Twin Path Ventures — Full Portfolio

Co-investorsCambridge Angels group

AMPLY Discovery is a UK-based biotech company that uses AI and computational biology to identify therapeutic targets in non-coding regions of the genome and develop first-in-class drugs through an integrated discovery platform combining machine learning with wet-lab validation.

AI & Machine LearningBiotechDeep TechHealthtechBelfast, GB

Oliver Rausch(CSO)in

Co-investorsClarendon Fund Managers Ltd.TechstarsQUBIS

Ayora is a platform for law firms that uses AI to automate matter pricing, budget management, and financial reporting by enriching legal practice data.

AI & Machine LearningEnterprise SoftwareLegalTechSaaS

Stefan Ciesla(Founder)Gordon McKenzie(Founder, PhD)in

Co-investorsJ12 Ventures

Azoma is an Answer Engine Optimization (AEO) and Agentic Commerce Optimization (ACO) software platform that helps consumer brands and retailers track, optimize, and increase how AI shopping agents (ChatGPT, Google Gemini, Amazon Rufus, Walmart Sparky, Perplexity) discover, rank, and recommend their products.

AI & Machine LearningE-commerceMarketing TechToronto, CA

Max Sinclair(Founder)

Cardiovolt is an AI platform that analyzes standard 12-lead ECG signals and images to detect subtle digital biomarkers, predicting cardiovascular disease risk before symptoms appear.

AI & Machine LearningDigital HealthMedical Devices

Composo provides AI evaluation and monitoring for production systems, automatically detecting failure patterns in LLM outputs and deploying guardrails to block bad outputs before they reach users.

AI & Machine LearningDeveloper ToolsEnterprise Software

DeepMirror develops AI software for hit-to-candidate molecule design in drug discovery, enabling teams to generate novel chemical candidates and predict molecular properties using proprietary data while maintaining strict data privacy and IP security.

AI & Machine LearningBiotechDeep Tech

Co-investorsExcellis Holding

EnAcuity develops AI-powered software for real-time surgical image enhancement using hyperspectral imaging, delivered as a software-only solution that integrates with existing operating room equipment.

AI & Machine LearningHealthtechMedical DevicesKensington, GB

Fifth Dimension AI is a decision intelligence platform for real-assets investors and managers that connects to systems like Yardi, Argus, Dealpath, and SharePoint to automate deal screening, lease abstraction, due diligence, and portfolio risk monitoring.

AI & Machine LearningFintechPropTech

Johnny Morris(Founder)in

Co-investorsAnthemis VentureLove VenturesMMC VenturesPrudenceSie VenturesAFG Partners+2 more

FinCrime Dynamics provides fraud red team testing services to help financial institutions and fintech companies identify and strengthen weaknesses in their fraud controls through bespoke threat scenario testing and expert analysis.

AI & Machine LearningCybersecurityEnterprise SoftwareFintechCambridge, GB

Stephen Quick(Founder & Director)Daniel Turner-Szmykiewicz(Founder & Director)

Co-investorsOxfordOxford Investment Opportunity Network (OION)SyndicateRoom

FUTURESEARCH builds forecasting and prediction tools.

AI & Machine LearningData & InfrastructureSaaSSector AgnosticSan Bruno, US

Dan Schwarz(Founder)inPeter Mühlbacher(Founder)Daniel Hnyk(Founder)Nikos Bosse(Founder)Jack Wildman(Founder)McKenna Meyer(Founder)

Co-investorsJuniper Ventures Management, LlcMetaplanet

HotHouse Therapeutics uses artificial intelligence and synthetic biology to reprogram plant biosynthetic pathways to create novel pharmaceutical compounds not achievable through traditional chemical synthesis.

AI & Machine LearningBiotechDeep TechNorwich, GB

Professor Anne Osbourn OBE FRS FLS(Chief Science Officer)Dr David Sheppard(Chief Executive Officer)

Co-investorsCambridge Angels groupFuture Planet CapitalUK Innovation & Science Seed Fund

iGent AI builds Maestro, an AI software engineering agent that plans and autonomously writes, executes, tests, and validates code in secure cloud-based sandboxes.

AI & Machine LearningDeveloper ToolsSaaSLondon, GB

Martin Szummer(Founder)

Co-investors10x FoundersXTX Markets

InsureVision builds VisionScore, a vision-transformer system that analyses forward-facing dashcam footage to produce per-driver behavioural risk scores, continuous post-bind monitoring, and real-time crash detection with FNOL.

AI & Machine LearningInsurTechMobility & Transportation

Co-investorsRethink Ventures

Co-investorsFuel VenturesXTX Markets

Ledger Rocket provides accounting automation and operational intelligence for product launches, offering AI-powered assistance to streamline financial treatments and unified visibility across business activity.

AI & Machine LearningData & InfrastructureEnterprise SoftwareFintechSaaS

Mater-AI designs novel thermoelectric materials using AI, physics-based modelling, quantum methods, and lab validation, aiming for higher efficiency without toxic or rare earth elements.

AI & Machine LearningDeep TechNew Materials

Co-investorsOne Planet Capital

Optifi is a pricing optimization software platform and service that helps eCommerce businesses set prices, promotions, and delivery rates to improve revenue, margins, and growth.

E-commerceRetail TechSaaS

PentaBind designs programmable aptamers—small RNA/DNA molecules with sub-nanomolar binding affinity—for continuous sensing and diagnostics applications (e.g., monitoring hormones and biomarkers) and targeted therapeutics in oncology and drug delivery.

BiotechDeep TechMedical DevicesLondon, GB

Rory Ryan(Founder)inPhil Haynes(Founder)inMiguel Gonzalez Canudas(Founder)

Co-investorsEntrepreneur FirstHoxton Ventures

Recurse ML is an AI-powered code review tool that analyzes a team's codebase to automatically identify bugs, detect breaking changes, and suggest fixes before code is merged.

AI & Machine LearningDeveloper ToolsSaaSLondon, GB

Jack Jackson(CEO)inArmins Stepanjans(CTO)in

Co-investorsEntrepreneur FirstPlayfair Capital

Sagittal builds Neo, an AI tool for the software development lifecycle that adapts to how development teams work.

AI & Machine LearningCybersecurityDeveloper ToolsEnterprise SoftwareSaaS

Co-investorsSINEWAVE VENTURESFuel Ventures

Sentinal4D develops interpretable machine learning tools for analyzing 3D and 4D cell morphology in drug discovery and mechanistic biology.

AI & Machine LearningBiotechDeep TechHealthtech

Sention Technologies provides measurement and data solutions for battery development and manufacturing, using ultrasound, X-ray computed tomography, and electrochemical testing combined with AI to improve battery quality, efficiency, and safety.

AI & Machine LearningDeep TechEnergyLondon, GB

Co-investorsEndgame CapitalFuture Planet CapitalUK Innovation & Science Seed FundThird Sphere

SUMMETIX builds an insights platform and contact center solution serving financial services, banking, and manufacturing sectors.

AI & Machine LearningData & InfrastructureEnterprise SoftwareMarketing TechSaaS

The Evidence Company builds an explainable AI (XAI) platform for healthcare that quantifies its own uncertainty, traces decisions to source evidence, and flags unreliable LLM outputs so clinicians know when to trust them.

AI & Machine LearningDigital HealthHealthtech

TileBio develops self-supervised AI foundation models for digital pathology, applied to cancer diagnosis, prognosis, biomarker discovery, and drug development.

AI & Machine LearningBiotechDigital HealthMedical Devices

Christopher Walsh(Co-Founder / CEO & CTO)Ke Yuan(Co-Founder / CSO)inDavid Chang(Co-Founder / CMO)John Le Quesne(Co-Founder / CMO)

Co-investorsScottish Enterprise

TILKI builds multiplayer open-world sandbox games as living worlds using AI, allowing creators to define a game world's vision and characters while the AI system simulates the entire world, generates unscripted stories, and handles game asset creation and world-building.

AI & Machine LearningGaming

Co-investorsSFC Capital

London, GB

Caroline Grey(Founder)Jonathan Horn(Founder)in

Co-investorsAlbionVCEndeit CapitalJanuary VenturesNotion CapitalRLC Ventures

Cambridge, GB

Marco Basaldella(Founder)Rebekka Mikkola(Founder)

Vectify is an AI company founded by researchers with backgrounds in machine learning and experience at leading technology companies.

AI & Machine LearningData & InfrastructureDeveloper Tools

Voice-Swap provides AI voice infrastructure that combines voice modelling, generation, and rights management, offering text-to-speech, AI singing voices, and custom proprietary voice models with ownership and rights protection.

AI & Machine LearningCreator EconomyMedia & Entertainment

A company developing recursively self-improving AI systems and autoresearch technology that achieves human-level performance on complex technical tasks through self-optimization loops.

AI & Machine LearningDeep TechDeveloper ToolsLondon, GB

Zhengyao Jiang(Co-founder & CEO)inYuxiang Wu(Co-founder & CTO)in

Co-investorsFounder Collective

Wholesum analyzes large volumes of open-ended, qualitative human responses using statistical inference and machine learning to surface patterns, risks, and early signals such as purchase intent and adoption barriers.

AI & Machine LearningData & InfrastructureEnterprise SoftwareMarketing Tech

Emily Kucharski(Co-founder & CEO)inAdam Kucharski(Co-founder)in

Co-investorsLove VenturesVentures Together