Unorthodox Ventures
Venture capitalAustin · Seed–Growth · 15 people tracked
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Investment thesis
Unorthodox Ventures positions itself as a contrarian VC backed by a single limited partner, enabling fast decisions and a focus on long-term success rather than short-term returns. It invests at seed and Series A, with later-stage follow-ons possible, writing checks of $1M-$5M. Rather than coming from a banking background, its team draws on engineering and marketing expertise to help portfolio companies with PR, manufacturing, and go-to-market strategy for pre-revenue startups. The firm invests globally and frequently helps overseas companies establish their first U.S. offices, offering free space at its 30,000-square-foot Austin warehouse for storage, products, and initial staff.
Source: firm website, verified Sep 26, 2026.
Team · 15 people
from the firm's website & public directoriesWhat they invest in
from 19 of 28 portfolio companiesHealthtech ×14Medical Devices ×13Biotech ×6Deep Tech ×5Digital Health ×5AI & Machine Learning ×3Hardware ×3Robotics ×2
HQs:United States×14France×2Switzerland×1Germany×1Netherlands×1
Who they back
founder profiles across 14 portfolio companiesFounding team size:solo founder×112 founders×13 founders×2
Where their founders studiedfrom 13 founders with education data
Massachusetts Institute of Technology ×2Technical University of Munich ×2
What their founders studiedfrom 13 founders with field-of-study data
Engineering ×8Business & Management ×3Computer Science ×2
Where their founders worked beforefrom 13 founders with career history
Johns Hopkins University ×2
Investments · 28 tracked
founders shown can be your intro pathBy year:2025 · 12024 · 12023 · 52021 · 18 dated
HealthtechLos Gatos, US
Brian Fahey(Executive Officer, Director)inAmr Salahieh(Director)
BoardGAUTAM KAINTH(Director)Bihua Chen(Director)
Co-investorsExcelestar Ventures
Carthera develops SonoCloud®, an implantable ultrasound device that temporarily disrupts the blood-brain barrier to improve drug delivery to the brain for treatment of brain diseases including glioblastoma, brain metastases, and Alzheimer's Disease.
BiotechDeep TechHealthtechMedical DevicesLyon, FR
Alexandre Carpentier(Founder)in
Co-investorsSupernovaAgoranovSupernova InvestPanakes Partners
Conkay Medical is a medical device company developing technologies focused on cardiovascular care.
HealthtechMedical Devices
Albert Yuan(Founder)in
Co-investorsAngel Physicians Fund
Corflow develops diagnostic and therapeutic solutions to restore healthy microvascular blood flow in the human body, serving the cardiovascular medical device industry.
HardwareHealthtechMedical Devices
Martin(Physician Co-Founder)Rick Geoffrion(Chairman and CEO)
Co-investors415 CapitalBroadview VenturesLaerdal Million Lives FundPanakes PartnersKorysMérieux Equity Partners+1 more
Corporis Medical develops medical devices for surgical and diagnostic applications, focusing on innovations like perfusion measurement systems and clinical validation.
BiotechDeep TechDigital HealthHealthtechMedical DevicesMaastricht, NL
Alexander Veenhof(Surgeon, MD, Founder)in
Co-investorsInkefBrightlands Venture Partners
DiaMonTech develops non-invasive glucose measurement technology based on infrared spectroscopy for medical device applications.
Deep TechDigital HealthMedical DevicesBerlin, DE
Thorsten Lubinski(CEO & Co-Founder)inWerner(Co-founder)Sergius(COO)
Co-investorsAescuvestAuxxoCompanistoSamsung NextIBB Ventures
Exero Medical develops the xBar system, which uses electrode sensors embedded in a standard surgical drain to non-invasively monitor post-operative tissue healing and detect anastomotic leaks after gastrointestinal surgery.
BiotechDigital HealthHealthtechMedical Devices
Erez Shor(CEO)inMatan Ben David(Medical Director)
Co-investorsLongevity Venture PartnersTech Council VenturesIsrael Innovation Authority
Flott is a fleet management platform that unifies telematics, business systems, and external data to provide enriched operational visibility and automate workflows for fleet, equipment, and site management.
AI & Machine LearningEnterprise SoftwareLogistics & Supply ChainSaaSParis, FR
Sylvanus MAHE(Co-Founder & CEO)inKanvaly Fadiga(Founder)in
Co-investorsBlast.ClubY CombinatorGuil Mobility VenturesTeam Ignite
KewaZo builds construction automation technology, including robotic systems for material transport at industrial and construction sites, aimed at reducing crane time and improving safety.
Construction TechHardwareRobotics
Ekaterina Grib(Founder)inArtem Kuchukov(Founder)inLeonidas Pozikidis(Founder)in
Co-investorsAtlas Ventures (UK)Schooner CapitalTrue VenturesBenson CapitalChevron Technology VenturesCybernetix Ventures+3 more
Laplace Interventional develops a transcatheter tricuspid valve replacement system that delivers a prosthetic valve percutaneously, avoiding open-heart surgery for patients with tricuspid regurgitation.
HealthtechMedical DevicesPlymouth, US
Ramji Iyer(Executive Officer, Director)in
BoardJenny H. Barba(Director)Todd Mortier(Director)Colin Morrison(Director)
Co-investorsAphelion CapitalFeatures Capital Holdingsgener8torShangBay Capital LLCAphelion CardeationEngage Venture Partners
Laza Medical develops an AI- and robotics-powered ultrasound imaging system for structural heart, electrophysiology, and diagnostic cardiac procedures, combining real-time 3D heart modeling, procedural guidance, and robotic probe control.
AI & Machine LearningBiotechMedical DevicesRoboticsCampbell, US
Amr Salahieh(Executive Officer, Director, Promoter)Pablo Garcia Kilroy(General Manager)inCasey Gordon(Director)Mariam Maghribi(Executive Officer)David Voris(Executive Officer)
Co-investors415 CapitalPage One VenturesThe Capital Partnership
Lumen operates a platform focused on commercial real estate (CRE) energy transactions, connecting CRE owners with qualified demand backed by trusted analysis.
CleantechEnergyPropTechSan Francisco, US
Dave Coen(Founder)inMichael Sachdev(Director)Peter Light(CEO)in
BoardPoonam Sharma(Director)
Co-investorsDesigner FundEsplanade VenturesKreos CapitalMoxxie VenturesNovel CapitalThird Derivative+3 more
Shifamed develops and brings to market medical devices designed to address unmet clinical needs in healthcare.
Deep TechHealthtechMedical Devices
Amr Salahieh(Founder)inClaudio Argentoin
Co-investorsExcelestar VenturesAmed VenturesQatar Investment Authority
Sonavex develops medical device technologies focused on vascular access and related clinical applications, drawing on ultrasound-based imaging and monitoring products.
BiotechDigital HealthHealthtechMedical DevicesBaltimore, US
David Narrow(Executive Officer, Director)inDevin O'Brien-Coon(Co-Founder & Chairman)inJerry L. Prince(Co-Founder)inJohn Rappe(Executive Officer)inAlex Yevzlin(Executive Officer)
BoardRobert Hallenbeck(Director)
Co-investorsFusionJStar Capital InvestmentsKeiretsu ForumMaryland TEDCORembrandt Venture PartnersRiptide Ventures+2 more
Supira Medical develops a next-generation percutaneous ventricular assist device (pVAD) to provide temporary mechanical circulatory support for high-risk patients undergoing coronary interventions and those in cardiogenic shock.
HardwareHealthtechMedical DevicesCampbell, US
Nitin Salunke(President & CEO)inJean Orth(Executive Officer)Mariam Maghribi(Executive Officer, Director)
BoardCasey Gordon(Director)Christopher Shen(Director)Bihua Chen(Director)
Co-investors415 CapitalAmed VenturesThe Capital PartnershipNovo HoldingsQatar Investment Authority
Third Pole develops portable and miniaturized devices that generate inhaled nitric oxide on-demand for hospital and mobile treatment of severe cardiopulmonary diseases and lung infections.
AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesWaltham, US
Elizabeth Holmberg(CFO and Treasurer)Basil Athenson(Chief Executive Officer and President)Bill Athenson(Chief Executive Officer)inGordon Kinder(Chief Financial Officer)Philip Silkoff(Chief Medical Officer)David Zapol(Director)
Co-investorsSaturn Partners
Vibrant Gastro develops a drug-free medical device using micro-vibrations to treat chronic idiopathic constipation in adults.
ConsumerDigital HealthHealthtechMedical DevicesItasca, US
Lior Ben Tsur(CEO & Co-Founder)in
PartnerCarey Smith· solo GP
Co-investorsGefen CapitalSequoia Capital
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AfiaAkura MedicalAninaAwkward EssentialsCatheraElucidFirmusGendaTushyVibrantZippsafe
Portfolio news
latest coverage across their companiesShifamed · trysignalbase.com · May 12, 2026
Kewazo · finsmes.com · Mar 19, 2026
Flott HQ · ycombinator.com · May 27, 2025
Frequently asked questions
- How many investments has Unorthodox Ventures made?
- Unorthodox Ventures has 28 tracked investments, including 2 dated in the last 24 months.
- What stage does Unorthodox Ventures invest at?
- Unorthodox Ventures invests at the Seed, Series A, Series B, Growth stages.
- What is Unorthodox Ventures's typical check size?
- Unorthodox Ventures typically writes checks of $1M – $5M.
- What sectors does Unorthodox Ventures focus on?
- Unorthodox Ventures focuses on Biotech, Construction Tech, Consumer, Digital Health, Medical Devices, Sector Agnostic.
- Where is Unorthodox Ventures located?
- Unorthodox Ventures is headquartered in Austin, US.
- Who does Unorthodox Ventures co-invest with?
- Unorthodox Ventures most often shares deals with 415 Capital, Kreos Capital, Maryland TEDCO, among 43 tracked co-investors.
Media · Podcasts & interviews
featuring the teamFireside chat with Carey Smith, Unorthodox Ventures hosted by Jan Ameri, ArcticStartup
ArcticStartup · Carey Smith
Carey Smith, Founder Unorthodox Ventures, Chief Big Ass Fans, sold for $500Million
Eliances.com · Carey Smith
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