Virgo
Techstars '17San Francisco, US · Founded 2022 · Tennessee LLC · 33 employees on LinkedIn · 5 known investors
Virgo develops foundation models and AI software for endoscopy, enabling gastroenterologists to analyze colonoscopy videos for diagnostic scoring, patient outcome prediction, and clinical trial acceleration. The platform serves healthcare providers, researchers, and clinical trial sponsors in gastroenterology.
Also known as Virgo Surgical Video Solutions · Virgo Surgical Video Solutions, Inc
Founders & leadership
Virgo was founded in 2022 by Matt Schwartz.
Investors · 5
Also in the syndicate · 1
Reported raises · per SEC filings
Form D private placements▶Undisclosed amountofferedAug 2022 · Business ServicesRule 506(b)
- Paul Thomas CroftExecutive Officer
- Jonathan FrostExecutive Officer
- Minimum investment
- $1
- Incorporated
- Limited Liability Company, Tennessee, 2022
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Company profile
researched Aug 2026Virgo, legally Virgo Surgical Video Solutions, Inc, develops artificial intelligence models and cloud software for endoscopic medicine. Its core research asset is EndoDINO, a self-supervised vision foundation model for endoscopy, pretrained on 130,037 endoscopy videos and 3.5 billion frames, which the company describes as the largest endoscopy pretraining corpus in the literature. EndoDINO produces reusable embeddings from raw procedure video intended to support multiple downstream tasks including endoscopic disease scoring, lesion detection, outcome prediction and biomarker discovery. The company markets EndoML, a platform launched in 2025 that is powered by EndoDINO.
Alongside the model work, Virgo operates a cloud platform for capturing, managing and analyzing endoscopy video, used by academic medical centers, integrated health systems and private practice networks, with direct integrations to electronic health record systems. In 2021 the company launched VirgoTrials, a tool set that helps pharmaceutical trial sponsors and participating sites accelerate patient recruitment and shorten enrollment periods, initially focused on inflammatory bowel disease studies. Virgo positions its capabilities around AI-enabled clinical trial design and measurement, including controlling for placebo response variability, precision enrichment of likely responders, generation of Bayesian real-world data priors, and continuous AI scores for ulcerative colitis and Crohn's disease endoscopic healing beyond ordinal Mayo and SES-CD scales. The platform also serves gastroenterologists and pulmonologists for research, multi-center collaboration, video assessment and training.
Founding story
Matt Schwartz is identified as founder and CEO. The initial concept, per the company's Gust profile, was a platform to let hospitals automatically record, store and use surgical video for quality control, standardized HIPAA-compliant recording, and surgeon and resident training and research.
Business model
Virgo sells software and AI analysis capabilities to healthcare providers for endoscopy video capture and management, and to pharmaceutical trial sponsors and trial sites through the VirgoTrials clinical trial acceleration offering. The company also engages research partners around its foundation model work.
Sources indicate a platform sold to healthcare providers and pharmaceutical trial sponsors; specific pricing or contract structures are not stated.
Traction
Virgo reports underlying data from 148 US medical centers covering more than 3 million US procedures. At UEGW 2025 the company presented analysis of the UNIFI Phase 3 ustekinumab ulcerative colitis trial showing EndoDINO video embeddings predicted eight-week endoscopic healing from baseline video with AUROC of 0.78 in the placebo arm and 0.75 in the treatment arm, versus 0.70 and 0.72 respectively for 21 standard UC clinical covariates; the company estimates that incorporating this approach into UNIFI's design could have saved seven months and avoided $38 million in cost. At the time of its Series A the company stated it was partnered with multiple pharmaceutical trial sponsors and deployed across academic, integrated and private practice provider settings.
Latest developments
In January 2025 Virgo published an arXiv paper on EndoDINO and announced EndoML powered by EndoDINO, followed by an EndoML platform launch at DDW in May 2025. Data on predicting endoscopic healing in the UNIFI Phase 3 trial was presented at UEGW 2025. In April 2026 the company announced a partnership with the Rajpurkar Lab on a next-generation endoscopy AI foundation model, and it appeared in Elion Health's foundation model market map in January 2026.
▸Full profile — market position, technology, go-to-market, geography, history, risks & controversies
Market position
Virgo describes itself as the leading cloud video and AI platform for endoscopic medicine and benchmarks EndoDINO against endoscopy foundation models from Roche (Etro), Johnson & Johnson (ArgesFM), EndoFM, GastroNet-5M and DovaVision, reporting larger pretraining scale and higher benchmark scores than these comparators. The company was included in Elion Health's Foundation Model Platforms and APIs market map (January 2026) and in a Navistrat Analytics AI in Endoscopy market report (2026).
Virgo's stated differentiation is the scale and diversity of its endoscopy pretraining dataset, state-of-the-art benchmark results using frozen features rather than task-specific supervised training, a single reusable representation layer applicable across scoring, detection, prediction and biomarker discovery tasks, and an installed base of video capture infrastructure across US endoscopy sites that feeds both clinical and trial use cases.
Technology
The company's technology centers on EndoDINO, a ViT-g/14 vision transformer trained with self-supervised learning on unlabeled endoscopy imagery. The pipeline captures raw endoscopy procedure video, extracts, deduplicates and curates frames, pretrains at population scale, and outputs a reusable embedding for downstream tasks. Reported pretraining scale is 130,037 videos and 3.5 billion frames, described as 57x more frames than the next-largest cited dataset. On HyperKvasir three-class Mayo endoscopic scoring with a frozen backbone and linear probe, EndoDINO ViT-g/14 reports macro F1 of 0.748, above cited comparator figures for DINOv2 ViT-g/14 (0.735), supervised DenseNet (0.729), Roche's Etro (0.706) and EndoFM (0.699). The model also produces four-class Mayo endoscopic scores from frame-level predictions aggregated per procedure. Underlying data is drawn from 148 US medical centers and more than 3 million US procedures, with 46.6% non-White representation and a reported Shannon diversity index of 0.713.
Go-to-market
Virgo distributes its video capture and management platform directly to provider organizations, emphasizing scalable multi-facility deployment and EHR integration, and partners with pharmaceutical trial sponsors for recruitment acceleration. The company builds visibility through peer-reviewed and preprint publication (EndoDINO on arXiv), conference presentations at DDW and UEGW, press releases, industry podcasts, and a research contact channel on its website.
Academic medical centers, integrated health systems and private practice provider networks; gastroenterologists and pulmonologists; pharmaceutical clinical trial sponsors and their participating trial sites.
Geography
Operations and data are centered in the United States, with underlying data drawn from 148 US medical centers; press materials reference Carlsbad, California, and the company portal is operated by Virgo Surgical Video Solutions, Inc. The company has stated plans to expand distribution both domestically and internationally.
History
A Gust company profile lists Virgo as founded in October 2016 in San Francisco as a hardware and software platform for automatic recording, storage and use of surgical video, with the stated aims of improving operating room quality control, standardizing HIPAA-compliant surgical video recording, and improving access to surgical video for training and research. The company subsequently focused on endoscopy, launching VirgoTrials for clinical trial recruitment in 2021 and closing a Series A led by FCA Venture Partners. From January 2025 it began publicizing its EndoDINO foundation model, including an arXiv paper (January 2025) and the EndoML platform launches announced in January and May 2025.
Risks & controversies
Virgo has published a notice that individuals have impersonated Virgo recruiters, stating that the company emails only from @virgosvs.com, conducts interviews on Google Meet, and never asks candidates to pay for equipment or supply banking or tax details. Several headline performance claims, including the UNIFI cost and timeline savings, are retrospective modelling presented by the company rather than prospective validation.
Compiled by commissioned research from 8 cited public sources — announcements, filings, and press listed under research sources below.
Key figures
latest reportedCompany-reported or press-reported figures, each dated to when it was claimed — not independently audited.
Competitors · 1
by search overlapCompanies competing with Virgo for the same Google search keywords, organic and paid, via search-intersection analysis.
Timeline · 7
launches, deals, and filingsVirgo presented data at UEGW 2025 showing EndoDINO could predict placebo responders and 8-week endoscopic healing from baseline colonoscopy videos in the UNIFI Phase 3 ulcerative colitis trial.
Virgo launched VirgoTrials, a suite of tools helping pharmaceutical trial sponsors and participating trial sites accelerate patient recruitment and shorten trial enrollment periods.
Dated company events from announcements, filings, and press; legal rows summarize public dockets and regulator releases.
Legal entities · 1
corporate structureIn the news
▸Research sources · 8
primary sources listed
- Virgovirgosvs.com · web
8 public sources were cited for this profile; the first-party ones are listed here.
Frequently asked questions
- What does Virgo do?
- Virgo builds endoscopy foundation models and cloud video software for GI diagnostics, outcome prediction and clinical trials.
- Who founded Virgo?
- Virgo was founded by Matt Schwartz in 2022.
- Who are Virgo's investors?
- Virgo's investors include Celtic House Asia Partners, Cerity Partners Ventures, FCA Venture Partners, Techstars.
- Where is Virgo headquartered?
- Virgo is headquartered in San Francisco, US.



