Calculus Capital Ltd. — Full Portfolio

Arctic Shores provides psychometric testing and recruitment tools designed to reduce hiring bias and support diversity goals for businesses.

AI & Machine LearningHR TechSaaS

Co-investorsBeringeaBeringea ProVen VCT

AreCor develops proprietary pharmaceutical products for diabetes, obesity, and cardiometabolic diseases using its Arestat technology platform.

BiotechDeep TechHealthtech

Co-investorsAlbionVCSeneca Partners

UK stem cell company formed by the 2021 merger of Axol Bioscience and CENSO Biotechnologies, supplying iPSC-derived cells and CRO services.

Blu Wireless develops millimeter wave radio networking technology for wireless communications.

Deep TechDefense TechHardwareSemiconductorsBristol, GB

Anthony Murray(Chief Executive Officer)Johnny Bray(Chief Financial Officer)Dave Purle(Chief Operating Officer)Ciara Barron(Director of Marketing)Darren McNamara(Director of Technology Development)Jonathan Rogers(Director of Systems and Platforms)

Co-investorsMaven Capital PartnersCambridge Angels groupSalica InvestmentsARMWren Capital

Bristol-based developer of mmWave wireless communication systems for defence, high-speed rail and other mobility markets.

Co-investorsGuinness VenturesPerscitus LLP

London-based provider of white-label booking, ticketing, CRM, marketing and loyalty software for venues, events and festivals.

UK-Australia independent film and television production company founded in 2021 by Gabrielle Tana, Troy Lum and Andrew Mason.

UK drug discovery company designing small-molecule candidates for immuno-inflammation using molecular design and patient stratification.

UK digital triage and online consultation platform built by NHS GPs, acquired by healthcare AI company Huma in 2024.

EnsiliTech develops ensilication technology, a silica-based method to stabilise vaccines and biopharmaceuticals so they can be stored and transported without refrigeration.

BiotechCleantechDeep TechHealthtechMedical Devices

Asel Sartbaeva(Co-Founder & CEO)Matt Slade(Co-Founder & Chief of Staff)Stephen Wells(Co-Founder & Advisor)Aswin Doekhie(Co-Founder & CTO)Sabine Ficek(CFO)Simon Bennett(Chief Commercial Officer)

Co-investorsElbow Beach CapitalEos Advisory

Essentia Analytics provides behavioral analytics software and performance consulting for professional investors, helping fund managers reduce bias, maintain investment discipline and improve returns.

AI & Machine LearningFintechSaaS

Clare Flynn Levy(CEO)

Co-investorsSalica Investments

UK-based software company whose cloud platform analyses transactions and suppliers to reduce procure-to-pay and supplier risk.

Grateful is a UK cashless tipping and tronc management platform for hospitality and service businesses.

Hinterview is a London-based video and conversation-intelligence platform built for recruitment agencies and talent teams.

UK film and television production company developing and producing feature films and TV series with under-represented creatives.

Invizius develops therapeutics targeting the complement system to treat kidney disease and other disorders driven by uncontrolled immune activation.

BiotechDeep TechHealthtechMedical DevicesGlasgow, GB

Inflection Point Ventures (IPV) is an India-based angel investing platform that pools capital from members to fund early-stage startups.

UK gene control company developing programmable, tunable gene silencing for disease-responsive advanced cell therapies.

Co-investorsMaven Capital Partners

Film and television production company founded by Trudie Styler and Celine Rattray, focused on female-led storytelling.

UK nanotechnology firm making molecularly imprinted polymers as synthetic alternatives to antibodies for diagnostics and bioprocessing.

M0 builds stablecoin infrastructure that lets issuers deploy and interoperate their own dollar-pegged tokens.

UK company operating a platform for buying and selling commercial energy for public and private sector organisations.

Optalitix provides an enterprise platform that consolidates pricing and underwriting workflows, enabling organizations to modernize their pricing models without disruption through incremental cloud migration and governance.

AI & Machine LearningCloud ComputingEnterprise SoftwareFintechInsurTechSaaSLondon, GB

Co-investors24 Haymarket

Oxford BioTherapeutics develops first-in-class oncology therapies—including antibody-drug conjugates (ADC), immuno-oncology, T-cell engagers, and radiopharmaceuticals—using its OGAP-Verify proteomic platform to identify novel cancer targets.

BiotechHealthtech

Co-investorsOxfordPercipient CapitalPerscitus LLP

Quai Network is a scalable, smart-contract-enabled Proof-of-Work Layer-1 built on a multichain blockchain architecture.

UK film and television production company co-founded in 2012 by actor Colin Firth and music executive Ged Doherty.

Resurrect Bio develops genetic disease-resistance traits for crops by restoring plant R-genes, using its FloraFold AI platform and rapid in-planta screening for trait discovery.

AgTechAI & Machine LearningBiotech

Cian Duggan(CEO / Co-Founder)Tolga Bozkurt(Co-Founder)Sophien Kamoun(Co-Founder)

Co-investorsFuture Planet CapitalSynBioVenUK Innovation & Science Seed FundAgFunderPymwymic

Rotageek provides workforce management and scheduling software for rota planning, including demand forecasting, labour modelling, auto-scheduling, time and attendance tracking, and leave management.

AI & Machine LearningFuture of WorkHR TechRetail TechSaaS

Chris McCullough(Co-founder)Roy Pounder(Co-founder)Nick Mann(Co-founder)

Co-investorsVenture FoundersVolution VenturesCalculusGresham HouseGresham House VenturesMobeus Equity Partners

Oxford-based, AIM-listed clinical-stage company developing off-the-shelf active cancer immunotherapies from its Immunobody and Moditope platforms.

An end-to-end mortgage and protection platform that automates the mortgage process and integrates brokers, estate agents, homebuyers and lenders.

Conor Murphy(Founder)in

Co-investorsPembroke VCTLegal & General

AI medical diagnostics company whose DeepView imaging platform predicts whether burns and other wounds will heal.

BiotechDallas, US

J. Michael DiMaio(Executive Officer, Director)John H, Stevens(Director)Erich Spangenberg(Director)

Tagomics develops multimodal technologies for precision medicine and next-generation diagnostics.

AI & Machine LearningBiotechDeep TechMedical DevicesCambridge, GB

Dr Jack Kennefick(Co-founder, Director & Chief Executive Officer)Dr Robert Neely(Co-founder, Director & Chief Scientific Officer)

Co-investorsIllumina VenturesCalculusIQ CapitalMEIF Proof-of-Concept & Early Stage FundMercia VenturesOMX Ventures+1 more

University of Birmingham spinout building a multiomic DNA profiling platform for biomarker discovery and liquid biopsy diagnostics.

Edinburgh biotech developing AAV-delivered synthetic super-enhancer gene therapies for aggressive solid tumours.

Wazoku is a London-based innovation management company combining an AI platform with the Innocentive open-innovation solver marketplace.

Simon Hill(Founder)inRosemarie Diegnan(Founder)in

Co-investorsCambridge Angels groupOctopus VenturesSaaS Capital

Supplies machines and supplies that kill weeds without using herbicides.

Co-investorsBoundary Capital

London-based Wonderhood Studios combines TV production, advertising and audience-data capabilities under founder David Abraham.

WorkL is a UK employee engagement business whose Happy at Work Test measures workplace happiness and powers best-employer rankings.