/Investor DB

Polaris Partners — 2022 Investments

13 investments dated 2022 · listed companies and verified rows first · show all

Camp4 Therapeutics CorpNASDAQ: CAMPJun 2022SEC filingmedium confidence

Camp4 Therapeutics develops antisense oligonucleotides targeting regulatory RNAs to increase gene expression and restore healthy protein levels for genetic diseases, with an initial focus on treating SYNGAP1-related developmental and epileptic encephalopathy.

BiotechCambridge, US

Richard Young(Director (Class II))Josh Mandel-Brehm(Chief Executive Officer and Director (Class III))in

BoardMICHAEL HIGGINS(Director)JORGE CONDE(Director)in

Board seatAmir Nashat· per SEC Form D · filed Jun 2022

Co-investors5AM VenturesAndreessen HorowitzLongwood Fund

Fractylfractyl.comin𝕏NASDAQ: GUTSJan 2022SEC filingmedium confidence

Fractyl develops therapies for obesity and type 2 diabetes, focusing on non-drug-based approaches rooted in understanding metabolic disease mechanisms.

BiotechHealthtechMedical DevicesLexington, US

Jay Caplan(Founder)inHarith Rajagopalan(Co-Founder and CEO)inLISA DAVIDSON(Executive Officer)inDiane Marcou(Executive Officer)in

BoardAllan Will(Director)inNimesh Shah(Director)in

Board seatAmy Schulman· per SEC Form D · $20.1M raise · filed Jan 2022

Co-investorsBessemer Venture PartnersCatalio Capital Management, LPEmergent Medical Partners, LLPGeneral CatalystMithril Capital ManagementDomain Associates+1 more

Agbiomeagbiome.comFeb 2022AcquiredSEC filingmedium confidence

US agricultural biotech that discovered microbe-based crop protection products; its assets were sold to Certis Biologicals and Ginkgo Bioworks in 2024.

AgTechResearch Triangle Park, US

Scott Uknes(Manager)inEric Ward(Manager)Paul Schulze-Lefert(President)Michael Koziel(Vice President and Manager)

BoardThomas Dietz(Manager)Kristina Burow(Manager)in

Board seatAmir Nashat· per SEC Form D · $117.2M raise · filed Feb 2022

Co-investorsAliment CapitalBlue Horizon CorporationPontifax AgTechARCH Venture PartnersBill & Melinda Gates FoundationLeaps by Bayer+1 more

Dewpoint Therapeuticsdewpointx.comin𝕏Series A · Feb 2022 · $60M

Dewpoint Therapeutics develops condensate-modulating drugs by using an integrated platform that maps, measures, and modulates biomolecular condensates to identify druggable targets and disease mechanisms.

AI & Machine LearningBiotechDeep TechBoston, US

Richard Young, Ph.D.(Director)inAnthony Hyman, Ph.D.(Director)Tony Hyman(Scientific Co-founder)Rick Young(Scientific Co-founder)Elisabeth Leiderman(Executive Officer)inIsaac Klein, M.D., Ph.D.(Executive Officer)

Board seatAmir Nashat· per SEC Form D

Co-investorsARCH Venture PartnersEcoR1 CapitalGeneral CatalystSamsara BioCapital6 Dimensions CapitalInnovation Endeavors+6 more

Faraday Pharmaceuticalsfaradaypharma.comOct 2022DefunctSEC filingmedium confidence

Seattle biotech that developed FDY-5301 for cardiac and skeletal muscle injury; ceased operations in February 2026.

BiotechSeattle, US

Mark Roth(Executive Officer, Director, Promoter)Brian Blackman(Executive Officer)Simon Tulloch(Executive Officer)Stephen Hill(Executive Officer, Director)

BoardPaulina Hill(Director)inSteven Gillis(Executive Officer, Director, Promoter)in

Board seatTerrance McGuire· per SEC Form D · $102.8M raise · filed Nov 2022

Co-investorsARCH Venture PartnersOUP (Osage University Partners)

Podimetricspodimetrics.cominApr 2022SEC filingmedium confidence

Podimetrics offers a remote monitoring and care program for people with complex diabetes, centered on the SmartMat device that collects foot-health data to enable early intervention and prevent complications such as amputations.

Digital HealthHealthtechMedical DevicesSomerville, US

David Linders(Executive Officer, Director)inJonathan Bloom(Executive Officer, Director)

BoardAaron Sandoski(Director)in

Board seatAlexandra Cantley· per SEC Form D · $60M raise · filed Apr 2022

Co-investorsNorwich VenturesScientific Health DevelopmentSV Health InvestorsRock Health

Satellite Biosatellite.bioSeries A · Mar 2022 · $82M

Satellite Bio develops an off-the-shelf cell therapy that delivers functional liver cells (hepatocytes) into the body, where they engraft to restore liver function.

BiotechHealthtechCambridge, US

Christopher Chen(Director, Promoter)inThomas Lowery(Executive Officer)

BoardEllie McGuire(Director)Ling Wong(Director)Sujata Bhatia(Director)William Young(Director)

Co-investorsAlumni VenturesaMoonCatalio Capital Management, LPLightspeed Venture PartnersHighbury HoldingsS32

TRexBiotrex.bioinSeries A · Mar 2022 · $26M

TRexBio develops biologic medicines targeting inflammation in autoimmune and inflammatory diseases by decoding human tissue biology.

AI & Machine LearningBiotechDeep TechHealthtech

Johnston Erwin(Chief Executive Officer)Ali Zarrin(Chief Scientific Officer)

Co-investorsAvego BioScience CapitalDelos CapitalDementia Discovery FundPfizer Venture InvestmentsSV Health InvestorsAgent Capital

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Amagma, Inc.Be Me HealthCardurion Pharmaceuticals, Inc.Knowledge FactorTessa Therapeutics

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.