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O2h Ventures

Venture capital

Cambridge · Pre-Seed–Series A · 23 people tracked

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Investment thesis

o2h Ventures focuses on early-stage UK biotech and therapeutics companies, targeting disease areas such as cancer and neuroscience where small innovative biotechs supply new ideas to large pharma. The fund leverages AI to make sense of vast biological datasets and improve predictions on research resource allocation. It draws on grassroots relationships in the biotech community and its proprietary 2.7-acre Mill SciTech Park to incubate life science companies. Structured as an S/EIS-compliant vehicle, it offers UK taxpayers income, inheritance, and capital gains tax reliefs, aiming to widen the investor community supporting early-stage research in the UK.

Source: firm website, verified Sep 27, 2026.

Stage
Pre-Seed–Series A
HQ
Cambridge, GB
Instruments
Equity
Founded
2013
Last 12 months
1 investment
Tracked investments
16
IPOs
1
Acquisitions
1

Team · 23 people

from the firm's website

What they invest in

from 16 of 16 portfolio companies

Biotech ×14Deep Tech ×6Medical Devices ×6AI & Machine Learning ×5Healthtech ×5Digital Health ×2Mental Health ×2Enterprise Software ×1

HQs:United Kingdom×8Canada×1India×1Singapore×1

Investments · 16 tracked

founders shown can be your intro path

By year:2026 · 12025 · 12024 · 22023 · 32022 · 12021 · 12018 · 110 dated

Helus Pharmahelus.comin𝕏NASDAQ: HELP

Helus Pharma is a clinical-stage biopharmaceutical company developing small-molecule therapies for psychiatric and CNS conditions such as depression, anxiety, schizophrenia, and bipolar disorder.

BiotechDigital HealthHealthtechMental HealthToronto, CA

Eric So(Co-Founder, Executive Chairman)inJohn Kanakis(Co-Founder)inPaul Glavine(Co-Founder and Chief Growth Officer)inGabriel Fahel(Executive Officer)Douglas Drysdale(Executive Officer)Jacqueline Poriadjian(Executive Officer)

Co-investorsInnovating CapitalJLSNoetic

Exonate - companyexonate.comin𝕏✓ verified

Exonate is a biotechnology company developing treatments for retinal vascular diseases, with a lead asset (EXN407) intended as a topical therapy for diabetic retinopathy and diabetic macular oedema.

BiotechDigital HealthHealthtechMedical Devices

Olav Hellebø(Chief Executive Officer)in

Co-investorsWellcome TrustWren CapitalCambridge Angels groupEMV CapitalMartlet CapitalStoic VC+1 more

Metrion Biosciencesmetrionbiosciences.comin✓ verified

Metrion Biosciences provides ion channel screening and drug discovery services for pharmaceutical and biotech companies.

BiotechDeep TechMedical DevicesCambridge, GB

Marc Rogers(Founding Director)inJohn Ford(Founding Director)inKeith McCullagh(Founding Director)inLee Patterson(Chief Executive Officer)in

Co-investorsGresham House VenturesMaven Capital Partners

Stratosvirstratosvir.cominApr 2024✓ verified

Stratosvir develops engineered viral immunotherapy treatments for advanced cancers, including prostate cancer, using modified viruses to activate the body's immune system against tumors.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesStevenage, GB

Dr Chris Ullman(CEO)inAntonio Postigo(CSO)in

BoardPriya Mande(Chairman)in

Co-investorsDeep Science Ventures

Atelerix Seedatelerix.co.ukin𝕏

Atelerix develops hypothermic hydrogel encapsulation technology that stabilises and preserves fresh cells, tissues, and blood at room temperature, eliminating the need for cryopreservation and cold-chain logistics.

BiotechMedical DevicesNew Materials

Steve Swioklo(Founder)in

Co-investorsCambridge Angels groupFuture Planet CapitalOxford Technology ManagementUK Innovation & Science Seed Fund

Enedra Therapeuticsenedratx.cominMay 2025

Enedra analyzes tumor evolution patterns by decoding convergent genomic signatures from cancer genomic data.

AI & Machine LearningBiotechMedical Devices

Co-investorsDeep Science VenturesKU Leuven Research & Development

Financial Ombudsmanfinancial-ombudsman.org.ukin𝕏

The Financial Ombudsman Service is a free, statutory body set up by UK Parliament in 2001 to investigate and resolve complaints between consumers and financial businesses such as banks, insurers, and pension and investment providers.

FintechGovTechLegalTech

Co-investorsDeepbridge CapitalForce Over Mass CapitalFuel VenturesOxfordQVenturesSeneca Partners+1 more

Five Alarm Biofivealarmbio.comFeb 2023

Five Alarm Bio develops pharmaceutical compounds targeting a novel aging mechanism to prevent and treat age-related chronic diseases.

BiotechLongevity

William Bains(Founding scientist)in

Co-investorsCambridge Angels groupSyndicateRoom

Hawkhill Therapeuticshawkhilltherapeutics.comApr 2026

BiotechDundee, Scotland

Timothy Jason Sparey(Executive Officer)Antoine Boulanger(Executive Officer)Francisca Peixoto(Executive Officer)Christopher Andrew Woodland(Executive Officer, Director)

BoardMary Canning(Executive Officer)

Co-investorsEpidarex Capital

O2Ho2h.com

o2h group is a life science and technology investment and innovation organization that co-invests, co-creates and co-executes new ideas, offering venture funds, co-working labs, and community programs.

BiotechDeep TechImpact & Social GoodAhmedabad, IN

Penciltrypencil.comin𝕏Sep 2023Acquired

Pencil is an AI operating system for marketing that aggregates multiple AI models (from OpenAI, Google, Adobe, Runway, and Bria) into one orchestration layer with enterprise governance controls.

AI & Machine LearningEnterprise SoftwareMarketing TechSingapore, SG

Will Hanschell(CEO)inSumukh Avadhani(CTO)in

Co-investorsBrandtech VenturesEntrepreneur FirstWavemaker PartnersArtesianCatapult VenturesMartlet Capital+6 more

PharmEnablepharmenable.cominMay 2023 · $7.5M

PharmEnable applies AI to small molecule drug discovery, focusing on challenging and data-sparse biological targets that traditional methods struggle to address.

AI & Machine LearningBiotechDeep Tech

Hannah Sore(Founder)in

Co-investorsCambridge Angels groupMartlet CapitalMC Healthcare VenturesDiamond Edge VenturesParkwalk AdvisorsWren Capital

PhoreMostphoremost.comin𝕏Sep 2024

PhoreMost is a biotechnology company developing small molecule drugs and targeted protein degradation therapeutics for cancers with high unmet clinical need, with a lead program (PMC-001) for primary and metastatic brain cancers in Phase 1/2a clinical evaluation.

BiotechMedical DevicesCambridge, GB

Co-investorsAmadeus Capital PartnersAstellas Venture Management LLCCambridge Angels groupUniversity of Cambridge EnterpriseAmadeus Capital SAParkwalk Advisors

Small Pharmasmallpharma.comJan 2021

Helus Pharma is a clinical-stage pharmaceutical company developing novel serotonergic agonists—synthetic molecules that activate serotonin pathways—as next-generation mental health therapies.

BiotechHealthtechMental HealthLondon

Eric So(Co-Founder, Executive Chairman)Carol Routledge(Executive Officer)George Tziras(Director)Khalid Howladar(Director)Marie Claire Layzell(Executive Officer, Director)Peter Rands(Executive Officer, Director)

Spireaspirea.co.ukinJun 2022 · $3M

Spirea develops a multivalent ADC linker technology called ELIVATE that expands the range of usable payloads for antibody-drug conjugates, aiming to enable next-generation ADCs for oncology, inflammation, and autoimmune diseases.

BiotechDeep TechHealthtech

Myriam Ouberai(Founder)inBo Rode Hansen(Executive Director)in

Co-investorsCambridge Angels groupStart CodonACF InvestorsR42 Group

Stemnovatestemnovate.co.ukin𝕏May 2018

Stemnovate provides an integrated platform combining multiomics data, cell reprogramming technology, and mechanistic functional studies to accelerate drug discovery and clinical translation for rare diseases, neurodegenerative conditions, and other therapeutic areas across human and animal health.

AI & Machine LearningBiotechDeep Tech

Co-investorsCambridge Angels group

Exits · 2

1 IPOs · 1 acquisitions · showing 1

Helus PharmaNASDAQ: HELP

Frequently asked questions

How many investments has O2h Ventures made?
O2h Ventures has 16 tracked investments, 2 of which have exited, including 2 dated in the last 24 months.
What stage does O2h Ventures invest at?
O2h Ventures invests at the Pre-Seed, Seed, Series A stages.
What sectors does O2h Ventures focus on?
O2h Ventures focuses on AI & Machine Learning, Biotech, Digital Health, Healthtech, IoT, Longevity.
Where is O2h Ventures located?
O2h Ventures is headquartered in Cambridge, GB.
Who does O2h Ventures co-invest with?
O2h Ventures most often shares deals with Force Over Mass Capital, JLS, Noetic, among 16 tracked co-investors.

Media · Podcasts & interviews

featuring the team

o2h Therapeutics EIS Fund – Sunil Shah, o2h Ventures

Wealth Club · Sunil Shah

Kuano: Biology through a Quantum lens

o2h group

Atelerix - Revolutionizing Biological Sample Preservation with Alginate Hydrogel Technology

o2h group

Oppilotech - Pioneering Drug Discovery with High-Resolution Computational Biology

o2h group

PharmEnable Tx | Re-imagining small molecule therapeutics through AI

o2h group

Enedra Tx - Personalized Medicine for Complex Cancers

o2h group

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