LIONHEART VENTURES
Venture capitalActively deployingSan Francisco · Seed–Series A · 5 people tracked
Also known as LIONHEART FUND MANAGEMENT LLC
Investment thesis
Lionheart Ventures backs exceptional, ethical, growth-oriented founders building transformative technologies with the potential to impact humanity at scale while generating attractive returns. The firm concentrates on two areas: artificial intelligence — favoring technologies that defend and enhance human flourishing, agency, and resilience — and frontier mental health, including psychedelic medicine and neuromodulation that can improve today's standard of care. Composed of former founders who have raised from leading VCs and built companies to exit, the firm emphasizes intellectual honesty, ethical conduct, and counterfactual impact, and aims to help guide responsible stewardship of humanity's most transformative technologies.
Source: firm website, verified Aug 3, 2026.
Team · 5 people
from public directoriesWhat they invest in
from 9 of 16 portfolio companiesAI & Machine Learning ×4Biotech ×3Healthtech ×3Climate Tech ×2Deep Tech ×2Mental Health ×2AgTech ×1Cleantech ×1
HQs:United States×3
Investments · 16 tracked
founders shown can be your intro pathAnthropic is an AI safety research company that builds reliable, interpretable, and steerable AI systems.
AI & Machine LearningDeep TechSan Francisco, US
Dario AmodeiDaniela Amodei
Calm is a mental health app offering guided meditations, sleep stories, soundscapes, and stress-relief tools designed to help users manage anxiety, improve sleep, and build healthy habits for overall wellness.
HealthtechMental HealthWellness & Fitness
David Ko(CEO)
Charm Industrial converts agricultural residues into bio-oil and injects it underground to remove carbon from the atmosphere at scale.
AgTechCleantechClimate Tech
Shaun Meehan(Chief Scientist and co-founder)
BiotechEagle, US
John Mee(Mr. Mee is a promoter, director and officer of the company.)Barry Linder(Executive Officer, Director, Promoter)Dean Radin(Executive Officer, Director, Promoter)
Softmax builds AI systems based on organic alignment principles—the concept that agents remaining aligned with human values also maintain alignment with each other.
AI & Machine LearningDeep TechSector Agnostic
Emmett Shear(Founder & Lead)inDavid Bloomin(Founder)inYatharth Agarwal(Cofounder)in
Lucid Computing builds hardware-encrypted compute clusters with verifiable AI audit trails for enterprises and institutions requiring confidentiality and regulatory compliance.
AI & Machine LearningCloud ComputingCybersecurity
Reconnect Labs develops precision neuropsychiatry approaches to treat sleep, anxiety, and addiction disorders, drawing on clinical drug development and psychiatric research.
BiotechDigital HealthHealthtechMental Health
Michael Kometer(Board Chairman & Co-founder)
Frequently asked questions
- What stage does LIONHEART VENTURES invest at?
- LIONHEART VENTURES invests at the Seed, Series A stages.
- What sectors does LIONHEART VENTURES focus on?
- LIONHEART VENTURES focuses on AI & Machine Learning, Mental Health.
- Where is LIONHEART VENTURES located?
- LIONHEART VENTURES is headquartered in San Francisco, US.
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