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Kaleida Capital

Venture capitalActively deploying

San Diego · 14 people tracked

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Investment thesis

Kaleida Capital invests in the neurotechnology of tomorrow, focusing on neural data infrastructure, human performance, and artificial intelligence. The firm views the brain as the next major platform across life science and technology, backing founders at the intersection of brain science and AI. Its high-conviction portfolio spans neural engineering, brain-computer interfaces, and deep AI applications, targeting four themes: precision medicine (personalized therapies and diagnostics), human performance (cognitive and physical enhancement, mental health), digital interfaces (communication, productivity, entertainment), and AI and computation. The team combines deeptech operators, scientists, and policy architects to identify and support promising neurotechnology founders.

Source: firm website, verified Aug 3, 2026.

HQ
San Diego, US
Instruments
Equity
Founded
2025
Tracked investments
16

Team · 14 people

from the firm's website & curated

Founder mafia

2 people who came through Kaleida Capital went on to found or lead other companies.

What they invest in

from 8 of 16 portfolio companies

Medical Devices ×5AI & Machine Learning ×4Biotech ×4Deep Tech ×4Healthtech ×3Digital Health ×2Enterprise Software ×2Hardware ×2

HQs:United States×7

Who they back

founder profiles across 5 portfolio companies
55%
repeat founders
of 11 founders with career history

Where their founders worked beforefrom 11 founders with career history

OpenAI ×5Stanford University ×2Stripe ×2

Investments · 16 tracked

founders shown can be your intro path
Anthropicanthropic.comin𝕏

Anthropic is an AI safety research company that builds reliable, interpretable, and steerable AI systems.

AI & Machine LearningDeep TechDeveloper ToolsEnterprise SoftwareSan Francisco, US

Dario Amodei(Co-founder & CEO)inDaniela Amodei(Co-founder & President)inTom Brown(Co-founder)inJack Clark(Co-founder & Head of Policy)inJared Kaplan(Co-founder & Chief Science Officer)Chris Olah(Co-founder & Interpretability Research Lead)

PartnerAriane Tom· led

Co-investors3Comma Capital7BC Venture CapitalA.Capital VenturesAccelAlkeon InnovationAllen Institute for AI (AI2) Incubator+85 more

Anthropic
Aurenaraurenar.com

Aurenar develops a non-invasive, ear-worn neuromodulation wearable that stimulates a nerve in the ear to boost the body's natural control of inflammation, targeting complications in intensive care unit patients.

HardwareHealthtechMedical Devices

Eric Leuthardt(Chief Executive Officer & Founder)inJenna Gorlewicz(Chief Technology Officer & Founder)inAnna Huguenard(Chief Medical Officer & Founder)inJesse Wheeler(Chief Operations Officer)inRyan Kight(Chief Financial Officer)in

PartnerAriane Tom· led

Co-investorsDeep FutureSolas BioVentures

Clinical-Stage Endovascular Brain-Computer Interface
Computational Neuroimaging Platform
High-Bandwidth Brain-Computer Interface
Manifest Technologiesmanifesttech.ioin

Manifest Technologies develops the NAIO computational neuroimaging platform, which uses AI to integrate and analyze multi-modal neuroimaging data for biomarker discovery, target validation, and patient selection.

AI & Machine LearningBiotechDigital Health

Co-investorsConnecticut Innovations

Neurotechnology Platform
OpenAIopenai.comin𝕏

OpenAI is an AI research and deployment company focused on developing artificial general intelligence (AGI) with emphasis on safety and beneficial outcomes for humanity.

AI & Machine LearningCloud ComputingEnterprise SoftwareSan Francisco, US

Sam Altman(Co-founder & CEO)Elon Musk(Co-founder & former Co-chair / board member)Greg Brockman(Co-founder & President)inIlya Sutskever(Co-founder & Chief Scientist)inWojciech Zaremba(Co-founder)inJohn Schulman(Co-founder (departed 2024))

PartnerAriane Tom· led

Co-investorsA.Capital VenturesA'Z AngelsAdvent InternationalAlpha Wave GlobalAndreessen HorowitzAnti+54 more

Paradromics Turning Data Into Medicineparadromics.comin𝕏

Paradromics develops a brain-computer interface (BCI) system, with FDA Breakthrough Device Designations for speech decoding and digital device control, and works with academic medical institutions on translational BCI research.

BiotechDeep TechHealthtechMedical DevicesAustin, US

Matt Angle(Founder and CEO)in

Co-investors15th RockAlpha EdisonAnthropy PartnersCapital FactoryCoastCapFrontier Path VC+14 more

Resonant Link Medicalrlmedical.comin

Resonant Link Medical develops wireless power and data transfer technology for implantable medical devices, enabling smaller, rechargeable, or battery-free implants.

HardwareHealthtechMedical DevicesSouth Burlington, US

Omari Bouknight(Executive Officer, Director)

BoardJeffrey Chu(Director)

Co-investorsACADEMY INVESTORAIN VenturesFreshTracks CapitalScout VenturesScout VenturesVermont Center for Emerging Technologies (VCET)

Science Corporationscience.xyz

Science Corporation develops brain-computer interface and neural engineering technology to restore vision, cognition, and mobility to patients with debilitating conditions.

AI & Machine LearningBiotechDeep TechDigital HealthMedical DevicesAlameda, US

Max Hodak(Chief Executive Officer)

Co-investorsage1Artis VenturesAvalanche VCBeyond CapitalConversion CapitalDuke Capital Partners+8 more

Synchronsynchron.comin𝕏May 2021

Synchron develops brain-computer interface technology delivered via catheter to restore or improve motor and cognitive function in people with impairment or decline.

BiotechDeep TechMedical DevicesCampbell, US

Thomas James Oxley(Executive Officer, Director)Nicholas Opie(Director)inThomas Oxley(Founder)in

BoardRahul Sharma(Director)Alex Morgan(Director)inMartin Dieck(Director)

PartnerAriane Tom· led

Co-investorsARCH Venture PartnersForepont Capital PartnersID8 InvestmentsKhosla VenturesBezos ExpeditionsIn-Q-Tel+4 more

Therapeutic Platform for Protein Misfolding
Wearable Neurostimulation Device
Wireless Power Transfer Platform

Portfolio news

latest coverage across their companies

Frequently asked questions

How many investments has Kaleida Capital made?
Kaleida Capital has 16 tracked investments.
What sectors does Kaleida Capital focus on?
Kaleida Capital focuses on AI & Machine Learning, Biotech, Deep Tech, Digital Health, Healthtech, Medical Devices, Mental Health.
Where is Kaleida Capital located?
Kaleida Capital is headquartered in San Diego, US.
Who does Kaleida Capital co-invest with?
Kaleida Capital most often shares deals with Khosla Ventures, ARCH Venture Partners, Artis Ventures, among 36 tracked co-investors.

From the blog

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Kaleida Capital frames neurotechnology broadly as infrastructure at the intersection of neural data, AI, and cognition rather than only medical devices, arguing that neural data and brain-inspired AI represent critical assets for next-generation intelligent systems with near-term applications in medicine and eventually broader human-computer interaction. AI summary

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