Upside Partnership
Venture capitalMill Valley · Pre-Seed–Series A · 5 people tracked
Also known as UP HOLDINGS, LLC
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Investment thesis
Upside Partnership invests early, emphasizing that early investing is fundamentally about backing people—specifically 'inevitable Founders' who feel compelled to build their companies. The firm aims to work for founders rather than merely transact with them, pairing founders' freedom to lead with the expertise to mentor them throughout their journey. It frames support as demonstrated behavior rather than a marketing claim. The firm typically writes an initial check of around $500K, reserves roughly 70% of its fund for follow-on support in later rounds, and has been the first institutional investor to commit in more than half of its investments.
Source: firm website, verified Sep 29, 2026.
Team · 5 people
from public directoriesWhat they invest in
from 13 of 16 portfolio companiesEnterprise Software ×7AI & Machine Learning ×6SaaS ×6Fintech ×4Healthtech ×3Cybersecurity ×2HR Tech ×2Advanced Manufacturing ×1
HQs:United States×12
Investments · 16 tracked
founders shown can be your intro pathBy year:2026 · 12021 · 12020 · 12017 · 22014 · 16 dated
AlphaFlow manages portfolios of short-term real estate loans by purchasing loans from bridge lenders who finance fix-and-flip properties, serving both institutional investors and smaller investors through its technology platform.
FintechSan Francisco, US
Ray Sturm(CEO)inBogdan Cirlig(CTO, Vice President of Engineering (FinTech))Amna Pervez(Director, People Operations)Nathan Scharfe(Head of Product and Engineer)Sheryl Friesz(Head of Talent Acquisition)Mike Boyadjian(Dir, People Ops)
Co-investorsFundersClubKnockout CapitalKube VCMetaProp VenturesPoint72 VenturesSand Hill Angels+16 more
Apella provides real-time operating room monitoring and predictive analytics through computer vision and AI integration with EHR systems, helping surgical teams detect delays, optimize scheduling, and improve OR efficiency.
AI & Machine LearningDigital HealthHealthtech
Co-investorsK2 HealthVenturesLayout VenturesOPAMP CAPITALTwine VenturesCasdin CapitalHighlandX+2 more
Apozy builds Airlock, a browser defense platform that uses native browser isolation to disarm malicious websites at the moment a user clicks a link.
CybersecurityEnterprise SoftwareSaaSSan Francisco, US
Erhan Justice(CTO)inRick Deacon(CEO)
Co-investorsBase Venture Management, Inc.HBS Alumni AngelsHemisphere Ventures LLCResolute VenturesY CombinatorAgrolimen Ventures+4 more
Clara Labs provides an AI scheduling assistant that handles meeting coordination by reading email threads and proposing meeting times on behalf of professionals.
AI & Machine LearningEnterprise SoftwareFuture of WorkSaaSSan Francisco, US
Maran Nelson(CEO)inMichael Akilian(CTO)inZain Shah(Machine Learning)
BoardXuezhao Lan(Director)in
Co-investorsY CombinatorBasis Set VenturesDeciensFirst Round CapitalFuel CapitalHaystack+6 more
Command E was a San Francisco startup that built a cross-app desktop search tool, letting users search files and data across apps like Slack, Google Drive, and GitHub via a keyboard shortcut.
Co-investorsAbstract VenturesAmplify PartnersBain Capital VenturesCraft VenturesShrug Capital
Emerge Tools provides mobile performance and competitor analysis tools for iOS and Android development teams, enabling measurement of app size, performance regressions, and competitive benchmarking without requiring source code access.
AI & Machine LearningDeveloper ToolsEnterprise SoftwareLos Angeles, US
Josh Cohenzadeh(Founder)inNoah Martin(Founder)in
Co-investorsMatrixY CombinatorHaystack
Forma provides flexible employee benefits platforms designed for distributed and diverse workforces.
Enterprise SoftwareFintechHR TechSaaS
Jason Fan(Founder)inMax Hsieh(Founder)
Co-investorsAngelPadDesigner FundEmergence Capital PartnersNewView CapitalNimble PartnersRibbit Capital+1 more
Austin-founded location-based social network known for check-ins at "Spots," acquired by Facebook and later revived as an AR app.
Co-investorsAlsop Louie PartnersGV (Google Ventures)Capital FactoryForm CapitalGreylock PartnersJason Calacanis+3 more
Inversion develops spacecraft and systems to establish Low-Earth Orbit as an on-demand logistics network for rapid global transportation and defense applications.
Advanced ManufacturingDefense TechHardwareLogistics & Supply ChainSpace TechLos Angeles, US
Justin Fiaschetti(Founder)inAustin Briggs(Founder)in
Co-investorsSpark CapitalY CombinatorACADEMY INVESTORAIN VenturesDas & Co.Dorm Room+23 more
Laurel & Wolf ran an online marketplace connecting customers with professional interior designers for a flat fee, providing style boards, shopping lists, and floor plans.
West Hollywood, US
Leura Fine(Founder)Brandon Kleinman(Executive Officer, Director)Leura Spielman(Executive Officer, Director)
Co-investorsArena VenturesHalogen Ventures Management Company LlcDraper AssociatesKarlin VenturesSiemer VenturesStructure Capital
Notable Labs operates an automated laboratory that tests combinations of existing drugs against individual patients' blood cancer cells to identify effective treatment options for patients whose cancers have become resistant to standard therapies.
BiotechHealthtechMedical DevicesSan Francisco, US
Matthew De Silva(CEO)inPete Quinzio(Founder)inConnor Warnock(Senior Engineer)Van Duesterberg(Science Consultant)Omid Karkouti(Vice President of Business Development)Scott Patterson(Vice President of Engineering)
Co-investors11.2 CapitalAlumni VenturesBuilders VCFundersClubHemisphere Ventures LLCLifeforce Capital+29 more
Pelica Health builds an AI operating system for value-based care, helping healthcare organizations close care gaps and manage operations across multiple vendor systems.
AI & Machine LearningEnterprise SoftwareHealthtechSaaSSan Francisco, US
Lalit Kundu(Founder)inCatherine Zhao(Founder)in
Co-investorsY CombinatorDentsu VenturesAndreessen HorowitzLlama venturesMatador FundProgressive Ventures+2 more
sFOX is an institutional digital asset infrastructure platform providing enterprise-level access to crypto markets through a unified interface with deep liquidity, trading algorithms, and custody solutions.
Crypto & Web3FintechLos Angeles, US
George Melika(CTO)inAkbar Thobhani(Founder)inJavier Martinez(CEO)inBilal Chinoy(Chief Technology Officer)inDavid Arnold(Chief Financial Officer)inAleksandr Zhuk(Chief Information Security Officer)in
Co-investorsBlockchain CapitalDigital Currency GroupTransmedia CapitalUtopian VenturesY CombinatorBoost VC+6 more
Smyte provides fraud and abuse detection services to online marketplaces and social platforms, using automated classification to identify and block spam, scams, harassment, and payment fraud.
CybersecurityEnterprise SoftwareSan Francisco, US
Pete Hunt(Founder)Julian Tempelsman(Founder)Josh Yudaken(Lead Infrastructure Engineer)inDave Newman(Senior Software Engineer)in
Co-investorsBaseline VenturesFounder CollectiveY CombinatorAvalon Ventures Management, LlcHarrison MetalNotable Capital
Stackpack provides an AI agent for finance teams that manages vendor and AI spend, monitoring contract renewals, analyzing token usage, flagging spend increases, catching unused vendors, routing approvals, and setting budgets.
AI & Machine LearningB2B MarketplacesEnterprise SoftwareFintechSaaSSan Francisco, US
Sara Wyman(Founder)in
Co-investorsLayout VenturesMSIVNomad Venture Partners, LlcElefundFreestyle Capital
Textio offers AI-powered recruiting and feedback tools that help managers, recruiters, and HR teams write job posts, interview documentation, and performance feedback that reduce bias and support employee growth.
AI & Machine LearningHR TechSaaSSeattle, US
Kieran Snyder(Founder)inJensen Harris(Founder)in
Co-investorsBloomberg BetaCowboy VenturesEmergence Capital PartnersOperator CollectiveScale Venture Partners
Exits · 6
1 IPOs · 5 acquisitions · showing 1Command Eacq. by Dropbox
Portfolio news
latest coverage across their companiesPelica · ycombinator.com · Jun 25, 2026
Apella Technology · finsmes.com · Jan 9, 2026
Stackpack · finsmes.com · May 13, 2025
Emerge Tools · emergetools.com · May 6, 2025
Frequently asked questions
- How many investments has Upside Partnership made?
- Upside Partnership has 16 tracked investments, 6 of which have exited, including 1 dated in the last 24 months.
- What stage does Upside Partnership invest at?
- Upside Partnership invests at the Pre-Seed, Seed, Series A stages.
- What is Upside Partnership's typical check size?
- Upside Partnership typically writes checks of $500K.
- What sectors does Upside Partnership focus on?
- Upside Partnership focuses on Sector Agnostic.
- Where is Upside Partnership located?
- Upside Partnership is headquartered in Mill Valley, US.
- Does Upside Partnership lead rounds?
- Upside Partnership typically participates in rounds rather than leading them.
Co-investors · 74
First Round Capital is an early-stage venture firm partnering with founders at the very first stages of company creation, backing companies from angel through seed with hands-on support across GTM, recruiting, and operations.
Spark Capital is a venture capital firm that partners with founders, known for early investments including leading Twitter's Series B in 2008.
Emergence Capital is a venture capital firm that partners with founders building B2B software companies, from early-stage cloud and SaaS pioneers to AI-native innovators.
Andreessen Horowitz (a16z) is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz, known for pioneering the platform model with a large team of operators supporting founders across stages.
Sequoia Capital is a venture capital firm that partners with founders to build technology companies.
GV (Google Ventures) is a venture capital firm that has invested in AI and machine learning since its early days, backing more than 100 AI companies across infrastructure, life sciences, and applications.
Founders Fund is a venture capital firm that backs technology companies building transformative products.
Craft Ventures is a venture capital firm run by a team of former founders, operators, and investors who partner closely with founders to help build and scale technology companies.
Khosla Ventures is a venture capital firm that backs bold, early-stage, technology-driven companies across deep tech and other sectors, providing hands-on 'venture assistance' to help founders build category-defining businesses.
Greylock Partners is an early-stage venture capital firm that partners with founders building companies from inception. Its partners make only one or two new investments per year to focus deeply on each partnership.
Founder Collective is a seed and pre-seed stage venture capital firm that invests across sectors, describing itself as sector agnostic and anti-thematic.
This page announces that GGV Capital split into two separate firms in March 2024: Granite Asia (Singapore, covering APAC) and Notable Capital (US, based in Silicon Valley with offices in San Francisco and New York, investing in the US, Israel, Europe, and Latin America).
▶62 more co-investors
Uncork CapitalOffline VenturesHomebrewCowboy VenturesOperator CollectiveBaseline VenturesGeneral CatalystAccelIndex VenturesRedpoint VenturesLong Journey VenturesBenchmarkFelicis VenturesBoxGroupCoatue ManagementKrakenSound VenturesTrue VenturesBattery VenturesGradient VenturesStreamlined VenturesACME CapitalMayfield FundRRE VenturesSlow VenturesBling CapitalGreycroftC2 InvestmentsForerunner VenturesPrecursor VenturesCaffeinated CapitalSoftBank Vision FundSouth Park CommonsElectric CapitalBullpen CapitalNext47Lowercase CapitalLerer HippeauGoodwater CapitalUS Venture Partners75 & SunnyHustle FundShasta VenturesBetaworks Ventures Management, LlcWorklife VenturesMoxxie VenturesKohlberg Kravis RobertsHeavybitFikaCrosscut VenturesRelay VenturesAltimeter CapitalSignia Venture PartnersG2 Venture PartnersCyfrinKyber Knight CapitalWestern Technology InvestmentActivant CapitalHanaco Venture CapitalWestbound Equity PartnersThayer VenturesDream Machine
Firms observed investing alongside Upside Partnership, from public investor directories. Shared companies are the overlap with Upside Partnership's recorded portfolio.
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