National Science Foundation — 2022 Investments
138 investments dated 2022 · listed companies and verified rows first · show all
Nextiles is a materials science company that combines patented fabric-based sensor and sewing technology with a data analytics platform to measure human performance, capturing forces, range of motion, and 3D motion from compression clothing.
HardwareNew MaterialsSports TechBrooklyn, US
George Sun(Chief Executive Officer)John Peters(Director)Matthew Evans(Executive Officer)
BoardMeredith McPherron(Director)in
Co-investorsDrive by DraftKingsPhoenix Capital Ventures
Sensible Weather offers a Weather Guarantee product that automatically reimburses travelers up to 100% of their daily rate or booking cost when qualifying weather (such as rain or excessive heat) occurs during trips or outdoor activities like camping, golf, ski trips, theme parks, and concerts.
Climate TechInsurTechTravel & HospitalitySanta Monica, US
Nicholas Cavanaugh(Executive Officer, Director, Promoter)Nick Cavanaugh(Founder)Heidi A. Lawson(Director)
BoardJay Ganatra(Director)in
Co-investorsAmex VenturesInfinity VenturesWonder Ventures75 & SunnyInfinity VCWalkabout Ventures Llc
4D Avionic Systems develops MissionClear, a UAV coordination engine that automatically detects and resolves conflicts in multi-drone missions before takeoff, working alongside the QGroundControl-4D ground control software.
Defense TechRobotics
Aerosens builds IoT platforms for the aviation industry using Bluetooth Low Energy (BLE) sensors paired with smartphones or tablets.
HardwareIoTSaaS
Co-investorsFlorida Funders
AirMettle develops software that accelerates big data analytics by performing operations such as selecting, grouping, and aggregating data directly in the data lake using parallel processing, instead of moving data to analytic memory or a data warehouse.
Cloud ComputingData & InfrastructureEnterprise Software
Amphix Bio develops peptide therapeutics based on a supramolecular chemistry platform that forms nanostructure scaffolds to activate regenerative signaling in cells and tissues.
BiotechDeep TechChicago, US
Samuel Stupp(Co-founder & Chief Scientific Officer)Nicholas Sather(Executive Officer, Director)Nick Sather(Co-founder & Chief Executive Officer)Dévora Grynspan(Co-founder, Board Observer & Secretary)
BoardKok-Wai Wong(Director)Stephen R Wilson(Director)
Aren offers a patented software toolset that uses computer vision and machine learning to detect, quantify, and track damage on civil infrastructure assets such as bridges, producing 3D digital twins and predictive maintenance and capital allocation plans.
AI & Machine LearningConstruction TechDeep TechSaaSNew York, US
Ali Khaloo(Executive Officer, Director)inEdgar Erasto Martinez Ceja(Executive Officer, Director)
BoardPramod Reddy(Director)
Co-investorsMaccabee VenturesShadow VenturesGreen Egg Ventures
ARIX combines robotics and data analytics to inspect and manage critical industrial assets.
AI & Machine LearningDeep TechEnergyIoTRoboticsJackson, US
Dianna Liu(President and CEO)
Co-investorsAlleyCorpContour Venture PartnersDorm RoomEnergy Transition VenturesInnovation Catalystkineo finance+4 more
Assistance in Motion is a startup developing the WeeBot, a hands-free robotic mobility device that infants as young as six months can learn to drive using a weight-shift control method.
Digital HealthMedical DevicesRobotics
Carole Dennis(Co-founder)Sharon Stansfield(Co-founder)Chuck Schwerin(Co-founder)
Co-investorsConnecticut Innovations
Boston Geospatial provides geospatial intelligence tools for risk screening, near real-time alerts, and monitoring of natural and anthropogenic threats such as geohazards, flooding, and fire.
Climate TechData & InfrastructureSpace Tech
Co-investorsCapital InnovatorsEniac VenturesFour Acres Capital
Gallery San Isabel is an art gallery that promotes creativity in education, featuring art, music, and film venues and offering professional development for teachers and administrators around teaching creativity.
EdTechMedia & Entertainment
Theresa Ferg Brownback(Owner)
Cache develops biopreservation reagents that enable room-temperature storage and access for DNA, RNA, and other biosamples without cold-chain infrastructure.
BiotechDeep TechHealthtech
Co-investorsFifty YearsHAWKTAILJuniperLifeX VenturesTrousdale VenturesValkyrie
Cambrian Works builds networking and connectivity infrastructure for satellite communications and space operations, including the GigRouter, a space-ready router and edge-computing device with onboard AI/ML processing.
Deep TechHardwareSpace Tech
Co-investorsCreative Destruction Lab (CDL)
Dover, US
Kevin O'Connor(Executive Officer, Director)inDavid Schroeder(Director)
Carenostics builds an AI assistant purpose-built for organ transplant care, covering the full patient journey from referral, evaluation, and listing through waitlist maintenance and post-transplant monitoring.
AI & Machine LearningDigital HealthHealthtechBerwyn, US
Bharat Rao(Co-Founder, President & Chief AI Officer)Kanishka Rao(Co-Founder & Chief Executive Officer)
Co-investorsGreatPoint VenturesGaingelsM13
CoraVie Medical is an early-stage medical device company developing an implantable blood pressure monitoring solution for people living with chronic hypertension.
Digital HealthHealthtechMedical Devices
Aimee Garza(Founder and CEO)Paul A. Sobotka(Chief Medical Officer)Erik Scott(Chief Architect)Steve Schwister(VP Program Management)
Co-investorsGolden SeedsGROOVE CAPITAL
Diamond Age Technology builds digital twin models of physical assets and connects them with operational data, using AI, spatial computing, and extended reality to power dashboards, VR/AR training, and real-time field operations.
AI & Machine LearningEnterprise SoftwareIoTHouston, US
Direct Kinetics (DKS) develops radioisotopic batteries based on beta-emitting isotope power sources, designed to provide continuous power for decades in an ultra-light form factor.
Deep TechHardwareSpace Tech
Co-investorsAggie Angel NetworkHouston Angel Network
Dynamac Microwave develops RF filters using its proprietary Fractional Element Filter Architecture (FEFA) and Multilayer-Air filter technology, fabricating filters in an air dielectric medium across the 1 MHz to 100 GHz range at power levels from milliwatts to kilowatts.
Deep TechHardwareSemiconductors
emTRUTH is a patient data platform that gathers medical records from hospitals, labs, pharmacies, specialists, and portals into a single secure account owned by the patient, who controls consent-based sharing with providers, caregivers, and researchers.
CybersecurityDigital HealthHealthtech
Co-investors4D Capital
Encapsulate develops microfluidics and AI-based technology focused on cancer biology, with a team spanning oncology, bioinformatics, and materials science.
AI & Machine LearningBiotechDigital HealthHealthtechMedical Devices
Armin Rad(Co-founder & CEO)Leila Daneshmandi(Co-founder & COO)Bret Schipper(CMO)John Strahley(CFO)
Co-investorsAmbit Health VenturesConnecticut Innovations
FSB develops low-cost, large-area GaN (gallium nitride) substrates and wafers using remote epitaxy and two-dimensional layer transfer (2DLT) techniques that grow single-crystalline semiconductors on graphene and transfer them to host substrates.
Deep TechNew MaterialsSemiconductors
futuresTHRIVE builds gamified digital mental health screeners (tScreen for ages 5-9 and TweenScreen for ages 9-16) that assess children for issues such as anxiety, depression, grief, and suicidality in under 10 minutes.
Digital HealthHealthtechMental Health
Co-investorsConnecticut Innovations
goTenna builds mesh networking hardware and software for off-grid connectivity in mission-critical operations.
Defense TechHardwareIoTBrooklyn, US
Daniela Perdomo(Executive Officer, Director)
BoardLarry Marcus(Director)John Levy(Director)
Co-investorsCadron Capital PartnersComcast VenturesIronGate Capital AdvisorsLifeX VenturesMarque VenturesNew Leaf Invest+12 more
Grain Weevil makes a robot that moves and manages grain inside storage bins, letting farmers maintain grain conditions and quality without physically entering the bin.
AgTechHardwareRoboticsAurora, US
Chad Johnson(Co-Founder & CEO)Benjamin Johnson(Executive Officer)Ben Johnson(Co-Founder / Chief Innovation Officer)
Co-investorsAg Ventures AllianceHomegrown CapitalInnova Memphis, Inc.Invest Nebraska
GyroPalm builds a patented wrist-worn wearable gesture control system, including the Encore device and Spectrum interface, that lets users remotely control electronics, computers, appliances, drones, IoT devices, and industrial robots through hand gestures.
HardwareIoTRobotics
Insu is a hardware and software product development firm that takes founders and technical teams from concept to manufacturing-ready prototype, handling mechanical, electrical, chemical, software, and industrial engineering plus sourcing and manufacturing planning under one team.
Advanced ManufacturingDeep TechHardware
Kilele Health develops the SunVida platform, a continuous biochemical monitoring system built on aptamer sensor technology in a glucose-monitor-style device format that provides real-time and longitudinal molecular data such as phenylalanine levels.
BiotechDeep TechDigital HealthMedical DevicesOakwood, US
Sven Schreiber(Executive Officer)Brittany Nicole Arde(Executive Officer)Jason Charles Heikenfeld(Executive Officer, Director, Promoter)Andrew David Cothrel(Executive Officer, Director, Promoter)
Co-investorsJumpStart Equity
Landsdowne Labs develops button battery technology that deactivates batteries after accidental ingestion to address health risks.
Deep TechHealthtechMedical DevicesNew MaterialsStamford, US
Jeffrey Karp(Executive Officer, Promoter)Robert Langer(Director, Promoter)Bryan Laulicht(Executive Officer, Promoter)Melissa Fensterstock(Executive Officer, Director, Promoter)
BoardDaniel Goldberg(Director)Patrick O'Neill(Director)
Co-investorsBoston Harbor AngelsConnecticut InnovationsHBS Angels of Boston
Lepidext develops a biocontrol product based on a naturally-occurring corn earworm virus isolate that increases sterility in infected insects, aimed at controlling corn earworm in agricultural crops.
AgTechBiotechLexington, US
Paul Mulhollem(Director)Angelika Fath-Goodin(Co-founder)Gary P Cullen(Director)Bruce Webb(Founder & President)
Co-investorsAg Ventures AllianceBluegrass Angel VentureCultivation Capital
Linebird develops drone-based systems for electric utilities, including the Osprey Nonconductive Payload System and an aerial ohmmeter for contact testing and health assessment of live transmission infrastructure.
EnergyHardwareRoboticsRichmond, US
Lee Corbin(Co-founder)inDavid Schul(Co-founder)inChase Coble(Co-founder)inMichael Beiro(Co-founder)in
Co-investorsLighthouse Network Ventures LlcVirginia Venture Partners
Liv Labs develops pelvic floor fitness products, including the Pippa® Resistance Spring, designed to improve pelvic floor strength for women.
FemTechHardwareHealthtechWellness & FitnessChicago, US
Melody Roberts(Founder)inCarly Price(Founder)inDr. Melissa Stendahl(PT, Co-leader)in
Co-investorsY Combinator
BiotechAmbler, US
Thomas Tillett(Executive Officer, Director)
BoardChristopher M. Cashman(Director)
Mycologics develops natural product-based biofungicides that target soil-borne and foliar fungal diseases in food and feed crops such as corn, sugar beets, and cucurbits.
AgTechBiotechClimate TechDurham, US
Anindya Chanda(Founder)
Co-investorsAg Ventures AllianceAgLaunch AcceleratorIDEA NC
Nano-Product Engineering (NPE) is an R&D and commercialization company developing plasma-based surface engineering processes, including patented hybrid PVD/PACVD coating systems (LAFAD and FAAMS), PACVD reactors for diamond coatings and ceramic powders, and arcjet/hybrid thrusters.
Advanced ManufacturingDeep TechNew MaterialsLafayette, US
NasaClip is a hands-free nosebleed treatment device that applies adjustable external compression with medicatable intranasal sponges, developed by an emergency physician.
ConsumerHealthtechMedical Devices
Elizabeth Clayborne(Founder)
Co-investorsCitrine AngelsD3VCMaryland TEDCOPortfoliaTEDCOUrban Entrepreneurs Fund
NeuroGevity develops a sleep headband with biometric sensors and AI algorithms to assess brain health and detect neurophysiological biomarkers at home.
AI & Machine LearningBiotechDigital HealthHardwareHealthtechWellness & FitnessSanta Fe, US
Karen Crow(Executive Officer, Director)Barry Jason Worchel(Executive Officer, Director)
Co-investorsTechstars
Neurosmart makes a wearable band and mobile app that measure real-time physiological stress signals (GSR/EDA, heart rate and HRV, motion) and combine them into a proprietary composite "NeuroScore" with AI-driven intervention protocols.
Digital HealthHardwareWellness & Fitness
OceanMotion develops products that convert and store wave energy, serving scientific and oceanographic observation, maritime and offshore aquaculture monitoring, and maritime security, defense, and ISR applications.
CleantechDefense TechEnergy
OffWorld develops AI-powered swarm robotic systems that use multiple coordinated robots for precision mining of deep underground orebodies, with planned applications in processing, manufacturing, construction, and eventually space resource extraction.
AI & Machine LearningRoboticsSpace Tech
Co-investorsStarbridge Venture Capital Llc
OmicsCraft provides AI-powered software and bioinformatics services for biomedical researchers, centered on its cloud-based aiSysMet platform for building omics data pipelines, metabolite annotation, and multi-omics and biomedical imaging analysis.
AI & Machine LearningBiotechHealthtechWashington, US
Oncurie develops novel chelators that deliver radionuclides to cancer cells, supporting radioligand therapy and molecular imaging for aggressive cancers.
BiotechHealthtechMedical Devices
Jonathan Lindsey(President and Founder)Nick Trotta(Chief Operations Officer)
One Seventeen Media offers reThinkIt!, a mobile mental healthcare product for children that uses data, predictive analytics, and an AI chatbot companion (Minty) to detect emotional needs and support early intervention.
AI & Machine LearningDigital HealthEdTechHealthtechMental HealthAustin, US
Beth Carls(Co-Founder)Amy Looper(Co-Founder)
Co-investorsHealth Wildcatters
Onyx Aerospace is a HUBZone-certified defense contractor providing engineering and analytical services across space and defense domains, including launch vehicle development and human spaceflight, for customers such as the U.S.
Deep TechDefense TechSpace TechHuntsville, US
Open Source Instruments designs and manufactures open-source electronic instruments for scientific research, including wireless implantable biopotential sensors and stimulators for freely-moving animals and optoelectronic alignment devices for particle accelerators and detectors.
Deep TechHardwareMedical Devices
Optical Waters develops OptoStrand, a flexible side-emitting fiber that delivers UV-C germicidal light along its length to disinfect surfaces on contact.
Deep TechHardwareNew Materials
Co-investorsMaroon Venture Partners Fund
Optimizing Mind offers a brain-inspired API for continuous transfer learning that adapts foundational machine learning models to new tasks using a fraction of the data and compute, while avoiding catastrophic forgetting.
AI & Machine LearningDeep TechDeveloper Tools
Orion AI Labs builds multi-spectral visual and RADAR sensing systems for vehicle and vulnerable-road-user (VRU) detection, offering real-time traffic monitoring, collision and near-miss detection, and prediction/warning.
AI & Machine LearningHardwareMobility & Transportation
Paradigm designs and manufactures pollution control devices for diesel and gasoline engines that reduce emissions and particulate matter while lowering maintenance costs and fuel consumption.
Advanced ManufacturingCleantechClimate TechEnergyHardwareRochester, US
John H. Erbland(Founder and CEO)Mike Tschiderer(Executive Officer)
BoardWilliam Carpenter(Director)Robert Poltrino(Director)
Co-investorsBrown and White VenturesLaunch NY
PHYTunes builds Saturn Wi-Fi solutions that deliver low-latency, seamless wireless coverage for mobile applications inside buildings, using simple RF nodes instead of access points to lower deployment costs.
Deep TechHardwareIoT
Co-investorsBosch VenturesRobert Bosch Venture Capital
Piersica develops solid-state lithium-metal batteries based on a proprietary lithium-conductive polymer separator and a fiber-based 3D lithium-metal anode, targeting energy densities around 600 Wh/kg.
CleantechEnergyNew Materials
Joseph B. Schlenoff(Founder)
Co-investorsJuniperSeraph Group
Precient uses naturally occurring microorganisms in a membrane biofilm reactor (MBfR) to remove toxic metals from industrial process water and recover valuable metals such as gold, platinum group metals, rare earth elements, selenium, and uranium.
BiotechCircular EconomyCleantech
Presaj develops a cloud-based clinical decision-support platform that uses AI and engineering techniques to forecast patient-specific risks across procedural, clinical, and social factors for healthcare providers.
AI & Machine LearningDigital HealthHealthtechIowa, US
Co-investorsISA Ventures
Platform for high-throughput material property simulation based on quantum mechanics.
Cambridge, US
Toru Shiozaki(Executive Officer, Director)
BoardGuanhua Chen(Director)Garnet Chan(Director)
Co-investorsAbies VenturesKyoto University Innovation CapitalUTokyo Innovation Platform Co. Ltd.Embark Ventures
Rogue Space Systems designs Orbots—autonomous, reusable spacecraft for rendezvous and proximity operations—and offers orbital services including payload hosting, in-space compute, inspection, last-mile cargo delivery, and space domain awareness.
Deep TechRoboticsSpace TechLaconia, US
SeaSats develops autonomous maritime vessels ("Lightfish" and "Quickfish") for ocean surveillance, intelligence gathering, and domain awareness.
Defense TechIoTRoboticsSan Diego, US
Co-investorsDns CapitalHemisphere Ventures LLCIceNineKonvoy VenturesMonozukuri VenturesRed Beard Ventures+4 more
Sensit Ventures develops and sells custom miniaturized MEMS chemical sensors that detect specific chemicals in the air and transmit data wirelessly.
AgTechDeep TechHardware
Tom Turpen(President & CEO)in
Sequoia Scientific builds instruments and sensors for measuring and characterizing particles in water, including laser diffraction (LISST) instruments, hyperspectral absorption and backscatter sensors, and radiative transfer models used in oceanographic and aquatic research.
CleantechDeep TechHardware
Steam Instruments develops high-spatial-resolution mass spectrometry technology, including ion detectors, ion imaging optics, and high-mass spectrometer designs for applications such as direct-from-tissue biomolecule mapping, ultra-high-mass biomolecule analysis, sub-micron hydrogen and lithium mapping, semiconductor dopant analysis, and nuclear forensics.
BiotechDeep TechHardware
SubSeaSail (SSS) develops Autonomous Undersea & Surface Vehicles (AUSVs) — including the semi-submersible ISR/observation vessel HORUS and the trimaran cargo/energy-delivery vessel HERMES — that are wind- and solar-powered, long-duration, and can operate above and below water to depths of 100 meters.
Defense TechHardwareRoboticsSan Diego, US
Sunchem develops patented processes to recover metals such as gold, copper, silver, and silicon from electronic waste, concentrates, and ore with high purity, using less energy and milder chemicals than smelting or cyanide leaching.
Circular EconomyCleantechNew MaterialsBerkeley, US
Surgivance develops digital pathology imaging technology for analyzing tissue samples with rapid image capture and without calibration requirements.
AI & Machine LearningHealthtechMedical Devices
Co-investorsPortland Seed Fund
SygnaMap uses spatial omics and AI-driven computational pathology to identify molecular biomarkers that map disease pathways, guide therapeutic targets, and monitor disease activity for rare and common diseases.
AI & Machine LearningBiotechDigital HealthSan Antonio, US
Taka Solar (Sunspan) develops a patented solar tube technology that uses an aerodynamic, cable-supported "panel-as-structure" design to lower mounting costs, track the sun without moving parts, and resist soiling.
CleantechEnergyHardware
Chris BarnesDavid Frost
UNIGRID develops energy solutions to address current energy challenges.
CleantechEnergyHardwareSan Diego, US
Co-investorsLG Technology VenturesUnion Square Ventures (USV)Foothill Ventures
Thesis develops reusable, steerable microballoons for routine access to the stratosphere (40,000–130,000 feet), enabling persistent surveillance, communications relay, and atmospheric research for defense, intelligence, commercial, and scientific applications.
AgTechAI & Machine LearningClimate TechData & InfrastructureDeep TechDefense TechInsurTechSpace TechDenver, US
Andrew Antonio(Executive Officer, Director, Promoter)Jared Leidich(Executive Officer, Director, Promoter)Jared Liedich(Executive Officer)
BoardNick Moran(Director)inAlan Eustace(Director)Darren Liccardo(Director)in
Co-investorsCatapult VenturesTechstarsUNION Labs VenturesAltos VenturesDenver VenturesLavrock Ventures+3 more
Vence provides a virtual fencing system for livestock management, using GPS/RF collars and base stations to control cattle movement, set adjustable grazing boundaries, and monitor animal location.
AgTechHardwareIoTKey Largo, US
FRANK WOOTEN(Executive Officer, Director)JASPER HOLDSWORTH(APPOINTMENT EFFECTIVE UPON CONSUMMATION OF THIS FINANCING.)SKY KURTZ(Director)
BoardDHIRAJ SINGH(APPOINTMENT EFFECTIVE UPON CONSUMMATION OF THIS FINANCING.)CURT ROBERT(APPOINTMENT EFFECTIVE UPON CONSUMMATION OF THIS FINANCING.)
Co-investorsiSelect FundSilverstrand CapitalTyche Partners
Yardstick provides tools to measure, plan, and analyze soil carbon data, including instant soil carbon measurement, sample planning aligned with protocols such as Verra VM0042 and CAR SEP, and data mapping and auditing.
AgTechCleantechClimate Tech
Co-investorsWorkshop Venture PartnersCultivian Sandbox VenturesExtantia CapitalToyota Ventures
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.





