/Investor DB

Palo Santo VC — Full Portfolio

30 tracked investments · listed companies and verified rows first

2A Biosciences2abiosci.comin𝕏

2AB BioscienceS develops first-in-class small molecule therapeutics targeting the 5-HT2A receptor for ophthalmology and central nervous system disorders.

BiotechDeep TechDigital HealthEdTechHealthtechMedical DevicesSanta Monica, US

Alex Speiser(Co-Founder & Chief Executive Officer)inCharles Nichols, PhD(Co-Founder & Chief Science Officer)David Nichols, PhD(Co-Founder & Head of Chemistry)Tim Foster, PhD(Co-Founder & Head of Translational Discovery)

BoardGopal Das(Director)

Co-investorsLIONHEART VENTURESWhat If Ventures

Beckley Psytechbeckleypsytech.com

AtaiBeckley develops rapid-acting and durable mental health treatments for patients with difficult-to-treat mental health conditions.

BiotechMedical DevicesMental Health

Christian AngermayerCosmo Feilding Mellen(Founder)inSrinivas Rao

Co-investorsFJ LabsIter InvestmentsLeafy TunnelNoeticRedbus VenturesWhat If Ventures+1 more

BRC Therapeuticsbrctherapeutics.comin

BRC Therapeutics develops and manufactures botanically-derived pharmaceutical products, with expertise spanning drug development and manufacturing for pharmaceutical applications.

BiotechDigital HealthHealthtechMedical Devices

George Hodgin(Founder and CEO)inCharles Schumacher

Co-investorsDelta Emerald Ventures

bright-mindsbrightmindsbio.com𝕏

Bright Minds Biosciences develops selective serotonin receptor agonists (5-HT2A and 5-HT2C) without 5-HT2B activity, built on a proprietary chemistry platform.

BiotechDeep TechHealthtechNew York, US

Alan Kozikowski(Executive Officer, Director)inIan McDonaldRyan Cheung(Chief Financial Officer)JAN PEDERSEN(Chief Science Officer)Gideon Shapiro(Executive Officer)Revati Sheeniwas(Executive Officer)

Co-investorsLifeSci Venture PartnersPsyMed Ventures

Delixdelixtherapeutics.cominSep 2021 · $70M

Delix Therapeutics develops third-generation, non-hallucinogenic neuroplastogens for people with neurological conditions, using a discovery platform to identify novel compounds.

BiotechDigital HealthMedical Devices

Co-investorsArtis VenturesCasa Verde CapitalDolby Family VenturesNoeticOMX VenturesPsyMed Ventures+6 more

Diamond Therapeuticsdiamondthera.comin

Diamond Therapeutics is a preclinical biotechnology company developing drug treatments for psychiatric and neurological disorders, with a focus on the pharmacology and therapeutic use of psychedelic compounds.

BiotechHealthtechMental HealthToronto, CA

Judy Blumstock(Chief Executive Officer, Founder, Director)inMichael B. McDonnell(Chief Medical Officer)Grant McCutcheon(Chief Financial Officer)in

Co-investorsJLSNoeticNew Enterprise Associates (NEA)Nextech InvestRA Capital

Fauna Biofaunabio.comin

Fauna Bio applies AI and computational analysis to its proprietary biobank of data from extreme mammals such as hibernating species to identify drug targets that are conserved across species including humans.

AI & Machine LearningBiotechDeep TechHealthtechEmeryville, US

Linda Goodman(Founder)inAshley(CEO)

Co-investorsage1Farvatn VentureGRIDS CapitalLifeforce CapitalMetaplanetVibe Capital+4 more

Gilgamesh Pharmaceuticalsgilgameshpharmaceutical.comin𝕏Seed · Dec 2022 · $39M

Gilgamesh Pharmaceutical develops novel chemical entities for psychiatric disorders using medicinal chemistry and AI-powered translational platforms to design rapid-acting therapies targeting neurobiological mechanisms rather than symptom management.

AI & Machine LearningBiotechDigital HealthHealthtechNew York City, US

Jonathan Sporn(Founder)inAndrew Kruegel(Founder)inDalibor Sames(Founder)inJONATHAN SPORN(Founder)inAndrew Kruegel, Ph.D.(Executive Officer)Jonathan Sporn, M.D.(President and Chief Executive Officer)in

Co-investorsAera VCFrontera Technology VenturesFrontier Path VCJames Beshara FundJLSMagnetic Ventures+25 more

Journey Clinicaljourneyclinical.comin𝕏Sep 2021 · $3M

Journey Clinical provides ketamine-assisted psychotherapy (KAP) for depression, anxiety, and PTSD, partnering patients with licensed therapists and medical teams while coordinating with major insurance providers.

Digital HealthMedical DevicesMental Health

Jonathan Sabbagh(Co-founder & Executive Chairman of the Board)inMyriam Barthes(Co-founder & CEO)in

Co-investorsAble PartnersAlleyCorpCoalition OperatorsFifty YearsMantis CapitalPROOF+8 more

Kadence Biokadencebio.com

Kadence Bio is a clinical-stage life sciences company developing therapeutics for conditions in sexual and mental health.

BiotechDigital HealthMental Health

Ksana Healthksanahealth.comin

Active seed-stage healthcare company

Eugene, US

Nicholas Allen(Chief Executive Officer)Phillip Scripa(Chief Financial Officer and Secretary)William Shortt(Chief Operating Officer)Jan Hardorp(Director)in

Co-investorsBIP VenturesJLSre.Mind Capital

Modulate Biomodulatebio.comin

Modulate Bio develops small-molecule GABAA positive allosteric modulators to treat neurological disorders including Essential Tremor, epilepsy, and anxiety.

BiotechDeep TechHealthtechAllston, US

Dario Doller(Co-founder)inKevin Hodgetts(Founding Lab / Co-founder)inAndrew Thomson(Executive Officer, Director, Promoter)in

Co-investorsPillar VCHealthspan Capital

MycoMedicamycomedica.comin

MycoMedica Life Sciences is a biopharmaceutical company developing psilocybin-based treatments for mental health and neurodegenerative disorders.

BiotechDigital HealthMental HealthShelton, US

Co-investorsLauder PartnersObvious Ventures

Pangea Biopangeabio.comin

Pangea Bio develops therapies targeting central nervous system and mental health disorders by activating the TrkB receptor pathway to promote neuronal survival and synaptic plasticity.

BiotechDeep TechDigital Health

Co-investorsMetaplanetNO LABEL VENTURESSeaside VenturesVox CapitalXEIA Venture Partners

Reunion Neurosciencereunionneuro.comin𝕏Jan 2024

Reunion Neuroscience is a clinical-stage biopharmaceutical company developing serotonergic psychedelic therapies for mental health conditions such as postpartum depression, adjustment disorder, and generalized anxiety disorder.

BiotechDigital HealthMental HealthMorristown, US

Sahil V. Kirpekar(President and CEO)inGregory Mayes(Executive Officer, Director)Ellen Lubman(Director)Mark Pollack(Executive Officer)inNathan Bryson(Executive Officer)inMark Theeuwes(Executive Officer)in

Co-investorsFemHealth VenturesMitsui Global InvestmentMPM BioImpactNovo Holdings

Sensorium Therapeuticssensorium.bioinJul 2021

Sensorium Therapeutics is a clinical-stage biotech company developing novel CNS therapies for anxiety, epilepsy, and cognitive dysfunction using its SensAI platform, which integrates AI, chemistry, and curated natural product data to identify therapeutic patterns from over 50 million biological relationships.

AI & Machine LearningBiotechDigital HealthMedford, US

Jerrold Rosenbaum(Director)inJacob Hooker(Executive Officer, Director)inPranav Tadi(Executive Officer)

BoardRyan Katz(Director)inKevin Lalande(Director)inRichard Simon(Director)

Co-investorsBonaventure Equity, LLCHatteras Venture PartnersIter InvestmentsMission BiocapitalRoute 66 VenturesService Provider Capital+2 more

Syndeio Biosciencessyndeio.bioin

Syndeio Biosciences is a synapse-focused biotech developing precision neurotherapeutics for neuropsychiatric, mental health, and cognitive disorders such as depression and Alzheimer's.

AI & Machine LearningBiotechDigital Health

Co-investorsEvolution VC PartnersTenmileCatalio Capital Management

Tactogentactogen.comin𝕏

Tactogen develops patented new chemical entities, including benzofuran-based compositions, and conducts preclinical research and publishes data on these compounds.

BiotechDeep TechHealthtech

Matthew Baggott(CEO)in

Co-investorsLeafy TunnelNoeticPsyMed Ventures10X CapitalWefunder

Transcend Therapeuticstranscendtherapeutics.comin

Transcend Therapeutics develops rapid-acting pharmaceutical treatments for neuropsychiatric diseases, including PTSD and depression, targeting patients unresponsive to current psychiatric medications.

BiotechDigital HealthMedical DevicesMental Health

Blake Mandell(Co-Founder & CEO)in

Co-investorsAlleyCorpAlpha Wave GlobalEmerald Development ManagersAlley Robotics Ventures

Wavepathswavepaths.comin𝕏Oct 2021 · $4.5M

Wavepaths develops adaptive therapeutic music designed to support mental health and wellness practitioners in their sessions.

Digital HealthMental HealthWellness & Fitness

Mendel Kaelen(Founder & CEO)in

Co-investorsMITONReflex CapitalLIONHEART VENTURESNeo Kuma Ventures

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

<UNKNOWNatai Life SciencesBeacon BiosignalsBionomicsBlackbox BioCybinFluenceneurocarePsy TherapeuticsXylo

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.