Entrepreneur First — 2025 Investments

Sensmore builds Machine Assist, a physical AI system that gives drivers of heavy machinery real-time situational awareness and collision warnings for people, other machines, and static objects.

Advanced ManufacturingAI & Machine LearningConstruction TechDeep TechMobility & TransportationRoboticsBerlin, DE

MRMaximilian Rolf(CEO)inBJBjarne Johannsen(CTO)in

Co-investorsPOPoint NineACAcequia Capital (AceCap)EAEASME – EU Executive Agency for SMEsPRPrototype CapitalTITiny Supercomputer Investment Company

Miist develops inhaled microparticle therapeutics that deliver medicine to the bloodstream in 30 seconds, targeting conditions like migraine, pain, and anxiety where rapid onset is critical.

BiotechDigital HealthHealthtechMedical DevicesAlameda, US

EEEric Ezerins(Cofounder, Head of Technology)inDSDalton Signor(Cofounder, CEO)inRandy Krebs(Executive Officer)JSJeffrey Schuster(Chief Technology Officer)inEvan Alfano(Director)

Co-investorsCACAL InnovationCACalifornia Innovation FundFRFREEFLOWTHThe Innovation SpaceRERefactor Capital

Bubble Robotics builds autonomous underwater robots and AI ("Physical AI") for persistent monitoring, mapping, and inspection of offshore assets and subsea infrastructure such as energy installations and data cables.

AI & Machine LearningDeep TechEnergyIoTRoboticsDover, US

PAPatricia Apostol(CTO)inJCJean Crosetti(CEO @Bubble Robotics)in

Co-investorsTRTranspose Platform ManagementANAngel InvestEPEpisode1

General Reasoning (GR) is an AI research company that trains models to work, communicate, and coordinate over long time horizons, with a focus on reinforcement learning, multi-agent systems, and environment design.

AI & Machine LearningDeep TechDeveloper ToolsSan Francisco, US

RTRoss Taylor(CEO)inCTChengxi Taylor(President)inChengxi Wang(Executive Officer, Director)

BoardThomas Joseph Grady II(Director)Kip Gabriel Parker(Director)

Co-investorsAIAir Street Capital

Genie Fertility develops a discovery platform that uses machine learning and multi-omics analysis to identify molecular biomarkers in uterine lining, leveraging menstrual blood samples to improve reproductive health outcomes and fertility diagnostics.

BiotechDigital HealthFemTechHealthtechLondon, GB

AMAnoushka Menon(CEO)inAHAndreas Hadjimitsis(Cofounder)in

Co-investors3333EastTRTranspose Platform Management

HelmGuard offers an AI security agent platform that embeds AI-driven analysis into security workflows to help security and risk professionals make faster, clearer decisions.

AI & Machine LearningCybersecurityEnterprise SoftwareLondon, GB

JDJohn Daley(CEO & Co-Founder)inJMJack Miller(CTO & Co-Founder)in

Co-investorsFRFrontline VenturesINInfinity VenturesTRTranspose Platform Management

Interface provides a platform that ingests, audits, and operationalizes procedures, standards, and compliance records for industrial operators, giving field crews mobile step-by-step workflows with AI verification and giving leadership real-time visibility.

Advanced ManufacturingAI & Machine LearningEnterprise SoftwareSaaSLondon, GB

TLThomas Lee Young(ceo)inAMAaryan Mehta(CTO)in

Co-investorsTRTranspose Platform ManagementDEDefy PartnersPRPrecursor VenturesRORock Yard Ventures

Jack & Jill builds AI agents to support job seekers and companies in hiring: Jack helps individuals navigate career transitions and job searches with personalized coaching, while Jill assists companies in identifying and recruiting qualified candidates.

AI & Machine LearningFuture of WorkHR TechSaaSLondon, GB

MWMatthew Wilson(Founder)inSMSaaras Mehan(Founder)inMatt Wilson(Founder)

Co-investorsCRCreandumDIDig Ventures Management LimitedEPEpisode1PLPlayfair CapitalTETenacity Capital GlobalTRTrueSight Ventures+4 more

Magdrive develops electric propulsion systems for satellites, specifically the Warlock thruster which uses metal propellant and plasma generation to deliver high thrust in a compact form factor.

Deep TechHardwareSpace TechLondon, GB

TCThomas Clayson(Founder)inMSMark Stokes(Co-founder & CEO)inMark A. Stokes(Founder)

Co-investors7P7percent VenturesALAlumni VenturesBABalerion Space VenturesFOFounders FundOUOutsized VenturesREredalpine

Material Difference builds an explainable AI platform designed to help locate ore-bodies for mining operations.

AI & Machine LearningEnergySan Francisco, US

GYGabriel Yoong(CEO)inLCLuke Cullen(CTO)in

BoardSPSophie Purdom(Director)in

Co-investorsMYMythos Ventures Management, LlcTRTranspose Platform ManagementPLPlaneteer Capital

Mirantus Health is a German health company focused on improving nationwide access to care.

Digital HealthHealthtechBerlin, DE

DPDominik Pederzani(CEO)inClaus Gruber(Cofounder)in

Co-investorsBEBerliner Volksbank VenturesENEnjoyventure ManagementRERedstoneREReventTATane FundNONoaber

Observe provides observability software that helps engineers troubleshoot distributed applications, consolidating logs, metrics, and traces into a single platform built on Snowflake.

AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise SoftwarePalo Alto, US

Qi Jin(Executive Officer)inKBKeith Butler(Executive Officer)inJBJeremy Burton(Executive Officer, Director)inBCBrian Campbell(Executive Officer)inChristine Dorrion(Executive Officer)inJacob Leverich(Founder)in

Co-investorsSUSutter Hill VenturesALAlumni VenturesARArtisanal VenturesBABasecamp FundEVEvolution Equity PartnersHUHuman Capital+8 more

Phagos develops phage therapy treatments as an alternative to antibiotics, using its Alphagos platform that combines microbiology and AI to design targeted bacterial medicines against antimicrobial resistance.

AgTechAI & Machine LearningBiotechIvry-Sur-Seine, FR

APAlexandros Pantalis(Executive Officer, Director)inAJAdèle James(CTO)in

BoardRKRobert Kniaz(Director)inXin Ma(Director)GDGeoffroy Dubus(Director)in

Co-investorsACAcurio VenturesBEBeyond CapitalCACapagroHOHoxton VenturesAGAgFunderCICitizen Capital+3 more

Pharosyn uses AI to continuously monitor clinical trials, regulatory filings, press releases, and earnings calls, and produce strategic competitive intelligence reports on a company's competitors.

AI & Machine LearningBiotechEnterprise SoftwareSaaSLondon, GB

SCStephen Cowley(CEO)inJHJoshua Hampson(CTO)in

Co-investorsMOMoonfire VenturesTRTranspose Platform ManagementGEGeneral Advance

Recornea is developing corneal implants for people with keratoconus, a condition in which the cornea progressively bulges outward.

HealthtechSingapore, SG

ELEmiliano Lepore(CEO)inMoses Kakanga(CTO)in

Co-investorsHEHealth WildcattersSCScientifica Venture CapitalB B HeroesENENEA Tech e Biomedical

Repello provides autonomous red teaming and security testing for AI applications and agents, detecting vulnerabilities through adversarial attack simulation combined with human-like interaction testing.

AI & Machine LearningCybersecurityEnterprise SoftwareBangalore, IN

ABAryaman Behera(Founder)inNMNaman Mishra(Founder)inAryaman Behera Naman Mishra(Founder)

Co-investorsPIpi VenturesCHCharlie SonghurstVEVenture Highway

Replit is a platform for software development that aims to make app creation accessible to non-programmers through intuitive tools and AI agents.

AI & Machine LearningCloud ComputingCreator EconomyData & InfrastructureDeveloper ToolsEdTechEnterprise SoftwareMarketing TechSaaSSan Francisco, US

HAHaya Abdalla(Founder)inAMAmjad Masad(Founder)inHOHaya Odeh(Founder)inLHLuis Héctor Chávez(CTO)Faris Masad(Eng Manager)designer(Founder)

Co-investors13137 Ventures7B7BC Venture CapitalA.A.Capital VenturesABAbstract VenturesAIAIspace VenturesALAllied Venture Partners+66 more

Stockline provides enterprise resource planning software designed for food wholesalers that uses AI agents to automate administrative work like order entry.

AI & Machine LearningEnterprise SoftwareSaaSSan Francisco, US

MOMariem Ould Ismail(CEO)inMDMoncef DJAFRI(CTO)in

Co-investorsINInvestorXKIKima VenturesSTSterling RoadTRTranspose Platform ManagementY Y Combinator2020VC+9 more

The Personal AI Company builds an AI assistant that adapts to how an individual works, handling tasks such as calendar scheduling, drafting emails, and retrieving information.

ConsumerLondon, GB

SJSanskar Jethi(ceo)inAKArsen Kylyshbek(CTO)in

Co-investorsTRTranspose Platform Management

Tracelight builds an AI agent for spreadsheet modelling aimed at financial advisors and dealmakers, with error-checking, source citation, and logging of AI actions.

AI & Machine LearningEnterprise SoftwareFintechLondon, GB

PFPete Fuller(CEO)inJZJanek Zimoch(Founder)inPFPeter Fuller(Founder)in

Co-investorsINInovo VCACAcequia Capital (AceCap)CHChalfen VenturesCHCharlie Songhurst