LongeVC — Full Portfolio

PreComb is a Swiss biotech company developing its proprietary 3DTwin technology, which combines automated drug testing on patient-derived tumor twins with AI-guided data analysis and response prediction.

AI & Machine LearningBiotechHealthtechMedical Devices

Co-investorsKIKinled Holding

ANI.AI is a San Francisco research lab building a computational platform for longevity medicine that integrates deep multiomics, longitudinal digital phenotyping, and physician-supervised intervention into a unified model of an individual's biological state.

AI & Machine LearningBiotechLongevitySan Francisco, US

BBBruno Balen(Co-Founder, Co-CEO)inNika Pintar(Co-Founder, Co-CEO)in

Co-investorsUNUntapped Ventures

AOA Dx develops a blood-based liquid biopsy platform using mass spectrometry and machine learning to detect ovarian cancer at early stages through tumor-associated biomarkers in serum.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesDenver, US

OPOriana Papin-Zoghbi(Founder)inAFAlex Fisher(Founder/COO)inAJAnna Jeter(Founder)inOriana Zoghbi-Harb(Executive Officer, Director)AMAbigail Mcelhinny(Executive Officer)in

BoardSSSurbhi Sarna(Director)in

Co-investorsALAlleyCorpGOGood Growth CapitalJOJoyance PartnersY Y CombinatorASAstiaAUAurum Venture Partners+19 more

Basepaws offers a DNA testing service for cats that analyzes genetic breed similarity and provides breed breakdown reports for mixed-breed and domestic cats.

BiotechConsumerDirect to ConsumerHealthtechWellness & Fitness

Co-investorsBABand of AngelsCHChloe CapitalIRIrishAngelsPAPasadena AngelsGIGingerbread CapitalINInertia Ventures

Catena develops a conjugation platform for antibody-drug conjugates (ADCs) and multi-payload conjugates used in oncology for solid tumors.

BiotechDeep TechHealthtechMedical DevicesSan Francisco, US

MLMarco Lobba(Founder)inMFMatthew Francis(Founder)in

Co-investorsCICivilization Ventures Management, LlcIAIaso VenturesY Y CombinatorAXAxial VCMBMBX CapitalSOSocial Impact Capital

CatenaBio develops precision conjugation technology using native amino acids to enable biotherapeutic fusions of small molecules, nucleic acids, enzymes, and cells.

BiotechDeep TechHealthtechBerkeley, US

MLMarco Lobba, Ph.D.(Founder)in

Co-investorsFRFREEFLOWCACaffeinated CapitalCICivilization Ventures Management, LlcNYNYBC Ventures

Constructive Bio is a biotechnology company that rewrites the genetic code to give cells access to non-canonical amino acid building blocks, expanding the range of proteins that can be designed, engineered, and manufactured.

BiotechDeep TechNew Materials

JCJason Chin(Professor)

Co-investors+N+ND CapitalAMAmadeus Capital PartnersFIFine Structures VenturesGEGENERAL INCEPTIONOMOMX VenturesPAPaladin Capital Group+3 more

Deep Longevity develops AI-powered aging clocks and health analytics tools that estimate biological age and predict long-term health risks using multi-omics data.

AI & Machine LearningBiotechHealthtechLongevitySaaS

AZAlex Zhavoronkov(Chief Longevity Advisor)inJAJamie Alexander Gibson(Executive Director and Chief Executive Officer)DNDeepankar Nayak(CEO)in

Co-investorsBOBold Capital PartnersKIKickstart Innovation

First Longevity operates a longevity-focused platform, including a daily newsletter covering longevity science, investment, and innovation, and DLT, a data system that tracks longevity companies, signals, and trends.

Data & InfrastructureLongevityMedia & Entertainment

Freedom Biosciences develops neuropsychiatric therapeutics, focusing on novel treatments for conditions including depression, PTSD, and alcoholism.

BiotechDigital HealthMental Health

DJDr. John Krystal(Co-founder & CEO)inDBDina Burkitbayeva(Co-founder)in

Co-investorsBEBeni Venture CapitalEVEvolution VC PartnersITIter InvestmentsMAManta Ray VenturesPSPsyMed VenturesUNUnruly Capital+1 more

Glyphic Biotechnologies develops ProSE™, a high-throughput de novo protein sequencing technology for analyzing proteomes with single-molecule sensitivity.

BiotechDeep TechBerkeley, US

DEDaniel Estandian(Founder)inEd Boyden(Founder)JYJosh Yang(Founder)in

BoardCACraig Asher(Director)inJimmy Yun(Director)in

Co-investorsARArtis VenturesBLBlack FlagCICivilization Ventures Management, LlcFOFoundersX VenturesHAHarpoon VenturesMOModi Ventures+5 more

Haut.AI analyzes skin condition from selfies using proprietary algorithms and recommends personalized skincare products and routines.

AI & Machine LearningConsumerDigital HealthDirect to ConsumerHealthtechWellness & Fitness

Helix Nanotechnologies develops mRNA-based therapeutics for disease treatment and environmental applications, currently advancing a COVID-19 vaccine candidate for immunocompromised patients and testing interventions targeting climate challenges.

AI & Machine LearningBiotechHealthtechBoston, US

NENikolai Eroshenko(Founder/CSO)in

Co-investorsBABascom VenturesBEBeast VenturesCHChampion Hill VenturesDCDCVC (Data Collective)FIFifty YearsHAHAWKTAIL+8 more

This page is a thought-leadership essay by Teymour Boutros-Ghali of Bold Capital Partners arguing that venture investors and foundations should fund the commercialization phase of health-equity-focused life science companies using non-dilutive capital.

BiotechBaltimore, US

Aleksandrs Zavoronkovs(Executive Officer, Director)

Co-investorsB B Capital GroupBOBold Capital PartnersBOBOLD LongevityHAHarmonix FundSQSquareOne Capital

Insilico Medicine uses artificial intelligence to discover and develop new drugs, operating an AI-driven platform for pharmaceutical research and development.

AI & Machine LearningBiotechDigital HealthHealthtechHong Kong

AZAlex Zavoronkov(Director)AZAlex Zhavoronkov(Founder & CEO)inAAAlex Aliper(President)inFeng Ren(Chief Scientific Officer, Executive Director & Co-CEO)in

BoardNisa Leung(Director)Lennart Lee(Director)

Co-investorsLILilly Asia VenturesOROrbiMedQIQiming Venture PartnersWAWarburg PincusBABaidu VenturesEIEight Roads Ventures+9 more

Longenesis operates a platform for health and biomedical data management used to run research studies, including managing study participants across the Baltics and Mediterranean regions.

BiotechCrypto & Web3Digital HealthHealthtech

The Longevity Biotechnology Association is a global non-profit organization that convenes longevity biotech companies, pharmaceuticals, researchers, and investors to establish industry standards and advance the translation of geroscience into therapeutic interventions that prevent age-related diseases and extend health span.

BiotechHealthtechLongevity

Melio develops a rapid bloodborne pathogen testing platform that identifies common pathogens from blood samples within hours, replacing traditional multi-day culture-based diagnostics.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

MSMridu Sinha, PhD(Co-Founder and CEO)Stephanie Fraley, PhD(Co-Founder)

Co-investorsCOCove FundLELexi VenturesACAccelBEBessemer Venture PartnersCACapital One VenturesCOCoatue Management+4 more

Proton Intelligence develops CKM™, a continuous monitoring medical device drawing on biosensing and minimally invasive microdevice technology for clinical use.

Deep TechDigital HealthHealthtechMedical Devices

Co-investors1515th RockAIAIN VenturesTETenmile

Red Queen Bio builds an AI-powered biodefense system that rapidly designs and manufactures countermeasures against emerging biological threats, enabling faster defensive responses to evolving pathogenic risks.

AI & Machine LearningBiotechDefense Tech

HRHannu Rajaniemi(Executive Director)inNENikolai Eroshenko(CEO)in

Co-investorsCOCompoundTHThe Venture CollectiveCECerberus VenturesFIFifty Years

Rubedo Life Sciences develops therapeutics targeting aging by eliminating senescent cells to extend human healthspan.

AI & Machine LearningBiotechLongevityMedical Devices

Co-investorsBEBeiersdorf Innovation FundCDCDP Venture CapitalEVEvolution VenturesKHKhosla VenturesMOModi VenturesMOMoonstone Venture Capital+2 more

Siphox Health develops early diagnostic testing technology to detect and manage chronic diseases at home, delivered as a painless 5-minute test that enables frequent monitoring.

Digital HealthHealthtechLongevityMedical DevicesWellness & FitnessBoston, US

MDMichael Dubrovsky(Co-Founder)inDVDiedrik Vermeulen(Founder)in

Co-investorsDUDuke Capital PartnersNENeer Venture PartnersOVOverlap HoldingsY Y CombinatorBABalaji SrinivasanINInflect Health+4 more

Trogenix develops precision genetic medicines for cancer treatment using proprietary Synthetic Super-Enhancers technology delivered via AAV vectors, targeting solid tumors with personalized in situ vaccinations.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Co-investorsACACADEMY INVESTOR4B4BIO CapitalAIAIN VenturesIQIQ Capital

Trogenix develops precision gene therapies for cancer using its Odysseus platform and Synthetic Super-Enhancer (SSE) technology, engineered DNA elements activated only in diseased cell states to selectively target and kill tumour cells while activating the immune system.

BiotechDeep TechHealthtech

Co-investorsAIAIN VenturesIQIQ Capital4B4BIO CapitalCACalculus Capital Ltd.

Unnatural Products is a drug discovery platform company that develops synthetic macrocycles to target previously undruggable disease targets.

AI & Machine LearningBiotechDeep TechMedical DevicesSanta Cruz, US

CPCameron Pye(Co-Founder & CEO)inJoshua Schwochert(Co-Founder & CSO)in

BoardVBVasudev Bailey(Director)in

Co-investorsABAbstract VenturesARArtis VenturesASAsset Management CompanyBEBetter Ventures Central LlcBLBlue Bear VenturesDRDroia Ventures+6 more

Valink Therapeutics develops bispecific antibody-drug conjugates (ADCs) for therapeutic applications, combining high-throughput discovery, antibody engineering, and medicinal chemistry capabilities.

AI & Machine LearningBiotechHealthtechMedical DevicesBoston, US

ASArne Scheu(Founder)inIKIrsyad Khairil(Founder)in

Co-investorsHOHoxton VenturesMEMetaplanetOXOxonian VenturesP5P53 InvestSYSynBioVenY Y Combinator+1 more