Main Sequence Ventures — Full Portfolio

Morse Micro designs Wi-Fi HaLow (IEEE 802.11ah) system-on-chip semiconductors that provide long-range, low-power sub-1 GHz wireless connectivity for IoT devices such as security cameras, dongles, and access points.

HardwareIoTSemiconductorsSydney, AU

Andrew Terry(Co-founder & CTO)inMichael De Nil(Co-founder & CEO)inJoe Bedewi(Chief Financial Officer)in

Co-investorsBlackbird VenturesRight Click CapitalSpringCapital InvestmentStoic VCVirescent VenturesStartmate+1 more

Advanced Navigation develops navigation and positioning systems using inertial, photonic, and quantum sensing technologies for autonomous systems across defense, space, climate science, and commercial applications.

AI & Machine LearningDeep TechDefense TechIoTRoboticsSpace Tech

Chris Shaw(Founder & CEO)in

Co-investorsAirTree VenturesAlpha Intelligence CapitalBrick Mortar VenturesIn-Q-TelKohlberg Kravis RobertsOIF Ventures+2 more

Australian electricity retailer passing through wholesale prices with smart-home integration for cheaper, greener power.

Co-investorsBlack Sheep CapitalMighty PartnersTripple

Arkeus builds AI-powered sensing systems that combine advanced sensors with onboard AI to give autonomous platforms real-time situational awareness at the edge.

AI & Machine LearningDeep TechDefense TechHardwareRobotics

Co-investorsFolklore VenturesSalus VenturesQIC VenturesR+ VC

Arlula builds infrastructure for Earth Observation, providing automated, secure systems that move satellite data through organizations at scale.

Data & InfrastructureSaaSSpace Tech

Co-investorsBlack Nova VCCroc PitchLockheed Martin Ventures

Avarni provides AI-powered software that helps finance, compliance and sustainability teams measure supply-chain carbon emissions and meet sustainability reporting regulations.

CleantechClimate TechEnterprise SoftwareSaaSAustralia, AU

Misha(Co-founder)inAnuj(Co-founder)in

Co-investorsAfterWork VenturesCommon Sense VenturesVulpes Ventures

Baraja manufactures LiDAR sensors using Spectrum-Scan technology for autonomous vehicles and self-driving applications.

AI & Machine LearningDeep TechHardwareMobility & Transportation

PartnerBill Bartee· led

Co-investorsBlackbird VenturesInterValley Ventures

Breaker is an app for discovering and listening to podcasts, with plans to offer exclusive premium audio content on a paid subscription basis to listeners and provide publishers with analytics and community engagement tools.

ConsumerMedia & EntertainmentSan Francisco, US

Leah Culver(Founder/CTO)in

Co-investorsBessemer Venture PartnersY CombinatorACE & CompanySE Ventures

Castlepoint provides AI-powered data governance solutions that help corporate clients manage cybersecurity risks and ensure secure information management across complex networks.

AI & Machine LearningCybersecurityData & InfrastructureEnterprise SoftwareGovTech

Rachael Greaves(Founder and CEO)

Co-investorsFlying Fox Ventures

Eden Brew develops food and supplementation products designed to deliver nutrition in natural forms that align with how the human body processes nutrients, with a focus on sustainable scaling and long-term health support.

BiotechDeep TechFoodTechHealthtechImpact & Social Good

Jim Fader(CEO)in

Co-investorsBreakthrough VictoriaDigitalis Ventures

ElectraLith develops electrochemical and material-science technologies for lithium production and battery recycling in the renewable energy and mining sectors.

CleantechDeep TechEnergyNew Materials

Charlie McGill(CEO)SJ Oosthuizen(CTO)in

Co-investorsBreakthrough VictoriaVX VenturesFathom

Emesent builds AI-powered mobile LiDAR scanners and autonomous mapping technology, including the GX1 handheld scanner and the Hovermap drone platform, that use SLAM to map GPS-denied and hard-to-reach environments.

AI & Machine LearningHardwareRobotics

Co-investorsArchangel VenturesPerennial Partners

Next-generation clean energy storage to power communities, remote industries, and off-grid infrastructure.

Co-investors77 PartnersMelt Ventures

Fivecast provides AI-enabled open-source intelligence software that collects and analyzes online data to surface security risks and actionable insights.

AI & Machine LearningCybersecurityDefense TechGovTechAustralia, AU

Dr Brenton Cooper(CEO & Director, Co-founder)Duane Rivett(VP Strategic Growth, Co-founder)Ross Buglak(VP Product Development, Co-founder)David Blockow(VP Engineering, Co-founder)

Co-investorsArtesianSouth Australian Venture Capital FundTen Eleven

A launch services company that develops vehicles and satellite systems for space missions.

Deep TechDefense TechHardwareSpace TechGold Coast, AU

James Gilmour(Co-Founder, Head of Launch Site Operations)Adam Gilmour(Co-Founder, Chief Executive Officer)

Gilmour Space is an Australian space technology company developing an integrated launch capability, including its Eris launch vehicles, ElaraSat satellite platform, and a licensed spaceport in North Queensland.

Deep TechDefense TechMobility & TransportationSpace TechGold Coast, AU

Adam Gilmour(Founder)inJames GilmourinMichelle Gilmourin

Co-investors500 GlobalBlackbird VenturesFine Structures Ventures

Inventia Life Science provides RASTRUM Workflow Paths, tools for generating reproducible 3D cell models for research and drug discovery.

AI & Machine LearningBiotechDeep TechMedical Devices

Co-investorsTenmileVU Venture Partners

Kapiche is an AI-powered conversation intelligence platform that analyzes customer interactions across all channels to identify patterns, predict churn, and measure customer experience ROI.

AI & Machine LearningEnterprise SoftwareSaaS

RyanKris

Co-investorsFlying Fox VenturesMoxxie VenturesSydney AngelsTransition Level Investments

Kasada provides a bot defense and fraud prevention platform that detects and blocks automated bot attacks, account takeover, scraping, and human fraud without relying on CAPTCHAs.

CybersecurityEnterprise SoftwareSaaS

Sam Crowther(Founder)

Co-investorsIn-Q-TelOIF VenturesOur Innovation FundTen ElevenReinventure Group

Levur engineers sustainable oils through microbial fermentation to replace unsustainable plant and animal oils in food and cosmetic products.

AgTechBiotechCleantechClimate TechFoodTech

Using microbes to draw down carbon into soils at scale.

Co-investorsAcre Venture PartnersArtesianHAWKTAILHorizons VenturesLOWERCARBONLowercarbon Capital+2 more

Lumachain provides software for real-time visibility and quality data analytics to optimize the management and quality of perishable goods for the food service industry.

Advanced ManufacturingAI & Machine LearningData & InfrastructureFoodTechSydney, AU

Jamila Gordon(Founder)in

Co-investorsBessemer Venture Partners

MGA Thermal develops thermal energy storage materials and systems based on patented Miscibility Gap Alloy technology for renewable energy applications.

CleantechClimate TechEnergyNew MaterialsNewcastle, AU

Alexander Post(Chief Technology Officer & Co-Founder)Erich Kisi(Executive Chair, Chief Scientist, & Co-Founder)

Co-investorsAlberts Impact VenturesClimate Venture Capital FundCP VenturesMelt Ventures

Millibeam develops PHASEBEAM, a low-cost 5G transceiver platform for FR1 applications in the 3.3–4.1 GHz band, supporting 2x2 MIMO configurations for handsets and fixed wireless access devices.

Deep TechHardwareSemiconductorsNot stated, AU

Co-investorsArchangel VenturesBreakthrough Victoria

Myriota provides satellite connectivity infrastructure for IoT devices, enabling partners to develop solutions across industries.

AgTechHardwareIoTSpace Tech

Dr David Haley(CTO & Co-Founder)

Co-investorsArtesianBoeing HorizonX VenturesIn-Q-TelInterValley VenturesRight Click CapitalSouth Australian Venture Capital Fund+1 more

Nourish Ingredients develops animal-free fats and lipids using precision fermentation, including Tastilux (a fungal-fermentation phospholipid for meaty flavour) and Creamilux (a short-chain lipid emulsifier for dairy mouthfeel).

BiotechFoodTechNew Materials

Co-investorsHorizons Ventures

Number8 develops solutions to increase productivity and reduce emissions in grass-fed cattle operations and their retail supply chain.

AgTechBiotechClimate TechFoodTechImpact & Social GoodAustralia, AU

Tom Williams(Co-founder)Alex Carpenter(Co-founder)

Co-investorsBreakthrough VictoriaIcehouse VenturesPossible VenturesThe March Group

Pending AI develops a drug discovery and development platform using quantum mechanics and artificial intelligence to enable pharmaceutical companies to develop medicines for any disease.

AI & Machine LearningBiotechDeep TechBoston, US

Pennylane is a financial and accounting management platform.

Enterprise SoftwareFintechSaaSParis, FR

Arthur Waller(Founder)inEdouard MascréFélix BlossierinQuentin de Metz(Founder)Tancrède Besnard(Founder)Thierry Déo

Co-investorsCapitalGKima VenturesSequoia CapitalTCVAngel InvestAtomico+16 more

Plotlogic develops OreSense®, a sensing and AI platform that provides real-time, quantitative mineral data to help mining operators make extraction decisions.

AI & Machine LearningCleantechDeep TechHardwareRed Hill, AU

Andrew Job(Executive Officer, Director)inSteve Lennard(CEO)in

BoardSaman Farid(Director)Grant Allen(Director)Samantha Smith-Eppsteiner(Director)inAlireza Tahmasebzadeh(Director)

Co-investorsCerity Partners VenturesDCVC (Data Collective)SE VenturesGalvanize Climate SolutionsInnovation Endeavors

Practera is an AI-driven experiential learning company that connects university students with real industry projects and work experiences through a combination of technology platform and managed program delivery.

AI & Machine LearningB2B MarketplacesEdTechFuture of WorkSaaSSan Francisco, US

Beau Leese(Co-Founder and Co-CEO)inWes Sonnenreich(Co-Founder and Co-CEO)inSuzy Watson(Co-Founder and CFO)in

Presien develops plug-and-play computer vision and on-machine AI ("physical AI") solutions that heavy industry OEMs and technology providers integrate into machines to enable real-time operational insights.

AI & Machine LearningConstruction TechRoboticsSydney, AU

Co-investorsFlying Fox VenturesIn-Q-Tel

PartnerBill Bartee· led

Q-CTRL builds AI-powered control software for quantum computing systems, enabling manipulation and optimization of quantum computers without destroying quantum states.

AI & Machine LearningDeep TechQuantum Computing

Michael J. Biercuk(Founder & Chief Executive Officer)

PartnerBill Bartee· led

Co-investorsAlpha EdisonDCVC (Data Collective)Grit VenturesIn-Q-TelSalus VenturesSierra Ventures+10 more

Quantum Brilliance develops integrated quantum microchips based on diamond nitrogen-vacancy centers for sensing and computing applications.

Deep TechHardwareQuantum ComputingSemiconductorsStuttgart, DE

Marcus Doherty(Chief Technology Officer)Mark Luo(Chief Executive Officer)

Co-investorsBreakthrough VictoriaCP VenturesInterValley VenturesInvestible Climate Tech FundR&D Tax IncentiveRampersand

QuintessenceLabs provides post-quantum cryptography tools and quantum key distribution solutions to protect data encryption against threats from quantum computers.

CybersecurityEnterprise SoftwareQuantum ComputingCanberra, AU

Thomas Symul(Founder)

Co-investorsIn-Q-TelInterValley Ventures

RapidAIM develops IoT sensor hardware and mobile software for real-time pest detection and monitoring in orchards and farms.

AgTechIoTSaaS

Co-investorsAlberts Impact VenturesTenacious Ventures

Regrow provides software and services to help farmers and agricultural businesses adopt regenerative practices that reduce land-based emissions.

AgTechAI & Machine LearningClimate TechImpact & Social Good

Anastasia Volkova(CEO and Co-Founder)Anastasia Volkova, PhD(Founder)in

Co-investorsArtesianHAWKTAILRethink ImpactSE VenturesSpace CapitalTenacious Ventures+1 more

Co-investorsBreakthrough VictoriaDCVC (Data Collective)Fourward VenturesGreycroftHitachi VenturesTitanium Ventures+1 more

Skykraft provides air traffic management services delivered via satellite, including voice and data communications, surveillance, and positioning services for aviation over remote and oceanic regions.

Deep TechHardwareIoTSpace TechCanberra, AU

Solar technology replacing silver with copper to improve efficiency and reduce costs.

Co-investorsVirescent Ventures

Swoop operates global drone transport networks and aircraft to provide seamless aerial access in remote and inaccessible areas, with a focus on reducing carbon emissions and enabling delivery services.

HardwareLogistics & Supply ChainMobility & Transportation

Co-investorsFolklore VenturesIn-Q-TelRight Click CapitalArtesianGiant Leap

Terria develops open-source geospatial mapping and visualization technology, enabling government agencies, organizations, and the public to access, visualize, and analyze geographic data at scale.

AgTechAI & Machine LearningData & InfrastructureDeep TechGovTechPropTechSaaSMelbourne, AU

Ana Belgun(Co-founder / Chief Executive Officer)Amber Standley(Co-founder / Chief Experience Officer)in

Trellis Data provides an AI platform that ingests data from multiple sources, supports various AI model types (generative, speech, vision), and chains models together to solve complex workflows.

AI & Machine LearningData & InfrastructureDefense TechEnterprise SoftwareGovTech

Uluu develops plastic alternatives made from sustainable materials as a replacement for fossil fuel-based plastics, addressing plastic pollution at its source.

Circular EconomyCleantechNew Materials

Michael Kingsbury(Co-founder)Julia Reisser(Founder)in

Co-investorsAlberts Impact VenturesBurda Principal InvestmentsStartmatePossible VenturesTrinity Ventures

Plant-based meat that's good for you and for the planet

Surry Hills

Gareth William Sprainger(Chief Financial Officer)Chris Shi Chai Liu(Director)Philip David Morle(Director)Michael John Buchanan(Director)John James Cowin(Director)

BoardHendrik Van Asbroeck(Director)

Co-investorsAstanor Ventures

Xefco develops advanced materials and manufacturing solutions for the textile industry, with a focus on sustainable dyeing and finishing technologies.

Advanced ManufacturingCleantechNew MaterialsGeelong, AU

Co-investorsBreakthrough VictoriaPacific ChannelVirescent Ventures