Chamber Cardio

Chamber Cardio, which operates as "Chamber," builds technology and operational infrastructure that supports cardiologists and health plans in managing patients with cardiovascular disease under value-based care arrangements. The company's platform aggregates cardiology signals, workflows and patient context, integrates directly with practices' electronic health records, and applies workflow-native AI to prioritize high-risk patients, identify gaps in guideline-directed therapy and reduce manual chart review. Alongside the software, Chamber supplies dedicated care teams that act as an extension of practices, plus value-based contracting support, analytics, evidence-based guidance and local physician networking that connects cardiologists with primary care referral sources.

The company describes a dual-sided model that serves cardiologists, patients and payers simultaneously: practices receive additive support and are rewarded for outcomes, patients are intended to experience more timely and coordinated care with fewer gaps, and payers gain clearer visibility into cardiovascular performance and total cost of care while benefiting from reduced hospital utilization. Chamber states it does not acquire practices, instead bringing them into a network through partnerships and wrapping care teams and technology around them. Reported outcome categories on its site include decreases in total inpatient admissions, CHF-related admissions and emergency room admissions, and reductions in total cost of care for congestive heart failure patients.

Founding story

Chamber was co-founded by George Aloth, a former Blue Cross Blue Shield health plan president and CEO and value-based kidney care executive who was group president at Somatus and previously performed compliance and performance reviews of Medicare health plans as a CMS contractor; Sameer Sheth, M.D., a board-certified cardiologist who practiced at Massachusetts General Hospital and served in clinical leadership roles at CareMore, RubiconMD and Oak Street Health; and Jeffrey De Flavio, M.D., co-founder of Pearl Health and founding CEO of Groups Recover Together. Aloth has said cardiology was the top expense affecting his health plan membership with few available solutions, and that he and Sheth combined payer and clinical perspectives to start the company in September 2022.

Business model

Chamber partners with both health plans and cardiology practices to operate value-based care programs for cardiovascular disease. It builds networks of independent cardiologists rather than acquiring practices, supplying a proprietary population health platform, care teams and contracting and operational support. The company frames its economics around converting improved outcomes and avoided utilization into savings that fund providers.

Value-based arrangements with payers and cardiology practices: Chamber supports value-based contracts in which improved coordination and outcomes generate savings, with those savings flowing back to fund provider care.

Traction

As of February 2026 Chamber reported multiple payer partnerships and a network of more than 500 cardiologists across seven states, including several large national Medicare Advantage payers plus Blue Cross Blue Shield and other regional plans. Cumulative funding was reported at $69.5 million. Announced partnerships include Pearl Health (2024) and Humana for Medicare Advantage members (2026).

Latest developments

In February 2026 Chamber closed a $60 million Series A led by Frist Cressey Ventures, with General Catalyst, AlleyCorp, American Family Ventures, Company Ventures, Optum Ventures, Healthworx Ventures and Black Opal Ventures participating and debt from HSBC Innovation Banking; proceeds are earmarked for new markets, expanded payer and practice partnerships, care team growth and further AI investment. In March 2026 the company announced a value-based cardiology partnership with Humana for Medicare Advantage members. Management also points to emerging CMS and CMMI specialist-focused programs, including the LEAD and ACCESS models, as tailwinds.