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Mike Carusi
InvestorManaging Partner at Lightstone Ventures
Menlo Park, CA
Writes $100K – $5M checks · typically $1.5M
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About
Mike Carusi is a life science investor at Lightstone Ventures (LSV), a biotech and medtech venture firm founded in 2012 with offices in the U.S. and Ireland. He has previously invested through ATV and Morgenthaler, and has been involved in a number of medical device and biopharmaceutical companies across his career. His portfolio and deal history span both medtech and biotech, including companies that were acquired or went public such as Ardian (acquired by Medtronic), MicroVention (acquired by Terumo), PowerVision (acquired by Alcon) and Plexxikon (acquired by Daiichi Sankyo). He currently leads investments in companies including Allay Therapeutics, Cala Health, Shoulder Innovations and Tallac Therapeutics.
Contact· published on Mike's own website
Invests in
BiotechHealthtechMedical Devices
Deals · 3
Shoulder InnovationsBoard seat
via Lightstone Ventures · filed Mar 2025 · $40.1M raise
GynesonicsBoard seat
via Lightstone Ventures · filed Jan 2019 · $77M raise
NuvairaBoard seat
via Lightstone Ventures · filed May 2018 · $8M raise
Attribution from SEC filings, press coverage, and firm rosters.
Other disclosed investments
Led
Allay TherapeuticsApreo HealthArdianCala HealthEndoGastric SolutionsMediSix TherapeuticsMicroVentionPlexxikonPowervisionShoulder Innovations, Inc.Tallac Therapeutics
Investor
Allay TherapeuticsAltura MedicalArdianEndoGastric SolutionsGI DynamicsNeuroVistaPowervisionSecond GenomeTrotana Therapeutics
Sources: the investor's own website · SEC Form D filings · curated public sources.
Colleagues at Lightstone Ventures
Network2
Investors connected to Mike in public investor directories — a warm-intro map.
Frequently asked questions
- Who is Mike Carusi?
- Mike Carusi is a life science investor at Lightstone Ventures (LSV), a biotech and medtech venture firm founded in 2012 with offices in the U.S. and Ireland. He has previously invested through ATV and Morgenthaler, and has been involved in a number of medical device and biopharmaceutical companies across his career. His portfolio and deal history span both medtech and biotech, including companies that were acquired or went public such as Ardian (acquired by Medtronic), MicroVention (acquired by Terumo), PowerVision (acquired by Alcon) and Plexxikon (acquired by Daiichi Sankyo). He currently leads investments in companies including Allay Therapeutics, Cala Health, Shoulder Innovations and Tallac Therapeutics.
- Where does Mike Carusi work?
- Mike Carusi is Managing Partner at Lightstone Ventures.
- What does Mike Carusi invest in?
- Mike Carusi invests in Biotech, Healthtech, Medical Devices.
- What check size does Mike Carusi write?
- Mike Carusi typically writes checks of $100K – $5M.
- What boards does Mike Carusi sit on?
- Mike Carusi holds tracked board seats at Gynesonics, Nuvaira, Shoulder Innovations.
- What companies has Mike Carusi invested in?
- Investments tracked here include Allay Therapeutics, Apreo Health, Ardian, Cala Health, EndoGastric Solutions, Gynesonics, MediSix Therapeutics, MicroVention, Plexxikon, Powervision, Shoulder Innovations, Inc., Tallac Therapeutics, and 11 more.
- Does Mike Carusi lead rounds?
- Yes — Mike Carusi has led 12 tracked investments.
About this profile. Compiled from public sources — Lightstone Ventures's own website, regulatory filings and public professional profiles — and summarised by Fundraising Fox; every fact is kept with where it came from. Spotted an error, or would rather not be listed? Email privacy@fundraisingfox.com · How we build profiles · Your rights