Palo Santo
Venture capitalActively deployingHighland Park · 4 people tracked
Also known as Palo Santo Investors · Palo Santo VC
Find your way into Palo Santo
575 people in our graph share verified history with the Palo Santo team — schools, employers, funds. One of them is your warm intro.
Fund manager profile
Palo Santo is a venture fund manager based in Highland Park. SEC filings show 3 venture funds on record, most recently Palo Santo Investors II LP filed February 2026.
Source: SEC EDGAR Form D filings. Firm website data not yet available.
Team · 4 people
from public directories
What they invest in
from 4 of 4 portfolio companiesDigital Health ×4Biotech ×3AI & Machine Learning ×2Medical Devices ×2Healthtech ×1Mental Health ×1
HQs:United States×1
Investments · 4 tracked
founders shown can be your intro pathBy year:2022 · 12021 · 23 dated
Delix Therapeutics develops third-generation, non-hallucinogenic neuroplastogens for people with neurological conditions, using a discovery platform to identify novel compounds.
BiotechDigital HealthMedical Devices
Co-investorsArtis VenturesCasa Verde CapitalNoeticOMX VenturesPsyMed VenturesRA Capital+6 more
Gilgamesh Pharmaceutical develops novel chemical entities for psychiatric disorders using medicinal chemistry and AI-powered translational platforms to design rapid-acting therapies targeting neurobiological mechanisms rather than symptom management.
AI & Machine LearningBiotechDigital HealthHealthtechNew York City, US
Jonathan Sporn(Founder)inAndrew Kruegel(Founder)inDalibor Sames(Founder)inJONATHAN SPORN(Founder)inAndrew Kruegel, Ph.D.(Executive Officer)Jonathan Sporn, M.D.(President and Chief Executive Officer)in
Co-investorsAera VCFrontera Technology VenturesFrontier Path VCJames Beshara FundJLSMagnetic Ventures+9 more
Journey Clinical provides ketamine-assisted psychotherapy (KAP) for depression, anxiety, and PTSD, partnering patients with licensed therapists and medical teams while coordinating with major insurance providers.
Digital HealthMedical DevicesMental Health
Jonathan Sabbagh(Co-founder & Executive Chairman of the Board)inMyriam Barthes(Co-founder & CEO)in
Co-investorsAble PartnersAlleyCorpCoalition OperatorsFifty YearsMantis CapitalPROOF+5 more
Syndeio Biosciences is a synapse-focused biotech developing precision neurotherapeutics for neuropsychiatric, mental health, and cognitive disorders such as depression and Alzheimer's.
AI & Machine LearningBiotechDigital Health
Co-investorsEvolution VC PartnersTenmileCatalio Capital Management
Portfolio news
latest coverage across their companies
Gilgamesh Pharmaceuticals · wmbdradio.com · Jul 16, 2026
Syndeio Biosciences · cen.acs.org · Nov 10, 2025
Delix · ucdavis.edu · Sep 10, 2025
Frequently asked questions
- Where is Palo Santo located?
- Palo Santo is headquartered in Highland Park, US.