CALIFORNIA INNOVATION — Full Portfolio

Miist develops inhaled microparticle therapeutics that deliver medicine to the bloodstream in 30 seconds, targeting conditions like migraine, pain, and anxiety where rapid onset is critical.

BiotechDigital HealthHealthtechMedical DevicesAlameda, US

EEEric Ezerins(Cofounder, Head of Technology)inDSDalton Signor(Cofounder, CEO)inRandy Krebs(Executive Officer)JSJeffrey Schuster(Chief Technology Officer)inEvan Alfano(Director)

Co-investorsENEntrepreneur FirstFRFREEFLOWTHThe Innovation SpaceRERefactor Capital

CatenaBio develops precision conjugation technology using native amino acids to enable biotherapeutic fusions of small molecules, nucleic acids, enzymes, and cells.

BiotechDeep TechHealthtechMedical DevicesBerkeley, US

MLMarco Lobba(Founder)inMatthew Francis(Founder)inMLMarco Lobba, Ph.D.(Founder)in

Co-investorsCICivilization Ventures Management, LlcCRCreative Destruction Lab (CDL)FRFREEFLOWIAIaso VenturesJUJude GomilaLOLongeVC+13 more

Cooler Heads develops scalp cooling technology to prevent hair loss in cancer patients undergoing chemotherapy.

HealthtechMedical DevicesSan Diego, US

KDKate Dilligan(Founder & CEO)in

BoardMGMaria Gonzalez-Blanch(Director)inMSMICHAEL SCHOTZINGER(Director)inLIZ TODIA(Director)LZLIZ ZAMBORY(Director)inJPJASON PESTERFIELD(Director)in

Co-investorsADAd Astra VenturesALAloft VCASAstiaGOGolden SeedsMUMutual Capital PartnersNUNuFund Venture Group+2 more

A Berkeley spinout developing a new generation of medicines for the brain and other hard-to-treat tissues using breakthrough science from UC Berkeley and the Innovative Genomics Institute.

BiotechBerkeley, US

Ross Wilson(Executive Officer, Director, Promoter)DFDana Foss(Executive Officer, Director, Promoter)in

BoardJaromir Tesar(Director)

EdVisorly is an AI-based enrollment platform for higher education institutions, used to manage admissions and enrollment operations.

AI & Machine LearningEdTechSaaS

MSManny S.(Founder)inMSManny Smith(Founder & CEO)CWChristine Wyatt(Chief Operating Officer)inLLLandon Lewis(Chief Technology Officer)in

Co-investorsDODorm RoomMOMotley Fool VenturesPOPotencia VenturesSISilicon ValleyBLBlack Operator

Eko develops FDA-cleared digital stethoscopes and AI-powered software that enables healthcare professionals to detect and diagnose cardiovascular disease with greater accuracy.

AI & Machine LearningDigital HealthHealthtechMedical Devices

CLConnor Landgraf(Co-Founder and CEO)inTCTyler CrouchinJBJason Bellet(Co-Founder and Chief Business Officer)in

Co-investorsQUQuesta CapitalHIHighland Capital PartnersARArtis VenturesBEBetter Ventures Central LlcDIDigiTx Partners LLCEVEvolution VC Partners+13 more

Encellin develops next-generation therapies for patients with chronic unmet clinical needs, using technology originating from Dr.

BiotechDeep TechHealthtechMedical DevicesSan Francisco, US

TDTejal Desai(Technology Expert, Founder)RMRonald Martell(Strategic Advisor, Founder)inCNCrystal Nyitray(Executive Officer, Director, Promoter)inGWGrace Wei(Executive Officer, Director, Promoter)in

BoardMaria del Consuelo Valverde(Director)

Co-investorsENEndurance28EVEvolution VC PartnersHOHow Women InvestITITERATIVEMEMetaplanetSASand Hill Angels+4 more

EngageBio develops DNA-based medicines using proprietary non-viral delivery technology to achieve extended therapeutic expression from a single dose with low manufacturing complexity.

BiotechDigital HealthHealthtechSan Francisco, US

WOWill Olsen(Founder)in

Co-investorsMEMetaplanetSCSciFoundersVEVentureSouqWOWorldQuant VenturesY Y Combinator1010X Capital+8 more

Android for EV charging - software solution that works with any 3rd party hardware

CleantechEnergyMobility & TransportationSan Leandro, US

Arcady Sosinov(Executive Officer, Director)

BoardChad Bown(Director)Michael Mahan(Director)Richard Steele(Director)Gary Moskovitz(Director)

Co-investorsALAlumni VenturesBLBlue Bear Capital PartnersFOFoothill VenturesMAMarketX VenturesMOMomenta VenturesSTStanley Ventures+9 more

GC AI is an AI platform built for corporate in-house legal teams, letting lawyers draft, review, and analyze legal documents, research case law, and run contract-review workflows.

AI & Machine LearningLegalTechSaaSSan Mateo, US

CZCecilia Ziniti(Co-Founder & CEO)inBPBardia Pourvakil(Co-founder & CTO)in

Co-investorsAZAZURO CAPITAL VENTURESFEFellowsFJFJ LabsNONorthzoneSCScale Venture PartnersTETech Square Ventures+3 more

Kyte was an on-demand car rental startup that delivered and picked up rental vehicles at customers' locations, aiming eventually to support teleoperated and autonomous vehicle delivery.

Co-investorsAMAmplo VenturesFJFJ LabsFLFlucas VenturesFUFundersClubRORosecliff Ventures

LILT provides a multilingual AI platform that uses agentic AI models combined with expert human verification to translate and localize enterprise content such as product materials, technical documentation, and marketing campaigns.

AI & Machine LearningEnterprise SoftwareSaaSSan Francisco, US

JDJohn DeNero(Director)inSGSpence Green(Executive Officer, Director)in

BoardWilliam Coughran(Director)MRMark Rostick(Director)in

Co-investorsCLClear VenturesINIn-Q-TelINIntel CapitalKUKube VCRERedpoint VenturesSESequoia Capital+2 more

Mammoth Bio develops technology to read and write the code of life, operating in the biotechnology sector.

BiotechDeep TechMedical DevicesBrisbane, US

JDJennifer Doudna(Founder)inTMTrevor Martin(Co-founder, Chief Executive Officer)inJCJanice Chen(Co-founder, Chief Scientific Officer & President, Research)inLHLucas Harrington(Co-founder)inATAshley Tehranchi(Executive Officer, Director)in

BoardUrshit Parikh(Director)

Co-investors8V8VCBEBerkeley FrontierDEDecheng CapitalFOForesite CapitalMAMayfield FundMIMission Bay Capital+10 more

Modelwise develops Paitron, software that automates safety analysis such as FMEA for critical hardware systems using model-based failure propagation, AI, and qualitative models.

AI & Machine LearningDeep TechSaaS

Co-investorsATAtlas Ventures (UK)EMEmerging Ventures

Prosper operates an online lending marketplace connecting borrowers with investors, offering personal loans up to $50,000 (issued by WebBank), a credit card, and investment products that let individuals invest in consumer loans.

FintechMarketplacesSan Francisco, US

DKDavid Kimball(CEO)in

Co-investorsAKAkkadian VenturesBRBreyer CapitalEMEmergence Capital PartnersF-F-Prime CapitalFEFenway Summer VenturesFRFrancisco Partners+8 more

Resemble develops generative voice models and synthetic speech technology, alongside deepfake detection capabilities.

AI & Machine LearningCybersecurityDeep TechEnterprise SoftwareMedia & Entertainment

ZAZohaib Ahmed(Co-founder)inSMSaqib Muhammad(Co-founder)in

Co-investorsBEBerkeley FrontierBEBetaworksBRBright Pixel CapitalCOComcast VenturesGLGlobal BrainGMGMG Ventures+12 more

Sequin offers a debit card and financial product aimed at women, with a focus on building credit and financial education.

ConsumerFintech

VGVrinda Gupta(Founder)in

Co-investorsDODorm RoomEMEmles Venture PartnersFIFirst Check VenturesSCScout FundSCScribble VenturesABAbstract Ventures+9 more

SixMap provides a cyber defense platform that discovers digital assets across IPv4 and IPv6 using its 6Gen computational mapping algorithm and continuously scans all ports on each host to identify exposures.

AI & Machine LearningCybersecurityEnterprise SoftwarePasadena, US

JKJason Kaplan(Chief Executive Officer)inGregory Levesque(Director)AMAustin Murdock(Chairman, Chief Scientist, and Founder)inWilliam Jr. Murdock(Executive Officer, Director)

BoardRARobert Ackerman(Director)inMJMichael Janke(Director)in

Co-investorsDADataTribeIAIAG Capital Partners

Space Kinetic develops technology to enable frequent, low-cost maneuvering and operations for spacecraft and space systems.

Deep TechHardwareSpace Tech

SZScott Ziegler(Founder)in

Co-investorsBABackswing VenturesBABalerion Space VenturesINIndustrious VenturesUPUP PartnersCECerraCap Ventures

Stylus Medicine develops in vivo genetic medicines using engineered recombinases, with initial focus on creating CAR-T therapies delivered via lipid nanoparticles for oncology, autoimmune, and genetic diseases.

BiotechDigital HealthMedical Devices

Michael C. Bassik, Ph.D.(Scientific Founder)ENEmile Nuwaysir, Ph.D.(Chairman & Chief Executive Officer)inJFJason Fontenot, Ph.D.(Chief Scientific Officer)

Co-investorsBRBrainstorm VenturesKHKhosla VenturesNENeva Sgr.RARA CapitalTATachyon VenturesABAbbVie

Synvivia engineers molecules designed to reprogram cells.

AI & Machine LearningBiotechHealthtechSan Francisco, US

GLGabriel Lopez(Founder/CEO)in

Co-investorsCRCreative VenturesMEMetaplanetTHThundermark CapitalY Y CombinatorFOFor Good VenturesLILightspeed Venture Partners+2 more

TransCrypts is a blockchain-based platform for verifying and sharing employment, health and educational credentials.

CybersecurityData & InfrastructureFintechNewark, US

ZZZain Zaidi(Founder)inZain Z(Founder)

Co-investorsALAlpha EdisonALAlumni VenturesATAtland VenturesBEBeyond CapitalFAFactionINInformed Ventures Advisors, Llc+10 more

Windfall is a people intelligence and AI company that provides access to people data along with propensity modeling and machine learning to help go-to-market teams prioritize resources and engage the right prospects.

AI & Machine LearningData & InfrastructureSaaSSales Tech

ABArup Banerjee(Founder)inDaniel Stevens(Founder)in

Co-investorsBUBullpen CapitalBOBonfire VenturesGRGreat Oaks Venture CapitalVAValuestream VenturesFOFortress Investment GroupKOKohala Ventures

Your360 AI runs interview-based 360-degree feedback programs where an AI coach conducts voice conversations with employees and their feedback providers, then synthesizes the results into coaching themes and a prioritized growth plan.

AI & Machine LearningFuture of WorkHR TechSan Francisco, US

Jared Seth Goralnick(Executive Officer, Director, Promoter)SKSergio Kaszczyszyn(Executive Officer, Director, Promoter)inRenata Elisabeth Bell(Executive Officer, Director, Promoter)

Co-investorsCACapital Factory