National Institutes of Health (NIH) — Full Portfolio

Sinopia Bio is a biotechnology company developing a therapeutic pipeline focused on Parkinson's disease.

BiotechSan Diego, US

ABAarash Bordbar(Executive Officer, Director)inBernhard Palsson(Director)Iman Famili(Director)

BoardArthur T Suckow(Director)

SINTX develops advanced ceramic technology solutions for biomedical, aerospace, defense, and energy industries.

BiotechDeep TechDefense TechEnergyMedical DevicesNew Materials

Nikole Kimes(Founder)Samir Kaul(Founder)Susan Lynch(Founder)

Co-investorsGLGlobal BrainSESeventure Partners

Sirius Thinking creates animated and puppet characters along with educational content for media platforms, drawing on talent from major children's entertainment companies.

Creator EconomyEdTechMedia & EntertainmentNew York City, US

John SculleyChristopher CerfNorman StilesMichael Frith

Sirnaomics is an RNA therapeutics company developing RNA interference (RNAi) drugs using its proprietary PNP (Peptide Nanoparticle) delivery platform for extra-hepatic delivery and its GalAHead technology for controlling therapeutic duration.

BiotechHealthtechGaithersburg, US

Yang (Patrick) Lu, PhD(Executive Officer, Director)George Ji(Executive Officer)inMichael Molyneaux(Executive Officer, Director)

BoardXiaochang Dai(Director)Ping Lau(Director)Mike Ghias(Director)

Co-investorsGRGRA Venture

SiVEC Biotechnologies develops BactPac, a live biotherapeutic delivery platform that enables targeted delivery of nucleic acid therapies and gene editing therapies for clinical advancement.

BiotechDeep TechMedical DevicesFort Collins, US

Lyndsey Linke, PhD(CEO, Co-founder, and Chairman of the Board of Directors)Darcy Mora(VP of Operations, Co-founder)inLyndsey Linke(Executive Officer, Director)Sibylle Hauser(Director)

BoardRichard A. Freed III(Director)David Sherris(Director)

Co-investorsCOColorado BioScience Association

Co-investorsPLPlug and Play Ventures

SkinAxis is a biotechnology company that produces genetically engineered 2D and 3D human skin cell models, including keratinocytes, melanocytes, fibroblasts, and reconstituted skin and oral mucosa equivalents, for testing active ingredients and drugs.

BiotechDeep TechHealthtech

Sky Park Labs develops visual intelligence and AI systems for industrial, government, and social-impact applications.

AI & Machine LearningDeep TechGovTech

Skyran Biologics develops eyedrop therapeutics to treat blinding ocular diseases such as diabetic retinopathy and age-related macular degeneration.

BiotechDigital HealthHealthtechMedical DevicesState College, US

Dr. Joyce Tombran-Tink(Founder and Chief Scientific Officer)Dr. Colin Barnstable(Founder)

Smart Information Flow Technologies (SIFT) is a research and development consulting company working in natural language processing, automated planning, cybersecurity, supervisory control, healthcare, and human-automation interaction.

AI & Machine LearningCybersecurityDeep TechMinneapolis, US

Smarty Ears develops research-based digital solutions for speech therapy, language development, and literacy instruction, serving speech-language pathologists, educators, and families in special education.

AI & Machine LearningDigital HealthEdTechHealthtechSaaS

Barbara Fernandes(Founder)

Smyl (Supporting Mobility and Longevity) is a home-based fall prevention and fitness program for adults aged 50 and older, offering personalized coaching, health assessments, and short at-home activities to improve strength, balance, and mobility.

Digital HealthLongevityWellness & Fitness

SNJ Pharma is developing SNJ101, a plasmin-independent thrombolytic agent for the treatment of thrombotic disorders.

BiotechHealthtech

Sofie is a radiopharmaceutical company involved in contract manufacturing and the development of F18-labeled PET (Positron Emission Tomography) radiopharmaceuticals and active pharmaceutical ingredients (FAPI) for patient imaging and treatment.

BiotechHealthtechMedical DevicesCulver City, US

Michael Phelps(Director)SBStan Berman(Executive Officer)inPPPatrick Phelps(Executive Officer, Director)inJohannes Czernin(Director)James Heath(Director)

BoardAjit Singh(Director)

Co-investorsCYCycad Group LLC

Fort Collins, US

Robert Calvin Goforth(Director)Michael Artinger(Executive Officer, Director)

Solenic Medical is a medical company; this page is an investor contact form and does not describe the company's products or technology in detail.

Medical DevicesCollege Station, US

JYJames Y Lancaster(Executive Officer, Director)in

BoardJohn Hodock(Director)Robert Calvin Goforth(Director)

Co-investorsSHShangBay Capital LLCSUSugati VenturesJOJohnson & Johnson Innovation – JJDC

Co-investorsTATargeted Technology Funds

QuartzBio provides a conversational AI platform that enables clinical-stage biopharma teams to gain real-time insights from fragmented sample, clinical, and biomarker data across their entire lifecycle.

AI & Machine LearningBiotechData & InfrastructureDigital HealthHealthtech

Co-investorsNANat Turner

SonALAsense develops Sonodynamic Therapy (SDT), a non-invasive drug-device cancer treatment combining its SONALA-001 drug with an ultrasound device to treat deadly cancers such as High-Grade Gliomas and DIPG.

BiotechHealthtechMedical DevicesBerkeley, US

Stuart Marcus(Founder and CSO)inMark P. de Souza(President and CEO)in

Co-investorsKEKeiretsu Forum

Baltimore, US

Ellington West(Executive Officer, Director, Promoter)inIan McLane(Executive Officer, Director)Jaishree McLane(Executive Officer, Director, Promoter)Brandon Dottin-Haley(Executive Officer, Director, Promoter)

BoardIlene Busch-Vishniac(Executive Officer, Director, Promoter)Leslie Wise(Director)

Co-investorsCACatalytic Impact FoundationGAGaingelsSASand Hill Angels

SonoMotion develops ultrasound-based medical devices for treating kidney stones, working with urologists and clinical partners.

Deep TechHealthtechMedical DevicesSan Mateo, US

OLOren Levy(Chief Executive Officer, Co-Founder)inPaul Douglas Corl(Executive Officer)Doug Corl(Chief Technology Officer)Michael Bailey(Executive Officer, Director)Barbrina Dunmire(Director)

Co-investorsBIBioventures Investors

Soteria Biotherapeutics develops protein-based biotherapeutics and small molecules using its LITE Switch technology platform for drug discovery and development across oncology, immune-oncology, and inflammatory disease indications.

BiotechDeep TechHealthtechMedical DevicesWellness & FitnessSan Francisco, US

Jim Wells(Co-founder, Scientific Advisory Board Chair)KMKristine M Ball(Executive Officer, Director)inZHZachary Hill(Executive Officer, Director)in

BoardNisha Marathe(Director)DADavid Allison(Director)inKGKeno Gutierrez(Director)in

Co-investors5A5AM VenturesNONovartis Venture FundRORoche Venture FundVEVersant VenturesBIBioGeneration VenturesWEWestlake Village BioPartners

Soterix Medical manufactures PainX TENS devices for drug-free pain relief through transcutaneous electrical nerve stimulation.

BiotechDeep TechDigital HealthHealthtechMedical DevicesTri-state area, US

Sound Pharmaceuticals (SPI) is a Seattle-based biotech developing drug therapeutics, including its lead candidate SPI-1005, to prevent and treat sensorineural hearing loss, tinnitus, and Meniere's disease.

BiotechHealthtechSeattle, US

JKJonathan Kil(Executive Officer, Director)inJames Paul Rickey(Executive Officer)Eric Lynch(Executive Officer, Director)

BoardGlenn Kawasaki(Director)Joseph Ashley(Director)

South Rampart Pharma is a clinical-stage biopharmaceutical company developing non-opioid, non-NSAID small molecule drugs for pain treatment, with a focus on reducing toxicity and addiction risks associated with existing analgesics.

BiotechDigital HealthHealthtechMedical Devices

Sparian Biosciences is a biotech company developing novel therapeutics for pain and substance use disorders, with a focus on compounds derived from opiate receptor biology research.

BiotechDigital HealthHealthtechLongevityMedical DevicesNew York City, US

Jeff Reich(Co-founder, MD)Gavril Pasternak(Co-founder, MD, PhD)Dr. Amitabh Majumdar(Scientific Co-founder)Dr. Pan(Scientific Co-founder)

Spark Biomedical develops wearable neurostimulation devices for bioelectronic medicine applications, primarily targeting mental health, women's health, hemostasis, and pediatrics.

BiotechDigital HealthHardwareHealthtechMedical DevicesDallas, US

DPDaniel Powell(President & Chief Executive Officer)inACAlejandro Covalin(Chief Technology Officer)inNKNavid Khodaparast(Chief Science Officer)inTed Costopoulos(Director)Carl R. Deeley(Director)

Co-investorsAGAggie Angel NetworkPAPathway to CuresWAWave Ventures

SPARK Neuro develops brain health measurement technology for early detection and monitoring of cognitive conditions like dementia, targeting healthcare providers and individuals.

AI & Machine LearningDigital HealthHealthtechMedical DevicesNew York, US

SGSpencer Gerrol(Founder & CEO)inMGMarinela Gombosev(President & COO)inHLHarry Leider(Chief Strategy Officer)inRichard Caselli(Medical Director)Jeremy Sziklay(Executive Officer, Director)William Ryan McGarry(Director)

Co-investorsCOConnectivity VenturesDRDreamers VCGAGaingelsKIKing River CapitalR1R136 VenturesTHThe Venture Collective+3 more

Spatial Genomics develops the Gene Positioning System (GenePS), an automated instrument for spatial genomics experiments that maps gene expression within cells at subcellular resolution.

AI & Machine LearningBiotechDeep TechHardwareMedical Devices

Speak Agent develops AI-powered instructional technology designed to support academic language development across K-12 content areas.

AI & Machine LearningEdTech

Ben Grimley(CEO)Andrea E. Blair(Secondary Mathematics Lead)Brian Camus(Secondary Science Lead)

Co-investorsELElevate Ventures

Undivided is a subscription service that helps parents of children with disabilities navigate IEPs, 504 plans, school districts, and disability and insurance benefits, combining AI tools, a HIPAA-compliant digital document binder, plain-language guidance, and human "Navigators" who are experienced parents.

AI & Machine LearningDigital HealthEdTechLos Angeles, US

JLJason Lehmbeck(Co-Founder and Executive Chairman)inJohn Zimmerman(Co-Founder and CTO)SBSeth Besse(CEO)in

Co-investorsBABarrel Ventures

bioMérieux develops in vitro diagnostic solutions for clinical laboratories and healthcare teams, covering areas such as antimicrobial stewardship, sepsis detection, respiratory infections, and COVID-19.

BiotechHealthtechMedical DevicesMountain View, US

Paul Rhodes(Executive Officer, Director)Ray Martino(Director)PGPaul Grossman(Director)in

Co-investorsTETelegraph Hill Partners

Specifica is an antibody engineering company that develops proprietary antibody libraries using next-generation sequencing, enabling drug-like antibodies for pharmaceutical discovery.

AI & Machine LearningBiotechDeep TechSanta Fe, US

Andrew Bradbury(CSO, Founder)Sara D'Angelo(CTO)

Spectra Research provides advanced research, development, and manufacturing services for government and industry customers, specializing in electronic, electromagnetic, and laser technology products including antenna design, RFID, sensors, and electro-optical systems.

Deep TechDefense TechHardwareDayton, US

Spectradyne manufactures the ARC particle analyzer, an instrument for measuring nanoparticle size, concentration, and fluorescent properties simultaneously using microfluidic resistive pulse sensing technology.

BiotechDeep TechHardwareMedical Devices

Franklin Monzon(Co-founder)Jean-Luc Fraikin(CEO)

Spectragen Informatics provides data analysis services and products for biological mass spectrometry, serving companies, government agencies, and academic researchers.

AI & Machine LearningBiotechData & Infrastructure

Spectral Energies develops advanced laser and propulsion technologies for the aerospace, defense, transportation, and energy sectors, drawing on extensive research and government contracts with agencies including DoD, NASA, and DoE.

Deep TechDefense TechEnergyHardwareBeavercreek, US

Sukesh Roy(CEO)Sivaram P. Gogineni(President)Mitch Icard(COO)

AI medical diagnostics company whose DeepView imaging platform predicts whether burns and other wounds will heal.

BiotechDallas, US

J. Michael DiMaio(Executive Officer, Director)John H, Stevens(Director)Erich Spangenberg(Director)

Co-investorsCACalculus Capital Ltd.

SpecTree develops portable sampling devices that collect particles from surfaces and capture ultrafine bioaerosols with high efficiency for environmental monitoring, public health surveillance, and industrial safety applications.

CleantechDeep TechDefense TechHardwareHealthtechSeattle, US

HealthtechLafayette, US

Brian Kopp(Executive Officer, Promoter)inSMSteve Mogensen(Executive Officer, Director, Promoter)in

Co-investorsELElevate Ventures

SpellBound builds mobile augmented reality games and educational tools to engage and distract patients across stages of the care journey, including waiting rooms, clinical point of care, and at-home settings.

AI & Machine LearningDigital HealthHealthtech

CYChristina York(Founder & CEO)in

Co-investorsINInvest MichiganLILighthouse Network Ventures Llc

Speragen is a biotech company founded to address the challenges faced by patients with rare genetic disorders, specifically SSADH deficiency, by accelerating the development and availability of therapies.

Biotech

A mother of two children affected with SSADH deficiency

Spheryx develops Total Holographic Characterization technology for analyzing suspensions at the sub-visible particle level, including detecting protein aggregates and particles in biopharmaceuticals.

BiotechDeep TechHardwareNew York, US

LPLaura Philips(Executive Officer, Director)inDavid Grier(Director)

Spike Neuro develops advanced neural probes and surface array technologies for neuroscience research, enabling academic and commercial researchers to conduct high-quality electrophysiology studies for brain-computer interface and medical device development.

BiotechDeep TechHardwareHealthtechMedical DevicesAnn Arbor, US

Lawrence Savoy(Chief Executive Officer)Charla Howard(Chief Clinical Officer)Rebecca Gerth

Spike Gadgets manufactures specialized hardware for neuroscience research, including dataloggers, headstages, and electrode interface systems designed for neural signal recording in laboratory and animal research settings.

AI & Machine LearningBiotechDeep TechHardware

Mattias Karlsson(Co-founder and Chief Executive Officer)Magnus Karlsson(Co-founder and Chief Technology Officer)

BiotechSan Clemente, US

Derek Herrera(Executive Officer, Director)Christopher Jennings(Director)Bill Colone(Executive Officer, Director)Kenneth Baker(Director)

Co-investorsPAParticular VenturesSTStorm Industries InvestmentsSVSv Tech Ventures, Inc.

Spinogenix is a biopharmaceutical company developing therapies to restore synaptic function, with a pipeline aimed at neurological and neurodegenerative conditions.

BiotechDeep TechDigital HealthHealthtechLos Angeles, US

Stella Sarraf, Ph.D.(Executive Officer, Director)SSStella Sarraf(CEO, Founder, Director)inPVPeter Vanderklish(Chief Science Officer)inSGSharron Gargosky(Chief Development Officer)inRMRyan MacDonald(Chief Business Officer)SDSasha Damouni Ellis(Head of Investor Relations)

SPOC Biosciences develops a platform for affordable, scalable protein production and measurement of protein binding kinetics, serving researchers in drug development, synthetic biology, diagnostics, and proteomics.

AI & Machine LearningBiotechDeep TechMedical DevicesMenlo Park, US

Bharath Takulapalli(Founder & CEO)Mukilan Mohan(Co-Founder & COO)

Sporian manufactures high-temperature sensors and spectral analyzers for extreme environments, serving industries including energy generation, propulsion, manufacturing, and solar systems.

Advanced ManufacturingDeep TechHardwareSpace Tech

SportsGuard manufactures custom mouthguards using pressure lamination technology for athletes seeking protective dental equipment.

ConsumerDirect to ConsumerE-commerceHealthtechSports Tech

Spot Cells develops a device that selectively removes dead cells from cryopreserved neuronal cultures to improve data quality in drug toxicity and cell viability research.

BiotechDeep TechMedical Devices

HealthtechSan Francisco, US

ALEXANDER MARSON(Executive Officer, Director)PATRICK DAVID HSU(Director)JACOB CORN(Director)

BoardBBBLAKE BYERS(Director)in

Co-investorsTETeam Builder VenturesGVGV (Google Ventures)MAMagnetic Ventures

SPR develops the SPRINT PNS System, a peripheral nerve stimulation device for pain relief.

Digital HealthHardwareHealthtechMedical DevicesCleveland, US

Maria Bennett(President, CEO, and Founder)inJBJosh Boggs(Executive Officer)inMark Stulz(Executive Officer)Marilyn A. Eisele(Executive Officer)Ben Austin(Chief Financial Officer)inDYDavid Youngberg(Chief Commercial Officer)

Co-investorsAFAF WPartnersJUJumpstart VenturesMUMutual Capital PartnersNDNDIRCRC CapitalRERevelation Partners

Springbok Analytics uses MRI data to measure individual muscle volume, fat infiltration, and symmetry at the individual-muscle level with pixel-level precision.

AI & Machine LearningHealthtechSports TechCharlottesville, US

Joe H(Founder)

Co-investorsALAlumni VenturesANAnthropy PartnersCACartan CapitalTITitletownTech

Empath Labs creates technology and products designed to improve patient experience and support children in clinical research and healthcare settings.

BiotechDigital HealthHealthtechMedical Devices

AaronJoel

Square2 develops science-based digital therapeutic tools designed to help individuals change health behaviors and manage conditions like substance use disorders, depression, and chronic pain.

Digital HealthHealthtechMental HealthSaaSWellness & FitnessHanover, US

Lee Marsch

BiotechWatertown, US

Robert S. Langer, Sc.D.(Director)ASArmon Sharei, Ph.D.(Executive Officer, Director)ASArmon Sharei(Executive Officer, Director)Amy W. Schulman(Executive Officer, Director)Kris Elverum(Executive Officer)Howard Bernstein(Executive Officer)

Co-investorsALAlumni Ventures+N+ND CapitalGVGV (Google Ventures)ILIllumina VenturesINInvusJDJDRF T1D Fund+3 more

The company manufactures electro-optical modulators and optical sensors for applications requiring high-frequency signal processing and voltage measurement capabilities.

Deep TechHardwareMedical DevicesSemiconductors

Standard Imaging manufactures radiation calibration instruments for quality assurance in medical physics applications.

Advanced ManufacturingHardwareHealthtechMedical DevicesMiddleton, US

STARGATES is an engineering and technology company providing systems integration, cybersecurity, and software development services to federal and defense agencies as well as Fortune 500 companies.

CybersecurityDeep TechDefense TechEnterprise SoftwareArlington, US

Starship Health develops software frameworks and tools for behavioral public health, including local social-network smartphone apps, virtual role-playing tutors for communication skills training, and analytical tools for mapping and diagnosing care coordination cases.

AI & Machine LearningDigital HealthEdTechHealthtech

StataCorp develops Stata, a statistical analysis software used by professional researchers for data analysis.

AI & Machine LearningData & InfrastructureDeveloper ToolsEdTechSaaSCollege Station, US

Statera develops CIPS passive water samplers that accumulate a wide range of polar and non-polar organic chemicals over time to provide time-weighted average measurements of chemical exposure.

CleantechDeep TechHardware

STC Biologics is a contract development and manufacturing organization (CDMO) that takes biologic products from discovery through to commercialization, offering cell line development, cGMP drug substance production, and analytics for antibodies, bispecifics, and ADCs.

Advanced ManufacturingBiotechNewton, US

Steam Instruments develops high-spatial-resolution mass spectrometry technology, including ion detectors, ion imaging optics, and high-mass spectrometer designs for applications such as direct-from-tissue biomolecule mapping, ultra-high-mass biomolecule analysis, sub-micron hydrogen and lithium mapping, semiconductor dopant analysis, and nuclear forensics.

BiotechDeep TechHardware

StemCultures develops microencapsulation technology products for controlling growth factors in cell cultures, serving researchers working with stem cells, primary tumor cells, and organoids.

BiotechDeep TechHealthtechMedical Devices

Sally Temple(Co-founder)Jeff Stern(Co-founder)

StemBioSys develops cell culture technology, including the patented CELLvo Matrix that replicates the body's physiological microenvironment to expand mesenchymal stem cells and specialty cells while preserving their stem-like properties.

BiotechHealthtechLongevityMedical DevicesSan Antonio, US

CXChen Xiao-Dong(Director)SDSteven Davis(Co-founder)Xiao-Dong Chen(Co-founder)TBTravis Block(Chief Technology Officer)Jean Cheever(Director)Mark D Horsey(Executive Officer)

Co-investorsTATargeted Technology Funds

Stemina Biomarker Discovery develops in vitro assays using human stem cell-derived cells to predict drug toxicity and support drug discovery and development.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesMadison, US

EDElizabeth Donley(Co-founder)inGCGabriela Cezar(Co-founder)inRobert E. Burrier(Executive Officer)

BoardAndrew Ferrara(Director)R. Andrew Morgan(Director)Scott Carr(Director)

Stemloop developed cell-free and RNA synthetic biology into freeze-dried, programmable biosensors made from DNA, RNA, and protein for detecting contaminants such as lead in drinking water and other environmental settings.

BiotechCleantechDeep Tech

Khalid K. Alam(Co-founder)Julius B. Lucks(Co-founder)Michael C. Jewett(Co-founder)

StemMed provides patient-derived xenograft (PDX) models and related research materials for cancer research, serving biomedical researchers conducting studies at their own facilities.

BiotechDeep TechDigital HealthHealthtechMedical DevicesHouston, US

Dr. Tweardy(Head of the Division of Internal Medicine, Professor of Infectious Diseases and Molecular & Cellular Oncology)Michael Lewis(Associate Professor in the Departments of Molecular and Cellular Biology and Radiology)

Stepping Stones develops and operates community-based recovery programs for individuals struggling with substance abuse, offering residential services and peer support.

HealthtechImpact & Social GoodMental HealthWellness & FitnessHuntsville, US

Eric Richards(CEO)

Stingray is an oncology-focused biotech company developing drugs from discovery through clinical development to commercialization, led by scientists and physicians with experience in building oncology companies.

AI & Machine LearningBiotechHealthtechHouston, US

JNJonathan Northrup(Chief Executive Officer, Co-Founder)inSSSunil Sharma(Chief Medical Officer, Co-Founder)inScott Andrew Jordan(Executive Officer, Director, Promoter)

Co-investorsCACatalytic Impact FoundationGRGreen Park & Golf Ventures

Tempest provides mathematical and statistical modeling, optimization, and data management services to clients across health, life sciences, engineering, and logistics sectors.

Data & InfrastructureDeep TechEnterprise SoftwareGovTech

Stottler Henke develops AI-based software solutions for complex problem-solving, scheduling, training simulations, intrusion detection, and data visualization, serving defense, aerospace, and government agencies.

AI & Machine LearningDefense TechDeveloper ToolsEnterprise SoftwareGovTechSan Mateo, US

Andrea Stottler(Co-Founder and Director)Dick Stottler(Co-Founder and Director)inAndrea Henke Stottler(Founder)in

Co-investorsSTStartX

Streamline Automation provides engineering services and custom automation solutions for federal agencies and commercial clients, with specializations in nuclear power, process engineering, artificial intelligence, and rocket propulsion.

Advanced ManufacturingDeep TechDefense TechRoboticsHuntsville, US

Strykagen develops therapies, diagnostics, and biomarkers focused on muscular dystrophy and other rare muscle diseases, with applications in aging-related conditions.

BiotechHealthtechMedical DevicesReno, US

Dr. Dean J. Burkin(President and CEO)Dr. Ryan Wuebles(Chief Scientific Officer)David Maine(Chief Financial Officer)

Trig is an award-winning industrial design firm that helps consumer, healthcare, and durable goods companies develop products through comprehensive innovation processes spanning insights, branding, and product design.

ConsumerEnterprise SoftwareHealthtechMedical DevicesChapel Hill, US

Subtle Medical develops deep learning software for medical imaging that enables faster and safer image acquisition on existing scanners for healthcare providers and imaging centers.

AI & Machine LearningHealthtechMedical Devices

GZGreg Zaharchuk(Co-founder, MD, Ph.D., Neuroradiologist and Professor at Stanford)inEGEnhao Gong(Co-founder, Ph.D., Deep Learning Scientist)in

Co-investors3E3E Bioventures CapitalATAtinum Investment Co. Ltd.BEBessemer Venture PartnersBRBreyer CapitalDCDCVC (Data Collective)FOFoothill Ventures+12 more

CyberWerx provides cybersecurity and organizational resilience training, exercises, and facility space including immersive simulations of cyber and all-hazards threats.

CybersecurityDefense TechGovTechKodiak, US

Sun Nuclear manufactures quality assurance phantoms, detectors, and software for medical imaging and radiation therapy equipment testing in healthcare facilities.

AI & Machine LearningEnterprise SoftwareHardwareHealthtechMedical Devices

Sunnylife Pharma develops pharmaceuticals to address unmet medical needs in disease treatment, founded by former Merck scientists and collaborating with industry and academic partners globally.

BiotechHealthtechMedical DevicesNorth Brunswick, US

Veteran Merck scientists (group)

BiotechMedford, US

GTGiovanni Traverso(Director)inRobert Langer(Director)CSCarl Schoellhammer(Executive Officer, Director)inAmy Schulman(Director)

Co-investorsAXAxil CapitalTATaiwania Capital

Sur180 Therapeutics develops therapeutic treatments for endometriosis, a gynecological condition affecting millions of women, drawing on the team's decade of biomedical expertise in gastrointestinal physiology and clinical pharmacology.

BiotechDigital HealthFemTechMedical DevicesPonce, US

Annelyn Torres-Reveron(Co-Founder & CEO)Caroline B. Appleyard(Co-Founder & Scientific Director)Idhaliz Flores(Co-Founder & Chair of Scientific Board)

Surgisense develops smart sensing medical devices, including OxyView™ TC, which uses phosphorescent lifetime measurements to provide continuous, quantitative tissue oxygenation data from interstitial fluid.

Digital HealthHardwareMedical Devices

Jason Zand(President, CEO & Co-founder)Greg Fisher(Co-founder)

Surgivance develops digital pathology imaging technology for analyzing tissue samples with rapid image capture and without calibration requirements.

AI & Machine LearningHealthtechMedical Devices

Co-investorsPOPortland Seed Fund

Sus Clinicals provides preclinical testing services using its Oncopig cancer model, a large-animal platform that induces tumors and other diseases on demand to generate predictive data for medical devices, drugs, and diagnostics.

BiotechDeep TechHealthtechCincinnati, US

Lawrence Schook(Founder)inDr. Jessicca M. Rege(Chief Executive Officer)Stephen J Baggott(Executive Officer, Director)Geoffrey T Marshall(Executive Officer, Director)Jeffrey D Weedman(Executive Chair & Co-Founder)

SuviCa is a pharmaceutical company focused on discovering and developing small molecule therapeutics for cancer treatment, targeting a mechanism critical to cancer re-growth after standard therapies.

BiotechHealthtech

Tin Tin(Co-founder & Chief Scientific Officer)

Swallow Solutions develops products for people with dysphagia (difficulty swallowing), offering specially formulated beverages and desserts to meet hydration and nutrition needs and reduce choking risk, as well as medical devices for oropharyngeal strengthening therapy.

FoodTechHealthtechMedical DevicesMadison, US

JRJoAnne Robbins, Ph.D.(Director)Robert A. Carlson, M.D.(Executive Officer)EHEric H. Horler(Executive Officer, Director)Raymond Heller(Executive Officer)

BoardThomas G. Schuster(Director)Terence F. Kelly(Director)

SygnaMap uses spatial omics and AI-driven computational pathology to identify molecular biomarkers that map disease pathways, guide therapeutic targets, and monitor disease activity for rare and common diseases.

AI & Machine LearningBiotechDigital HealthSan Antonio, US

Sylvatica Bio develops organ and tissue preservation technologies, including supercooling methods that extend the viability of human organs such as livers outside the body.

BiotechDeep TechMedical Devices

SESebastian Eriksson Giwa, PhD(Founder)inMike Taylor(Founder)in

Co-investorsSTStartXTATaihill Venture

Symbios Technologies develops an energy-efficient aqueous plasma technology platform for water and wastewater treatment and recycling.

CleantechClimate TechDeep Tech

Symmetric Computing manufactures high-performance departmental supercomputers and mainframes with large shared memory and multi-core architectures at a fraction of traditional mainframe costs.

AI & Machine LearningDeep TechHardware

Symple Surgical develops microwave ablation medical devices for minimally invasive procedures, with a lead product, the DirectAblate GRIZZLY system, for treating Barrett's Esophagus and esophageal adenocarcinoma, plus a renal denervation system.

HardwareHealthtechMedical DevicesSacramento, US

Daniel J. Kasprzyk(Founder)Randy Preston(Co-founder)Gary Seelhorst(Chief Business Officer)Sohail Desai(Principal Engineering Leader)

Synbal is a biotech company using a proprietary "Active Genetics" gene-editing platform developed at UC San Diego to create humanized transgenic mouse and rat laboratory models expressing multiple human genes.

BiotechDeep TechSan Diego, US

Valentino Gantz(Board Member & Founder)Ethan Bier(Board Member & Founder)

Synedgen develops first-in-class glycomics-based regenerative therapeutics that repair mucosal injury and restore barrier function.

BiotechHealthtechClaremont, US

SBShenda Baker(Executive Officer, Director)inWilliam P. Wiesmann(Executive Officer, Director)inKaveri Parker(Executive Officer)inLSLaura Saward(Chief Executive Officer)in

BoardPaul C. Grint(Director)Hal Oien(Director)

Syntiron develops microbial vaccines targeting bacterial metal receptors to prevent infections including urinary tract infections, pneumonia, and sepsis.

BiotechDeep TechHealthtechSt Paul, US

Lisa Herron-Olson(Managing Director)Leah Randles(Senior Scientific Director)

Syntr Health Technologies makes the SyntrFuge System, an FDA-cleared device that automates the processing of autologous fat (microfat) for fat grafting, body contouring, and tissue healing.

BiotechHardwareHealthtechMedical DevicesIrvine, US

Ahmed Zobi(Executive Officer, Director)Hugo Salas(Director)Dane Shackleford(Director)

Revr (SynVitro Bio) designs functional proteins by combining AI models with large-scale biophysical data generated from an automated wet lab platform, using a closed-loop process to speed up protein refinement.

AI & Machine LearningBiotechDeep TechHealthtechSan Leandro, US

ZSZachary Sun(Executive Officer, Director)Michael Nemzek(Executive Officer, Director)Corinna Chen(CEO)

BoardFDFrancisco Dopazo(Director)in

Co-investorsHUHumboldt

Synvivia engineers molecules designed to reprogram cells.

AI & Machine LearningBiotechHealthtechSan Francisco, US

GLGabriel Lopez(CEO)in

Co-investorsCACAL InnovationCACalifornia Innovation FundCRCreative VenturesGAGaingelsMEMetaplanetTHThundermark Capital+5 more

System Biosciences develops tools for studying gene and protein function in complex biological systems, leveraging lentiviral vectors and reporter technologies.

BiotechDeep TechHealthtechMedical DevicesPalo Alto, US

Systems Technology, Inc. develops simulation products and human-machine interaction assessment solutions for aerospace, defense, and healthcare sectors.

AI & Machine LearningDeep TechDefense TechHardware

Duane T. McRuerIrving L. Ashkenas

T3D Therapeutics develops T3D-959, an oral drug candidate designed to treat Alzheimer's disease and other neurodegenerative disorders by targeting brain glucose and lipid metabolism.

BiotechHealthtechLongevityMedical Devices

John Didsbury, Ph.D.(President & CEO, Chairman of the Board)

Talus develops a proprietary platform that measures and modulates the regulome—the body's gene expression control system—in native cellular contexts.

AI & Machine LearningBiotechDeep TechHealthtechSeattle, US

AFAlex Federation(Founder)inLPLindsay Pino(Founder)inAlex Federation, Ph.D.(Chief Executive Officer & Co-Founder)Lindsay Pino, Ph.D.(Chief Technology Officer & Co-Founder)

BoardOAOmri Amirav-Drory(Director)inJSJ. Seth Strattan(Director)in

Co-investorsFAFarvatn VentureFIFifty YearsFUFundersClubGAGaingelsJUJude GomilaNFNFX+13 more

Shasqi is a biotech company developing pre-targeted cancer therapeutics using click chemistry to direct cancer drugs to tumors, aiming to improve efficacy while reducing dose-limiting toxicities.

BiotechHealthtechSan Francisco, US

José M. Mejía Oneto(CEO & Founder)

BiotechBranford, US

John Richard Nobile(Executive Officer, Director, Promoter)John Davidson(Executive Officer, Director, Promoter)

Co-investorsFRFreemind InvestmentsCOConnecticut InnovationsLELeading Edge Ventures

Targazyme develops and commercializes enzyme biopharmaceuticals designed to improve the delivery, tissue residence, and potency of therapeutic cells for treating cancers and serious auto-immune and neurodegenerative diseases.

BiotechMedical DevicesCarlsbad, US

Lynnet Koh(Founder)

Tasso develops diagnostic testing devices and platforms for home use, enabling patients to perform health monitoring and inform clinical decisions outside traditional healthcare settings.

Digital HealthHealthtechMedical DevicesSeattle, US

BCBen Casavant(Co-Founder and Chief Executive Officer)inEBErwin Berthier(Co-Founder and Chief Technology Officer)inALAlan Levy(Director)

BoardElizabeth Hambrecht(Director)PCPaul Conley(Director)in

Co-investorsFOForesite CapitalJ2J2 VenturesMEMerck Global Health Innovation FundMSMSD Global Health Innovation FundOMOMX VenturesRARA Capital+4 more

Tavo Biotherapeutics develops novel treatments for glaucoma and retinal diseases, focusing on disease-modifying therapies that target the root biological mechanisms of vision loss.

BiotechHealthtechMedical Devices

Co-investorsPUPureos BioventuresPOPolaris Partners

Reading Plus is an adaptive literacy instruction platform for schools that improves reading comprehension, fluency, and motivation through assessment-driven instruction grounded in decades of reading research.

EdTechSaaS

Earl TaylorJames TaylorCarl TaylorStanford TaylorMark Taylor

TDA Research develops commercial products and technologies in defense, aerospace, medical devices, materials science, and energy sectors.

Deep TechDefense TechEnergyMedical DevicesNew MaterialsGolden, US

Teachley develops math learning and intervention programs for students in grades K-5, using interactive lessons and games to build fact fluency, math strategies, problem-solving, and fraction skills.

EdTechNew York, US

Rachael Labrecque, PhD(Cofounder)inDPDana Pagar, PhD(Cofounder)inKara CArpenter, PhD(Cofounder)

Co-investorsDODorm Room

Technology Assessment and Transfer, Inc.

Advanced ManufacturingDeep TechDefense TechNew Materials

Endomimetics develops a BioNanomatrix coating technology for medical devices that mimics human tissue to reduce the need for additional surgeries and minimize complications from implanted devices.

BiotechDeep TechLongevityMedical Devices

Joseph N. Garner(Chief Executive Officer & Chairman)

Technovax appears to be a vaccine development company based on its advisory team composition, which includes leading virologists, pediatric infectious disease specialists, and vaccine development experts.

BiotechHealthtechNew York, US

Redwire is an integrated aerospace and defense company that builds space infrastructure, autonomous aircraft, and multi-domain systems for the space economy and for U.S. and allied military customers.

Defense TechHardwareSpace Tech

Teen Health Research develops online, evidence-based sexual and relationship health programs for adolescents.

Digital HealthEdTechHealthtechWellness & FitnessRaleigh, US

Dr. Laura Widman(Founder & CEO)

TEGA Therapeutics develops glycoscience-based therapies for life-threatening diseases, focusing on complex carbohydrates (glycans) as pharmaceutical targets.

Biotech

TSI develops mobile phone-based software for capturing and analyzing heart and lung sounds through auscultation, making diagnostic information available to healthcare providers in remote, resource-limited, and humanitarian settings.

AI & Machine LearningDigital HealthHealthtechMedical Devices

David Wolfson(CEO)

TeleSecurity Sciences develops AI-powered screening and imaging software solutions for aviation security, including threat detection systems and training platforms serving airport operators, equipment manufacturers, and government agencies globally.

AI & Machine LearningDeep TechDefense TechGovTechLas Vegas, US

Tempo Therapeutics is a biotechnology company developing therapeutics, with a focus that includes dermatology.

BiotechHealthtechMedical DevicesSan Diego, US

WWWestbrook Weaver(Founder & CEO)inDGDonald Griffin(Founder & CSO)SDStephanie Deshayes(VP R&D)Kwame Ulmer(Chief Regulatory Officer)PSPhilip Scumpia(VP of Medical Affairs, Dermatology)inEREric Richman(Executive Officer, Director)in

Co-investorsSUSugati Ventures

HealthtechLexington, US

Simon Williams(Executive Officer, Director)JHJohn Hartnett(Executive Officer)

BoardRBRichard B. Emmitt(Director)inEdward M. Giles(Director)Anthony J. Sinskey(Director)

Co-investorsTHThe Vertical GroupNONovartis Venture Fund

BiotechGermantown, US

Yong Chan Kim, PhD(Executive Officer, Director)Jihoon Park(Executive Officer, Director)

Tetracore provides reference materials and biological samples for research applications, including diagnostic reagents and viral agents used in laboratory and development settings.

AgTechBiotechDeep TechDefense TechHealthtechMedical DevicesMaryland, US

Tetra Discovery Partners (d/b/a Tetra Therapeutics) was a clinical-stage biopharmaceutical company whose clinical trials and research programs were acquired by Shionogi & Co., Ltd. in 2020 and are now managed by Shionogi's U.S. subsidiary.

Biotech

Co-investorsMIMichigan Capital NetworkDODolby Family Ventures

BiotechAustin, US

LBLaura Bosworth(Executive Officer, Director)Rick Schultz(Director)

Co-investorsCECentral Texas Angel Network

TF Instruments is a distributor of specialty x-ray equipment and components, including multilayer mirrors, single crystal reflectors, and compound refractive lenses, offering both products and consulting services for radiation instrumentation applications.

Advanced ManufacturingDeep TechHardwareSalinas, US

BiotechAustin, US

Brian Windsor(Executive Officer, Director)Kirk Coleman(Executive Officer)Robert S. Mills, Jr.(Executive Officer, Director)Aaron Fletcher(Director)

Mercury provides security technologies and system security engineering services for mission-critical aerospace and defense applications, including cryptography, secure boot, and physical protection solutions designed to prevent reverse engineering and protect against cyber threats.

CybersecurityDefense TechHardware

DNA Medicine Institute is a med-tech incubator and biomedical technology innovator that develops diagnostic systems, including its flagship rHEALTH platform, which compresses multiple lab assays into handheld devices validated in clinical, space, and austere environments.

BiotechDeep TechMedical DevicesSpace Tech

Eugene Y. Chan(President and Chief Scientist)

The Simple VUE provides enterprise-grade AI solutions and strategic consulting to help organizations leverage data for predictive intelligence and operational decision-making.

AI & Machine LearningCloud ComputingData & InfrastructureDeveloper ToolsEnterprise Software

Cicely Peace(President & CEO)Khai Edouard(Partner, Analytics Consultant)Suprit Patel(Strategic Partner)

BiotechSan Carlos, US

Miro Brajenovic(Executive Officer, Director)

TheraBionic develops a tumor-specific radiofrequency medical device (P1) for cancer treatment, administered non-invasively via a metal spoon applicator on the tongue.

BiotechDeep TechHealthtechMedical DevicesDetroit, US

Boris Pasche(CEO, Board Chair, Co-Founder)Alexandre Barbault(Co-Inventor)Valerie Pasche(Chief Operating Officer)Stefan Grant(General Counsel)

San Francisco, US

Kacie Neutz(Executive Officer, Director)Matthew L. Raggard(Executive Officer, Director)

BoardStephen Curtis(Director)Ameeth Sankaran(Director)

TheraNova is a venture studio and incubator that develops medical devices from concept through clinical trials, regulation, and commercialization using a shared R&D model.

BiotechHealthtechMedical DevicesSan Francisco, US

Co-investorsGRGreen Park & Golf Ventures

Therapeutic Vision develops Kinostat, a patented eye drop formulation designed to prevent diabetic eye complications in dogs by inhibiting the sorbitol pathway that causes lens and corneal damage.

BiotechHealthtechMedical DevicesOmaha, US

Developer of next-generation insulin solutions

BiotechWaban, US

Richard Berenson(Executive Officer, Director, Promoter)David C. Sweeney(Director)

BoardTXTim Xiao(Director)inJohn Brooks(Mr. Brooks is the Chairman of the Board of Directors.)

Co-investorsDEDelos CapitalRORobin Hood VenturesGRGreen Park & Golf VenturesJUJumpstart VenturesSASanofi Ventures

Thermogenesis manufactures cryopreservation and cell processing systems for cord blood banking and cellular therapy applications in the biotechnology and healthcare sectors.

Advanced ManufacturingBiotechHealthtechMedical DevicesRancho Cordova, US

Thetis is a clinical-stage pharmaceutical company developing TP-317, an oral Resolvin E1 drug that activates the BLT1 receptor to restore tissue and immune balance.

BiotechHealthtechSouthport, US

FCFrank C Sciavolino(Manager)inGMGary Mathias(Co-Founder & CEO)inJPJohn Parkinson(Chief Science Officer)JSJoyce Steinberg(Chief Medical Officer)

BoardDavid M Wurzer(Manager)Alan Mendelson(Manager)

Co-investorsCOConnecticut InnovationsFRFreemind Investments