San Francisco · Seed–Series A · 5 people tracked
Also known as LIONHEART FUND MANAGEMENT LLC
Find your way into LIONHEART VENTURES
939 people in our graph share verified history with the LIONHEART VENTURES team — schools, employers, funds. One of them is your warm intro.
Investment thesis
Lionheart Ventures backs exceptional, ethical, growth-oriented founders building transformative technologies with the potential to impact humanity at scale while generating attractive returns. The firm concentrates on two areas: artificial intelligence — favoring technologies that defend and enhance human flourishing, agency, and resilience — and frontier mental health, including psychedelic medicine and neuromodulation that can improve today's standard of care. Composed of former founders who have raised from leading VCs and built companies to exit, the firm emphasizes intellectual honesty, ethical conduct, and counterfactual impact, and aims to help guide responsible stewardship of humanity's most transformative technologies.
Source: firm website, verified Sep 15, 2026.
Team · 5 people
from public directories
Founder mafia
3 people who came through LIONHEART VENTURES went on to found or lead other companies.
What they invest in
from 18 of 21 portfolio companiesBiotech ×7Digital Health ×6Healthtech ×6Mental Health ×6Deep Tech ×5Medical Devices ×5AI & Machine Learning ×4Wellness & Fitness ×4
HQs:United States×6Canada×1United Kingdom×1India×1Singapore×1
Who they back
founder profiles across 8 portfolio companiesFounding team size:solo founder×32 founders×24+ founders×3
Where their founders studiedfrom 14 founders with education data
Yale University ×3Stanford University ×2Wesleyan University ×2
What their founders studiedfrom 14 founders with field-of-study data
Computer Science ×5Physics ×4Humanities ×3
Where their founders worked beforefrom 17 founders with career history
OpenAI ×7Stanford University ×2
Investments · 21 tracked
founders shown can be your intro pathBy year:2025 · 12022 · 12021 · 32020 · 16 dated
Piramidal bridges in-vivo and in-silico intelligence for neuroscience research and clinical applications.
AI & Machine LearningBiotechHealthtechMedical DevicesNew York City, US
Dimitris Fotis Sakellariou(Founder)inKris Pahuja(Founder)in
Co-investorsY CombinatorAdverb Venturesfutureland venturesGeek VenturesRitual CapitalVirta Ventures
2AB BioscienceS develops first-in-class small molecule therapeutics targeting the 5-HT2A receptor for ophthalmology and central nervous system disorders.
BiotechDeep TechDigital HealthMedical DevicesSanta Monica, US
Alex Speiser(Co-Founder & Chief Executive Officer)inCharles Nichols, PhD(Co-Founder & Chief Science Officer)David Nichols, PhD(Co-Founder & Head of Chemistry)Tim Foster, PhD(Co-Founder & Head of Translational Discovery)
BoardGopal Das(Director)
Anthropic is an AI safety research company that builds reliable, interpretable, and steerable AI systems.
AI & Machine LearningDeep TechDeveloper ToolsEnterprise SoftwareSan Francisco, US
Dario Amodei(Co-founder & CEO)inDaniela Amodei(Co-founder & President)inTom Brown(Co-founder)inJack Clark(Co-founder & Head of Policy)inJared Kaplan(Co-founder & Chief Science Officer)inChris Olah(Co-founder & Interpretability Research Lead)in
Co-investors3Comma Capital7BC Venture CapitalA.Capital VenturesAccelAlkeon InnovationAllen Institute for AI (AI2) Incubator+85 more
Beam is a shared micromobility operator providing electric scooter services across Asia Pacific cities, committed to climate neutrality and Vision Zero safety standards through technology and rider education programs.
Climate TechMobility & TransportationSingapore, SG
Deb Gangopadhyay(Founder)inAlan Jiang(Founder)in
Co-investorsAppWorks VenturesArbor VenturesGobi PartnersIndex VenturesK2 GlobalPartech Ventures+4 more
Bodhi is a mobile app that connects users in India with verified astrologers, tarot readers, and numerologists for online consultations via chat or call.
ConsumerMarketplacesWellness & Fitness
Co-investorsUpsparks Capital
Calm is a mental health app offering guided meditations, sleep stories, soundscapes, and stress-relief tools designed to help users manage anxiety, improve sleep, and build healthy habits for overall wellness.
HealthtechMental HealthWellness & Fitness
David Ko(CEO)
Co-investorsAcumen AmericaBrighter CapitalCherubic VenturesConnect VenturesElefundEQUIAM+18 more
Carbon Crusher repairs roads using carbon-binding biopolymers and recycled road materials to create stronger, longer-lasting sustainable roads.
CleantechClimate TechConstruction Tech
Co-investors10xvaluepartners
Charm Industrial converts agricultural residues into bio-oil and injects it underground to remove carbon from the atmosphere at scale.
AgTechCleantechClimate Tech
Shaun Meehan(Chief Scientist and co-founder)in
Co-investorsAzolla VenturesBreyer CapitalCongruent VenturesKinnevikPrime Impact FundSystemiq Capital+8 more
Clerkenwell Health operates specialized clinical trial sites focused on neuropsychiatric and CNS conditions, including psychedelic-assisted therapy research and trials for depression, anxiety, dementia, and neurodegenerative disorders.
BiotechDigital HealthHealthtechMedical DevicesMental HealthLondon, GB
Dr Simon G.D. Ruffell(Principal Investigator & Sub-Investigator)Dr Paul Morrison(Principal Investigator)Dr Henry Fisher(CSO)Tom McDonald(CEO)Sam Lewis(CFO)George McBride(CCO)
Co-investorsExceptional VenturesMoonstone Venture Capital
Cognigenics is developing iRNAi, a non-invasive intranasal RNA interference platform that delivers programmable RNA therapeutics directly to targeted brain circuits, bypassing the blood-brain barrier to modulate mood, memory, and cognition.
BiotechDeep TechDigital HealthEagle, US
John Mee(Mr. Mee is a promoter, director and officer of the company.)J.L. Mee(Founder)inBarry Linder(Executive Officer, Director, Promoter)Dean Radin(Executive Officer, Director, Promoter)
World leader in drone-based restoration of degraded land
Matthew Ritchie(Founder)in
Co-investorsAt One VenturesLOWERCARBONLowercarbon CapitalSystemiq CapitalVentureSouqZouk Capital+4 more
Dimensions Retreats operates therapeutic retreat centers combining neuroscientific research and evidence-based somatic therapy with luxury accommodations in natural settings, focusing on mental health and well-being.
HealthtechMental HealthTravel & HospitalityWellness & FitnessKingston, CA
Chris(Founder and CEO)
Journey Clinical provides ketamine-assisted psychotherapy (KAP) for depression, anxiety, and PTSD, partnering patients with licensed therapists and medical teams while coordinating with major insurance providers.
Digital HealthMedical DevicesMental Health
Jonathan Sabbagh(Co-founder & Executive Chairman of the Board)inMyriam Barthes(Co-founder & CEO)in
Co-investorsAble PartnersAlleyCorpCoalition OperatorsFifty YearsMantis CapitalPROOF+5 more
Psychedelic therapies for addiction.
BiotechSan Francisco, US
Jeeshan Chowdhury(Executive Officer, Director, Promoter)in
BoardSam Altman(Director)Krishna Kantheti(Director)
Co-investorsMBX CapitalAPOLLO PROJECTS
Lucid Computing builds hardware-encrypted compute clusters with verifiable AI audit trails for enterprises and institutions requiring confidentiality and regulatory compliance.
AI & Machine LearningCloud ComputingCybersecurity
Kristian Rönn(Founder)in
Co-investorsJuniper Ventures Management, Llc
NeuroBionics develops soft, flexible neural interface technologies for neuromodulation applications.
BiotechDeep TechHealthtechMedical DevicesSomerville, US
MJ Antonini(Founder, CEO)inNicki Driscoll(Founder, CTO)Polina Anikeeva(Founder)in
Co-investorsFuture VenturesGreyMatterVanedge CapitalVanedge Capital Limited PartnershipDolby Family Ventures
Reconnect Labs develops precision neuropsychiatry approaches to treat sleep, anxiety, and addiction disorders, drawing on clinical drug development and psychiatric research.
BiotechDigital HealthHealthtechMental Health
Michael Kometer(Board Chairman & Co-founder)in
Softmax builds AI systems based on organic alignment principles—the concept that agents remaining aligned with human values also maintain alignment with each other.
AI & Machine LearningDeep TechSector Agnostic
Emmett Shear(CEO & Founder)inDavid Bloomin(Founder)inYatharth Agarwal(Cofounder)inAdam Goldstein(Board Member and Founder Emeritus)in
Co-investorsJuniper Ventures Management, LlcLifelike CapitalMythos Ventures Management, LlcNight CapitalSancus VenturesSummit Peak Investments+2 more
Wavepaths develops adaptive therapeutic music designed to support mental health and wellness practitioners in their sessions.
Digital HealthMental HealthWellness & Fitness
Mendel Kaelen(Founder & CEO)in
Co-investorsMITONReflex CapitalNeo Kuma VenturesPalo Santo
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Bexson BiomedicalCausative Labs
Portfolio news
latest coverage across their companies
Anthropic · techcrunch.com · Sep 15, 2026
Calm · funderintel.com · Jul 16, 2026
Beam · tipranks.com · Jun 27, 2026
Charm Industrial · trysignalbase.com · Jun 12, 2026
NeuroBionics · newmarketpitch.com · Feb 18, 2026
Softmax · corememory.com · Mar 28, 2025
Frequently asked questions
- How many investments has LIONHEART VENTURES made?
- LIONHEART VENTURES has 21 tracked investments, including 1 dated in the last 24 months.
- What stage does LIONHEART VENTURES invest at?
- LIONHEART VENTURES invests at the Seed, Series A stages.
- What sectors does LIONHEART VENTURES focus on?
- LIONHEART VENTURES focuses on AI & Machine Learning, Mental Health.
- Where is LIONHEART VENTURES located?
- LIONHEART VENTURES is headquartered in San Francisco, US.
- Who does LIONHEART VENTURES co-invest with?
- LIONHEART VENTURES most often shares deals with Juniper Ventures Management, Llc, Breyer Capital, Cherubic Ventures, among 50 tracked co-investors.
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