/Investor DB

Madrona Venture Group — 2021 Investments

23 investments dated 2021 · listed companies and verified rows first · show all

Nautilus Biotechnologynautilus.bioin𝕏NASDAQ: NAUTJun 2021

Nautilus develops proteomics technology to unlock the complexity of the human proteome for biomedical research and diagnostics.

BiotechDeep TechMedical DevicesSeattle, US

Sujal Patel(Founder)inParag Mallick(Founder)inMelissa Epperly(Director)inNicholas Nelson(Executive Officer)Subra Sankar(Executive Officer)inMatthew Murphy(Executive Officer)in

Co-investorsAndreessen HorowitzDefy PartnersAME Cloud Ventures

Spotnanaspotnana.comin𝕏Jul 2021✓ verified

Spotnana builds a Travel-as-a-Service platform that modernizes corporate travel purchasing, booking, and management for global enterprises by connecting them with travel providers through a unified technology stack.

Cloud ComputingEnterprise SoftwareSaaSTravel & HospitalityNew York, US

Sarosh Waghmar(Founder)inSteve Singh(Executive Chairman & CEO)inShikhar Agarwal(Founder)inS. Steven Singh(Executive Officer, Director)Frank Pelzer(Executive Officer)

BoardGreg Stanger(Director)in

Co-investors8VCBlank VenturesDecibel PartnersICONIQAmerican Express Ventures (Amex)Crosslink Capital+3 more

A-Alpha Bioaalphabio.comin𝕏Sep 2021

A-Alpha Bio uses synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions for pharmaceutical discovery and development.

AI & Machine LearningBiotechDeep TechSeattle, US

David Younger, PhD(Chief Executive Officer & Co-Founder)Randolph Lopez, PhD(Chief Technology Officer & Co-Founder)David Younger(Founder)inRandolph Lopez(Founder)in

Board seatMatthew S. McIlwain· per SEC Form D

Co-investorsAngel Collective Opportunity FundBreakout VenturesFarvatn VentureLux CapitalPlanet 9 CapitalBoom Capital+2 more

Knockknock.appin𝕏Series A · Feb 2021 · $10M

Knock is an AI-native customer engagement platform that lets teams build and send product, marketing, and transactional messaging across email, SMS, push, chat, and in-app channels from one place.

Cloud ComputingDeveloper ToolsMarketing TechSaaSSeattle, US

Thomas Petry(Executive Officer, Director, Promoter)Demetri Themelis(Executive Officer, Director, Promoter)

Board seatScott Jacobson· per SEC Form D

Co-investorsAfore CapitalCraft VenturesExpaSunflower Capital Management FundWhoa I Lp, By: Whoa VenturesWorklife Ventures+9 more

Outreachoutreach.aiin𝕏Jun 2021SEC filingmedium confidence

Outreach is a sales engagement platform, founded in 2014, that helps sales teams manage customer outreach and improve revenue outcomes.

AI & Machine LearningEnterprise SoftwareMarketing TechSaaSSales TechSeattle, US

Manny Medina(Founder)inManuel Medina(Founder)Wesley Hather(Executive Officer, Director)Andrew Kinzer(Founder)inGordon Hempton(Founder)inWes Hather(Founder)in

Board seatKaran Mehandru· per SEC Form D · $201M raise · filed Jun 2021

Co-investorsDFJSalesforce VenturesSands Capital Ventures408 VenturesAliya Capital PartnersBonfire Ventures+20 more

Trooptrooptravel.cominNov 2021acquired by Spotnana · Aug 2026

TROOP provides a meeting planning platform that helps remote and distributed teams research, compare, and select destinations for in-person meetings, and manage the entire logistics, attendees, and budgets for those gatherings.

SaaSTravel & HospitalityBrooklyn, US

Dennis Vilovic(Founder)inFelix Tabary(Executive Officer, Director)Sebastien Jarquin(Executive Officer, Director)Leonard Cremer(Founder)

BoardWendy Xiao Schadeck(Director)Matthew Osman(Director)

Board seatSteve Singh· per SEC Form D

Co-investorsAcurio VenturesEPIC VENTURESPlug and Play VenturesConexo Ventures

Amperityamperity.comSeries A · Jul 2021 · $100M

Amperity provides a customer data foundation that unifies fragmented customer data into a single source of truth, giving marketing and analytics teams and AI agents a complete view of each customer.

AI & Machine LearningData & InfrastructureMarketing TechSeattle, US

Derek Slager(Founder)Kabir Shahani(Founder)inAmy Pelly(Executive Officer)in

BoardMatt McIlwain(Director)Rajeev Singh(Director)Kelly Wright(Director)

Co-investorsDeclaration PartnersFoundation CapitalFUSEGeneral CatalystGreycroftHighsage Ventures+4 more

Battlesnakebattlesnake.comSep 2021 · $1.5M

Battlesnake is a competitive programming game where developers write code to control AI-powered snakes that compete against each other in automated leaderboards.

Developer ToolsGaming

Brad Van Vugt(Founder)Chris Hoefgen(Founder)Noah Warder(Founder)

Co-investorsAscend Venture CapitalAscend

Codacoda.ioin𝕏Jul 2021acquired by Grammarly · Dec 2024

Coda (now Superhuman Docs) is a collaborative workspace platform that combines document editing, database tables, and application-building capabilities for teams.

AI & Machine LearningEnterprise SoftwareFuture of WorkSaaSMountain View, US

Shishir Mehrotra(Founder)inAlex DeNeui(Founder)inLane Shackleton(Chief Product Officer)in

BoardReid Hoffman(Board Member (Greylock Partner; LinkedIn Co-Founder))inHemant Taneja(Board Member (General Catalyst))in

Co-investorsArba LLCDria VenturesGeneral CatalystGeneral PartnershipGreylock PartnersHomebrew+15 more

Common Roomcommonroom.ioin𝕏Mar 2021acquired by Zoom

Common Room is an AI-powered go-to-market platform that unifies first-party customer data with real-world buyer signals to provide buyer intelligence and automated action capabilities.

AI & Machine LearningMarketing TechSaaSSales TechSeattle, US

Viraj Mody(Founder)inTom Kleinpeter(Founder)inLinda Lian(Founder)inFrancis Luu(Founder)inKaren Ng(VP of Product)inJake Randall(Chief Operating Officer)in

Co-investors01 AdvisorsBlue Cloud VenturesGreylock PartnersIndex VenturesNext Play VenturesOperator Collective

Doorstead Risk-Adjacentdoorstead.comin𝕏Series A · Apr 2021 · $13M

Doorstead provides property management services, aiming to reduce vacancies by ensuring consistent tenant placement across homes.

PropTechSaaS

Jennifer Bronzo(Founder)inBernard Liang(Founder)inRyan Waliany(Founder)

Co-investorsAurum Venture PartnersAvanta VenturesHustle FundMetaPropMetaProp VenturesSilicon Valley Data Capital+5 more

Envisagenicsenvisagenics.cominSep 2021

Envisagenics uses AI-driven analysis of RNA splicing to discover novel drug targets for immuno-oncology and neurodegenerative diseases.

AI & Machine LearningBiotechMedical DevicesNew York, US

Martin Akerman, PhD(CEO & Co-founder)Martin Akerman(Founder)inMaria Luisa Pineda(Founder)in

Co-investorsDolby Family VenturesDynamk CapitalHAWKTAILM12 (Microsoft's Venture Fund)Red Cell IncubationThird Kind Venture Capital

Game Joltgamejolt.comAug 2021 · $2.6M

Creator-focused gaming community and social media platform for Gen Z gamers across web, desktop and mobile.

Seattle, US

David DeCarmine(Founder)Yaprak DeCarmine(Founder)in

Co-investorsAcequia Capital (AceCap)Graph Ventures

Magnifymagnify.ioinOct 2021

Magnify provides customer experience software for software companies, using AI and automation to deliver personalized customer interactions at scale.

AI & Machine LearningEnterprise SoftwareMarketing TechSaaSSeattle, US

Joshua Crossman(Founder)Josh Crossman(Founder)

BoardSudhir Steven Singh(Director)Barry Crist(Director)

Co-investorsDecibel PartnersOregon Venture FundBackedPivotal VenturesTechstars

Magnifytrymagnify.aiDec 2021 · $6M

New York City, US

Co-investorsTechstarsDecibel PartnersPivotal Ventures

Modulus Therapeuticsmodulustherapeutics.comSeed · Jul 2021 · $4Macquired by Ginkgo Bioworks · Apr 2024

Modulus Therapeutics was a Seattle biotech spun out of the Allen Institute for AI that used machine learning to engineer immune cells, initially NK cells for cancer, later shifting toward autoimmune cell therapies.

BiotechSeattle, US

Bryce R Daines(Executive Officer, Director)Max C Darnell(Executive Officer, Director)

Co-investorsKdT Ventures

OctoAIocto.ai𝕏Nov 2021acquired by NVIDIA · Sep 2024

The page is NVIDIA's site (octo.ai now redirects to NVIDIA content), presenting AI computing platforms, GPU hardware, and related tools for developers, researchers, and industries such as media, manufacturing, healthcare, and supply chains.

AI & Machine LearningCloud ComputingHardwareSanta Clara, US

Jason Knight(Founder)Jared Roesch(Founder)Thierry Moreau(Founder)Tianqi Chen(Founder)

BoardLuis Ceze(Founder)inMatt McIlwain(Director)

Co-investorsAmplify PartnersMadrona Venture LabsAdditionTiger Global Management

Spice AIspice.aiin𝕏Oct 2021 · $1M

Spice AI provides a unified data and AI engine that enables developers to build AI-driven applications without requiring specialized expertise in data science or machine learning.

AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSeattle, US

Luke Kim(Founder)inLane Harris(Co-Founder & VP of Engineering)inPhillip LeBlanc(Founder)in

Co-investorsAlumni VenturesAsymmetricBasis Set VenturesBlackbird VenturesCardinia VenturesGeek Ventures+8 more

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Booster FuelsOzette Technologies, Inc.Zeitworks TechnologiesKiwi GroceryPluto Vr

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.