🦊/Investors

Twin Path Ventures

Venture capital

London · Pre-Seed–Growth · 4 people tracked

Find your way into Twin Path Ventures

1,029 people in our graph share verified history with the Twin Path Ventures team — schools, employers, funds. One of them is your warm intro.

Hannah Sealunlockedknows Katie Lockwood · together at University of Cambridge (overlapped)
knows the team · via BPP University
×2knows the team · via University of Oxford
×3knows the team · via University of Cambridge
×2knows the team · via UCL
×3knows the team · via University of Leeds
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Investment thesis

Twin Path Ventures backs highly ambitious, technically strong founders building AI-first products, providing first cheques at the earliest and most daring stages. The firm has invested in AI since 2014 and applies proprietary technical due diligence, believing the initial challenge for startups is engineering. Its fund structure is designed to generate returns two ways: from ambitious founders building large businesses that raise multiple rounds and eventually IPO, and from highly technical founders who prove their technology commercially and exit early within a 3-5 year window. The firm invests across Frontier AI research, AI infrastructure ('Picks & Shovels' such as data platforms and ML Ops), and Applied AI solving real-world problems.

Source: firm website, verified Aug 3, 2026.

Stage
Pre-Seed–Growth
Check
$952.5K
HQ
London, GB
Leads rounds
Leads
Instruments
Equity
Founded
2014
Last 12 months
2 investments
Net assets · FY2025
$135.1K
Tracked investments
42

Team · 4 people

from public directories
Katie Lockwood· Partnerin

What they invest in

from 32 of 42 portfolio companies

AI & Machine Learning ×30SaaS ×10Deep Tech ×8Enterprise Software ×7Biotech ×6Developer Tools ×6Data & Infrastructure ×5Fintech ×5

HQs:United Kingdom×13Canada×1United States×1

Who they back

founder profiles across 15 portfolio companies
47%
solo founders
7 of 15 mapped founding teams
35%
repeat founders
of 31 founders with career history

Founding team size:solo founder×72 founders×53 founders×14+ founders×2

Where their founders studiedfrom 30 founders with education data

University of Cambridge ×4Imperial College London ×3UCL ×3University of Bristol ×3Massachusetts Institute of Technology ×2The University of Manchester ×2University of Exeter ×2

What their founders studiedfrom 29 founders with field-of-study data

Computer Science ×10Mathematics & Statistics ×10Engineering ×4Business & Management ×3Medicine ×3Economics ×2Humanities ×2Life Sciences ×2

Where their founders worked beforefrom 31 founders with career history

Metaculus ×6University of Glasgow ×3BigHand ×2Cancer Research UK Scotland Institute ×2GSK ×2University of Southampton ×2

Accelerator rootsportfolio companies that came through a program

Entrepreneur First ×2

13 founders hold a PhD (of 30 with degree data)

Investments · 42 tracked

founders shown can be your intro path

By year:2026 · 22025 · 22024 · 12023 · 16 dated

Afternoonafternoon.co.ukin

Afternoon builds data and AI infrastructure for financial advisers, designed to reduce administrative work and connect fragmented systems.

AI & Machine LearningFintechSaaSGlasgow, GB

Co-investorsRecursive Ventures

Amplygetamply.coinMay 2025 · $1.8M

Amply is a store operations platform that moves daily retail workflows from paper and spreadsheets into a single app, offering task checklists, scheduled SOPs, digital store visit audits, a communication feed, and AI-powered image verification for visual merchandising.

AI & Machine LearningRetail TechSaaS

Anshul Goyal(Founder)in

Co-investorsIIMA VenturesBritish Business BankClarendon Fund Managers Ltd.QUBISTechstarsventure / science

AMPLY Discoveryamplydiscovery.comin

AMPLY Discovery is a UK-based biotech company that uses AI and computational biology to identify therapeutic targets in non-coding regions of the genome and develop first-in-class drugs through an integrated discovery platform combining machine learning with wet-lab validation.

AI & Machine LearningBiotechDeep TechHealthtechBelfast, GB

Oliver Rausch(CSO)in

Co-investorsClarendon Fund Managers Ltd.TechstarsQUBIS

Ayoraayora.aiinMar 2024 · $1.6M

Ayora is a platform for law firms that uses AI to automate matter pricing, budget management, and financial reporting by enriching legal practice data.

AI & Machine LearningEnterprise SoftwareLegalTechSaaS

Stefan Ciesla(Founder)inGordon McKenzie(Founder, PhD)in

Co-investorsJ12 Ventures

Azomaazoma.aiin𝕏

Azoma is an Answer Engine Optimization (AEO) and Agentic Commerce Optimization (ACO) software platform that helps consumer brands and retailers track, optimize, and increase how AI shopping agents (ChatGPT, Google Gemini, Amazon Rufus, Walmart Sparky, Perplexity) discover, rank, and recommend their products.

AI & Machine LearningE-commerceMarketing TechToronto, CA

Max Sinclair(Founder)in

Cardiovoltcardiovolt.aiin

Cardiovolt is an AI platform that analyzes standard 12-lead ECG signals and images to detect subtle digital biomarkers, predicting cardiovascular disease risk before symptoms appear.

AI & Machine LearningDigital HealthMedical Devices

Arunashis Sau(Founder)in

Composocomposo.aiin

Composo provides AI evaluation and monitoring for production systems, automatically detecting failure patterns in LLM outputs and deploying guardrails to block bad outputs before they reach users.

AI & Machine LearningDeveloper ToolsEnterprise Software

Deepmirrordeepmirror.aiin

DeepMirror develops AI software for hit-to-candidate molecule design in drug discovery, enabling teams to generate novel chemical candidates and predict molecular properties using proprietary data while maintaining strict data privacy and IP security.

AI & Machine LearningBiotechDeep Tech

Co-investorsExcellis HoldingClub degli Investitori

Dimension AIdimensionai.cominOct 2023

Dimension AI is a precedent-based SEC filing software that extracts and structures data verbatim from public EDGAR filings to draft, benchmark, and review documents such as annual reports, capital markets filings (S-1, 424(b)), and N-2 reports for registered funds.

AI & Machine LearningFintechLegalTech

Co-investorsAUTHENTIC VENTURESAbstract VenturesAscension VenturesFelicis VenturesLove VenturesMVP+4 more

EnAcuityenacuity.comin𝕏

EnAcuity develops AI-powered software for real-time surgical image enhancement using hyperspectral imaging, delivered as a software-only solution that integrates with existing operating room equipment.

AI & Machine LearningHealthtechMedical DevicesKensington, GB

Tobias Czempielin

Fifth Dimensionfifthdimensionai.comin

Fifth Dimension AI is a decision intelligence platform for real-assets investors and managers that connects to systems like Yardi, Argus, Dealpath, and SharePoint to automate deal screening, lease abstraction, due diligence, and portfolio risk monitoring.

AI & Machine LearningFintechPropTech

Johnny Morris(Founder)in

Co-investorsAnthemis VentureLove VenturesMMC VenturesPrudenceSie VenturesAFG Partners+2 more

FinCrime Dynamicsfincrimedynamics.comin

FinCrime Dynamics provides fraud red team testing services to help financial institutions and fintech companies identify and strengthen weaknesses in their fraud controls through bespoke threat scenario testing and expert analysis.

AI & Machine LearningCybersecurityEnterprise SoftwareFintechCambridge, GB

Stephen Quick(Founder & Director)inDaniel Turner-Szmykiewicz(Founder & Director)

Co-investorsOxfordOxford Investment Opportunity Network (OION)SyndicateRoomOutrun Ventures

FutureSearchfuturesearch.aiin𝕏

FUTURESEARCH builds forecasting and prediction tools.

AI & Machine LearningData & InfrastructureSaaSSector AgnosticSan Bruno, US

Dan Schwarz(Founder)inPeter Mühlbacher(Founder)inDaniel Hnyk(Founder)inNikos Bosse(Founder)inJack Wildman(Founder)inMcKenna Meyer(Founder)in

Co-investorsJuniper Ventures Management, LlcMetaplanet

HotHouse Therapeutics Seedhothousetx.comin

HotHouse Therapeutics uses artificial intelligence and synthetic biology to reprogram plant biosynthetic pathways to create novel pharmaceutical compounds not achievable through traditional chemical synthesis.

AI & Machine LearningBiotechDeep TechNorwich, GB

Professor Anne Osbourn OBE FRS FLS(Chief Science Officer)Dr David Sheppard(Chief Executive Officer)

Co-investorsCambridge Angels groupFuture Planet CapitalUK Innovation & Science Seed Fund

Igentigent.aiin𝕏

iGent AI builds Maestro, an AI software engineering agent that plans and autonomously writes, executes, tests, and validates code in secure cloud-based sandboxes.

AI & Machine LearningDeveloper ToolsSaaSLondon, GB

Martin Szummer(Founder)in

Co-investors10x FoundersXTX Markets

Insurevisioninsurevision.ai

InsureVision builds VisionScore, a vision-transformer system that analyses forward-facing dashcam footage to produce per-driver behavioural risk scores, continuous post-bind monitoring, and real-time crash detection with FNOL.

AI & Machine LearningInsurTechMobility & Transportation

Mark Miller(Founder)in

Co-investorsRethink Ventures

Ledgerrocketledgerrocket.comin

Ledger Rocket provides accounting automation and operational intelligence for product launches, offering AI-powered assistance to streamline financial treatments and unified visibility across business activity.

AI & Machine LearningData & InfrastructureEnterprise SoftwareFintechSaaS

Laurence Hook(Founder)inJeremie Vaislic(Founder)in

Mater Aimater-ai.comin

Mater-AI designs novel thermoelectric materials using AI, physics-based modelling, quantum methods, and lab validation, aiming for higher efficiency without toxic or rare earth elements.

AI & Machine LearningDeep TechNew Materials

Co-investorsOne Planet Capital

Optifigetoptifi.comin

Optifi is a pricing optimization software platform and service that helps eCommerce businesses set prices, promotions, and delivery rates to improve revenue, margins, and growth.

E-commerceRetail TechSaaS

Pentabindpentabind.com

PentaBind designs programmable aptamers—small RNA/DNA molecules with sub-nanomolar binding affinity—for continuous sensing and diagnostics applications (e.g., monitoring hormones and biomarkers) and targeted therapeutics in oncology and drug delivery.

BiotechDeep TechMedical DevicesLondon, GB

Rory Ryan(Founder)inPhil Haynes(Founder)inMiguel Gonzalez Canudas(Founder)in

Co-investorsEntrepreneur FirstHoxton Ventures

RecurseMLrecurse.ml𝕏

Recurse ML is an AI-powered code review tool that analyzes a team's codebase to automatically identify bugs, detect breaking changes, and suggest fixes before code is merged.

AI & Machine LearningDeveloper ToolsSaaSLondon, GB

Jack Jackson(CEO)inArmins Stepanjans(CTO)in

Co-investorsEntrepreneur FirstPlayfair Capital

Sagittalsagittal.aiin𝕏

Sagittal builds Neo, an AI tool for the software development lifecycle that adapts to how development teams work.

AI & Machine LearningCybersecurityDeveloper ToolsEnterprise SoftwareSaaS

Co-investorsSINEWAVE VENTURESFuel Ventures

Sentinal4Dsentinal4d.comin𝕏

Sentinal4D develops interpretable machine learning tools for analyzing 3D and 4D cell morphology in drug discovery and mechanistic biology.

AI & Machine LearningBiotechDeep TechHealthtech

Matt De Vries(Founder)inChris Bakalin

Sention Technologies Seedsention.io

Sention Technologies provides measurement and data solutions for battery development and manufacturing, using ultrasound, X-ray computed tomography, and electrochemical testing combined with AI to improve battery quality, efficiency, and safety.

AI & Machine LearningDeep TechEnergyLondon, GB

Co-investorsEndgame CapitalFuture Planet CapitalUK Innovation & Science Seed FundThird Sphere

Summetixsummetix.comin

SUMMETIX builds an insights platform and contact center solution serving financial services, banking, and manufacturing sectors.

AI & Machine LearningData & InfrastructureEnterprise SoftwareMarketing TechSaaS

Theevidencecompanytheevidencecompany.comin

The Evidence Company builds an explainable AI (XAI) platform for healthcare that quantifies its own uncertainty, traces decisions to source evidence, and flags unreliable LLM outputs so clinicians know when to trust them.

AI & Machine LearningDigital HealthHealthtech

TileBiotilebio.cominMar 2026

TileBio develops self-supervised AI foundation models for digital pathology, applied to cancer diagnosis, prognosis, biomarker discovery, and drug development.

AI & Machine LearningBiotechDigital HealthMedical Devices

Christopher Walsh(Co-Founder / CEO & CTO)Ke Yuan(Co-Founder / CSO)inDavid Chang(Co-Founder / CMO)inJohn Le Quesne(Co-Founder / CMO)in

Co-investorsScottish Enterprise

TILKItilki.comAug 2025

TILKI builds multiplayer open-world sandbox games as living worlds using AI, allowing creators to define a game world's vision and characters while the AI system simulates the entire world, generates unscripted stories, and handles game asset creation and world-building.

AI & Machine LearningGaming

Co-investorsSFC Capital

Treeferatreefera.comin

London, GB

Caroline Grey(Founder)Jonathan Horn(Founder)in

Co-investorsAlbionVCEndeit CapitalJanuary VenturesNotion CapitalRLC VenturesBackingMinds

Trismiktrismik.comin

Cambridge, GB

Marco Basaldella(Founder)Rebekka Mikkola(Founder)

Vectifyvectify.aiin𝕏

Vectify is an AI company founded by researchers with backgrounds in machine learning and experience at leading technology companies.

AI & Machine LearningData & InfrastructureDeveloper Tools

Voice Swapvoice-swap.ai𝕏

Voice-Swap provides AI voice infrastructure that combines voice modelling, generation, and rights management, offering text-to-speech, AI singing voices, and custom proprietary voice models with ownership and rights protection.

AI & Machine LearningCreator EconomyMedia & Entertainment

Wecoweco.aiin𝕏

A company developing recursively self-improving AI systems and autoresearch technology that achieves human-level performance on complex technical tasks through self-optimization loops.

AI & Machine LearningDeep TechDeveloper ToolsLondon, GB

Zhengyao Jiang(Co-founder & CEO)inYuxiang Wu(Co-founder & CTO)in

Co-investorsFounder Collective

WholeSumwholesum.techinJan 2026

Wholesum analyzes large volumes of open-ended, qualitative human responses using statistical inference and machine learning to surface patterns, risks, and early signals such as purchase intent and adoption barriers.

AI & Machine LearningData & InfrastructureEnterprise SoftwareMarketing Tech

Emily Kucharski(Co-founder & CEO)inAdam Kucharski(Co-founder)in

Co-investorsLove VenturesVentures Together

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

AI-powered ophthalmology platformAisthesis MedicalAisthesismedEcomtentEye2GeneInframindJenesysShield Space

Portfolio news

latest coverage across their companies

Principals & officers · per Companies House

what is this? ⓘ
Katie Emma Lockwood

Director · British · since 2023

Nicholas David Slater

Director · British · since 2023

John Brian Spindler

Director · British · since 2023

Ownership & control

Katie Emma Lockwood25–50% of shares, 25–50% of voting rights, right to appoint and remove directors

Nicholas David Slater25–50% of shares, 25–50% of voting rights, right to appoint and remove directors

John Brian Spindler25–50% of shares, 25–50% of voting rights, right to appoint and remove directors

Frequently asked questions

How many investments has Twin Path Ventures made?
Twin Path Ventures has 42 tracked investments, including 4 dated in the last 24 months.
What stage does Twin Path Ventures invest at?
Twin Path Ventures invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth stages.
What is Twin Path Ventures's typical check size?
Twin Path Ventures typically writes checks of $952.5K.
What sectors does Twin Path Ventures focus on?
Twin Path Ventures focuses on AI & Machine Learning, Data & Infrastructure, Enterprise Software, Fintech, Healthtech, SaaS.
Where is Twin Path Ventures located?
Twin Path Ventures is headquartered in London, GB.
Does Twin Path Ventures lead rounds?
Yes, Twin Path Ventures leads investment rounds.
Who does Twin Path Ventures co-invest with?
Twin Path Ventures most often shares deals with Cambridge Angels group, Entrepreneur First, Future Planet Capital, among 28 tracked co-investors.

Media · Podcasts & interviews

featuring the team

John Spindler | General Partner, Twin Path Ventures

FounderCatalyst · John Spindler

John Spindler of Twin Path Ventures - Investing in AI: A Venture Capital Perspective

Purpose to Performance from Aimava · John Spindler

Images

Twin Path Ventures photo

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