Main Sequence Ventures — Full Portfolio

Morse Micro designs Wi-Fi HaLow (IEEE 802.11ah) system-on-chip semiconductors that provide long-range, low-power sub-1 GHz wireless connectivity for IoT devices such as security cameras, dongles, and access points.

HardwareIoTSemiconductorsSydney, AU

ATAndrew Terry(Founder)inMDMichael De Nil(Founder)inJBJoe Bedewi(Chief Financial Officer)in

Co-investorsBLBlackbird VenturesRIRight Click CapitalSPSpringCapital InvestmentSTStoic VCUNUniSeed Pty Ltd.VIVirescent Ventures+2 more

Advanced Navigation develops navigation and positioning systems using inertial, photonic, and quantum sensing technologies for autonomous systems across defense, space, climate science, and commercial applications.

AI & Machine LearningDeep TechDefense TechIoTRoboticsSpace Tech

CSChris Shaw(Founder)inChris(Founder)Xavier Orr(Founder)

Co-investorsAIAirTree VenturesALAlpha Intelligence CapitalBRBrick Mortar VenturesDYDysruptekINIn-Q-TelKOKohlberg Kravis Roberts+3 more

Amber gives Australian households direct access to wholesale electricity pricing so they can shift usage to cheaper, greener times and automatically export stored battery and EV energy for higher earnings.

CleantechClimate TechConsumerEnergy

CTChris Thompson(Founder)inDADan Adams(Founder)inJBJohn Bartonin

Co-investorsALAlberts Impact VenturesBLBlack Sheep CapitalBRBreakthrough VictoriaETETF PartnersGIGiant LeapIMImpact Ventures Management Pty Ltd+6 more

Andromeda Robotics builds empathetic companion robots designed to reduce loneliness and provide social interaction, developed in partnership with aged care and assisted living providers for their residents.

AI & Machine LearningHealthtechRoboticsWellness & FitnessSouth Melbourne, AU

Grace Brown(Founder)inYanqiu Chen(Executive Officer, Director)DGDaniel Gross(Founder)inNFNat Friedman(Founder)inTasnim Ahmed(Founder)

BoardDerek Gerrard(Director)

Co-investorsARArtesianBLBlackbird VenturesFOForerunner VenturesGAGalileo VenturesNANavis Capital PartnersPUPurpose Ventures+5 more

Arkeus builds AI-powered sensing systems that combine advanced sensors with onboard AI to give autonomous platforms real-time situational awareness at the edge.

AI & Machine LearningDeep TechDefense TechHardwareRobotics

JNJonathan Nebauer(Founder)in

Co-investorsBEBeaten Zone Venture PartnersFOFolklore VenturesQIQIC VenturesSASalus VenturesR+R+ VC

Arlula builds infrastructure for Earth Observation, providing automated, secure systems that move satellite data through organizations at scale.

Data & InfrastructureSaaSSpace Tech

SCSebastian Chaoui(Founder)in

Co-investorsBLBlack Nova VCCRCroc PitchLOLockheed Martin VenturesSTStartmate

Avarni provides AI-powered software that helps finance, compliance and sustainability teams measure supply-chain carbon emissions and meet sustainability reporting regulations.

CleantechClimate TechEnterprise SoftwareSaaSAustralia, AU

MMisha(Co-founder)inAAnuj(Co-founder)in

Co-investorsAFAfterWork VenturesCOCommon Sense VenturesSPSprint VenturesVUVulpes Ventures

Baraja manufactures LiDAR sensors using Spectrum-Scan technology for autonomous vehicles and self-driving applications.

AI & Machine LearningDeep TechHardwareMobility & Transportation

Cibby Pulikkaseril(Founder)Federico Collarte(Founder)

PartnerBBBill Bartee· led

Co-investorsBLBlackbird VenturesINInterValley VenturesSESequoia Capital

Breaker is a mobile application for listening to and discovering podcasts, with plans to distribute premium podcasts through exclusive deals under a paid subscription.

ConsumerMedia & EntertainmentSocialSan Francisco, US

LCLeah Culver(CTO)inErik Berlin(CEO)

Co-investorsBEBessemer Venture PartnersSCScript CapitalY Y CombinatorACACE & CompanyARArena VenturesBEBetaworks Ventures Management, Llc+7 more

Castlepoint provides AI-powered data governance solutions that help corporate clients manage cybersecurity risks and ensure secure information management across complex networks.

AI & Machine LearningCybersecurityData & InfrastructureEnterprise SoftwareGovTech

RGRachael Greaves(Founder and CEO)in

Co-investorsFLFlying Fox Ventures

Michele Stansfield(Founder)

Co-investorsSOSOSV

Deteqt develops a chip-scale quantum sensing platform using diamond-on-chip technology to produce vector magnetometers on silicon wafers.

Deep TechHardwareQuantum Computing

Co-investorsBEBeaten Zone Venture PartnersUNUniSeed Pty Ltd.

Deteqt develops a chip-scale quantum sensing platform using diamond-on-chip technology to produce vector magnetometers on silicon wafers.

Deep TechHardwareQuantum Computing

Jim Rabeau(Founder)Omid Kavehei(Founder)

Co-investorsBEBeaten Zone Venture Partners

Diraq develops quantum computers based on modified silicon transistors, aiming for utility-scale quantum processing units the size of a single data-center rack.

Deep TechHardwareQuantum Computing

ADAndrew Dzurak(Founder)in

Co-investorsDEDefence TrailblazerIMimec.xpandINIn-Q-TelQBQbeat VenturesQUQuantonationUNUniSeed Pty Ltd.+1 more

Eden Brew develops food and supplementation products designed to deliver nutrition in natural forms that align with how the human body processes nutrients, with a focus on sustainable scaling and long-term health support.

BiotechDeep TechFoodTechHealthtechImpact & Social Good

JFJim Fader(Founder)in

Co-investorsBRBreakthrough VictoriaININP CapitalDIDigitalis VenturesPOPossible VenturesRARadar Ventures

ElectraLith develops electrochemical and material-science technologies for lithium production and battery recycling in the renewable energy and mining sectors.

CleantechDeep TechEnergyNew Materials

CMCharlie McGill(CEO)inSOSJ Oosthuizen(CTO)in

Co-investorsBRBreakthrough VictoriaINIn-Q-TelVXVX VenturesFAFathom

Emesent builds AI-powered mobile LiDAR scanners and autonomous mapping technology, including the GX1 handheld scanner and the Hovermap drone platform, that use SLAM to map GPS-denied and hard-to-reach environments.

AI & Machine LearningHardwareRobotics

Co-investorsARArchangel VenturesINIn-Q-TelPEPerennial Partners

Endua designs and manufactures PEM electrolyser technology for on-site hydrogen generation and long-duration renewable energy storage.

Advanced ManufacturingCleantechEnergyHardwareAustralia, AU

Co-investors7777 PartnersMEMelt VenturesQIQIC Ventures

Every.io is a financial technology company that enables businesses to invest in U.S.

Enterprise SoftwareFintechFuture of WorkSaaSSan Francisco, US

RBRajeev Behera(CEO & Co-Founder)inBPBarry Peterson(CTO & Co-Founder)inMichael Edwards(Head of Sales)Yasmin Acevedo(Recruiter)

Co-investorsRERedpoint VenturesY Y CombinatorFOFormus CapitalMAMaiora Rebel VenturesOKOkta VenturesOLOlive Tree Capital+16 more

Fivecast provides AI-enabled open-source intelligence software that collects and analyzes online data to surface security risks and actionable insights.

AI & Machine LearningCybersecurityDefense TechGovTechAustralia, AU

DBDr Brenton Cooper(CEO and Co-Founder)inDRDuane Rivett(VP Strategic Growth, Co-founder)inRBRoss Buglak(VP Product Development, Co-founder)DBDavid Blockow(VP Engineering, Co-founder)in

Co-investorsARArtesianSOSouth Australian Venture Capital FundTETen Eleven

A launch services company that develops vehicles and satellite systems for space missions.

Deep TechDefense TechHardwareMobility & TransportationSpace TechGold Coast, AU

Michelle GilmourinJames Gilmour(Founder)inAGAdam Gilmour(Founder)

Co-investors50500 GlobalBLBlackbird VenturesFIFine Structures VenturesQIQIC Ventures

Indee Labs develops a non-viral intracellular delivery system based on microfluidic vortex shedding (µVS) to deliver nucleic acids, proteins, and gene editing complexes into patient and donor T cells.

BiotechDeep TechHealthtechMedical DevicesSan Francisco, US

RPRyan Pawell(CEO)inAdrian Lievano(Bioengineer)Amy Twite,Eva Welles(HR Consultant)

Co-investorsJUJude GomilaPIPioneerSOSOSVY Y CombinatorBRBroadOak Capital PartnersFOFounders Fund

Inventia Life Science provides RASTRUM Workflow Paths, tools for generating reproducible 3D cell models for research and drug discovery.

AI & Machine LearningBiotechDeep TechMedical Devices

Co-investorsAIAirTree VenturesINIn-Q-TelTETenmileTHThe Innovation SpaceVUVU Venture PartnersBLBlackbird Ventures+1 more

JDoodle is a browser-based coding platform offering an online IDE that runs 114 languages, frameworks, and databases with no installation, plus an AI coding companion.

Cloud ComputingDeveloper ToolsEdTech

Co-investorsUNUNSW Founders 10x

Kapiche is an AI-powered conversation intelligence platform that analyzes customer interactions across all channels to identify patterns, predict churn, and measure customer experience ROI.

AI & Machine LearningEnterprise SoftwareSaaS

RyanKris

Co-investorsFLFlying Fox VenturesMOMoxxie VenturesSYSydney AngelsTRTransition Level InvestmentsBLBlackbird Ventures

Kasada builds bot mitigation and defense technology that protects businesses from automated attacks and malicious bots by focusing on attacker behavior and motivations.

CybersecurityEnterprise SoftwareSaaSSydney, AU

SCSam Crowther(Founder)in

Co-investorsINIn-Q-TelOIOIF VenturesOUOur Innovation FundREReinventure GroupTETen ElevenEQEQT

Levur engineers sustainable oils through microbial fermentation to replace unsustainable plant and animal oils in food and cosmetic products.

AgTechBiotechCleantechClimate TechFoodTech

TCTom Collier(Founder)in

Co-investorsGRGrainCorp VenturesSPSparkLabs Cultiv8

Using microbes to draw down carbon into soils at scale.

Frank Oly(Founder)Guy Hudson(Founder)Guy Webb(Chief Agronomy Officer & Co-founder)Mick Wettenhall(Founder)Tegan Nock(Founder)Rob Hranac(Chief Executive Officer (CEO))

Co-investorsACAcre Venture PartnersARArtesianHAHAWKTAILHOHorizons VenturesLOLowercarbon CapitalNSNSW Clean Technology Innovation Grants+4 more

Lumachain provides software for real-time visibility and quality data analytics to optimize the management and quality of perishable goods for the food service industry.

Advanced ManufacturingAI & Machine LearningData & InfrastructureFoodTechSydney, AU

JGJamila Gordon(Founder)in

Co-investorsBEBessemer Venture PartnersNENextwave [X] Partners

MGA Thermal develops thermal energy storage materials and systems based on patented Miscibility Gap Alloy technology for renewable energy applications.

CleantechClimate TechEnergyNew MaterialsNewcastle, AU

APAlexander Post(Chief Technology Officer & Co-Founder)inEKErich Kisi(Executive Chair, Chief Scientist, & Co-Founder)in

Co-investorsALAlberts Impact VenturesCLClimate Venture Capital FundCPCP VenturesMEMelt Ventures

Millibeam develops PHASEBEAM, a low-cost 5G transceiver platform for FR1 applications in the 3.3–4.1 GHz band, supporting 2x2 MIMO configurations for handsets and fixed wireless access devices.

Deep TechHardwareSemiconductorsNot stated, AU

Co-investorsARArchangel VenturesBRBreakthrough VictoriaARArchangel

Myriota provides satellite connectivity infrastructure for IoT devices, enabling partners to develop solutions across industries.

AgTechHardwareIoTSpace TechAdelaide, AU

DDDr David Haley(CTO & Co-Founder)Ben Cade(CEO)

Co-investorsARArtesianBOBoeing HorizonX VenturesINIn-Q-TelINInterValley VenturesRIRight Click CapitalSOSouth Australian Venture Capital Fund+4 more

Nourish Ingredients develops animal-free fats and lipids using precision fermentation, including Tastilux (a fungal-fermentation phospholipid for meaty flavour) and Creamilux (a short-chain lipid emulsifier for dairy mouthfeel).

BiotechFoodTechNew Materials

Co-investorsHOHorizons Ventures

Nourish Ingredients uses precision fermentation and lipid biotechnology to make animal-free fats and flavor ingredients, including Tastilux (a meaty phospholipid flavor) and Creamilux (a dairy emulsifier), for use in alternative meat and plant-based or hybrid dairy products.

BiotechFoodTech

JPJames Petrie(Founder)inAnna El Tahchy(CTO & Founder Director)inBen Leita(Founder)James Petrie Ben Leita(Founder)

Co-investorsRARadar Ventures

Number 8 Bio develops feed additives for livestock producers that improve nutrient absorption and feed efficiency while reducing methane emissions.

AgTechBiotechClimate Tech

Alex Carpenter(Founder)Tom Williams(Founder)

Number8 develops solutions to increase productivity and reduce emissions in grass-fed cattle operations and their retail supply chain.

AgTechBiotechClimate TechFoodTechImpact & Social GoodAustralia, AU

Tom Williams(Co-founder)Alex Carpenter(Co-founder)in

Co-investorsBRBreakthrough VictoriaICIcehouse VenturesPOPossible VenturesTHThe March Group

Pending AI develops a drug discovery and development platform using quantum mechanics and artificial intelligence to enable pharmaceutical companies to develop medicines for any disease.

AI & Machine LearningBiotechDeep TechBoston, US

Mark P. Waller(Founder)in

Co-investorsBLBlackbird Ventures

Pennylane is a financial and accounting management platform.

Enterprise SoftwareFintechSaaSParis, FR

AWArthur Waller(Founder)inEMEdouard Mascré(Founder)inFBFélix Blossier(Founder)inQuentin de Metz(Founder)inTBTancrède Besnard(Founder)inThierry Déo

Co-investorsCACapitalGDIDiscovery Ventures III Gmb H & Co. KGKIKima VenturesPAPartech VenturesSESequoia CapitalTCTCV+19 more

Plotlogic develops OreSense®, a sensing and AI platform that provides real-time, quantitative mineral data to help mining operators make extraction decisions.

AI & Machine LearningCleantechDeep TechHardwareRed Hill, AU

AJAndrew Job(Founder)inSteve Lennard(CEO)in

BoardSaman Farid(Director)Grant Allen(Director)SSSamantha Smith-Eppsteiner(Director)inAlireza Tahmasebzadeh(Director)

Co-investorsCECerity Partners VenturesDCDCVC (Data Collective)SESE VenturesGAGalvanize Climate SolutionsINInnovation Endeavors

Practera is an AI-driven experiential learning company that connects university students with real industry projects and work experiences through a combination of technology platform and managed program delivery.

AI & Machine LearningB2B MarketplacesEdTechFuture of WorkSaaSSan Francisco, US

BLBeau Leese(Co-Founder and Co-CEO)inWSWes Sonnenreich(Co-Founder and Co-CEO)inSWSuzy Watson(Co-Founder and CFO)in

Presien develops plug-and-play computer vision and on-machine AI ("physical AI") solutions that heavy industry OEMs and technology providers integrate into machines to enable real-time operational insights.

AI & Machine LearningConstruction TechRoboticsSydney, AU

KMKieran MacKenzie(Founder)in

Co-investorsFLFlying Fox VenturesINIn-Q-Tel

Prospection turns longitudinal patient and real-world claims data into analytics that map the complete patient journey and predict likely next steps, using a proprietary transformer-based AI architecture.

AI & Machine LearningData & InfrastructureDigital Health

PartnerBBBill Bartee· led

Co-investorsGLGlitch CapitalBLBlackbird Ventures

Q-CTRL builds AI-powered control software for quantum computing systems, enabling manipulation and optimization of quantum computers without destroying quantum states.

AI & Machine LearningDeep TechQuantum Computing

MJMichael J. Biercuk(Founder)in

PartnerBBBill Bartee· led

Co-investors181802 VenturesALAlpha EdisonALAlumni VenturesDCDCVC (Data Collective)GRGrit VenturesINIn-Q-Tel+12 more

Quantum Brilliance develops integrated quantum microchips based on diamond nitrogen-vacancy centers for sensing and computing applications.

Deep TechHardwareQuantum ComputingSemiconductorsStuttgart, DE

MDMarcus Doherty(Founder)inMark Luo(Founder)inAndrew Horsley(Founder)

Co-investorsBRBreakthrough VictoriaCPCP VenturesINIn-Q-TelINInterValley VenturesINInvestible Climate Tech FundR&R&D Tax Incentive+6 more

QuintessenceLabs builds quantum cybersecurity products, including key and policy management, crypto-agility tooling, quantum key distribution, and quantum random number generation to help enterprises adopt post-quantum resistant encryption.

CybersecurityDeep TechEnterprise SoftwareQuantum ComputingCanberra, AU

TSThomas Symul(Founder)inAndreas BaumhofinMark CrowleyinVikram Sharma(Founder and CEO)

Co-investorsCHChevron Technology VenturesINIn-Q-TelINInterValley VenturesBLBlackbird Ventures

Rainstick develops weather-event and biotech-related technology, drawing on hardware and software engineering.

AgTechBiotechClimate TechDeep TechQueensland, AU

DLDarryl Lyons(Cofounder, Chief Rainmaker)inMBMic Black(Cofounder, Chief Thunderstorm Creator)in

Co-investorsBEBetter Bite VenturesSTStartmate Launch Club

RapidAIM develops IoT sensor hardware and mobile software for real-time pest detection and monitoring in orchards and farms.

AgTechIoTSaaS

Co-investorsALAlberts Impact VenturesTETenacious Ventures

Regrow provides software and services to help farmers and agricultural businesses adopt regenerative practices that reduce land-based emissions.

AgTechAI & Machine LearningClimate TechImpact & Social Good

AVAnastasia Volkova(Founder)inWilliam Salas(Founder)

Co-investorsAIAirTree VenturesARArtesianHAHAWKTAILRERethink ImpactSESE VenturesSPSpace Capital+4 more

AI-powered enzyme technology that breaks down hard-to-recycle plastics for infinite recycling.

Paul Riley(Founder)

Co-investorsBRBreakthrough VictoriaDCDCVC (Data Collective)FOFourward VenturesGRGreycroftHIHitachi VenturesININP Capital+5 more

Skykraft provides air traffic management services delivered via satellite, including voice and data communications, surveillance, and positioning services for aviation over remote and oceanic regions.

Deep TechHardwareIoTSpace TechCanberra, AU

Co-investorsDEDefence Trailblazer

SunDrive is a solar technology company developing methods to lower the cost of high-efficiency solar cells while improving their performance and sustainability by using more abundant materials.

CleantechDeep TechEnergySydney, AU

Co-investorsBLBlackbird VenturesVIVirescent Ventures

Swoop operates global drone transport networks and aircraft to provide seamless aerial access in remote and inaccessible areas, with a focus on reducing carbon emissions and enabling delivery services.

HardwareLogistics & Supply ChainMobility & TransportationSydney, US

Eric Peck(Founder)Josh Tepper(Founder)

Co-investorsFOFolklore VenturesGIGiant LeapINIn-Q-TelRIRight Click CapitalARArtesian

Terria develops open-source geospatial mapping and visualization technology, enabling government agencies, organizations, and the public to access, visualize, and analyze geographic data at scale.

AgTechAI & Machine LearningData & InfrastructureDeep TechGovTechPropTechSaaSMelbourne, AU

Ana Belgun(Co-founder / Chief Executive Officer)inASAmber Standley(Co-founder / Chief Experience Officer)in

Trellis Data provides an AI platform that ingests data from multiple sources, supports various AI model types (generative, speech, vision), and chains models together to solve complex workflows.

AI & Machine LearningData & InfrastructureDefense TechEnterprise SoftwareGovTech

MGMichael G.(Founder)in

Uluu develops plastic alternatives made from sustainable materials as a replacement for fossil fuel-based plastics, addressing plastic pollution at its source.

Circular EconomyCleantechNew Materials

MKMichael Kingsbury(Founder)inJRJulia Reisser(Founder)in

Co-investorsALAlberts Impact VenturesBUBurda Principal InvestmentsPOPossible VenturesSTStartmateTRTrinity Ventures

v2food makes plant-based meat alternatives sold through retail and food-service partners, and provides recipes for consumers cooking with its products.

ConsumerFoodTechSurry Hills

Gareth William Sprainger(Chief Financial Officer)

BoardChris Shi Chai Liu(Director)Philip David Morle(Director)HVHendrik Van Asbroeck(Director)inMichael John Buchanan(Director)John James Cowin(Director)

Co-investorsASAstanor VenturesBLBlue Horizon CorporationHOHorizons VenturesTETemasek

Xefco develops advanced materials and manufacturing solutions for the textile industry, with a focus on sustainable dyeing and finishing technologies.

Advanced ManufacturingCleantechNew MaterialsGeelong, AU

THTom Hussey(Founder)in

Co-investorsBRBreakthrough VictoriaPAPacific ChannelVIVirescent Ventures