OpenSky Ventures — Full Portfolio

TRIANA Biomedicines is a venture-backed biopharmaceutical company developing small-molecule "molecular glue" therapeutics that induce protein:protein interactions to degrade or alter disease-causing target proteins, with an initial focus on targeted protein degradation for cancer.

BiotechDeep TechHealthtechLexington, US

PTPatrick Trojer(President & Chief Executive Officer)in

Board seatJoshua Resnick· per SEC Form D · $120.1M raise · filed Dec 2025

Co-investorsASAscenta CapitalATAtlas VentureLILightspeed Venture PartnersRARA CapitalBEBessemer Venture PartnersPFPfizer Ventures+3 more

DAASH combines multiple research panels, social and advertising signals, and product attribute data to model sales performance, market share, and emerging trends for consumer brands.

AI & Machine LearningData & InfrastructureMarketing TechRetail Tech

Melissa Munnerlyn(CMO)inPSPhilip Smolin(CEO)inJustin Stewart(CTO)in

Co-investorsBUBullpen CapitalENEntrepreneur VenturesGFGFT VenturesHYHypothesisNENew Stack VenturesRERed Bike Capital+2 more

Agentic AI code-based visualization tool

Cohesive is building a work platform where people and AI work together in a shared space.

AI & Machine LearningFuture of WorkSaaS

KZKevin Z.(Founder)inNNNathan Nguyen(Founder)inARAlec Rubin(Founder)inJoey Vadala(Founder)inNSNate Saletan(Founder)in

Co-investorsCOColle Capital PartnersOVOverline

Daash Intelligence runs an AI-based predictive commerce intelligence platform for beauty and personal care retail brands.

San Francisco, US

PSPhilip Smolin(Executive Officer, Director)inKim Perell(Executive Officer, Director)

BoardRKRoss Kimbel(Director)in

Co-investorsBUBullpen CapitalGFGFT VenturesNENew Stack VenturesRERed Bike CapitalSISilicon Road VenturesWIWillow Growth Partners

Dimension provides a tech-enabled platform to simplify waste management for companies of any size through customizable, on-demand pickup and disposal services managed via an online interface.

AI & Machine LearningB2B MarketplacesCircular EconomyCleantechClimate TechEnterprise SoftwareLogistics & Supply ChainSaaS

Lily Danqi SheninLumin Chen

Co-investors50500 GlobalALAlumni VenturesMOModerne VenturesHPHPS Investment Partners, LLCLOLombardstreet VenturesLOLong Run Capital+1 more

Dimension provides software and full-service support for brands, agencies, and creators selling on TikTok Shop, helping manage shops and grow GMV.

Creator EconomyE-commerceSaaS

Co-investorsUPUpScaleX

Fishwife is a direct-to-consumer brand that sells curated tinned fish products and related merchandise.

ConsumerDirect to ConsumerFoodTechCalifornia, US

Becca Millstein Caroline Goldfarb(Founder)

Co-investorsASAssembled BrandsEVEverywhere VenturesFIFifth Down CapitalMUMultifaceted CapitalVAVan Wickle Ventures

Nomadica offers customizable wine bundles featuring ready-to-drink canned wine in various varieties such as white, red, rosé, and flavored options.

ConsumerDirect to ConsumerE-commerceFoodTech

Kristin O(Founder)

Co-investorsGAGaingelsINInvestBevSISimple Food Ventures

Feel is a direct-to-consumer beauty and wellness brand that offers nutritional supplements, including collagen, vitamins, and targeted health products.

ConsumerDirect to ConsumerHealthtechWellness & Fitness

Co-investorsBTBtomorrow VenturesFUFuel VenturesSUSuperAngel.FundTATA Ventures

Hydration+ is a powdered electrolyte drink mix formulated with 1,100mg of electrolytes, vitamins, and plant-based ingredients designed to support hydration, energy, and mental clarity.

ConsumerDirect to ConsumerHealthtechWellness & FitnessLos Angeles, US

Brian Wong(Cofounder)Dustin Bourbaba(Executive Officer, Director)

BoardChris Protasewich(Director)

Co-investorsADAdapt VenturesCHCHVCSUSuperAngel.FundTATA Ventures

Gumshoe is an AI visibility platform that monitors how AI search tools recommend products and discuss brands, enabling marketers to understand and influence brand perception across major AI models.

AI & Machine LearningMarketing TechSaaSSeattle, US

TSTodd Sawicki(Co-founder)inPOPatrick O'Donnell(Co-founder)in

Co-investorsASAscend Venture CapitalGHGHARAGE VenturesHAHawke VenturesPIPioneer Square Labs

Premium hummus for health conscious consumers

Haven provides full-stack accounting services for high-growth businesses and startups, including bookkeeping, business tax preparation, R&D tax credit support, invoicing/accounts receivable, and bill pay/accounts payable workflows.

FintechSaaS

Co-investorsALAlumni VenturesFJFjor FoundersHUHustle Fund

Intro is an online marketplace that enables users to book video consultations with in-demand experts across various fields such as interior design and entrepreneurship.

B2B MarketplacesConsumerMarketplaces

RMRaad Michael Mobrem(Founder)inRaad Mobrem(Founder)

Co-investorsANAndreessen HorowitzCOComcast VenturesCRCrosscut VenturesGAGaingelsJ1J17 CapitalLALakeside Capital+11 more

Kirra makes canned iced teas lightly sweetened with organic juice and no added sugar or artificial sweeteners, using fewer than five ingredients in recyclable cans.

ConsumerDirect to ConsumerWellness & Fitness

Jerrod Clancy(Co-founder)

Levanta operates an affiliate marketing platform connecting marketplace sellers with creators.

AdTechCreator EconomyMarketing TechSaaSSeattle, US

IBIan Brodie(Founder)inRob Schab(Director)

BoardSpencer McKenney(Director)LCLarry Cheng(Director)in

Co-investorsVOVolition CapitalLOLong Run Capital

Limelight is a B2B influencer marketing platform that lets brands find, partner with, and book ad placements across creators (newsletters, LinkedIn, YouTube, and other channels) and track campaign performance through real-time analytics.

AdTechCreator EconomyMarketing Tech

DWDavid Walsh(Founder and CEO)in

Co-investorsASAscend Venture CapitalCOCOREangelsENEntrepreneur VenturesMAMassMutual VenturesSOSoma CapitalASAscend+1 more

Magic Mind produces a line of clinically-formulated mental performance drinks and sleep supplements containing ingredients like Lion's Mane, Bacopa Monnieri, and L-Theanine to support focus, cognition, and sustained energy.

ConsumerWellness & FitnessLos Angeles, US

WHWilliam Hicks(Founder)inJBJames Beshara(Founder)in

Co-investorsBFBFG PartnersFLFloodgateJAJAZZ Venture PartnersJUJude GomilaLILitquidity VenturesMIMidnight+4 more

Mantle provides a business operations platform for app developers and businesses, offering billing, payment pages, analytics, email marketing, and integrations with tools like Stripe and Shopify.

Creator EconomyFintechSaaS

Co-investorsKIKillick Capital1111.2 CapitalCOCorazon CapitalCRCraft VenturesENEniac VenturesFOFoundation Capital+3 more

Max Retail is a retail technology platform that enables independent retailers to convert excess inventory into cash by connecting them directly with shoppers.

B2B MarketplacesE-commerceLogistics & Supply ChainMarketplacesRetail TechSaaSNorth Palm Beach, US

MVMelodie van der Baan(Co-Founder & CEO)inMBMorgan Bodstrom(Co-Founder & CHRO)inDCDamon Ciarelli(Co-Founder & R&D Lead)in

Co-investorsINInterplay Ventures Early Stage Management LlcM1M13OVOverlineRERethink ImpactSTStand Up VenturesTETechstars+3 more

Mixlab is a veterinary pharmacy providing compounded, commercial, and over-the-counter medications for animals across all 50 states.

AI & Machine LearningE-commerceHealthtechNew York, US

Frederic Dijols(Executive Officer, Director)Edward Kim(Director)

BoardDr. Zay Satchu(Co-founder & Chief Veterinary Officer)

Co-investorsEAEastward Capital PartnersESEscalate Capital PartnersJOJoyance PartnersLALakehouse Venture PartnersPAPartners ResolutePLPLUS Capital+8 more

Orka makes a caffeinated flavored water with zero sugar, zero calories, and no juice, positioned as an energy drink alternative.

ConsumerDirect to ConsumerFoodTech

OuterSignal is a customer intelligence platform for eCommerce and DTC brands that enriches customer data to identify VIPs, influencers, and B2B leads within a store's existing order data.

AI & Machine LearningE-commerceMarketing TechSaaSWilmington, US

NSNoah Sanborn Friedman(Co-founder)inZZZach Z.(Founder)inZZZach Zelner(CEO & Co-founder)

Co-investorsBABAM VenturesSHSharf Ventures

Reactiv is a Shopify-native platform that enables ecommerce brands to build mobile commerce applications with native integrations across marketing, merchandising, orders, loyalty, support, and data infrastructure.

Developer ToolsE-commerceRetail TechSaaS

RossZackMike

Co-investorsBOBonfire VenturesRERedbud VCRORolling Fun GP

Reactiv provides a managed platform for Shopify brands to launch and operate mobile commerce experiences, including native apps and no-download App Clips, without requiring internal development resources.

E-commerceRetail TechSaaS

Ross(Founder)Zack(Founder)Mike(Founder)

Co-investorsUNUnbounded CapitalALAlumni VenturesANAnthemis VentureBOBonfire Ventures

Sett makes nicotine-alternative pouches built around Ceretine, a proprietary synthetic alkaloid combined with L-theanine, intended to provide nicotine-like focus and mood effects with fewer downsides.

ConsumerDirect to ConsumerWellness & Fitness

MWMatt Wan(Founder)in

Co-investorsBRBreak Trail VenturesF2F2 Venture CapitalJAJAZZ Venture PartnersLILitquidity VenturesSEService Provider CapitalBEBessemer Venture Partners+2 more

Sett offers an AI platform that helps game studios accelerate content creation from concept to finished product, reducing time spent in development cycles and planning phases.

AdTechAI & Machine LearningGaming

Amit Carmi(Founder)Yoni Blumenfeld(Founder)

Co-investorsBEBessemer Venture PartnersGRGreenfield PartnersJAJAZZ Venture PartnersSASaga VenturesVGvgamesF2F2 Venture Capital

Shoplift is an A/B testing and conversion rate optimization platform for Shopify Plus stores that organizes related tests into campaigns grouped by shared business objectives.

E-commerceRetail TechSaaS

AGAustin Goldman(Founder)inJason Boit(Founder)in

Co-investorsNWNW Angel

Shipsidekick provides a logistics platform combining warehouse management, order management, transportation management, and ERP functions, with an AI assistant, for shippers and third-party logistics providers (3PLs).

AI & Machine LearningLogistics & Supply ChainSaaS

Co-investorsMUMute VenturesCOColumbia Lake PartnersDEDevelopment Bank of WalesMSMS&AD VenturesOCOctopus VenturesPAPact VC+2 more

Siena is an AI customer experience platform for consumer and ecommerce brands, providing AI agents that handle support, shopping recommendations, social media engagement, post-purchase workflows, and subscription management across customer channels.

AI & Machine LearningE-commerceSaaS

LPLisa Popovici(Founder)inAndrei Negrau(Founder)

Co-investorsAGAglae VenturesGAGapMinderSISierra VenturesSUSuperangelSUSuperAngel.FundTHThe Council+1 more

Stanify provides an AI platform for enterprise brands to manage social media comments and DMs, automatically moderating toxic content, drafting on-brand replies, and routing messages to support, sales, or legal teams.

AI & Machine LearningMarketing TechSaaS

HLHank Leber(Founder)inHSHassan Salahuddin(Founder)in

Co-investorsALAllied Venture PartnersENEntrepreneur VenturesINIncisive Ventures

Las Vegas, US

Joshua Resnick(Executive Officer, Director)Rosie O'Neill(Director)BGBrian Garrett(Executive Officer)inFiona Revic(Executive Officer)inSLScott LaPorta(Executive Officer, Director)in

BoardPaul L Kessler(Director)

Co-investorsHAHalogen Ventures Management Company LlcMOMontage CapitalGRGreat Hill Partners

Sunny Within makes clean liposomal dietary supplements formulated with organic avocado oil for longevity, immune support, and cellular health.

Direct to ConsumerLongevityWellness & Fitness

Upwage builds an AI-powered job marketplace that uses AI interviewing agents to reduce bias and increase fairness in hiring for jobseekers, employers, and workers displaced by AI.

AI & Machine LearningEnterprise SoftwareFuture of WorkHR TechPowell, US

DTDiana Tsai(Founder)inGCGreg Call(Founder)inSLSantiago Leon(Product Manager and Founding Member)inNBNate Babbel(CTO and Founding Member)inEMElliot Manson(Head of Marketing and Founding Member)in

BoardTBTanya Beja(Director)in

Co-investorsALAlleyCorpBBBBG VenturesBLBloomberg BetaCOCore Venture CapitalJ4J4 VenturesMOMoai Capital+4 more

Veracity Health develops a metabolic health product that targets cellular energy metabolism to support sustainable weight loss and overall health benefits.

ConsumerDirect to ConsumerHealthtechWellness & Fitness

AEAllie Egan(Founder)inGFGabrielle Francis(Chief Medical Officer)

Co-investors3737 AngelsCACartan CapitalCOCoalition OperatorsGRGreat Oaks Venture CapitalMAMaveronMEMelitas Ventures Llc+8 more

Windmill designs smart, easy-to-install window air conditioners and other home air-care products, including air purifiers, air filters, and smart fans, built on three generations of HVAC industry experience.

CleantechConsumerDirect to ConsumerHardwareIoT

Ryan Figlia(Founder)inDanny Mayer(Founder)in

Co-investorsASAssembled BrandsCOConsumer VenturesCOCosmic Venture PartnersDODot CapitalINInspired CapitalNENext Play Ventures+6 more