Union Square Ventures (USV) — 2022 Investments
20 investments dated 2022 · listed companies and verified rows first · show all
Blackbird Laboratories is a nonprofit life sciences incubator that translates university research breakthroughs into venture-ready biotech companies focused on developing new medicines and enabling technologies.
BiotechDeep TechBaltimore, US
Ben Leventhal(Executive Officer, Director)inMatt Tremblay, PhD(Chief Executive Officer)inEddie Cherok, PhD(Chief Business Officer)in
BoardMo Koyfman(Director)inMarguerite Mariscal(Director)
Board seatFred Wilson· per SEC Form D
Co-investorsUniversity System of Maryland Momentum FundAmex VenturesAndreessen HorowitzBrooks ReitzCircle VenturesCoinbase Ventures+6 more
Thomson Reuters is a content and technology company providing AI-powered tools and information services—including CoCounsel and ONESOURCE—for legal, tax, accounting, risk, fraud, and government professionals.
AI & Machine LearningEnterprise SoftwareLegalTechSan Francisco, US
Jake Heller(CEO)inSteve Hasker(President and Chief Executive Officer)inLaura Safdie(Founder)Pablo Arredondo(Founder)Joanna Hueyr w(CTO)
Board seatJohn Buttrick· per SEC Form D
Co-investors8VCAccess Venture PartnersAllen Institute for AI (AI2) IncubatorBoxGroupBuildGroupCanvas Ventures+24 more
Shift EV converts commercial vehicle fleets to electric by retrofitting existing vehicles with battery packs and electric powertrains.
Advanced ManufacturingCleantechClimate TechLogistics & Supply ChainMobility & TransportationBoston, US
Aly Eltayeb(Executive Officer, Director)in
Board seatAlbert Wenger· per SEC Form D
Co-investorsAlgebra VenturesWamda Capital
Zerion is a self-custodial, multichain wallet and data platform that aggregates assets and positions across 58+ blockchains in real time, offering swap routing, trading, and an API for wallet data access.
Crypto & Web3Data & InfrastructureFintechSan Francisco, US
Evgeny Yurtaev(Founder & CEO)inAlex Bashlykov(Director)in
BoardToby Coppel(Director)inVadim Koleoshkin(Director)in
Board seatBrad Burnham· per SEC Form D · $15M raise · filed Aug 2022
Co-investorsAlliance DAO (ex DeFi Alliance)BitDAOBlockchain CoinvestorsDe Fi Alliance HoldingsDigital Currency GroupG1 Ventures+18 more
Alife Health develops artificial intelligence technology to modernize and personalize the in vitro fertilization (IVF) process for fertility clinics and patients.
AI & Machine LearningDigital HealthHealthtechMedical Devices
Paxton Maeder-York(Founder)inMark Lown(Founder)
Co-investorsLux CapitalMaveronFarvatn VenturePlanet 9 CapitalIA VenturesSpringbank
Brave Health is a virtual mental healthcare provider offering telehealth therapy delivered by licensed providers across a growing number of U.S. states.
Digital HealthHealthtechMental HealthMiami, US
Anna Lindow(Founder)in
Co-investorsAble PartnersAloft VCAlpha PartnersAlumni VenturesBascom VenturesCity Light+7 more
CarbonChain provides software for companies and financial institutions to measure and account for greenhouse gas emissions across supply chains, from production to shipping to use of commodities and products.
Advanced ManufacturingClimate TechData & InfrastructureEnterprise SoftwareSaaSLondon, GB
Adam Hearne(Founder)inRoheet Shah(Founder)inROHEET SHAH(Founder)inArchy de Berker(Head of Data \u0026 Machine Learning)Jeremiah SmithYury Oparinin
Co-investorsAera VCBlackbird VenturesBragiel BrothersC3 VenturesMAVA VenturesPioneer+9 more
Jobbatical provides an automated visa and immigration compliance platform for HR teams managing international hires across 30+ countries.
Enterprise SoftwareFuture of WorkHR Tech
Karoli Hindriks(Founder)in
Co-investorsAirTree VenturesInventureInventureInveready Technology Investment GroupKarma VenturesLocalGlobe+5 more
Lithos Carbon uses enhanced weathering of basalt spread on croplands to remove atmospheric carbon dioxide and store it in ocean carbonates.
AgTechCircular EconomyCleantechClimate TechSeattle, US
Mary Yap(Founder)inNoah Planavsky(Founder)inChris Reinhard(Founder)inRob Hranac(Chief Operating Officer)inJake Schneider(Head of Research Commercialization)Elliot Chang(Head of Research Partnerships)in
Co-investorsBain Capital VenturesCarbon Removal PartnersCavallo VenturesFall Line CapitalGreylock PartnersKayak Ventures+1 more
Mindset is a daily wellness and self-care app featuring audio collections and stories from celebrities and experts.
ConsumerMental HealthWellness & FitnessKing Of Prussia, US
April J Perrymore(Executive Officer, Director, Promoter)Darlene Link(Executive Officer, Director, Promoter)
Co-investorsA.Capital Venturesalphabet angelsTq Ventures LlcBanana CapitalGold House VenturesKing River Capital+3 more
Ostrom provides a multilingual energy management platform that enables consumers to switch, monitor, and reduce their electricity consumption.
CleantechEnergyIoTSaaSBerlin, DE
Matthias(CEO)Karl(CMO/CPO)Karl Villanueva(Founder)Matthias Martensen(Founder)Matthias Martensen Karl Villanueva(Founder)
Co-investorsEneco VenturesJ12 VenturesSE Ventures468 CapitalAdjacent Ventures LlcProject Ventures
Polygon provides blockchain-based cross-border treasury settlement using stablecoins, letting institutions convert between US dollars and stablecoins, move funds onchain, and pay out over bank rails like SWIFT, ACH, and RTP.
Crypto & Web3Data & InfrastructureFintechHR Tech
Sandeep Nailwal(Founder)inAnurag Arjun(Founder)Jaynti Kanani(Founder)Mihailo Bjelic(Founder)
Co-investorsAlpha Wave GlobalCoinbase VenturesDePIN XDigital Currency GroupDragonflyDraper Associates+40 more
Primitives is a biodesign lab that develops advanced biomaterials—including biopolymers, biominerals, and compostable packaging—aimed at ecosystem regeneration and emissions reduction.
BiotechClimate TechNew Materials
Co-investorsThe E14 FundHarlem CapitalRedpoint VenturesStellation Capital
Reown provides an SDK for accepting cryptocurrency payments from multiple wallet types, exchanges, and fiat onramps through a single integration.
Crypto & Web3Data & InfrastructureDeveloper ToolsEnterprise SoftwareFintechSaaS
Co-investors1k(x)1kxCoinbase VenturesSC VenturesTriton CapitalConsenSys+10 more
Shortwave builds an AI-first communications app designed for effective human-AI collaboration, starting with email.
AI & Machine LearningEnterprise SoftwareFuture of WorkSaaSSan Francisco, US
Andrew Lee(Founder)inJonny Dimond(Founder)in
Co-investorsY CombinatorAfore CapitalFlybridge Capital PartnersLightspeed Venture PartnersConvective CapitalFounder Collective
SmartHop provides software tools for trucking fleet operators to manage load booking, dispatch, and operations across spot market and contract freight.
AI & Machine LearningLogistics & Supply ChainSaaSMiami, US
Guillermo Garcia(Founder)inMiguel Sucre(Founder)Joaquin Brillembourg(Founder)
Co-investorsAlumni VenturesEqual VenturesGreycroftSozo VenturesTechstarsTwo Culture Capital+3 more
Stadium Live is a gamified social sports platform aimed at younger sports and culture fans, combining sports content with interactive social and reward features.
ConsumerSocialSports Tech
Co-investors6th Man VenturesGolden VenturesIntonation VenturesMaple VCOriginsPosition Ventures+3 more
Super Payments operates a payment network offering merchants 0% processing fees and shoppers AI-powered checkout with rewards; the platform integrates open banking, cards, and buy-now-pay-later to facilitate UK online commerce.
E-commerceFintechSaaSLondon, GB
Samir Desai(Founder)inSamir Desai CBE(Founder)in
Co-investorsAccelLocalGlobePhoenix CourtCreandum
Web3Auth provides non-custodial authentication and key management to give users simple, secure access to digital assets and identity across multiple blockchain platforms and applications.
Crypto & Web3CybersecurityDeveloper Tools
Zhen Yu Yong(Founder)inLeonard Tan(Founder)
Co-investorsDigital StrategiesFenbushi CapitalIlluminati CapitalKyros VenturesMulticoin CapitalYBB Foundation+4 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.

















































































































