Tortola · Pre-Seed–Series B
Investment thesis
Early-stage Web3 investor specializing in DeFi and decentralized lending, using a systematic, quantitative, market-structure approach with technologists/mathematicians who take hands-on operational roles in on-chain experiments.
Source: firm website, verified Jul 21, 2026.
What they invest in
from 23 of 40 portfolio companiesCrypto & Web3 ×19Fintech ×9Data & Infrastructure ×7Developer Tools ×7AI & Machine Learning ×6Consumer ×2Social ×2Cloud Computing ×1
HQs:United States×7Japan×1
Investments · 40 tracked
founders shown can be your intro pathBy year:2022 · 12021 · 12015 · 13 dated
FORTH DAO is a decentralized autonomous organization that governs the AMPL token and manages treasury assets through community voting, including protocol-owned liquidity and ecosystem grants in the elastic finance space.
Crypto & Web3FintechSan Francisco, US
Brandon Iles(Founder)inAguilar Gestany(Executive Officer)Karen Lasso(Executive Officer)Emilio Mc Entosh(Executive Officer)
Co-investorsBlack DragonCollab+CurrencyFounder CollectiveMagnus CapitalPantera CapitalSlow Ventures
A MEV-powered staking protocol that allows users to stake $MON tokens and receive $aprMON for use in decentralized finance applications.
Crypto & Web3
Co-investorsPantera Capitalgumi Cryptos Capital (gCC)RainmatterSauce.vc
Co-investorsPlaceholder VCWintermuteJump Crypto
Blast is a blockchain platform that offers yield on USD deposits for users and holders, with an associated mobile application.
Crypto & Web3New York, US
Thomas J. Horan(Executive Officer, Director, Promoter)
BoardMargo Walton(Director)
Co-investorsParadigmStandard CryptoBpifranceExpansion Venture Capital
Capx is an infrastructure runtime for deploying autonomous, agent-run companies, using typed YAML configs to declare AI agents, playbooks, budgets, and governance.
AI & Machine LearningCrypto & Web3Developer Tools
Co-investorsArctic Digital
Eclipse is a Layer 2 blockchain network for Ethereum that runs the Solana Virtual Machine (SVM), combining Solana's execution speed with Ethereum's liquidity to support high-throughput decentralized applications.
Crypto & Web3Developer ToolsFintech
Neel Somani(Founder)Vijay Chetty(CEO)Terry Chung(Head of Strategy)Ben Livshits(CTO)
Co-investorsHack VCDBAFenbushi CapitalMaven 11OKX VenturesPlaceholder+5 more
A modular DPoS network built to power orderbook liquidity.
Co-investorsHack VCMaelstromMysten Labs
Ethena operates a crypto protocol offering USDe, a digital dollar, and sUSDe, a reward-accruing asset backed by collateralized assets with third-party attestations.
Crypto & Web3Fintech
Guy Young(Founder & CEO)in
Co-investorsAlphaLab CapitalBitDAOBreedCaladanCVP NoLimitF-Prime Capital+17 more
Fortunafi brings real-world assets onchain, offering liquidity solutions and investment products such as private and public debt funds with native minting and redemption on major blockchains.
Crypto & Web3FintechMiami, US
Nicholas Garcia(President, Chief Financial Officer and Secretary)
Co-investorsSpace Whale CapitalVine Ventures
BOB is a hybrid Bitcoin/EVM layer built on the OP stack that provides Bitcoin DeFi—swapping, saving, earning, staking, lending, and borrowing with native BTC via BitVM, without wrappers or custodians.
Co-investorsCoinbase VenturesIOSG VenturesRockawayXSignum CapitalSilvermine CapitalWeb3com Ventures+1 more
Heurist provides full-stack AI infrastructure for onchain applications, offering an aggregation layer for Web3 agents with over 100 verifiable crypto tools built on ERC-8004 and x402 payments.
AI & Machine LearningCrypto & Web3Data & InfrastructureNew York City, US
Tao He(Founder)
Co-investorsRR2 Capital
A next-generation OTC derivatives exchange offering perpetual futures trading.
Co-investorsBitDAOMagnus CapitalMantle NetworkThanefield Capital
Ion Protocol is a lending and borrowing platform that lets users lend and borrow against staked and restaked crypto assets without price-based liquidation risk.
AI & Machine LearningCrypto & Web3Fintech
Co-investorsCollider VenturesMaelstromPicks and Shovels (Picks & Shovels)Robot VenturesSevenX Ventures
Lava Network provides decentralized RPC access for interacting with blockchains, handling requests such as trading, swapping, deploying, and staking across multiple chains.
Crypto & Web3Data & InfrastructureDeveloper Tools
YairGil
Co-investorsAlliance DAO (ex DeFi Alliance)AlphaLab CapitalBlack DragonBreakOrbitCaladanDivergence+10 more
Mezo is a Bitcoin-backed lending and yield platform that allows users to borrow stablecoins (MUSD) using Bitcoin as collateral and earn yield through managed vault strategies.
Crypto & Web3Fintech
Matt Luongo(Founder & CEO)
Co-investorsBaseTwoDraper DragonFlowdeskMulticoin CapitalNascentPantera Capital+7 more
Monad is a high-performance EVM-compatible blockchain designed for fast, low-cost transactions.
Cloud ComputingCrypto & Web3Data & Infrastructure
Co-investorsAlphaLab CapitalAmbush CapitalArchetypeBankless VenturesBig Brain HoldingsBloccelerate VC+23 more
Morpho is a decentralized lending protocol that provides enterprise-grade infrastructure for launching lending products.
Crypto & Web3Fintech
Paul Frambot(Founder & CEO)in
Co-investorsEntropy Industrial CapitalFlowdeskIOSG VenturesMirana VenturesMulticoin CapitalPantera Capital+9 more
MyShell is an AI platform for creating images, portraits, filters, and short videos, including a product called MyShell Art with a graphical interface aimed at casual users and digital creators.
AI & Machine LearningConsumerCreator Economy
Co-investorsBankless VenturesChronos VenturesD1 VenturesHyperithmINCE CapitalInception Capital (ex OP Crypto)+3 more
Nillion is a decentralized secure computing network that uses privacy-enhancing technologies to store and process sensitive data by distributing trust across nodes.
AI & Machine LearningCrypto & Web3Data & Infrastructure
Andrew Yeoh(Founder)in
Co-investorsARKN venturesBig Brain HoldingsChapter OneFlowdeskFOMO VenturesInception Capital (ex OP Crypto)+14 more
Co-investorsAndromeda CapitalMoon HoldingsRyze Labs
Ondo builds institutional-grade platforms, assets, and infrastructure for bringing traditional financial markets onchain, including tokenized public securities and US Treasuries usable in DeFi.
Crypto & Web3FintechNew York, US
Nathan Allman(Founder)in
BoardPaul Veradittakit(Director)in
Co-investorsBitDAOChapter OneCoalition OperatorsCoinbase VenturesDigital Currency GroupMantle Network+6 more
Orderly Network provides omnichain infrastructure for launching perpetuals decentralized exchanges (perp DEXs) on any blockchain, offering a shared orderbook and liquidity accessible via SDK or white-label.
Crypto & Web3Data & InfrastructureDeveloper Tools
Ran Yi(Founder)
Co-investorsD1 VenturesDragonflyGate VenturesIOSG VenturesMentha PartnersMetastable+9 more
Praxis is an online community and membership organization working to establish a new city described as a digital nation.
ConsumerSocial
Co-investorsPronomos CapitalWinklevoss Capital
Privy provides infrastructure for building crypto wallets and moving digital assets, enabling developers to integrate wallet functionality, stablecoin transfers, and automated payment systems into their applications.
Crypto & Web3Developer ToolsFintechBoston, US
Asta L.(Founder)inBen Jabbawy(Executive Officer, Director)
BoardSamuel Clemens(Director)
Co-investorsArchetypeBitDAOBlueYard CapitalCoinbase VenturesElectric CapitalLattice Capital+8 more
Co-investorsHypersphere Ventures
UXLINK is a Web3 social platform and infrastructure that connects users and projects through account abstraction and cross-chain functionality.
Crypto & Web3Developer ToolsSocialTokyo, JP
Co-investorsINCE CapitalHashkey CapitalKuCoin Labs
Vana is an open data infrastructure platform that enables individuals to control and manage the data they generate, with the ability to choose how it is used by AI systems.
AI & Machine LearningData & Infrastructure
Art Abal(Founder)
Co-investorsAbstract VenturesAlphaLab CapitalCaladanEarl Grey CapitalParadigmSCB 10X+2 more
Portfolio news
latest coverage across their companiesEthena Labs · interactivecrypto.com · Aug 21, 2026

Elixir · smallcaps.com.au · Aug 12, 2026

Monad · crypto-economy.com · Jul 17, 2026

Ondo Finance · coinfomania.com · Jul 17, 2026

Morpho Labs · kucoin.com · Jul 4, 2026
Blast · wlwt.com · Jun 24, 2026
Eclipse · mercomcapital.com · Jun 17, 2026
Apr · entrackr.com · Apr 25, 2026
Frequently asked questions
- What stage does Manifold Ventures invest at?
- Manifold Ventures invests at the Pre-Seed, Seed, Series B stages.
- What sectors does Manifold Ventures focus on?
- Manifold Ventures focuses on Crypto & Web3.
- Where is Manifold Ventures located?
- Manifold Ventures is headquartered in Tortola, US.
- Does Manifold Ventures lead rounds?
- Manifold Ventures typically participates in rounds rather than leading them.
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