Advanced ManufacturingFoodTechLogistics & Supply ChainDenmark, DK

Corerxcorerxpharma.com

BiotechClearwater, US

TODD R DAVIAU(Executive Officer, Director, Promoter)MARK J LICARDE(Executive Officer, Director, Promoter)BRIAN MCMILLAN(Executive Officer, Director, Promoter)

BoardRONALD L MILLER(Director, Promoter)

Curidacurida.noinApr 2024

Curida is a contract manufacturing organization specializing in pharmaceutical liquid formulations and biologics, operating under strict EU GMP and ISO certifications to ensure product quality and compliance.

Advanced ManufacturingBiotechDeep TechMedical DevicesNorway, NO

Co-investorsCanicaInvestinor

Direvodirevo.com

The site presents itself as combining biomass technology with sports-betting infrastructure in Vietnam, but its content is dominated by promotional posts and links for online gambling and card-game platforms (e.g.

Gaming

Elanelan.comin𝕏acquired by Perrigo

Perrigo manufactures and distributes branded and private label self-care products including over 13,000 stock keeping units across multiple categories, serving consumers through retailers, pharmacies, and e-commerce channels in the United States, Europe, and other major markets.

ConsumerDirect to ConsumerHealthtechWellness & FitnessPerrigo, Michigan (implied by company name, though not explicitly stated on this page), US

Luther Perrigo

Co-investorsPAG Japan

Endoendo.comin

Keenova is a specialty therapeutics company focused on rare, stigmatized, or unaddressed conditions across areas including immunology, urology, hepatology, ophthalmology, orthopedics, and critical care.

BiotechHealthtechMedical DevicesMalvern, US

Blaise Coleman(President; Chief Executive Officer)inMatthew Maletta(Executive Vice President; Chief Legal Officer; Secretary)inFrank Raciti(Vice President; Controller; Chief Accounting Officer)inMark Bradley(Executive Vice President; Chief Financial Officer)inScott Hirsch(Director)Paul Efron(Director)

Epix Therapeuticsinacquired by Medtronic · Jan 2019 · $316M

Medtronic designs and develops medical technology for treating complex diseases.

AI & Machine LearningDigital HealthHealthtechMedical Devices

Co-investors8VCCWRU Technology VenturesElevate VenturesMenlo VenturesOak Investment PartnersPfizer Venture Investments+5 more

Ertert.comin𝕏

Clario provides endpoint technologies and software for clinical trial management, serving pharmaceutical and biotech sponsors, CROs, and clinical trial sites globally.

AI & Machine LearningHealthtechMedical Devices

Co-investorsAlpine MeridianGenstar

Flerieflerie.com

Flerie invests in and builds companies working on pharmaceutical and biotech projects or adjacent capabilities, using its network, expertise, and resources to support their growth.

BiotechHealthtech

Fluxionfluxionbio.cominacquired by Cell Microsystems

BiotechDeep TechHardware

Co-investorsClaremont Creek VenturesMission Bay CapitalMission Biocapital

Gbibiogbibio.comin

GBI Biomanufacturing manufactures stem cells for regenerative medicine applications, including treatments for orthopedic injuries, wound care, and arthritic conditions.

BiotechDeep TechHealthtechMedical DevicesFlorida, US

Jesse McCool(President)in

BoardKarl Pinto(Chair of the Board of Directors)

Gi Supplygi-supply.comin𝕏acquired by Laborie

Laborie provides medical devices and diagnostic equipment for gastroenterology, serving healthcare professionals who treat gastrointestinal conditions.

HealthtechMedical Devices

Junopharmjunopharm.ca

Juno Pharma Canada Inc. is a pharmaceutical company formed in April 2025 through the merger of Juno Pharmaceuticals Corp. and Omega Laboratories Limited.

BiotechMontreal, CA

Laxailaxai.com

LAXAI Life Sciences is a Contract Research, Development, and Manufacturing Organization (CRDMO) offering small molecule R&D, custom synthesis, process development, scale-up, and manufacturing of specialty chemicals, intermediates, and APIs.

Advanced ManufacturingBiotechHealthtech

Vamsi Maddipatla(Chairman and Managing Director)

Leadingpharmaleadingpharma.com

Leading Pharma develops, manufactures, and distributes generic pharmaceutical products in oral solid dosage forms across multiple therapeutic areas from a U.S.-based, FDA-approved facility.

Advanced ManufacturingBiotechHealthtech

Leon Nanodrugsleon-nanodrugs.comin

Leon develops nanoparticle-based drug delivery systems for therapeutic applications in healthcare.

Advanced ManufacturingBiotechDeep TechMedical DevicesPlanegg, DE

Dr. Wolfgang Hofmann(Chief Executive Officer)Dr. Blerina Shkodra(Chief Scientific Officer)Dr. Matthias Schumacher(Chief Technology Officer)in

Co-investorsLBBW Venture Capital GmbH

Mallinckrodtmallinckrodt.cominAcquired

Following a 2025 merger of Mallinckrodt and Endo, the combined business separated into two companies: Keenova Therapeutics, which develops treatments for rare, stigmatized, or unaddressed conditions across areas such as immunology, urology, hepatology, ophthalmology, orthopedics, and critical care; and Par Health, which produces generics, sterile injectables, and active pharmaceutical ingredients backed by a U.S.-based manufacturing network.

Advanced ManufacturingBiotechHealthtechMedical Devices

Co-investorsARCH Venture PartnersCross Creek AdvisorsPfizer Venture InvestmentsSofinnova Ventures

Optiscan Biomedicaloptiscancorp.comin

Dowds is a UK-based engineering company providing integrated technical solutions and design-led project delivery for complex built environments, with particular expertise in healthcare infrastructure, mechanical, electrical, and building systems integration.

Construction TechHealthtechUK, GB

Co-investorsAscension VenturesBioBrit

PainTEQpainteq.cominAug 2025

PainTEQ develops medical devices and implants for sacroiliac joint dysfunction, offering solutions ranging from biologicalbone allografts to titanium implants as alternatives to injections or fusion surgery.

Deep TechHealthtechMedical DevicesTampa, US

Shanth(Chief Executive Officer)

Co-investorsWindham Capital Partners

Paragonix Technologiesparagonixtechnologies.comin𝕏Mar 2023 · $24M

Paragonix Technologies develops, manufactures, and services organ preservation devices that combine cooling techniques with digital tracking and monitoring for clinicians managing donor organs during transplantation.

HardwareHealthtechMedical DevicesCambridge, US

DeWitt Davenport(Director)John Cammett(Director)Carl Rickenbaugh(Director)Alexander Arrow(Director)John McDermott(Director)Lisa Anderson(Executive Officer, Director)

Pfenexpfenex.comin𝕏

Pfenex provides a Pseudomonas fluorescens-based microbial expression platform for manufacturing recombinant proteins, antibodies, and biologics at scale.

Advanced ManufacturingBiotechDeep Tech

Pharm Intpharm-int.comin

A contract drug manufacturing organization (CDMO) specializing in complex pharmaceutical formulations and potent compounds, serving drugmakers from small batches through full-scale production.

Advanced ManufacturingBiotechMedical DevicesHunt Valley, US

Rkpharmaincrkpharmainc.com

RK Pharma Inc is a US-based generic pharmaceutical group that develops, manufactures, and sells generic drugs, active pharmaceutical ingredients, and injectable, sterile ophthalmic, and dermal products, with a focus on formulation-challenged and first-generic opportunities.

Advanced ManufacturingBiotechEnterprise SoftwareHealthtechNew Jersey, US

Nailesh Bhatt(Founder and CEO of VGYAAN Pharmaceuticals)

Sanciliosancilio.comin𝕏

Sancilio & Company provides guidance and regulatory support to early-stage biopharmaceutical entrepreneurs on compliance, manufacturing, and funding strategy.

BiotechRiviera Beach, US

Frederick Sancilio(Executive Officer, Director)inDaren Graham(Executive Officer)Andrew Folmer(Executive Officer)Stephen Porter(Executive Officer)

BoardDennis Langer(Director)Patrick Gray(Director)

Smartmedsyssmartmedsys.com

SmartMedSys develops G-EYE, a colonoscopy technology that improves polyp removal efficiency and adenoma detection compared to standard procedures.

HealthtechMedical DevicesRa'anana, IL

Teambestteambest.comin

Designs and manufactures medical imaging and particle therapy equipment for cancer treatment and diagnostic visualization.

BiotechDeep TechDigital HealthHardwareHealthtechMedical DevicesSpringfield, US

Krishnan Suthanthiran(Founder and President)in

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Pharmaceutics InternationalArgostherapeuticsClarislifesciencesHydrolixImpopharmaKewincMolecularmedNorthX BiologicsNxbioOctoplusPharmanobisRK PharmaSpepharmTeligentVigenebio

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.