About
Dario Doller is Chief Scientific Officer at Modulate Bio, with expertise in allosteric drug discovery targeting GPCRs, ion channels, and enzymes for CNS, metabolic, and cardiovascular indications. Over a 30-year career in pharma and biotech, he contributed to the FDA-approved drug Vorapaxar and to four additional clinical-stage compounds (CTP-692, NGD-4715, and Lu AF09535), and edited two books, Allosterism in Drug Discovery (RSC, 2017) and Trends in CNS Drug Discovery (Wiley, 2025). His background spans medicinal chemistry, CNS chemical biology, pharmacokinetics, and in vitro and in vivo pharmacology.
Co-founder at Modulate Bio
Intro paths
In turn, Dario can intro founders to Modulate Bio's investors below.
Modulate Bio's investors · 1
Co-founders at Modulate Bio

Experience
- Modulate BioChief Scientific Officer (CSO)current2023 — presentMassachusetts, United States
- Nabu TherapeuticsVP of Medicinal Chemistrycurrent2025 — presentSan Francisco Bay Area
- Babylon BiosciencesDiscovery Teamcurrent2025 — presentSan Francisco Bay Area
- Alcyoneus ScienceWorksEarly discovery consulting2015 — 2025NJ, USA
- iNeuro Therapeutics IncVP Chemistry2022 — 2023Cambridge, Massachusetts, United States
- Lucy TherapeuticsVP, Drug Discovery2021 — 2022Cambridge, Massachusetts, United States
- Sunovion PharmaceuticalsDirector, Medicinal Chemistry2019 — 2021Marlborough, MA
- Sage TherapeuticsSenior Director, Head of Exploratory Research2017 — 2019Cambridge, MA
- CoNCERT Pharmaceuticals, Inc.Senior Director, Deuterium Platform2016 — 2017Greater Boston
- LundbeckChemical Biology, Global Head2014 — 2015Paramus, NJ
- LundbeckDirector, Global Project Leader (Discovery Chemistry & DMPK Department)2011 — 2014Paramus, NJ
- LundbeckDirector, Medicinal Chemistry (Chemical and Pharmacokinetic Sciences Department)2010 — 2011
- LundbeckDirector, Medicinal Chemistry2006 — 2010
- Neurogen CorporationAssociate Director2000 — 2006
- GliatechSenior Scientist1999 — 2000
- 3-Dimensional PharmaceuticalsGroup Leader1998 — 1999
- Schering-Plough Research InstituteSenior Scientist1994 — 1998
- Rohm and HaasResearch Scientist1992 — 1994Springhouse, PA
- Texas A&M UniversityPost-doc1989 — 1992
Skills & more
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Drug DesignPharmacologyDrug DevelopmentBiotechnologyChemistryNeuroscienceDMPKPharmacokineticsGPCRsAssay DevelopmentCollaborative Problem SolvingCreative SolutionsLanguages Spanish
From Dario's professional profile.
Frequently asked questions
- Who is Dario Doller?
- Dario Doller is Chief Scientific Officer at Modulate Bio, with expertise in allosteric drug discovery targeting GPCRs, ion channels, and enzymes for CNS, metabolic, and cardiovascular indications. Over a 30-year career in pharma and biotech, he contributed to the FDA-approved drug Vorapaxar and to four additional clinical-stage compounds (CTP-692, NGD-4715, and Lu AF09535), and edited two books, Allosterism in Drug Discovery (RSC, 2017) and Trends in CNS Drug Discovery (Wiley, 2025). His background spans medicinal chemistry, CNS chemical biology, pharmacokinetics, and in vitro and in vivo pharmacology.
- Where does Dario Doller work?
- Dario Doller is Co-founder of Modulate Bio.
- What companies did Dario Doller found?
- Dario Doller founded Modulate Bio.
- Where did Dario Doller go to school?
- Dario Doller studied at University of Buenos Aires (Doctor of Philosophy - PhD, Chemical Sciences); University of Buenos Aires (Licentiate degree, Organic Chemistry).
Founder mafias
University of Buenos Aires mafia26
Also came through, then founded or led a company.
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Same school
Also attended University of Buenos Aires119
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Shared employers
Also worked at Lucy Therapeutics1
Also worked at Sunovion Pharmaceuticals2
Also worked at Sage Therapeutics6
Also worked at Schering-Plough Research Institute10
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