LongeVC — Full Portfolio

PreComb is a Swiss biotech company developing its proprietary 3DTwin technology, which combines automated drug testing on patient-derived tumor twins with AI-guided data analysis and response prediction.

AI & Machine LearningBiotechHealthtechMedical Devices

Co-investorsKIKinled Holding

ANI.AI is a San Francisco research lab building a computational platform for longevity medicine that integrates deep multiomics, longitudinal digital phenotyping, and physician-supervised intervention into a unified model of an individual's biological state.

AI & Machine LearningBiotechLongevitySan Francisco, US

BBBruno Balen(Co-Founder, Co-CEO)inNika Pintar(Co-Founder, Co-CEO)in

Co-investorsUNUntapped Ventures

AOA Dx develops a blood-based liquid biopsy platform using mass spectrometry and machine learning to detect ovarian cancer at early stages through tumor-associated biomarkers in serum.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesDenver, US

OPOriana Papin-Zoghbi(Founder)inAFAlex Fisher(Founder)inAJAnna Jeter(Founder)inOriana Zoghbi-Harb(Executive Officer, Director)AMAbigail Mcelhinny(Executive Officer)in

BoardSSSurbhi Sarna(Director)in

Co-investorsALAlleyCorpGOGood Growth CapitalJOJoyance PartnersY Y CombinatorASAstiaAUAurum Venture Partners+36 more

Basepaws offers a DNA testing service for cats that analyzes genetic breed similarity and provides breed breakdown reports for mixed-breed and domestic cats.

BiotechConsumerDirect to ConsumerHealthtechWellness & Fitness

Co-investorsBABand of AngelsCHChloe CapitalIRIrishAngelsMEMetropolis VCPAPasadena AngelsGIGingerbread Capital+1 more

CatenaBio develops precision conjugation technology using native amino acids to enable biotherapeutic fusions of small molecules, nucleic acids, enzymes, and cells.

BiotechDeep TechHealthtechMedical DevicesBerkeley, US

MLMarco Lobba(Founder)inMatthew Francis(Founder)in

Co-investorsCACALIFORNIA INNOVATIONCICivilization Ventures Management, LlcCRCreative Destruction Lab (CDL)FRFREEFLOWIAIaso VenturesJUJude Gomila+14 more

Constructive Bio is a biotechnology company that rewrites the genetic code to give cells access to non-canonical amino acid building blocks, expanding the range of proteins that can be designed, engineered, and manufactured.

BiotechDeep TechNew Materials

JCJason Chin(Professor)Jason W. Chin(Founder)Julius Fredens(Founder)

Co-investors+N+ND CapitalAMAmadeus Capital PartnersFIFine Structures VenturesGEGENERAL INCEPTIONOMOMX VenturesPAPaladin Capital Group+2 more

Deep Longevity develops AI-powered aging clocks and health analytics tools that estimate biological age and predict long-term health risks using multi-omics data.

AI & Machine LearningBiotechHealthtechLongevitySaaS

AZAlex Zhavoronkov(Chief Longevity Advisor)inJAJamie Alexander Gibson(Executive Director and Chief Executive Officer)DNDeepankar Nayak(CEO)in

Co-investorsBOBold Capital PartnersKIKickstart Innovation

First Longevity operates a longevity-focused platform, including a daily newsletter covering longevity science, investment, and innovation, and DLT, a data system that tracks longevity companies, signals, and trends.

Data & InfrastructureLongevityMedia & Entertainment

philip newman

Co-investors50500 Global

Freedom Biosciences develops neuropsychiatric therapeutics, focusing on novel treatments for conditions including depression, PTSD, and alcoholism.

BiotechDigital HealthMental Health

DJDr. John Krystal(Co-founder & CEO)inDBDina Burkitbayeva(Co-founder)in

Co-investorsBEBeni Venture CapitalEVEvolution VC PartnersITIter InvestmentsMAManta Ray VenturesPSPsyMed VenturesUNUnruly Capital+2 more

Glyphic Biotechnologies develops ProSE™, a high-throughput de novo protein sequencing technology for analyzing proteomes with single-molecule sensitivity.

BiotechDeep TechBerkeley, US

DEDaniel Estandian(Founder)inEd Boyden(Founder)JYJosh Yang(Founder)inJoshua Yang(Founder)

BoardCACraig Asher(Director)inJYJimmy Yun(Director)in

Co-investorsARArtis VenturesBLBlack FlagCICivilization Ventures Management, LlcFOFoundersX VenturesHAHarpoon VenturesMOModi Ventures+7 more

Haut.AI analyzes skin condition from selfies using proprietary algorithms and recommends personalized skincare products and routines.

AI & Machine LearningConsumerDigital HealthDirect to ConsumerHealthtechWellness & Fitness

Co-investorsPHPHD Ventures

Helix Nanotechnologies develops mRNA-based therapeutics for disease treatment and environmental applications, currently advancing a COVID-19 vaccine candidate for immunocompromised patients and testing interventions targeting climate challenges.

AI & Machine LearningBiotechHealthtechBoston, US

NENikolai Eroshenko(Founder)inHRHannu Rajaniemi(Founder)in

Co-investorsALAlumni VenturesBABascom VenturesBEBeast VenturesCHChampion Hill VenturesDCDCVC (Data Collective)FIFifty Years+14 more

Insilico Medicine uses artificial intelligence to discover and develop new drugs, operating an AI-driven platform for pharmaceutical research and development.

AI & Machine LearningBiotechDigital HealthHealthtechHong Kong, US

Aleksandrs Zavoronkovs(Executive Officer, Director)AZAlex Zavoronkov(Director)AZAlex Zhavoronkov(Founder)inAAAlex Aliper(President)inFeng Ren(Chief Scientific Officer, Executive Director & Co-CEO)in

BoardNLNisa Leung(Director)in

Co-investorsLILilly Asia VenturesOROrbiMedQIQiming Venture PartnersWAWarburg PincusBABaidu VenturesEIEight Roads Ventures+13 more

Longenesis operates a platform for health and biomedical data management used to run research studies, including managing study participants across the Baltics and Mediterranean regions.

BiotechCrypto & Web3Digital HealthHealthtech

Co-investorsBIBitfury

The Longevity Biotechnology Association is a global non-profit organization that convenes longevity biotech companies, pharmaceuticals, researchers, and investors to establish industry standards and advance the translation of geroscience into therapeutic interventions that prevent age-related diseases and extend health span.

BiotechHealthtechLongevity

Melio develops a rapid bloodborne pathogen testing platform that identifies common pathogens from blood samples within hours, replacing traditional multi-day culture-based diagnostics.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

MSMridu Sinha, PhD(Co-Founder and CEO)Stephanie Fraley, PhD(Co-Founder)

Co-investorsACAccelCOCove FundGEGeneral CatalystLELexi VenturesBEBessemer Venture PartnersCACapital One Ventures+5 more

Proton Intelligence develops CKM™, a continuous monitoring medical device drawing on biosensing and minimally invasive microdevice technology for clinical use.

Deep TechDigital HealthHealthtechMedical Devices

Co-investors1515th RockAIAIN VenturesTETenmileSOSOSV

Red Queen Bio builds an AI-powered biodefense system that rapidly designs and manufactures countermeasures against emerging biological threats, enabling faster defensive responses to evolving pathogenic risks.

AI & Machine LearningBiotechDefense Tech

HRHannu Rajaniemi(Founder)inNENikolai Eroshenko(Founder)in

Co-investorsCOCompoundTHThe Venture CollectiveCECerberus VenturesFIFifty YearsHAHalcyon Futures InvestmentsOPOpenAI Startup Fund

Rubedo Life Sciences develops therapeutics targeting aging by eliminating senescent cells to extend human healthspan.

AI & Machine LearningBiotechLongevityMedical Devices

Julian Klein(Founder)Marco Quarta(Founder)Mark Gallop(Founder)

Co-investorsALAlumni VenturesBEBeiersdorf Innovation FundCDCDP Venture CapitalEVEvolution VenturesIKIKJ CapitalKHKhosla Ventures+4 more

Siphox Health develops early diagnostic testing technology to detect and manage chronic diseases at home, delivered as a painless 5-minute test that enables frequent monitoring.

Digital HealthHealthtechLongevityMedical DevicesWellness & FitnessBoston, US

MDMichael Dubrovsky(Founder)inDVDiedrik Vermeulen(Founder)in

Co-investorsDUDuke Capital PartnersINIntel CapitalKOKoru CapitalNENeer Venture PartnersOVOverlap HoldingsY Y Combinator+15 more

Trogenix develops precision gene therapies for cancer using its Odysseus platform and Synthetic Super-Enhancer (SSE) technology, engineered DNA elements activated only in diseased cell states to selectively target and kill tumour cells while activating the immune system.

AI & Machine LearningBiotechDeep TechHealthtechMedical Devices

Co-investorsACACADEMY INVESTORAIAIN VenturesCACalculus Capital Ltd.IQIQ CapitalOLOld College Capital4B4BIO Capital

Unnatural Products is a drug discovery platform company that develops synthetic macrocycles to target previously undruggable disease targets.

AI & Machine LearningBiotechDeep TechMedical DevicesSanta Cruz, US

CPCameron Pye(Co-Founder & CEO)inJoshua Schwochert(Co-Founder & CSO)in

BoardVBVasudev Bailey(Director)in

Co-investorsABAbstract VenturesARArtis VenturesASAsset Management CompanyBEBetter Ventures Central LlcBLBlue Bear VenturesCOColorcon Ventures+8 more

Valink Therapeutics develops bispecific antibody-drug conjugates (ADCs) for therapeutic applications, combining high-throughput discovery, antibody engineering, and medicinal chemistry capabilities.

AI & Machine LearningBiotechHealthtechMedical DevicesBoston, US

ASArne Scheu(Founder)inIKIrsyad Khairil(Founder)in

Co-investorsHOHoxton VenturesMEMetaplanetOXOxonian VenturesP5P53 InvestRVRV Invest GmbHSYSynBioVen+9 more