Breakout Ventures — Full Portfolio

Twelve transforms CO2 into chemicals, fuels, and materials through carbon transformation technology.

Advanced ManufacturingCleantechClimate TechHealthtechNew MaterialsMoses Lake, US

Nicholas Flanders(Founder & CEO)inEtosha Cave(Founder)inKendra Kuhl(Founder)inAndrew Cleeland(Executive Officer, Director)

BoardMarc-Henri Galletti(Director)Nimesh Shah(Director)

Co-investorsDCVC (Data Collective)Dolby Family VenturesFifth WallAdvantage Partners Inc.Aera VCCantos Ventures+15 more

Cytovale develops microfluidic deformability cytometry technology for immune response diagnostics, with a focus on early detection and diagnosis in hospital settings.

BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US

Ajay Shah(Co-founder & CEO)inHenry Tse(Co-founder & Chief Technology Officer)inDino DiCarlo(Director, Promoter)

BoardJack Fuchs(Director, Promoter)in

Board seatLindy Fishburne· per SEC Form D

Co-investorsAlumni VenturesBasecamp FundBlackhorn VenturesBreakout LabsEMV CapitalIT-Farm Corporation+3 more

Aquaporo manufactures drinking water directly from atmospheric humidity using proprietary ALMA technology, offering residential units (Droplet) and industrial modular systems (Stream) for on-site water production.

CleantechHardwareAnaheim, US

Kyle E. Cordova(Founder)inKyle Ellis Cordova(Executive Officer, Director)

BoardKristopher H Gilman(Director)

Board seatLindy Fishburne· per SEC Form D

Co-investorsCool Climate CollectiveHumba VenturesCerberus Ventures

Checkerspot uses microalgae precision fermentation to produce specialized lipids and fats, including a bio-equivalent source of the sn-2 palmitate fat found in mother's milk, rare bioactive fatty acids, and tropical fat alternatives.

BiotechClimate TechFoodTechNew MaterialsAlameda, US

Scott Franklin(Executive Officer, Director)Charles Dimmler(Executive Officer, Director)John Krzywicki(CEO)Layla Ward(CFO)Casey Lippmeier(CTO)Leon Parker(SVP, Molecular Biology)

Board seatJulia (Thies) Moore· per SEC Form D

Co-investorsBaruch Future VenturesCavallo VenturesBuilders VCKdT VenturesRefactor Capital

Media, US

Peter Ledochowitsch(Executive Officer, Director)

Board seatLindy Fishburne· per SEC Form D · $3.5M raise · filed Jan 2022

Palo Alto, US

Bryan Mazlish(Executive Officer, Director)Jennifer Schneider(Executive Officer, Director)Ben Askew(Director)

Board seatLindy Fishburne· per SEC Form D · $16.3M raise · filed Apr 2022

STRM.BIO develops a gene therapy delivery platform based on megakaryocyte-derived extracellular vesicles (STRM MVs) that target and deliver genetic cargoes preferentially to bone marrow and hematopoietic stem cells.

BiotechDeep TechMedical Devices

Co-investorsAscension VenturesBreakout LabsDelos CapitalNYBC VenturesKdT Ventures

A-Alpha Bio uses synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions for pharmaceutical discovery and development.

AI & Machine LearningBiotechDeep TechSeattle, US

David Younger, PhD(Chief Executive Officer & Co-Founder)Randolph Lopez, PhD(Chief Technology Officer & Co-Founder)David Younger(Executive Officer, Director, Promoter)inRandolph Lopez(Founder)in

Co-investorsAngel Collective Opportunity FundFarvatn VentureLux CapitalMadrona Venture GroupBoom Capital VenturesOS Fund

Canaery (now General Sense) is developing scent-detection technology aimed at extending capabilities beyond the limits of human olfactory perception.

Deep TechHardware

Co-investors15th RockGood News VenturesDolby Family VenturesKdT Ventures

CellChorus develops a visual AI platform called TIMING that performs high-throughput dynamic analysis of single cells, measuring cell activation, killing, and movement over time for biopharmaceutical research.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesHouston, US

Dan Meyer(Founder)inNavin Varadarajan(Founder)inLaurence Cooper(Co-founder & Board Chair)Rebecca Berdeaux(Chief Scientific Officer)

Co-investorsHouston Angel NetworkTexas HALO FundY Combinator

Constellation develops foundation models of human state aimed at understanding brains, bodies, and environments.

AI & Machine LearningDeep TechHealthtech

Co-investorsMaC Venture Capital

Copernic develops catalysts for zero-carbon ammonia and e-fuels that are cost-competitive and compatible with existing industrial infrastructure.

CleantechClimate TechDeep TechEnergyCambridge, US

Aruna Ramkrishnan(Founder)inJacob Ebenstein Grose(Executive Officer, Director)

BoardLindy Fishburne(Director)inMichael Kearney(Director)inMichael LoCascio(Director)

Co-investorsFuture VenturesInnospark VenturesJuniperNew Climate VenturesThe Engine Ventures

Ecovative grows whole-cut meat alternatives and other materials from mycelium using its AirMycelium indoor cultivation platform, which integrates with existing mushroom farming infrastructure.

BiotechFoodTechNew MaterialsGreen Island, US

Gavin McIntyre(Executive Officer, Director)Eben Bayer(Executive Officer, Director)

BoardEvan Lodes(Director)Jerry Weinstein(Director)Charles Deull(Director)Jessica Harris(Director)

Co-investorsBreakout LabsStray Dog CapitalAiiM PartnersFootPrint CoalitionStandard InvestmentsViking Global Investors

En Plus One Bio develops synthesis and manufacturing technology for RNA therapeutics, focused on producing high-purity long RNA with higher cycle efficiencies and novel chemical modifications.

BiotechDeep TechWatertown, US

Daniel Ahlstedt(Executive Officer, Director)Jonathan Rittichier(Founder)in

BoardPaxton Major(Director)inAndrew Lee(Director)inSteven Kasok(Director)

Co-investorsCoatue ManagementNorthpond Ventures

Epana Bio develops therapies for autoimmune diseases by leveraging genomics and AI to identify and target cellular origins of disease, with a focus on precision medicine for patient populations.

AI & Machine LearningBiotechDigital Health

Co-investorsBreakout LabsHAWKTAILHummingbird VenturesOMX VenturesKdT VenturesRefactor Capital

General Sense provides multi-threat detection technology that identifies explosives, narcotics, and emerging chemical threats simultaneously without specialized teams.

Deep TechDefense TechHardware

Co-investorsDraper AssociatesJuniper

Vitra develops reproductive therapies that mature eggs outside the body in a controlled environment, aiming to reduce or eliminate the hormone injections required in conventional IVF.

BiotechFemTechHealthtech

Ivana Muncie-Vasic(Founder)in

Co-investorsForeground CapitalNorth South VenturesSpacecadet VenturesBoom Capital VenturesRefactor Capital

Immusoft develops a cell therapy platform called Immune System Programming (ISP) that engineers a patient's B cells into plasma cells that produce therapeutic proteins after being infused back into the patient.

BiotechDeep TechHealthtechSeattle, US

Matthew Scholz(Founder)Sean Ainsworth(Chief Executive Officer)Robert Sikorski(Chief Medical Officer)Rob Hayes(Chief Scientific Officer)Scott McIvor(Chief Development Officer)Richard Chin, M.D.(Director)

Co-investorsBioRock VenturesBoston Harbor AngelsEQx FundInvariantes FundMichigan Capital NetworkNYBC Ventures+1 more

Modern Meadow develops animal-free, bio-fabricated leather alternatives using synthetic biology and material science for the fashion, interiors, and automotive industries.

BiotechCircular EconomyNew MaterialsPine Brook, US

Gabor Forgacs(Director, Promoter)Anna Bakst(Executive Officer, Director)Rex Liu(Executive Officer)David Williamsonin

BoardAndras Forgacs(Director, Promoter)Bart Swanson(Director)in

Co-investorsArtis VenturesAstanor VenturesBreakout LabsHorizons VenturesInventus Capital PartnersKohala Ventures+4 more

Noetik builds AI models to identify cancer patients most likely to respond to treatments and to discover new oncology drug targets.

AI & Machine LearningBiotechHealthtechSouth San Francisco, US

Jacob Rinaldi(Executive Officer, Director, Promoter)Ronald Alfa(Executive Officer, Director, Promoter)Ron Alfa, MD, PhD(Founder)in

BoardJames Hardiman(Director)inAmy Schulman(Director)in

Co-investors11.2 CapitalLinearis VenturesNorth South VenturesCatalio Capital ManagementDCVC (Data Collective)EPIC VENTURES+2 more

Quince Therapeutics is a clinical-stage biopharmaceutical company developing eDSP, an investigational therapy studied in a Phase 3 clinical trial (NEAT) for patients with Ataxia-Telangiectasia (A-T).

BiotechHealthtechWest Lafayette, US

Philip S. Low, Ph.D.(Executive Officer, Director)David Lamond(Director)Daniel Hasler(Director)Dirk Thye, M.D.(Executive Officer, Director)William J. Rutter(Director)Alex Andrianopoulos(Director)

Co-investorsElevate VenturesPfizer Venture Investments

Parallel Bio develops human immune organoids and computational tools to predict drug efficacy across diverse patient populations, replacing animal testing in drug discovery.

AI & Machine LearningBiotechDeep TechHealthtechSan Francisco, US

Robert DiFazio(Founder)inJuliana Hilliard(Founder)in

Co-investorsAIX VenturesHumba VenturesImmeasurableJulian CapitalMetaplanetSpacecadet Ventures+5 more

Passkey operates Locksmith, a computational platform that uses human genetics, biology, and pharmacology to identify synergistic drug combinations from approved and late-stage drugs, allowing existing assets to be repurposed for new indications.

AI & Machine LearningBiotechDeep Tech

Co-investorsBison VenturesWireframe Ventures

Phantom Neuro develops a minimally invasive, subcutaneous muscle-computer interface that uses under-the-skin sensors and on-device AI to translate muscle signals into control commands for robotic devices.

AI & Machine LearningBiotechMedical DevicesRoboticsAustin, US

Connor Glass(Executive Officer, Director, Promoter)in

BoardD.A. Wallach(Director)inEdward Michael(Director)inRobert Lord(Director)in

Co-investorsDraper AssociatesLionBirdTime BioVentures

Reach Industries builds frontier technologies for scientific and industrial work, starting with a visual AI copilot for laboratories.

AI & Machine LearningBiotechDeep TechRoboticsLondon, GB

Chris Beck(Founder)inSilas Adekunle(CEO)in

Co-investorsEntrepreneur FirstLunar Ventures

ShiraTronics is a medical device company developing an implantable device to treat chronic migraine disease.

BiotechHardwareHealthtechMedical DevicesBrooklyn Park, US

Robert Binney(Executive Officer, Director)

BoardJoyce Erony(Director)inZack Scott(Director)Brad Vale(Director)inCasey Tansey(Director)Mudit Jain(Executive Officer, Director)

Co-investorsAmzak HealthAPERTURE Venture PartnersGlobal BioAccess FundNorwest Venture PartnersOSF VenturesSeroba Life Sciences+3 more

Surf Bio is a preclinical biopharmaceutical company developing its SnapShot technology, which uses a proprietary polymer to create ultra-high-concentration antibody and biologic formulations (600+ mg/mL, doses over 1,000 mg) for delivery via a standard autoinjector.

BiotechDeep TechHealthtech

Co-investorsPantera Capital

A biotech company developing novel biologics designed to target and eliminate the drivers of cancer recurrence and metastasis.

Biotech

Co-investorsPfizer Venture InvestmentsTaiho Ventures, LLC

ZymoChem develops bio-based materials using proprietary Carbon Conserving (C2) microbes that convert renewable feedstocks into high-value materials with increased yields.

BiotechCircular EconomyClimate TechNew MaterialsSan Leandro, US

Harshal Chokhawala(Founder & CEO)

Co-investorsAccelr8Breakout LabsCavallo VenturesDudley FundFreshTracks CapitalPrime Partners+7 more