Steve Paul
InvestorFounderVenture Partner at Third Rock Ventures · Founder, Board Chair at Seaport Therapeutics
East Coast
Writes $100K – $5M checks · typically $1.5M
FoundedSeaport Therapeutics
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About
Steve Paul is a physician-scientist with over 40 years of experience in neuroscience, molecular neuropharmacology, and CNS drug discovery and development. He spent 18 years at the NIH, including as scientific director of the National Institute of Mental Health, followed by 17 years at Eli Lilly and Company where he rose to Executive Vice President for Science and Technology and President of the Lilly Research Laboratories. He co-founded several CNS-focused biotech companies, including Sage Therapeutics, Voyager Therapeutics (where he was president and CEO), and Karuna Pharmaceuticals (where he served as CEO and chairman). He first joined Third Rock Ventures in 2010 and returned in 2018 as a venture partner, and remains a professor of psychiatry and neurology at Washington University in St. Louis School of Medicine.
Beyond investing
- Founded
- Is the scientific co-founder of Sage Therapeutics. Co-founded Voyager Therapeutics, a CNS gene therapy company.
- Education
- Earned a B.A. in Biology and Psychology from Tulane University. Received an M.S. from Tulane University School of Medicine. Received an M.D. from Tulane University School of Medicine.
- Boards
- Serves as Chairman of the Board of the Foundation for the NIH (FNIH). Served on the National Institute of General Medical Sciences (NIGMS) and National Institute of Mental Health Advisory Councils. Was appointed to the Advisory Committee to the Director of the NIH from 2001-2006. Served on the science board of the FDA from 2012-2014.
- Awards
- Is an elected fellow of the American Association for the Advancement of Science. Is a member of the National Academy of Medicine of the National Academy of Sciences. Is an elected fellow emeritus of the American College of Neuropsychopharmacology (ACNP) and served as its President in 1999.
- More
- Has authored or co-authored more than 550 papers and book chapters.
Mentioned above: the Tulane University mafia → · the Sage Therapeutics mafia →
From Steve's own website — common ground for a warm intro.
Founder, Board Chair at Seaport Therapeutics
Intro paths
In turn, Steve can intro founders to Seaport Therapeutics's investors below.
Seaport Therapeutics's investors · 10
Co-founders at Seaport Therapeutics

Investments
Board seats
Karuna TherapeuticsRapport TherapeuticsSage Therapeutics
Investor
Karuna TherapeuticsRapport TherapeuticsSage TherapeuticsVoyager Therapeutics, Inc.
Sources: the investor's own website · curated public sources.
Colleagues at Third Rock Ventures
Frequently asked questions
- Who is Steve Paul?
- Steve Paul is a physician-scientist with over 40 years of experience in neuroscience, molecular neuropharmacology, and CNS drug discovery and development. He spent 18 years at the NIH, including as scientific director of the National Institute of Mental Health, followed by 17 years at Eli Lilly and Company where he rose to Executive Vice President for Science and Technology and President of the Lilly Research Laboratories. He co-founded several CNS-focused biotech companies, including Sage Therapeutics, Voyager Therapeutics (where he was president and CEO), and Karuna Pharmaceuticals (where he served as CEO and chairman). He first joined Third Rock Ventures in 2010 and returned in 2018 as a venture partner, and remains a professor of psychiatry and neurology at Washington University in St. Louis School of Medicine.
- Where does Steve Paul work?
- Steve Paul is Founder, Board Chair of Seaport Therapeutics and Venture Partner at Third Rock Ventures.
- What check size does Steve Paul write?
- Steve Paul typically writes checks of $100K – $5M.
- What companies did Steve Paul found?
- Steve Paul founded Seaport Therapeutics.
- What boards does Steve Paul sit on?
- Steve Paul holds tracked board seats at Karuna Therapeutics, Rapport Therapeutics, Sage Therapeutics.
- What companies has Steve Paul invested in?
- Investments tracked here include Karuna Therapeutics, Rapport Therapeutics, Sage Therapeutics, Voyager Therapeutics, Inc..
- What awards has Steve Paul received?
- Is an elected fellow of the American Association for the Advancement of Science. Is a member of the National Academy of Medicine of the National Academy of Sciences. Is an elected fellow emeritus of the American College of Neuropsychopharmacology (ACNP) and served as its President in 1999.
Founder mafias
Tulane University mafia61
Also came through, then founded or led a company.
Third Rock Ventures mafia33
Also came through, then founded or led a company.
Sage Therapeutics mafia6
Also came through, then founded or led a company.
Voyager Therapeutics, Inc. mafia5
Also came through, then founded or led a company.
Seaport Therapeutics mafia3
Also came through, then founded or led a company.
About this profile. Compiled from public sources — Third Rock Ventures's own website and public professional profiles — and summarised by Fundraising Fox; every fact is kept with where it came from. Spotted an error, or would rather not be listed? Email privacy@fundraisingfox.com · How we build profiles · Your rights


































