San Francisco · Seed–Series A · 6 people tracked
Also known as LIONHEART FUND MANAGEMENT LLC
Investment thesis
Lionheart Ventures backs exceptional, ethical, growth-oriented founders building transformative technologies with the potential to impact humanity at scale while generating attractive returns. The firm concentrates on two areas: artificial intelligence — favoring technologies that defend and enhance human flourishing, agency, and resilience — and frontier mental health, including psychedelic medicine and neuromodulation that can improve today's standard of care. Composed of former founders who have raised from leading VCs and built companies to exit, the firm emphasizes intellectual honesty, ethical conduct, and counterfactual impact, and aims to help guide responsible stewardship of humanity's most transformative technologies.
Source: firm website, verified Aug 25, 2026.
Team · 6 people
from public directories
Founder mafia
2 people who came through LIONHEART VENTURES went on to found or lead other companies.
What they invest in
from 15 of 17 portfolio companiesBiotech ×5Deep Tech ×5Healthtech ×5AI & Machine Learning ×4Mental Health ×4Climate Tech ×3Digital Health ×3Medical Devices ×3
HQs:United States×4India×1Singapore×1
Investments · 17 tracked
founders shown can be your intro pathBy year:2025 · 12022 · 12 dated
Piramidal bridges in-vivo and in-silico intelligence for neuroscience research and clinical applications.
AI & Machine LearningBiotechHealthtechMedical DevicesNew York City, US
Dimitris Fotis Sakellariou(Founder)inKris Pahuja(Founder)in
Co-investorsY CombinatorAdverb Venturesfutureland venturesGeek VenturesRitual Capital
2A Biosciences is a stealth-stage biotech developing precision 5-HT2A receptor agonists that activate the body's intrinsic regenerative pathways for nerve regeneration and reduced inflammation.
BiotechDeep TechMedical Devices
Anthropic is an AI safety research company that builds reliable, interpretable, and steerable AI systems.
AI & Machine LearningDeep TechDeveloper ToolsEnterprise SoftwareSan Francisco, US
Dario Amodei(Co-founder & CEO)inDaniela Amodei(Co-founder & President)inTom Brown(Co-founder)inJack Clark(Co-founder & Head of Policy)inJared Kaplan(Co-founder & Chief Science Officer)Chris Olah(Co-founder & Interpretability Research Lead)
Co-investors3Comma Capital7BC Venture CapitalA.Capital VenturesAccelAlkeon InnovationAllen Institute for AI (AI2) Incubator+85 more
Beam is a shared micromobility operator providing electric scooter services across Asia Pacific cities, committed to climate neutrality and Vision Zero safety standards through technology and rider education programs.
Climate TechMobility & TransportationSingapore, SG
Deb Gangopadhyay(Founder)Alan Jiang(Founder)
Co-investorsAppWorks VenturesArbor VenturesGobi PartnersIndex VenturesK2 GlobalPartech Ventures+3 more
Co-investorsNoeticPsyMed Ventures
Bodhi is a mobile app that connects users in India with verified astrologers, tarot readers, and numerologists for online consultations via chat or call.
ConsumerMarketplacesWellness & Fitness
Co-investorsUpsparks Capital
Calm is a mental health app offering guided meditations, sleep stories, soundscapes, and stress-relief tools designed to help users manage anxiety, improve sleep, and build healthy habits for overall wellness.
HealthtechMental HealthWellness & Fitness
David Ko(CEO)
Co-investorsBrighter CapitalCherubic VenturesConnect VenturesElefundEQUIAMEvio VC+17 more
Carbon Crusher recycles existing road material by mixing it with a plant-based BioBinder using autonomous crushing equipment to build stronger, longer-lasting road bases without new resources.
CleantechClimate TechConstruction Tech
Co-investors10xvaluepartners
Charm Industrial converts agricultural residues into bio-oil and injects it underground to remove carbon from the atmosphere at scale.
AgTechCleantechClimate Tech
Shaun Meehan(Chief Scientist and co-founder)
Co-investorsAzolla VenturesBreyer CapitalCongruent VenturesKinnevikPrime Impact FundSystemiq Capital+6 more
Clerkenwell Health runs clinical trials for mental health and neurological conditions such as depression, anxiety, and PTSD, recruiting participants and offering a clinical trial network for CNS research.
Digital HealthHealthtechMental Health
Co-investorsExceptional VenturesMoonstone Venture Capital
Cognigenics is developing iRNAi, a non-invasive intranasal RNA interference platform that delivers programmable RNA therapeutics directly to targeted brain circuits, bypassing the blood-brain barrier to modulate mood, memory, and cognition.
BiotechDeep TechDigital HealthEagle, US
John Mee(Mr. Mee is a promoter, director and officer of the company.)Barry Linder(Executive Officer, Director, Promoter)Dean Radin(Executive Officer, Director, Promoter)
Lucid Computing builds hardware-encrypted compute clusters with verifiable AI audit trails for enterprises and institutions requiring confidentiality and regulatory compliance.
AI & Machine LearningCloud ComputingCybersecurity
Kristian Rönn(Founder)in
Co-investorsJuniper Ventures Management, Llc
NeuroBionics develops soft, flexible neural interface technologies for neuromodulation applications.
BiotechDeep TechHealthtechMedical DevicesSomerville, US
MJ Antonini(Founder, CEO)Nicki Driscoll(Founder, CTO)Polina Anikeeva(Founder)
Co-investorsFuture VenturesGreyMatterVanedge CapitalVanedge Capital Limited PartnershipDolby Family Ventures
Reconnect Labs develops precision neuropsychiatry approaches to treat sleep, anxiety, and addiction disorders, drawing on clinical drug development and psychiatric research.
BiotechDigital HealthHealthtechMental Health
Michael Kometer(Board Chairman & Co-founder)in
Softmax builds AI systems based on organic alignment principles—the concept that agents remaining aligned with human values also maintain alignment with each other.
AI & Machine LearningDeep TechSector Agnostic
Emmett Shear(CEO & Founder)inDavid Bloomin(Founder)inYatharth Agarwal(Cofounder)inAdam Goldstein(Board Member and Founder Emeritus)in
Co-investorsJuniper Ventures Management, LlcLifelike CapitalMythos Ventures Management, LlcNight CapitalSancus VenturesSummit Peak Investments+2 more
Portfolio news
latest coverage across their companiesAnthropic · Reuters · Aug 15, 2026
Calm · funderintel.com · Jul 16, 2026
Beam · tipranks.com · Jun 27, 2026
Charm Industrial · trysignalbase.com · Jun 12, 2026
NeuroBionics · newmarketpitch.com · Feb 18, 2026
Softmax · corememory.com · Mar 28, 2025
Frequently asked questions
- How many investments has LIONHEART VENTURES made?
- LIONHEART VENTURES has 15 tracked investments.
- What stage does LIONHEART VENTURES invest at?
- LIONHEART VENTURES invests at the Seed, Series A stages.
- What sectors does LIONHEART VENTURES focus on?
- LIONHEART VENTURES focuses on AI & Machine Learning, Mental Health.
- Where is LIONHEART VENTURES located?
- LIONHEART VENTURES is headquartered in San Francisco, US.
- Who does LIONHEART VENTURES co-invest with?
- LIONHEART VENTURES most often shares deals with Juniper Ventures Management, Llc, Breyer Capital, Cherubic Ventures, among 49 tracked co-investors.
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