/Companies

MitoRx Therapeutics

Harwell Oxford, GB · Founded 2021 · 6 known investors

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MitoRx is a preclinical-stage biotech developing MTRX31, a first-in-class small molecule that restores mitochondrial metabolism to eliminate ectopic fat in patients with metabolically unhealthy, high-risk obesity. Rather than suppressing appetite, its approach aims to deliver durable weight loss and reduce risks of type 2 diabetes, MASH, and cardiovascular disease.

Founders & leadership

MitoRx Therapeutics was founded in 2021 by Jon R., Jon Rees PhD, and Norman Law PhD.

JRJon R.
Jon R.Co-founder · Chief Executive OfficerJon Rees is the founder and CEO of MitoRx Therapeutics, a preclinical biotech developing mitochondrial-targeted small molecules for weight loss in obesity. A metabolic engineer, he holds a PhD in engineering plant secondary metabolism from Royal Holloway University of London, completed postdoctoral work on primary metabolism at the University of Oxford, and previously helped secure the first venture investment in Ducentis, which was later acquired.
JR
Jon Rees PhDCo-founder & Chief Executive Officer
NL
Norman Law PhDCo-founder, Chief Technology Officer & Head of Intellectual Property

Investors · 6

Funding

SEC filings, press & company announcements
  • Undisclosed amountpre-Series A roundJan 2026
    Source ↗
  • Undisclosed amountpre-series A roundNov 2025
    Source ↗

Source: company announcements and press reports — follow each round's link for the claim.

Companies House · registry record

View on Companies House ↗
Registered name
MITORX THERAPEUTICS LIMITED
Company number
13237941
Status
Active
Company type
Private limited company
Incorporated
2 Mar 2021
Registered office
9400 Garsington Road, Oxford Business Park, Oxford, OX4 2HN
Nature of business (SIC)
72110 — Research and experimental development on biotechnology82990 — Other business support service activities n.e.c.
Previous names
IFFLEY BIOTECH LTD (2021–2021)
Accounts
last made up to 31 Mar 2025 · next due 31 Dec 2026
Confirmation statement
last made up to 1 Mar 2026 · next due 15 Mar 2027

Current officers · 6

  • Pennsec Limited — corporate secretary, appointed 2 Mar 2021
  • Didier Shaun Philip Cowling — director, appointed 12 Nov 2025
  • Glyn Owain Edwards — director, appointed 20 Feb 2022
  • Mohammad Sohail Fazeli — director, appointed 17 Mar 2026
  • Alexander Michael Fink — director, appointed 19 May 2022
  • Jonathan David Rees — director, appointed 2 Mar 2021

Source: Companies House public register · retrieved 27 Sept 2026. Contains public sector information licensed under the Open Government Licence v3.0.

In the news

Frequently asked questions

What does MitoRx Therapeutics do?
MitoRx is a preclinical-stage biotech developing MTRX31, a first-in-class small molecule that restores mitochondrial metabolism to eliminate ectopic fat in patients with metabolically unhealthy, high-risk obesity. Rather than suppressing appetite, its approach aims to deliver durable weight loss and reduce risks of type 2 diabetes, MASH, and cardiovascular disease.
Who founded MitoRx Therapeutics?
MitoRx Therapeutics was founded by Jon R., Jon Rees PhD, Norman Law PhD in 2021.
Who are MitoRx Therapeutics's investors?
MitoRx Therapeutics's investors include Future Planet Capital, Oxford Investment Opportunity Network (OION), Oxford Technology Management, UK Innovation & Science Seed Fund, Empirical Ventures, Wren Capital.
Where is MitoRx Therapeutics headquartered?
MitoRx Therapeutics is headquartered in Harwell Oxford, GB.