National Science Foundation — 2023 Investments
119 investments dated 2023 · listed companies and verified rows first · show all
LabForInvention develops energy-efficient, signal-penetrating low-emissivity coatings for windows that reduce building energy consumption while enabling wireless connectivity.
CleantechConstruction TechDeep TechHardwareNew MaterialsFremont, US
Dr. Guowen Ding(Founder and Chief Scientist)
Prenostik offers My Learning Coach, an AI-powered SaaS platform designed for higher education institutions that provides personalized guidance to students while supporting faculty and administrators with data-driven insights.
AI & Machine LearningEdTechSaaS
Patrick Hong(Founder & CEO)Dave Gonzales(Chief Technology Officer)Tim Park(Chief Analytics Officer)
Aepnus is developing a sulfate recycling process that regenerates chemicals on-site from sodium sulfate waste, with a planned demonstration-scale plant designed to process over 500 tonnes of sodium sulfate annually.
Circular EconomyCleantechNew Materials
Lukas Hackl(Founder)inBilen Akuzum(Founder)
Co-investorsClean Energy VenturesCollaborative FundISVLowercarbon CapitalNextFab VenturesThird Derivative+3 more
Agtec Innovations develops smart-release fertilizers, including controlled-release micronutrients, phosphorus products, coatings for DAP/MAP, and caged-urea that reduce nutrient runoff and improve crop yields.
AgTechCleantechNew MaterialsLos Altos, US
Chandrika Varadachari(Executive Officer, Director)inMurli Varadachari(Executive Officer, Director)in
Allium manufactures stainless-clad rebar that meets the AASHTO M 329M standard, offered in a full size range (#3–#18) and ASTM A615 and A706 specifications.
Advanced ManufacturingCleantechConstruction TechNew MaterialsPeabody, US
Steven Jepeal(Cofounder)inSam McAlpine(Founder)in
Co-investorsAera VCAlumni VenturesBay Bridge Ventures ClimateCastor VenturesCreative Destruction Lab (CDL)Propeller VC
Altay Therapeutics develops small molecule inhibitors targeting transcription factors to treat serious diseases including facioscapulohumeral muscular dystrophy and cancer.
BiotechDigital HealthHealthtechMedical DevicesSan Francisco, US
Ali Ozes(Founder)inOsman Ozes(Founder)inJAMES BREITMEYER(Executive Officer, Director)ERIC BJERKHOLT(Director)MIKE GREY(Director)ESTER SKLARSKY(Director)
Co-investorsCreative Destruction Lab (CDL)Jude GomilaTachyon VenturesY CombinatorFshd Global Research Foundation
Lasa Health develops an AI-driven clinical decision support platform to help diagnose and manage chronic pelvic pain, serving healthcare providers and patients in women's health.
AI & Machine LearningDigital HealthFemTech
Margaret Melville(Co-Founder & CEO)Chris Fortuna(Co-Founder & CTO)
Applied Impulse develops impulse-driven manufacturing technology that launches materials at high speed—using methods such as exploding-wire vaporization, electromagnetic solenoid force, and pulsed-laser ablation—to weld, repair, and build metallic parts.
Advanced ManufacturingDeep TechHardware
AsimicA is a B2B strain engineering company that develops Microbial Stem Cell Technology (MiST) to repopulate microbial biofactories with young, productive cells during fermentation, reducing downtime and increasing yields.
AI & Machine LearningBiotechDeep TechNew MaterialsLaramie, US
Nikolai Mushnikov(Founder)inJacob Guidry(Founder)inGrant Bowman(Associate Professor of Molecular Biology)Mark Gomelsky(Professor of Molecular Biology)
Co-investorsSOSV
Blocksynop develops the Neural Blockade Monitor, a noninvasive, real-time device for measuring the effectiveness of local anesthetics (neural blocks) in patients.
HardwareHealthtechMedical Devices
Wayne Sternberger(CTO & Co-inventor)inShari Sternberger(President/CEO)Ellyn Murphy(Senior VP, Marketing)in
Co-investorsMaryland TEDCOTEDCO
Calisbooks develops research-backed early literacy materials and educational content for children from birth through age 6 and beyond, co-designed with leading early learning research institutions.
ConsumerDirect to ConsumerEdTechHardwareMedia & EntertainmentLos Angeles, US
Cali
Calm Waters Group is a climate-focused organization that develops data and AI solutions to support communities taking action on climate change.
AI & Machine LearningCleantechClimate TechData & InfrastructureGovTechImpact & Social Good
Sumeet Sandhu(Founder)in
Carbon Solutions provides consulting, research, and software tools for low-carbon energy technologies including carbon capture, hydrogen, geothermal, and renewable energy.
CleantechClimate TechDeep TechEnergy
Richard Middleton(CEO & Co-Founder)
CarrTech develops FROG (Filter Removal of Glass), an FDA-cleared all-in-one device that combines a filter and hypodermic needle in a single package for preparing injectable medications from glass ampoules.
HardwareHealthtechMedical Devices
Sue Fisher Carr(Founder)inMark Beliczky(CEO)Jack Kent(CCO)John Brzezenski(CFO & Business Strategist)
Co-investorsMaryland TEDCOOld Line Capital PartnersTEDCO
Cartesian develops indoor spatial AI technology for retail operations, using RFID and spatial intelligence to optimize workflows.
AI & Machine LearningDeep TechIoTRetail Tech
Fadel Adib(Co-Founder)Isaac Perper(Co-Founder)
CellChorus develops a visual AI platform called TIMING that performs high-throughput dynamic analysis of single cells, measuring cell activation, killing, and movement over time for biopharmaceutical research.
AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesHouston, US
Dan Meyer(Founder)inNavin Varadarajan(Founder)inLaurence Cooper(Co-founder & Board Chair)inRebecca Berdeaux(Chief Scientific Officer)in
Co-investorsBreakout VenturesHouston Angel NetworkTexas HALO FundY CombinatorAsymmetry Ventures
CurieDx is a screening tool that provides a patient screening interface and provider workflow for medical practices, offered to clinicians across specialties.
Digital HealthHealthtechSaaSBaltimore, US
THERESE CANARES(CHIEF EXECUTIVE OFFICER)inRASHMI SACHAN(CHIEF TECHNOLOGY OFFICER)
Co-investorsCitrine AngelsTEDCO
Earth Mapping International provides geospatial research and engineering services, including GIS, remote sensing, LiDAR, and geodesy, with a current focus on climate-change applications.
AgTechCleantechClimate TechData & InfrastructureDeep TechGovTechUnited States, US
Bishwa Acharya(President and CEO)
Empallo provides telehealth cardiac care led by cardiac specialists, offering treatment plans, medication management, and at-home testing options such as Holter monitoring and sleep studies.
AI & Machine LearningDigital HealthHealthtechMedical DevicesCambridge, US
Co-investorsMilemark Capital PartnersTechstars
Falcon Fuel Cells develops proprietary mobile fuel cell power plants for unmanned aerial vehicles (UAVs), offering higher energy densities than batteries to extend flight times, increase payloads, and lower costs.
CleantechEnergyHardwareRochester, US
Fenix Space develops a reusable tow-launch system that air-launches rockets and hypersonic test vehicles from a towed winged booster.
Space TechSan Bernardino, US
Jason Lee(Executive Officer)inSteve Carter(Director)inMike Gallo(Executive Officer)
BoardDennis Muilenburg(Director)
Co-investorsInnovating CapitalTechstarsNEW VISTA CAPITAL
Fourth Power develops thermal energy storage technology that converts electricity into heat for storage and back to electricity on demand, using high-temperature molten tin and thermophotovoltaic conversion.
CleantechClimate TechDeep TechEnergyHardwareMassachusetts, US
Asegun Henry(Founder)inArvin Ganesan(Founder)in
Co-investorsBreakthrough Energy VenturesDCVC (Data Collective)Munich Re Ventures
Free to Feed provides consulting and advisory support to help parents meet their infant feeding goals.
Digital HealthFemTechHealthtechWellness & Fitness
Trill Paullin(Co-Founder & CSO)Dr. Trillitye Paullin, PhD(Co-Founder & CEO)Dr. LaChiana Hamilton, DNP(Co-Founder & COO)
Co-investorsBeresford VenturesSOSV
Fria makes cooling jewelry using patented hydro-powered technology to provide relief from hot flashes associated with menopause.
ConsumerFemTechHardwareWellness & Fitness
PureBioX uses AI-driven volatile organic compound (VOC) profiling to turn chemical emissions into predictive insights, with products for DNA collection, extraction and purification, rapid microbial detection, and a VOCScan software platform.
AI & Machine LearningBiotechFoodTech
Gaia AI provides AI-powered tools and sensor-based data collection (a wearable backpack and mobile/web apps) for forest inventory and analysis, delivering biometric insights to optimize harvesting, timber sales, and carbon credit strategies.
AgTechAI & Machine LearningClimate Tech
Co-investorsMilemark Capital PartnersSOSVThe E14 FundUbiquity Ventures
gNu Technologies develops technology aimed at improving injection/puncture systems to address technical limitations in drug delivery, targeting applications such as autoinjectors, safety syringes, and specialized needles.
BiotechHealthtechMedical Devices
Harpe Bioherbicide Solutions develops natural, bio-based weed control products for agriculture and, through a partnership with SBM Life Science, the home and garden consumer market.
AgTechBiotechNew Materials
Co-investorsiSelect Fund
Hera Health Solutions is a biotechnology company that develops a proprietary nanotechnology platform to reformulate existing pharmaceutical compounds into more effective and longer-acting therapies.
BiotechDeep TechHealthtechMedical DevicesMemphis, US
Garrett Whitfield(Executive Officer, Director)Idicula Mathew(Executive Officer, Director)
Co-investorsInnova Memphis, Inc.Launch TennesseeTechstarsInnovaMicroVentures
HistoneTx develops precision epigenetic reprogramming therapeutics that use engineered effectors and transient mRNA delivery via non-viral vectors to activate or restore expression of silenced genes without altering DNA.
BiotechDeep TechLongevity
Icorium Engineering develops advanced separation technologies to recover and recycle complex refrigerant mixtures from industrial and commercial systems.
Advanced ManufacturingCircular EconomyCleantechClimate TechLawrence, US
Kalin Baca(Co-Founder & Chief Executive Officer)Mark Shiflett(Co-Founder & Chief Science Officer)Abby Harders(CTO)
IAMECON (Intelligent Analytics and Modeling, Inc.) is a damages expert witness and economic consulting firm that provides litigation support, expert testimony, and computational modeling for law firms, government agencies, and businesses.
AI & Machine LearningData & InfrastructureLegalTechAustin, US
Devrim Ikizler(Founder & Lead Damages Expert)
iTomography develops computed tomography (CT) algorithms and software for CT and microCT scanner manufacturers, enabling improved image quality, artifact reduction, faster image reconstruction, and shortened scan times.
AI & Machine LearningDeep TechMedical DevicesHouston, US
Alexander Katsevich(Chief Technology Officer)Michael Frenkel(President & CEO)
An AI-driven platform that analyzes social media data to provide political campaigns with polling insights, influencer intelligence, and trend forecasting capabilities.
AdTechAI & Machine LearningData & InfrastructureGovTechSaaSNew York, US
Hernan Makse(CEO)Matteo Serafino(Chief Data Scientist)
L5 builds the software intelligence that powers robotic systems for harvesting or handling fruits and vegetables, aimed at addressing labor shortages in agriculture.
AgTechAI & Machine LearningRoboticsLa Canada Flintridge, US
Alexander Gutierrez(Founder and CEO)in
Co-investorsIdeaship
Lakril develops catalytic technologies to convert biomass into renewable chemicals for use as alternatives to petroleum-derived building blocks.
Circular EconomyCleantechDeep TechNew MaterialsChicago, US
Christopher P. Nicholas(Founding Partner / CTO / Director)inPaul J. Dauenhauer(Founding Partner & Chief Technical Advisor)inJustin Brown(CEO / Director)in
BoardLisa Dufresne(Director)inMel Luetkens(Director)inAndy Shafer(Director)in
Co-investorsEvergreen Climate InnovationsGC VenturesService Provider CapitalThe Innovation Space
LATERAL.systems is an AgTech platform that provides data insights to farmers to support sustainable food production.
AgTechAI & Machine LearningData & InfrastructureIoT
Ligero provides payments infrastructure that uses zero-knowledge cryptography to enable private, compliant on-chain transactions for enterprises.
Crypto & Web3CybersecurityFintech
Carmit(Professor at Bar-Ilan University (ZKP/MPC researcher))inMatt DiBiase(Founder)in
Co-investors1k(x)1kxConsenSys MeshDigital Currency Group
Luna Innovations develops fiber optics, nanomaterials, and precision assembly solutions across multiple technical domains.
Advanced ManufacturingData & InfrastructureDeep TechHardwareNew MaterialsRoanoke, US
Scott A. Graeff(Executive Officer, Director)inDavid Chanley(Director)Gary Spiegel(Director)George Gomez-Quintero(Executive Officer)Thomas Oldemeyer(Executive Officer)Brian J. Soller(Executive Officer)
Co-investorsPerot Jain
MarWell Bio develops generative AI technology for antibody drug design, helping accelerate the discovery and development of therapeutic antibodies for treating disease.
AI & Machine LearningBiotechSanta Clara, US
Matmerize offers PolymRize, a no-code polymer informatics platform that uses machine learning and conversational AI to help researchers design and predict properties of new polymers and formulations, including sustainable PET alternatives.
AI & Machine LearningNew MaterialsSaaS
MealMate offers an AI-powered nutrition tracking tool that lets patients log meals via natural language and food images, then estimates nutrients like sodium and calories using USDA food database data.
AI & Machine LearningDigital HealthHealthtech
Mandy Korpusik(Founder and CEO)Eric Speck(Head of Business Development)Hadi Javeed(Chief AI Engineer)Sue Roberts(Nutrition Expert)
Metabob provides a code analysis engine that runs alongside generative AI coding tools, evaluating code in runtime to catch bugs and guide AI assistants toward safer implementation patterns.
AI & Machine LearningDeveloper ToolsSaaS
Co-investorsAntlerFoothill VenturesK20 Fund
Metfora applies metabolite chemistry and data analysis to diagnose cardiovascular and lung disease.
BiotechDigital HealthMedical DevicesIndianapolis, US
BiotechSan Diego, US
Ryan Montes, Ph.D.(Founder)inRyan Montes(Executive Officer, Director)Jason Butler(Executive Officer, Director)
Morningbird Space develops space technologies including additive manufacturing, materials engineering, advanced propulsion, and autonomous in-space construction (its ASCENT drone-based 3D printing initiative), and also makes 3D-printable educational robots (AppBot, AppDog) for STEM learning.
EdTechRoboticsSpace Tech
Motion Grazer AI (SIM) builds vision-based sensing hardware and machine learning algorithms that assess sow reproductive potential, body condition, and locomotion for pork producers with sow breeding operations.
AgTechAI & Machine LearningHardwareEast Lansing, US
Michael Lavagnino(Director)Madonna Benjamin(Director)Daniel Morris(Director)John McIntyre(Founder/CEO and President)
Co-investorsAg Ventures AllianceMichigan Rise
A company developing aerogel-based separator technology for battery safety and fast charging applications.
Deep TechEnergyNew Materials
Co-investorsFoothill Ventures
Nu Planet develops radioisotope production and conversion technologies, focusing on induced decay of Thorium-229 to produce Actinium-225 for targeted cancer therapies, alphavoltaic space batteries, and micro power systems for medical and remote applications.
Deep TechEnergyMedical DevicesSpace Tech
Steven D. Howe, PhD(Founder and CEO)Troy Howe, PhD(Founder)Tom Myers, MD(Founder)Delisa Rogers, MBA(Chief Operations Officer)Kirsten Adams, PhD(VP Radiochemistry)
Osmoses develops a membrane technology for purifying and separating gas molecules, aimed at making industrial gas separation processes more energy-efficient.
CleantechClimate TechDeep TechNew MaterialsBoston, US
Francesco Benedetti(Co-Founder & CEO)inKatherine Mizrahi Rodriguez(Co-Founder & Chief Implementation Officer)inZachary P. Smith(Co-Founder / Associate Professor, MIT)
Co-investorsBlindspot Ventures Management CoCollaborative FundFine Structures VenturesMassVenturesNew Climate VenturesOrbia Ventures+1 more
OtherWordly is a word puzzle game for iPhone and iPad in which players fling clue words into orbiting words with missing letters to solve them across space-themed topics.
EdTechGaming
Pearl Bio develops technologies for genome engineering, ribosome engineering, and biomanufacturing to enable production of novel proteins, chemicals, and materials for biotechnology and medicine.
BiotechDeep TechNew MaterialsStamford, US
Farren Isaacs(Founder)Michael Jewett(Founder)inAmy Cayne Schwartz(Founder)inMerton Gollaher(Executive Officer)
BoardGeorge Church(Science Advisor)Jesse Rinehart(Science Advisor)
Co-investorsKhosla VenturesThe Engine Ventures
Perseus Materials manufactures large-scale composite parts without molds or tooling using fast-curing resins and continuous fibers.
Advanced ManufacturingHardwareNew Materials
Co-investorsAmerica's Frontier FundRoadrunner VenturesLockheed Martin Ventures
Cast Carbon makes plant- and mineral-based wall tiles for biophilic interior design that are biodegradable, fireproof, and carbon negative, and can be composted into soil conditioner at end of life.
Circular EconomyClimate TechConstruction TechNew MaterialsHudson Valley, US
Polymer Solutions Inc develops decomposable and depolymerizable polymer materials and consulting services to help businesses replace conventional plastics with more environmentally friendly alternatives.
Circular EconomyCleantechEnergyNew Materials
Powder Watts develops AI and computer vision technology to optimize rooftop heating cable systems, converting them into distributed energy resources and virtual power plant capacity for utilities and grid operators.
AI & Machine LearningCleantechEnergyIoTPark City, US
The page presents educational or informational content about fluid dynamics and computational fluid dynamics (CFD), describing how engineers use CFD simulations of the Navier-Stokes equations to design systems involving lift, drag, propulsion, cooling, and combustion.
Deep Tech
Radmantis builds uncrewed, modular field-deployable systems that use machine learning image classification to identify and sort individual fish, serving aquaculture facility managers, invasive species control, and utility water-intake protection.
AgTechAI & Machine LearningRobotics
Moira van Staaden(Co-founder & Managing Director)Robert Huber(Co-founder & Senior Researcher)F. Scott Hall(Co-founder & Senior Researcher)
RCE Technologies develops a wrist-worn wearable (Infrasensor) that uses infrared sensors and machine learning to detect signals associated with severe coronary artery occlusion, aiming for earlier heart attack detection.
AI & Machine LearningBiotechDigital HealthMedical DevicesCarlsbad, US
ATANDRA BURMAN(Executive Officer, Director)LOU MALICE(Director)
Co-investorsAtlanta Technology Angels
REEgen uses genetically engineered bacteria to recover rare earth elements and critical metals from ores and industrial by-products such as steel slag, electronic waste, spent catalysts, and coal ash.
BiotechCircular EconomyNew Materials
Co-investorsCollaborative Fund
Remedium Bio is a biotech company developing gene therapy and biologic treatments for osteoarthritis and other rheumatology and metabolic conditions, drawing on research into cartilage regeneration and the FGF18 protein.
BiotechHealthtechLongevityBoston, US
Luppino Francesco(Executive Officer, Director)
Co-investorsLifespan Vision VenturesUlu VenturesHKX Capital
rStream develops automation technology for waste sorting and movement logistics, helping venues, universities, and commercial facilities improve recycling rates and reduce disposal costs while integrating with existing operations.
AI & Machine LearningCircular EconomyCleantechRoboticsAmherst, US
Ian GoodineEthan Walko
Screen360.tv is a subscription-based distance-learning platform that curates international films for K-12 and film education, using foreign films aligned to school curricula (IB, AP, Common Core) to build empathy, language, geography, and cross-cultural understanding among children.
EdTechMedia & EntertainmentSaaS
Catherine (Katy) Kavanaugh(Founder)
Seaflight develops autonomous electric drones and aircraft with advanced aerodynamic technology for cargo logistics and defense applications.
Advanced ManufacturingAI & Machine LearningClimate TechDefense TechEnergyHardwareLogistics & Supply ChainRoboticsSpace TechCarson, US
Graham Doig(Founder)inWill Sutton(Founder)inWilliam Sutton
Co-investorsY CombinatorCollaborative FundEight CapitalGaingelsJude Gomila10X Capital+3 more
SixLine Semiconductor develops carbon nanotube processing and deposition methods to produce semiconductor-grade materials for high-performance, lower-cost semiconductor devices.
Deep TechNew MaterialsSemiconductors
Co-investorsCollaborative Fund
STec develops clean energy propulsion systems and hydrofoil boat designs for the marine industry, including diesel exhaust treatment and hybrid-electric vessels to meet global emissions regulations.
CleantechClimate TechEnergyHardwareBristol, US
Walter Schulz(CEO and Founder)
Co-investorsIllumina Ventures
Sway produces compostable packaging made from seaweed-based materials for brands needing flexible, lightweight single-use alternatives to traditional plastics.
Circular EconomyCleantechClimate TechNew Materials
Julia Marsh(Founder)Leland Maschmeyer(Founder)Matt Mayes(Founder)
Co-investorsAlante CapitalBAM VenturesDesigner FundHelmNew Earth VenturesScout Fund+7 more
Co-investorsIn-Q-TelM VenturesTGVPTransLink Capital
Transparent Path builds a cloud and IoT-based supply chain platform that uses continuous sensor data, machine vision, edge computing, and machine learning to improve traceability, reduce waste, and manage risk in the perishable food supply chain.
CleantechFoodTechHardwareIoTLogistics & Supply ChainSeattle, US
Mark Kammerer(Chief Executive Officer)inEric Weaver(Founder • Advisor, EMEA)in
UNSPACE develops engineering and technology solutions focused on sustainable innovation, including robotics, materials science, machine learning optimization, and rail automation systems.
Advanced ManufacturingDeep TechRoboticsSector Agnostic
Ben Peters(Project Manager & Founder)
Windscape develops AI-based software solutions that use onboard turbine and external data to improve the operational efficiency, smoothness, and predictability of wind farms.
AI & Machine LearningCleantechEnergy
Jason Yosinski(Cofounder / CEO)inEric Thompson(Cofounder / CCO)
Co-investorsIdeashipThird Derivative
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.























































































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