Breakout Ventures — Full Portfolio

Twelve transforms CO2 into chemicals, fuels, and materials through carbon transformation technology.

Advanced ManufacturingCleantechClimate TechHealthtechNew MaterialsMoses Lake, US

NFNicholas Flanders(Founder)inECEtosha Cave(Founder)inKendra Kuhl(Founder)inACAndrew Cleeland(Executive Officer, Director)in

BoardMarc-Henri Galletti(Director)Nimesh Shah(Director)

Co-investorsDCDCVC (Data Collective)DODolby Family VenturesFIFifth WallADAdvantage Partners Inc.AEAera VCBRBreakout Labs+36 more

Cytovale develops microfluidic deformability cytometry technology for immune response diagnostics, with a focus on early detection and diagnosis in hospital settings.

BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US

ASAjay Shah(Founder)inHTHenry Tse(Co-founder & Chief Technology Officer)inDino DiCarlo(Director, Promoter)

BoardJFJack Fuchs(Director, Promoter)in

Board seatLindy Fishburne· per SEC Form D

Co-investorsALAlumni VenturesBABasecamp FundBLBlackhorn VenturesBRBreakout LabsDODolby Family VenturesEMEMV Capital+5 more

Aquaporo manufactures drinking water directly from atmospheric humidity using proprietary ALMA technology, offering residential units (Droplet) and industrial modular systems (Stream) for on-site water production.

CleantechHardwareAnaheim, US

Kyle E. Cordova(Founder)in

BoardKristopher H Gilman(Director)

Board seatLindy Fishburne· per SEC Form D

Co-investorsCECerberus VenturesCOCool Climate CollectiveE8E8 AngelsHUHumba Ventures

Checkerspot uses microalgae precision fermentation to produce specialized lipids and fats, including a bio-equivalent source of the sn-2 palmitate fat found in mother's milk, rare bioactive fatty acids, and tropical fat alternatives.

BiotechClimate TechFoodTechNew MaterialsAlameda, US

Scott Franklin(Executive Officer, Director)inCDCharles Dimmler(Executive Officer, Director)inJKJohn Krzywicki(CEO)inLWLayla Ward(CFO)inCLCasey Lippmeier(CTO)inLPLeon Parker(SVP, Molecular Biology)in

Board seatJMJulia Moore· per SEC Form D

Co-investorsBABaruch Future VenturesCACavallo VenturesVIViking GlobalBUBuilders VCKDKdT VenturesPLPlug and Play Ventures+3 more

STRM.BIO develops technology to deliver gene therapies, aiming to improve how these treatments reach patients.

BiotechDeep TechHealthtechLongevityMedical Devices

MLMichael Luther(CEO)in

Co-investorsASAscension VenturesBRBreakout LabsDEDelos CapitalNYNYBC VenturesBOBoehringer Ingelheim Venture FundKDKdT Ventures+1 more

A-Alpha Bio uses synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions for pharmaceutical discovery and development.

AI & Machine LearningBiotechDeep TechSeattle, US

DYDavid Younger, PhD(Chief Executive Officer & Co-Founder)Randolph Lopez, PhD(Chief Technology Officer & Co-Founder)DYDavid Younger(Founder)inRLRandolph Lopez(Founder)in

Co-investorsANAngel Collective Opportunity FundFAFarvatn VentureLULux CapitalMAMadrona Venture GroupBOBoom CapitalBOBoom Capital Ventures+1 more

Canaery develops a nose-computer interface that combines animal olfaction with neurotechnology and AI to detect substances and diagnose diseases.

AI & Machine LearningBiotechDeep TechHardwareMedical Devices

Gabriel(Chief Executive Officer)Peter(Chief Technology Officer)

BoardDmitry(Chief Science Advisor)

Co-investors1515th RockFLFlorida Opportunity FundGOGood News VenturesNYNYU Innovation Venture FundDODolby Family VenturesKDKdT Ventures

CellChorus develops a visual AI platform called TIMING that performs high-throughput dynamic analysis of single cells, measuring cell activation, killing, and movement over time for biopharmaceutical research.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesHouston, US

DMDan Meyer(Founder)inNVNavin Varadarajan(Founder)inLCLaurence Cooper(Co-founder & Board Chair)inRBRebecca Berdeaux(Chief Scientific Officer)in

Co-investorsHOHouston Angel NetworkTETexas HALO FundY Y CombinatorASAsymmetry Ventures

Constellation develops foundation models of human state aimed at understanding brains, bodies, and environments.

AI & Machine LearningDeep TechHealthtech

Co-investorsMAMaC Venture Capital

Copernic develops catalysts for zero-carbon ammonia and e-fuels that are cost-competitive and compatible with existing industrial infrastructure.

CleantechClimate TechDeep TechEnergyCambridge, US

Aruna Ramkrishnan(Founder)inJacob Ebenstein Grose(Executive Officer, Director)

BoardLFLindy Fishburne(Director)inMKMichael Kearney(Director)inMichael LoCascio(Director)

Co-investorsFUFuture VenturesINInnospark VenturesJUJuniperNENew Climate VenturesTHThe Engine Ventures

Ecovative grows whole-cut meat alternatives and leather-like materials from mycelium using its AirMycelium indoor cultivation platform, which integrates with existing mushroom farming infrastructure.

BiotechFoodTechNew MaterialsGreen Island, US

EBEben Bayer(Cofounder)inGMGavin McIntyre(Founder)in

BoardEvan Lodes(Director)Jerry Weinstein(Director)Charles Deull(Director)Jessica Harris(Director)

Co-investorsBRBreakout LabsCOCool Climate CollectiveSTStray Dog CapitalTRTrousdale VenturesAIAiiM PartnersFOFootPrint Coalition+2 more

En Plus One Bio develops synthesis and manufacturing technology for RNA therapeutics, focused on producing high-purity long RNA with higher cycle efficiencies and novel chemical modifications.

BiotechDeep TechWatertown, US

DADaniel Ahlstedt(Executive Officer, Director)inJRJonathan Rittichier(Founder)inDaniel Wiegand(Founder)George M. Church(Founder)

BoardPMPaxton Major(Director)inALAndrew Lee(Director)in

Co-investorsCOCoatue ManagementNONorthpond Ventures

Epana Bio develops therapies for autoimmune diseases by leveraging genomics and AI to identify and target cellular origins of disease, with a focus on precision medicine for patient populations.

AI & Machine LearningBiotechDigital Health

Co-investorsBRBreakout LabsHAHAWKTAILHUHummingbird VenturesOMOMX VenturesPOPoint Financial CapitalKDKdT Ventures+2 more

Fountain provides an applicant tracking system designed specifically for hiring hourly workers at scale.

AI & Machine LearningEnterprise SoftwareHR TechMarketplacesSaaSSan Francisco, US

KRKeith Ryu(Founder)inJeremy Cai(Founder)

Co-investorsB B Capital GroupB4B4 CapitalBLBling CapitalCOCommerce VenturesCRCrosslink CapitalDCDCM Ventures+26 more

General Sense develops detection technology that augments trained detection animals, aiming to identify molecular threats such as narcotics, crop diseases, human diseases, and bioweapons.

BiotechDeep TechDefense TechHardware

Co-investorsDODolby Family VenturesDRDraper AssociatesJUJuniperSOSOSV

Vitra Bio is a biotechnology company developing technology aimed at transforming fertility treatment.

BiotechFemTechHealthtech

Ivana Muncie-Vasic(Chief Executive Officer and Founder)inJLJohn Langowski(Chief Technology Officer)in

Co-investorsFOForeground CapitalNONorth South VenturesSPSpacecadet VenturesBOBoom Capital VenturesRERefactor Capital

Immusoft develops a cell therapy platform called Immune System Programming (ISP) that engineers a patient's B cells into plasma cells that produce therapeutic proteins after being infused back into the patient.

BiotechDeep TechHealthtechSeattle, US

MSMatthew Scholz(Founder)inSASean Ainsworth(Chief Executive Officer)inRSRobert Sikorski(Chief Medical Officer)RHRob Hayes(Chief Scientific Officer)inSMScott McIvor(Chief Development Officer)Eric Garcia(Executive Officer)in

Co-investorsBIBioRock VenturesBOBoston Harbor AngelsEQEQx FundINInvariantes FundMIMichigan Capital NetworkNYNYBC Ventures+6 more

A digital supply chain platform that connects smallholder farmers with buyers across India, using automated quality assessment and transaction tracking to bypass traditional intermediaries and increase farmer revenue.

Advanced ManufacturingAgTechGurugram, IN

AAAditya Agarwalla(Founder)inSKSanjay Kumar Agarwalla(Founder)in

Co-investorsY Y CombinatorAGAgrolimen VenturesBEBEENEXTFUFundersClubLYLynett Capital PartnersMIMistletoe+2 more

Modern Meadow develops animal-free, bio-fabricated leather alternatives using synthetic biology and material science for the fashion, interiors, and automotive industries.

BiotechCircular EconomyNew MaterialsPine Brook, US

GFGabor Forgacs(Founder)inFrancoise Marga(Founder)inKaroly Jakab(Founder)inABAnna Bakst(Executive Officer, Director)inRex Liu(Executive Officer)DWDavid Williamson(CEO)in

Co-investorsARArtis VenturesASAstanor VenturesBRBreakout LabsCOCollaborative FundHOHorizons VenturesINInventus Capital Partners+7 more

Noetik builds AI models to identify cancer patients most likely to respond to treatments and to discover new oncology drug targets.

AI & Machine LearningBiotechHealthtechSouth San Francisco, US

Jacob Rinaldi(Founder)inRonald Alfa(Executive Officer, Director, Promoter)RARon Alfa, MD, PhD(Co-Founder, CEO)inRon Alfa(Founder)Ron Alfa Jacob Rinaldi(Founder)

BoardJHJames Hardiman(Director)in

Co-investors1111.2 CapitalBRBreakout LabsCACatalio Capital Management, LPEPEPIC VENTURESINIntermountain HealthLILinearis Ventures+6 more

Quince Therapeutics is a clinical-stage biopharmaceutical company developing eDSP, an investigational therapy studied in a Phase 3 clinical trial (NEAT) for patients with Ataxia-Telangiectasia (A-T).

BiotechHealthtechWest Lafayette, US

Philip S. Low, Ph.D.(Executive Officer, Director)David Lamond(Director)Daniel Hasler(Director)Dirk Thye, M.D.(Executive Officer, Director)William J. Rutter(Director)Alex Andrianopoulos(Director)

Co-investorsELElevate VenturesPFPfizer Venture Investments

Parallel Bio develops human immune organoids and computational tools to predict drug efficacy across diverse patient populations, replacing animal testing in drug discovery.

AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US

RDRobert DiFazio(Founder)inJHJuliana Hilliard(Founder)in

Co-investorsAIAIX VenturesHUHumba VenturesIMImmeasurableJUJulian CapitalMEMetaplanetSPSpacecadet Ventures+19 more

Passkey operates Locksmith, a computational platform that uses human genetics, biology, and pharmacology to identify synergistic drug combinations from approved and late-stage drugs, allowing existing assets to be repurposed for new indications.

AI & Machine LearningBiotechDeep Tech

Co-investorsBIBison VenturesWIWireframe Ventures

Phantom Neuro develops a minimally invasive, subcutaneous muscle-computer interface that uses under-the-skin sensors and on-device AI to translate muscle signals into control commands for robotic devices.

AI & Machine LearningBiotechMedical DevicesRoboticsAustin, US

CGConnor Glass(Executive Officer, Director, Promoter)in

BoardDWD.A. Wallach(Director)inEMEdward Michael(Director)inRLRobert Lord(Director)in

Co-investorsCACapital FactoryCRCrosscourt VenturesDRDraper AssociatesLILionBirdTITime BioVenturesE1E1 Ventures

Technology identifying supply chain sources using the environmental microbiome.

Co-investorsDODolby Family VenturesGOGolden SeedsJ-J-VenturesWOWorking Capital FundAGAgFunderBLBlackhorn Ventures+4 more

Reach Industries builds a visual intelligence layer for science, combining AI, software, and hardware to support work in the life sciences.

AI & Machine LearningBiotechDeep TechRoboticsLondon, GB

CBChris Beck(Co-founder & CTO)inSASilas Adekunle(Co-founder & CEO)in

Co-investorsENEntrepreneur FirstLULunar VenturesPAPassion CapitalIDId4 Ventures LimitedSOSOSV

ShiraTronics is a medical device company developing an implantable device to treat chronic migraine disease.

BiotechHardwareHealthtechMedical DevicesBrooklyn Park, US

Robert Binney(Executive Officer, Director)

BoardJEJoyce Erony(Director)inZSZack Scott(Director)inBVBrad Vale(Director)inCTCasey Tansey(Director)MJMudit Jain(Executive Officer, Director)in

Co-investorsAMAmzak HealthAPAPERTURE Venture PartnersGLGlobal BioAccess FundNONorwest Venture PartnersOSOSF VenturesSESeroba Life Sciences+3 more

Surf Bio is a preclinical biopharmaceutical company developing its SnapShot technology, which uses a proprietary polymer to create ultra-high-concentration antibody and biologic formulations (600+ mg/mL, doses over 1,000 mg) for delivery via a standard autoinjector.

BiotechDeep TechHealthtechPalo Alto, US

Bryan Mazlish(Chief Executive Officer, co-founder)inJSJennifer Schneider, MD(Co-founder, President & Chief Medical Officer)in

Co-investorsPAPantera Capital

A biotech company developing novel biologics designed to target and eliminate the drivers of cancer recurrence and metastasis.

Biotech

Transfyr builds a sensor stack and multimodal AI models that record and analyze the physical execution of scientific experiments, capturing details that distinguish success from failure.

AI & Machine LearningBiotechDeep Tech

Co-investorsGEGeneral CatalystLULux CapitalMVMVP VenturesSVSV AngelUNUnderscore VC

ZymoChem develops bio-based materials using proprietary Carbon Conserving (C2) microbes that convert renewable feedstocks into high-value materials with increased yields.

BiotechCircular EconomyClimate TechNew MaterialsSan Leandro, US

HCHarshal Chokhawala(Founder & CEO)in

Co-investorsACAccelr8BRBreakout LabsCACavallo VenturesDUDudley FundFRFreshTracks CapitalPRPrime Partners+7 more