Caleb Appleton
InvestorPartner at Bison Ventures
San Francisco, California
Writes $250K – $10M checks · typically $5M
FoundedcosmonSleuth Insights
About
Biomedical engineer turned investor focused on techbio and AI applied to the physical world. Previously invested at Innovation Endeavors, served as SVP/GM at TuneIn, and started his career at Bain & Company. Holds a B.S. in Biomedical Engineering from Georgia Tech.
Invests in
AI & Machine LearningBiotechDeep TechRobotics
Experience
- Bison VenturesPartnercurrent2024 — presentSan Francisco Bay Area
- Bison VenturesInvestor2023 — 2024
- The Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory UniversityBoard Membercurrent2019 — present
- Eikon TherapeuticsSeed Investorcurrent2021 — present
- TuneInSenior Vice President and General Manager of Global Subscription Business2021 — 2023
- TuneInTechnical Advisor, Chief of Staff to the CEO2021
- Innovation EndeavorsSenior Associate2019 — 2021Palo Alto, California
- Innovation EndeavorsAssociate2017 — 2019
- Bain & CompanyAssociate Consultant2015 — 2017Atlanta
- Bao Laboratory at Georgia TechResearch Assistant2011 — 2015Greater Atlanta Area
Education
- Georgia Institute of TechnologyBachelor’s Degree, Biomedical/Medical Engineering
Skills & more
+10 more
TeachingCross-functional Team LeadershipMammalian Cell CultureBiomechanicsSports BiomechanicsMicrosoft OfficeMatlabMicrosoft ExcelTeam ManagementExperimentationFrom Caleb's professional profile.
Same school
Also attended Georgia Institute of Technology206
+ 200 more
Shared employers
Also worked at Bison Ventures3
Also worked at The Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University1
Also worked at Eikon Therapeutics2
Also worked at TuneIn7
+ 1 more
Deals · 2
cosmonBoard seat
via Bison Ventures · filed May 2026 · $31.7M raise
Sleuth InsightsBoard seat
via Bison Ventures · filed Oct 2025 · $7.9M raise
Attribution from SEC filings, press coverage, and firm rosters.
Colleagues at Bison Ventures
Network3
Investors connected to Caleb in public investor directories — a warm-intro map.

















