Caleb Appleton
InvestorPartner at Bison Ventures · Board director at cosmon · Board director at Sleuth Insights
San Francisco, California
Writes $250K – $10M checks · typically $5M
About
Biomedical engineer turned investor focused on techbio and AI applied to the physical world. Previously invested at Innovation Endeavors, served as SVP/GM at TuneIn, and started his career at Bain & Company. Holds a B.S. in Biomedical Engineering from Georgia Tech.
Contact· self-published, not guessed
Invests in
AI & Machine LearningBiotechDeep TechRobotics
Board director at cosmon
Intro paths
In turn, Caleb can intro founders to cosmon's investors below.
cosmon's investors · 2
Co-founders at cosmon
Board director at Sleuth Insights
Intro paths
In turn, Caleb can intro founders to Sleuth Insights's investors below.
Experience
- Bison VenturesPartnercurrent2024 — presentSan Francisco Bay Area
- Bison VenturesInvestor2023 — 2024
- The Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory UniversityBoard Membercurrent2019 — present
- Eikon TherapeuticsSeed Investorcurrent2021 — present
- TuneInSenior Vice President and General Manager of Global Subscription Business2021 — 2023
- TuneInTechnical Advisor, Chief of Staff to the CEO2021
- Innovation EndeavorsSenior Associate2019 — 2021Palo Alto, California
- Innovation EndeavorsAssociate2017 — 2019
- Bain & CompanyAssociate Consultant2015 — 2017Atlanta
- Bao Laboratory at Georgia TechResearch Assistant2011 — 2015Greater Atlanta Area
Skills & more
+10 more
TeachingCross-functional Team LeadershipMammalian Cell CultureBiomechanicsSports BiomechanicsMicrosoft OfficeMatlabMicrosoft ExcelTeam ManagementExperimentationFrom Caleb's professional profile.
Deals · 2
cosmonBoard seat
via Bison Ventures · filed May 2026 · $31.7M raise
Sleuth InsightsBoard seat
via Bison Ventures · filed Oct 2025 · $7.9M raise
Attribution from SEC filings, press coverage, and firm rosters.
Other disclosed investments
Investor
$RBOTCitrine InformaticsCobotCosmos InnovationDewpoint TherapeuticsEikon TherapeuticsPasskeySkyloVivodyne
Sources: SEC Form D filings · the firm's website.
Colleagues at Bison Ventures
Network3
Investors connected to Caleb in public investor directories — a warm-intro map.
Frequently asked questions
- Who is Caleb Appleton?
- Biomedical engineer turned investor focused on techbio and AI applied to the physical world. Previously invested at Innovation Endeavors, served as SVP/GM at TuneIn, and started his career at Bain & Company. Holds a B.S. in Biomedical Engineering from Georgia Tech.
- Where does Caleb Appleton work?
- Caleb Appleton is Partner at Bison Ventures and Board director at cosmon and Board director at Sleuth Insights.
- What does Caleb Appleton invest in?
- Caleb Appleton invests in AI & Machine Learning, Biotech, Deep Tech, Robotics.
- What check size does Caleb Appleton write?
- Caleb Appleton typically writes checks of $250K – $10M.
- What boards does Caleb Appleton sit on?
- Caleb Appleton holds tracked board seats at cosmon, Sleuth Insights.
- What companies has Caleb Appleton invested in?
- Investments tracked here include $RBOT, Citrine Informatics, Cobot, Cosmos Innovation, Dewpoint Therapeutics, Eikon Therapeutics, Passkey, Skylo, Vivodyne.
- Where did Caleb Appleton go to school?
- Caleb Appleton studied at Georgia Institute of Technology (Bachelor’s Degree, Biomedical/Medical Engineering).
Founder mafias
Georgia Institute of Technology mafia180
Also came through, then founded or led a company.
+ 173 more
Innovation Endeavors mafia4
Also came through, then founded or led a company.
Same school
Also attended Georgia Institute of Technology395
+ 389 more
Shared employers
Also worked at Bison Ventures5
Also worked at The Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University2
Also worked at Eikon Therapeutics2
Also worked at TuneIn9
+ 3 more