Protocol Labs — Full Portfolio

Amera Health Solutions provides a data integration platform that connects fragmented claims processing systems for health plans.

Data & InfrastructureEnterprise SoftwareFintechHealthtechInsurTechNew York City, US

DKDeep Kapur(CEO)inLTLouise Tanski(Founder)in

Co-investorsVAValia VenturesY Y CombinatorALAlumni VenturesBABase10 PartnersC C Square CapitalCOComma Capital+7 more

Anjuna provides software that runs applications and data inside hardware-encrypted secure enclaves across major chip, cloud, and system vendors, protecting them from malware, insiders, and other threats.

AI & Machine LearningCloud ComputingCybersecurityDeep TechEnterprise SoftwareSan Francisco, US

AYAyal Yogev(CEO)inSteve WeisYMYan Michalevsky(CTO)in

BoardPBPeter Barrett(Director)inLJLonne Jaffe(Director)in

Co-investorsINInsight PartnersM M VenturesSISINEWAVE VENTURESALAlpha Intelligence CapitalDCDCVC (Data Collective)DODorm Room+12 more

Anytype is a decentralized collaboration and note-taking platform that emphasizes data privacy through local encryption and peer-to-peer synchronization.

Crypto & Web3Developer ToolsFuture of WorkSector AgnosticMoscow, US

Co-investorsALAltaIR CapitalBABalderton CapitalINInflection.xyzS1s16SCScript CapitalSQSquareOne+4 more

Anytype is a privacy-focused collaboration and workspace platform that allows users to organize information, communicate, and create content with local-first encryption and offline functionality.

Future of WorkSaaS

JSJanna Sharipova(Founder)inAnton Pronkin(Founder)in

Co-investorsSCScript CapitalBABalderton CapitalFAFabric VenturesJUJutta SteinerNENew Forge

Argument builds systems for verifiable computing by combining zero-knowledge cryptography, formal verification, and distributed consensus technologies.

Crypto & Web3Deep TechDeveloper ToolsEnterprise SoftwareBoston, US

JBJohn Burnham(Founder)inGBGabriel Barreto(Founder)inSBSamuel Burnham(Founder)in

Co-investorsBIBig Brain HoldingsSASamsung NextVAVarys CapitalY Y CombinatorDWDWeb3 CapitalIOIOSG Ventures+6 more

Bifrost develops smart contracts that enable automated asset transfer upon death, allowing heirs to claim cryptocurrency holdings from self-custody wallets.

Crypto & Web3FintechSan Francisco, US

KSKartik Sathappan(Founder)inSBSamraaj Bath(Founder)inBWBen Wong(Founder)inRebekkah Kandiah(Founder)

Co-investorsY Y CombinatorCACaruso VenturesCHChampion Hill VenturesDVDVCFOFoundersOROrange DAO+3 more

BitRobot is a decentralized network that coordinates researchers, hardware operators, and compute providers to advance embodied AI and robotics R&D.

AI & Machine LearningCrypto & Web3Robotics

Michael Cho

Co-investorsBIBig Brain HoldingsTATangent VenturesTITioga Capital PartnersFAFabric VenturesVIVirtuals ProtocolZEZee Prime Capital

Blockcast builds decentralized, community-owned content delivery network (CDN) infrastructure that uses single localized streams to reduce internet congestion and delivery costs.

Crypto & Web3Data & InfrastructureMedia & Entertainment

Omar(Founder)

Co-investorsALAlliance DAO (ex DeFi Alliance)LALattice CapitalANAnatoly YakovenkoFIFinality Capital PartnersRWRW3 VenturesZEZee Prime Capital

Bunkyr provides an API that lets applications implement zero-knowledge encryption and password recovery without requiring users to manage seed phrases or backup codes.

Crypto & Web3CybersecurityDeveloper ToolsEnterprise SoftwareSaaSDenver, US

Reid BartonMichael BrzozowskiMike Lewis

Co-investorsSOSoma CapitalY Y CombinatorAGAgrolimen VenturesEXExceptional CapitalFAFAST — by GETTYLABGOGoat Capital+1 more

Canza Finance is a Web3 company combining DeFi, crypto-assets, and traditional financial infrastructure to provide financial products for individuals and businesses in Africa and other emerging markets.

Crypto & Web3Fintech

PNPascal Ntsama IV(Co-founder & CEO)inOOOyedeji Oluwoye(Co-founder & CMO)in

Co-investorsADAdaverseCOConsenSys MeshFEFenbushi CapitalFLFlori VenturesHYHyperithmMAMapleblock Capital+5 more

Codec develops video creation software that transforms everyday videos into polished movies for smartphone users.

AI & Machine LearningConsumerCreator EconomyMedia & EntertainmentSan Francisco, US

MDMerwane Drai(Founder)inRosco Kalis

Co-investorsY Y CombinatorANAngel InvestCACaffeinated CapitalSCSciFi VC

CoinFeeds offers custom AI agent development for investment funds, enabling managers to connect natural language processing to financial data sources including SEC filings, earnings calls, and internal documents.

AI & Machine LearningCrypto & Web3Fintech

Co-investorsCOCoinbase VenturesHUHuobi CapitalTHThird Kind Venture CapitalY Y Combinator

Concept Art House is an art outsourcing studio for game developers, producing character designs, 2D and 3D assets, animation, and VFX for AAA, mobile, and trading card games.

Creator EconomyCrypto & Web3GamingMedia & EntertainmentSan Francisco, US

James(Founder / CEO)JCJenny Chen(President & Founder)

BoardMatthew Le Merle(Chairman)

Co-investorsANAnimoca BrandsDADapper LabsAPAppWorks VenturesPOPolymorphic CapitalRERed Beard VenturesAPAppWorks+11 more

A service that automatically generates and launches multiple customized landing pages for businesses, tailored to different campaigns and use cases to improve conversion rates and search visibility.

AI & Machine LearningDeveloper ToolsEnterprise SoftwareSan Francisco, US

SBSamraaj Bath(Founder/CEO)inSamuel Barnholdt

Co-investorsLOLobster CapitalY Y CombinatorANAndreessen HorowitzCACapitalize VCFOFoundersPEPeak+2 more

Element Materials Technology provides materials testing, product qualification, and assurance services for customers in aerospace, space, defense, and energy sectors.

Advanced ManufacturingDeep TechDefense TechEnterprise SoftwareMedical DevicesNew Materials

Rick Sluiters(CEO of Element Aero, Space & Defense)

Co-investors3I3i GroupFOForesite CapitalMEMetaplanetT.T. Rowe PriceVEVenrock

Element is an NFT marketplace on Ethereum where users can create, swap, and trade NFT collections, with real-time floor price and volume data tracking.

Crypto & Web3Marketplaces

Co-investorsBIBitDAOMAMantle NetworkFOForesite CapitalMEMetaplanetT.T. Rowe PriceVEVenrock

Element modernizes legacy mainframe systems using its Global Context Engine, which performs deterministic analysis of a codebase to extract system infrastructure, data flows, and business logic as a foundation for modular transformation.

AI & Machine LearningDeveloper ToolsEnterprise SoftwareParis, FR

AWAlexander Wiener(CEO)inLMLukas Marienfeld(CTO)in

Co-investorsENEntrepreneur FirstPRProject EuropeTRTranspose Platform ManagementAUAutomatticDCDCVC (Data Collective)FOForesite Capital+6 more

Enlightra develops photonic optical interconnects using comb laser technology to enable high-bandwidth, low-power data transfer for data centers and AI infrastructure.

Advanced ManufacturingData & InfrastructureDeep TechHardwareLausanne, CH

JJJohn Jost(Founder)inMKMaxim Karpov(Founder)in

Co-investorsALAloniqBLBlank Space VenturesEIEight CapitalPIPioneerSOSoma CapitalTRTRAC (Third Round Analytics Capital)+6 more

A marketplace that allows creators to sell face filter designs as NFTs to fans and provides tools for designing augmented reality filters for social media platforms.

ConsumerCrypto & Web3San Francisco, US

CHChris Horne(Founder)in

Co-investorsY Y CombinatorDIDivergenceJOJosh HannahPIPioneerPOPortkey Technologies PteSOSoma Capital

Finnt builds AI agents that execute accounting and controllership tasks for finance teams, generating journal entries and financial statements with audit documentation in minutes.

AI & Machine LearningEnterprise SoftwareFintech

AIAnji Ismail(CEO)inFEFaouzi EL YAGOUBI(Founder)inPaula E. Vasco V.(Operations Manager)

Co-investorsDIDiaspora VenturesISIsaiISISAI GestionY Y Combinator30305 VenturesFRFranklin Templeton+10 more

Fluence is a decentralized "cloudless" computing platform that combines blockchain with high-performance computing to let developers build and scale applications without relying on centralized cloud providers.

AI & Machine LearningCloud ComputingCrypto & Web3Deep Tech

EPEvgeny Ponomarev(Co-Founder & COO, Cloudless Labs)inTom Trowbridge(Co-Founder & CEO, Cloudless Labs)DKDmitry Kurinskiy(Co-Founder & CTO, Cloudless Labs)inBernhard Borges(Chief Scientist, Cloudless Labs)

Co-investorsMUMulticoin CapitalPOPolymorphic CapitalSISignum Capital1K1kxDIDistributed GlobalTITiger Global Management

Functionland operates a decentralized blockchain network (Fula) managed by Fula Governance Association, a Switzerland-based entity.

Cloud ComputingCrypto & Web3Data & InfrastructureFintechIoTToronto, CA

Co-investorsDEDelta BlockchainTETechstarsCOContango Digital AssetsDODoraHacksMAMaster VenturesOUOutlier Ventures+1 more

Gensyn provides decentralized infrastructure for AI models to train, verify, trade, and evolve using cryptographic verification and on-chain identity mechanisms.

AI & Machine LearningCrypto & Web3Data & InfrastructureLondon, GB

BFBen Fielding(Founder)inHGHarry Grieve(Founder)in

Co-investorsA1a16z cryptoANAndreessen HorowitzCOCoinFundCOCounterview CapitalDIDigital Finance GroupENEntrepreneur First+13 more

GLIF provides DeFi and liquid staking infrastructure for the Filecoin network, including staking pools and a loyalty rewards program tied to its $GLF token.

Crypto & Web3Data & InfrastructureFintech

Jonathan Schwartz(Founder)

Co-investorsMUMulticoin CapitalZEZee Prime CapitalSTStruck CapitalBIBig Brain HoldingsFIFinTech Collective

Golden builds a self-constructing knowledge graph that combines artificial and human intelligence to automatically map and reconcile human knowledge from millions of disparate sources.

AI & Machine LearningData & InfrastructureEnterprise SoftwareSan Francisco, US

JGJude Gomila(Founder)inFrancois Ajenstat(Founder)

Co-investorsFOFounders FundGIGigafundSVSV AngelA1a16z cryptoANAndreessen HorowitzDCDCVC (Data Collective)+16 more

Hex Trust builds technology platforms serving large financial institutions in the banking and finance sector.

Crypto & Web3Enterprise SoftwareFintech

AQAlessio Quaglini(Founder & CEO)in

Co-investorsBABaboon VCETEterna CapitalFEFenbushi CapitalQBQBN CapitalRYRyze LabsTETessera Venture Partners+7 more

Impossible Cloud provides enterprise cloud infrastructure with a channel/partner-first model, offering S3-compatible object storage and bare metal NVIDIA GPU servers with transparent per-terabyte and per-GPU-card-hour pricing.

AI & Machine LearningCloud ComputingData & InfrastructureEnterprise SoftwareHamburg, DE

DKDr. Kai Wawrzinek(Co-founder)inCKChristian Kaul(Founder)in

Co-investorsG+G+D VenturesLBLBBW Venture Capital GmbHNGNGP Capital1K1kxHVHV CapitalTSTS Ventures+1 more

Infura provides infrastructure and API services for developers building decentralized applications.

Crypto & Web3Data & InfrastructureDeveloper Tools

EGEleazar Galano(Founder)

Co-investorsBIBitDAODEDeepTech VenturesFEFenbushi CapitalIOIOSG VenturesMAMantle NetworkALAlameda Research+4 more

Joyn is a software product that connects engineering and work tools to give customer-facing teams visibility into product progress.

AI & Machine LearningHR TechBrooklyn, US

SMSeraina Macia(Founder & CEO)

Co-investorsPRProject Voice Capital PartnersTETechstarsAVAvanta VenturesAXAxia8 VenturesBIBixin VenturesCOCohen Circle+8 more

Laudspeaker provides an open source platform for mobile marketing automation and customer onboarding, letting teams create segmented push notification, SMS, and email campaigns with complex scheduling rules.

Enterprise SoftwareMarketing TechSaaSSan Francisco, US

ABAbheek Basu(Founder)inMCMahamad Charawi(Founder)in

Co-investorsY Y Combinator

Magna is an all-in-one platform for crypto companies to launch, manage, and scale tokens, offering token operations, treasury management, stablecoin management, and distribution across a global web3 ecosystem.

Crypto & Web3Developer ToolsEnterprise SoftwareFintechSaaSNew York City, US

BFBruno Faviero(Founder)inAKArun Kirubarajan(Founder)inJoey Poh(Chief of Staff)JCJack Chapman(Software Engineer)inRosh Singh(Head of Engineering)Julie Imbriale(Head of Operations)

Co-investorsALAlumni VenturesASAsymmetricBEBehind Genius VenturesBIBig Brain HoldingsDODorm RoomJUJude Gomila+16 more

Singapore-based maker of a browser extension whose AI-driven, blockchain-backed virtual pets live on the user's screen.

Crypto & Web3FintechGamingSingapore, SG

Co-investorsBLBlueYard CapitalTETechstarsACAcequia Capital (AceCap)

POAP Inc builds digital collectibles on Web3 that serve as proofs of attendance at events and experiences, enabling people to preserve memories and discover communities.

Crypto & Web3SocialNew York, US

PWPATRICIO WORTHALTER(Executive Officer, Director)inOLGA ISABEL GONZALEZ(Executive Officer)

BoardRMRICO MALLOZZI(Director)inTOMAS SORACCO(Director)

Co-investors35359 CapitalA.A.Capital VenturesADAdvancit CapitalARArchetypeCOCollab+CurrencyINInspired Capital+11 more

Quicknode provides blockchain infrastructure services that enable developers and enterprises to build and deploy decentralized applications across multiple blockchains.

Crypto & Web3Data & InfrastructureDeveloper ToolsEnterprise SoftwareSaaSMiami, US

DSDmitry Shklovsky(Founder)inMKManuel Kreutz(Founder)inANAlexander Nabutovsky(Founder)inAlex Nabutovsky(Founder)ABAuston Bunsen(Founder)inANAlexander Nabutovskyin

Co-investorsY Y Combinator1010T FundANAngel Collective Opportunity FundARArrington CapitalGAGaingelsLGLG Technology Ventures+14 more

Radix Labs builds operating-system software for biology laboratories to run and automate their lab workflows.

BiotechDeep TechHealthtechIoTMedical DevicesBoston, US

DSDhasharath Shrivathsa(Founder)inIPIan Paul(Founder)in

Co-investorsY Y CombinatorBLBlindspot Ventures Management CoFIfirstminute capitalLILiquid VenturesSOSound VenturesTHThe Engine Ventures

Spexi provides drone-captured geospatial imagery delivered via API for machine learning pipelines.

AI & Machine LearningData & InfrastructureDeep TechHardware

BLBill Lakeland(Founder)in

Co-investorsALAlliance DAO (ex DeFi Alliance)MOMoonshots CapitalBLBlockchange VenturesCACambrian Asset ManagementDADapper Labs

Spheron operates a GPU cloud marketplace that aggregates compute capacity from certified data centers worldwide, offering NVIDIA GPUs (H100, H200, B200, A100) at 40-60% below hyperscaler pricing.

AI & Machine LearningCloud ComputingData & Infrastructure

PMPrashant Maurya(Founder)in

Co-investorsARArcanum VenturesCOConsenSys MeshISiSeedNENexus Venture PartnersZ4Z47

Spice AI provides a unified data and AI engine that enables developers to build AI-driven applications without requiring specialized expertise in data science or machine learning.

AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSeattle, US

LKLuke Kim(Founder)inLHLane Harris(Co-Founder & VP of Engineering)inPLPhillip LeBlanc(Founder)in

Co-investorsALAlumni VenturesASAsymmetricBABasis Set VenturesBLBlackbird VenturesCACardinia VenturesGEGeek Ventures+8 more

SpruceID provides digital identity systems for governments and regulated industries, enabling secure verification and authentication across legacy and modern infrastructure.

Crypto & Web3CybersecurityData & InfrastructureDigital HealthEnterprise SoftwareGovTechNew York City, US

WCWayne Chang(Founder)inGRGregory Rocco(Founder)inECEric Chen(Head of Engineering)inDani Johnson(Head of Operations)Claud Vicencio(Executive Assistant)Elissa Maercklein(Head of Marketing)

Co-investors51515 Ventures6 6 Degrees CapitalA.A.Capital VenturesA1a16z cryptoANAndreessen HorowitzBIBitkraft Esports Ventures+24 more

Spruce Systems provides an AI tool for commercial landscaping companies that captures property context during routine maintenance and generates site audit reports for account managers.

AI & Machine LearningSaaSSales Tech

MMMax Makeev(Founder)inMFMatt Fitzgerald(Founder)in

Co-investors202048 VenturesANAndreessen HorowitzELElectric CapitalETEthereal Ventures Management Ltd.OKOkta VenturesRORobot Ventures+2 more

Synchron develops brain-computer interface technology delivered via catheter to restore or improve motor and cognitive function in people with impairment or decline.

BiotechDeep TechMedical DevicesCampbell, US

TJThomas James Oxley(Executive Officer, Director)NONicholas Opie(Founder)inTOThomas Oxley(Founder)inTom Oxley(Founder)

BoardRahul Sharma(Director)AMAlex Morgan(Director)in

Co-investorsALAlumni VenturesARARCH Venture PartnersFOForepont Capital PartnersIDID8 InvestmentsINIn-Q-TelK2K2 Global+15 more

Talent Protocol computes a "Builder Score" that turns a person's public GitHub and blockchain activity into a verified onchain reputation score, run in the browser using public APIs with no account required.

AI & Machine LearningCrypto & Web3Developer Tools

Co-investorsCOCoinbase VenturesFLFlori VenturesFOFounderheads,GOGood News Ventures

thirdweb provides a developer platform for building web3 applications, offering tools for creating and managing tokens, bridging and swapping across blockchain networks, and wallet infrastructure.

Crypto & Web3Developer Tools

Co-investorsBIBitDAODRDraft Ventures LlcFEFelicis VenturesFOFoundersHAHaun VenturesMAMantle Network+7 more

TransCrypts is a blockchain-based platform for verifying and sharing employment, health and educational credentials.

CybersecurityData & InfrastructureFintechNewark, US

ZZZain Zaidi(Founder)inZain Z(Founder)Ali Zaheer(Founder)

Co-investorsALAlpha EdisonALAlumni VenturesATAtland VenturesBEBeyond CapitalCACAL InnovationCACalifornia Innovation Fund+14 more

Unfaze AI creates product images and short-form promotional videos using AI tools for marketing and ecommerce content.

AI & Machine LearningE-commerceEnterprise SoftwareMarketing TechSan Francisco, US

SSSoumil Singh(Co-Founder & CEO)inDGDhruv Gupta(Co-Founder)in

Co-investorsCICitta CapitalY Y CombinatorAMAmino CapitalENEniac VenturesHAHack VCMEMetapurse+4 more

WeatherXM operates a community-powered decentralized (DePIN) weather network where owners deploy solar-powered weather stations and earn $WXM token rewards for contributing data.

Climate TechCrypto & Web3IoT

STStratos Theodorou(Founder)inManolis Nikiforakis(Founder)Nikos Tsiligaridis(Founder)

Co-investorsPLPlaceholder VCALAlumni VenturesBOBorderless VentureCOConsenSys MeshDLdlabFAFaction+6 more

Zama provides encryption technology for onchain finance that keeps blockchain addresses public while encrypting transaction amounts and commercial references at the token level.

AI & Machine LearningCrypto & Web3CybersecurityDeep TechFintechSilicon Valley, FR

RHRand Hindi(Founder)inPascal Paillier(Founder)

Co-investorsCOCoinListETEterna CapitalHAHack VCLULunar VenturesMEMetaplanetMUMulticoin Capital+7 more