O2h Ventures
Venture capitalCambridge · Pre-Seed–Series A · 23 people tracked
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- Sunil Shah233 people can intro you
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Investment thesis
o2h Ventures focuses on early-stage UK biotech and therapeutics companies, targeting disease areas such as cancer and neuroscience where small innovative biotechs supply new ideas to large pharma. The fund leverages AI to make sense of vast biological datasets and improve predictions on research resource allocation. It draws on grassroots relationships in the biotech community and its proprietary 2.7-acre Mill SciTech Park to incubate life science companies. Structured as an S/EIS-compliant vehicle, it offers UK taxpayers income, inheritance, and capital gains tax reliefs, aiming to widen the investor community supporting early-stage research in the UK.
Source: firm website, verified Sep 27, 2026.
Team · 23 people
from the firm's websiteWhat they invest in
from 16 of 16 portfolio companiesBiotech ×14Deep Tech ×6Medical Devices ×6AI & Machine Learning ×5Healthtech ×5Digital Health ×2Mental Health ×2Enterprise Software ×1
HQs:United Kingdom×8Canada×1India×1Singapore×1
Investments · 16 tracked
founders shown can be your intro pathBy year:2026 · 12025 · 12024 · 22023 · 32022 · 12021 · 12018 · 110 dated
Helus Pharma is a clinical-stage biopharmaceutical company developing small-molecule therapies for psychiatric and CNS conditions such as depression, anxiety, schizophrenia, and bipolar disorder.
BiotechDigital HealthHealthtechMental HealthToronto, CA
Eric So(Co-Founder, Executive Chairman)inJohn Kanakis(Co-Founder)inPaul Glavine(Co-Founder and Chief Growth Officer)inGabriel Fahel(Executive Officer)Douglas Drysdale(Executive Officer)Jacqueline Poriadjian(Executive Officer)
Co-investorsInnovating CapitalJLSNoetic
Exonate is a biotechnology company developing treatments for retinal vascular diseases, with a lead asset (EXN407) intended as a topical therapy for diabetic retinopathy and diabetic macular oedema.
BiotechDigital HealthHealthtechMedical Devices
Olav Hellebø(Chief Executive Officer)in
Co-investorsWellcome TrustWren CapitalCambridge Angels groupEMV CapitalMartlet CapitalStoic VC+1 more
Metrion Biosciences provides ion channel screening and drug discovery services for pharmaceutical and biotech companies.
BiotechDeep TechMedical DevicesCambridge, GB
Marc Rogers(Founding Director)inJohn Ford(Founding Director)inKeith McCullagh(Founding Director)inLee Patterson(Chief Executive Officer)in
Co-investorsGresham House VenturesMaven Capital Partners
Stratosvir develops engineered viral immunotherapy treatments for advanced cancers, including prostate cancer, using modified viruses to activate the body's immune system against tumors.
AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesStevenage, GB
Dr Chris Ullman(CEO)inAntonio Postigo(CSO)in
BoardPriya Mande(Chairman)in
Co-investorsDeep Science Ventures
Atelerix develops hypothermic hydrogel encapsulation technology that stabilises and preserves fresh cells, tissues, and blood at room temperature, eliminating the need for cryopreservation and cold-chain logistics.
BiotechMedical DevicesNew Materials
Steve Swioklo(Founder)in
Co-investorsCambridge Angels groupFuture Planet CapitalOxford Technology ManagementUK Innovation & Science Seed Fund
Enedra analyzes tumor evolution patterns by decoding convergent genomic signatures from cancer genomic data.
AI & Machine LearningBiotechMedical Devices
Co-investorsDeep Science VenturesKU Leuven Research & Development
The Financial Ombudsman Service is a free, statutory body set up by UK Parliament in 2001 to investigate and resolve complaints between consumers and financial businesses such as banks, insurers, and pension and investment providers.
FintechGovTechLegalTech
Co-investorsDeepbridge CapitalForce Over Mass CapitalFuel VenturesOxfordQVenturesSeneca Partners+1 more
Five Alarm Bio develops pharmaceutical compounds targeting a novel aging mechanism to prevent and treat age-related chronic diseases.
BiotechLongevity
William Bains(Founding scientist)in
Co-investorsCambridge Angels groupSyndicateRoom
BiotechDundee, Scotland
Timothy Jason Sparey(Executive Officer)Antoine Boulanger(Executive Officer)Francisca Peixoto(Executive Officer)Christopher Andrew Woodland(Executive Officer, Director)
BoardMary Canning(Executive Officer)
Co-investorsEpidarex Capital
Pencil is an AI operating system for marketing that aggregates multiple AI models (from OpenAI, Google, Adobe, Runway, and Bria) into one orchestration layer with enterprise governance controls.
AI & Machine LearningEnterprise SoftwareMarketing TechSingapore, SG
Will Hanschell(CEO)inSumukh Avadhani(CTO)in
Co-investorsBrandtech VenturesEntrepreneur FirstWavemaker PartnersArtesianCatapult VenturesMartlet Capital+6 more
PharmEnable applies AI to small molecule drug discovery, focusing on challenging and data-sparse biological targets that traditional methods struggle to address.
AI & Machine LearningBiotechDeep Tech
Hannah Sore(Founder)in
Co-investorsCambridge Angels groupMartlet CapitalMC Healthcare VenturesDiamond Edge VenturesParkwalk AdvisorsWren Capital
PhoreMost is a biotechnology company developing small molecule drugs and targeted protein degradation therapeutics for cancers with high unmet clinical need, with a lead program (PMC-001) for primary and metastatic brain cancers in Phase 1/2a clinical evaluation.
BiotechMedical DevicesCambridge, GB
Co-investorsAmadeus Capital PartnersAstellas Venture Management LLCCambridge Angels groupUniversity of Cambridge EnterpriseAmadeus Capital SAParkwalk Advisors
Helus Pharma is a clinical-stage pharmaceutical company developing novel serotonergic agonists—synthetic molecules that activate serotonin pathways—as next-generation mental health therapies.
BiotechHealthtechMental HealthLondon
Eric So(Co-Founder, Executive Chairman)Carol Routledge(Executive Officer)George Tziras(Director)Khalid Howladar(Director)Marie Claire Layzell(Executive Officer, Director)Peter Rands(Executive Officer, Director)
Spirea develops a multivalent ADC linker technology called ELIVATE that expands the range of usable payloads for antibody-drug conjugates, aiming to enable next-generation ADCs for oncology, inflammation, and autoimmune diseases.
BiotechDeep TechHealthtech
Myriam Ouberai(Founder)inBo Rode Hansen(Executive Director)in
Co-investorsCambridge Angels groupStart CodonACF InvestorsR42 Group
Stemnovate provides an integrated platform combining multiomics data, cell reprogramming technology, and mechanistic functional studies to accelerate drug discovery and clinical translation for rare diseases, neurodegenerative conditions, and other therapeutic areas across human and animal health.
AI & Machine LearningBiotechDeep Tech
Co-investorsCambridge Angels group
Exits · 2
1 IPOs · 1 acquisitions · showing 1Helus PharmaNASDAQ: HELP
Frequently asked questions
- How many investments has O2h Ventures made?
- O2h Ventures has 16 tracked investments, 2 of which have exited, including 2 dated in the last 24 months.
- What stage does O2h Ventures invest at?
- O2h Ventures invests at the Pre-Seed, Seed, Series A stages.
- What sectors does O2h Ventures focus on?
- O2h Ventures focuses on AI & Machine Learning, Biotech, Digital Health, Healthtech, IoT, Longevity.
- Where is O2h Ventures located?
- O2h Ventures is headquartered in Cambridge, GB.
- Who does O2h Ventures co-invest with?
- O2h Ventures most often shares deals with Force Over Mass Capital, JLS, Noetic, among 16 tracked co-investors.
Media · Podcasts & interviews
featuring the teamo2h Therapeutics EIS Fund – Sunil Shah, o2h Ventures
Wealth Club · Sunil Shah
Kuano: Biology through a Quantum lens
o2h group
Atelerix - Revolutionizing Biological Sample Preservation with Alginate Hydrogel Technology
o2h group
Oppilotech - Pioneering Drug Discovery with High-Resolution Computational Biology
o2h group
PharmEnable Tx | Re-imagining small molecule therapeutics through AI
o2h group
Enedra Tx - Personalized Medicine for Complex Cancers
o2h group
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